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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

MARKET PLACE

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API

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

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Data Compilation #PharmaFlow

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GLOBAL SALES INFORMATION

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Chemistry

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Also known as: 531-95-3, (s)-3-(4-hydroxyphenyl)chroman-7-ol, (s)-equol, (-)-(s)-equol, S-equol, (-)-equol
Molecular Formula
C15H14O3
Molecular Weight
242.27  g/mol
InChI Key
ADFCQWZHKCXPAJ-GFCCVEGCSA-N
FDA UNII
2T6D2HPX7Q

S-Equol
A non-steroidal ESTROGEN generated when soybean products are metabolized by certain bacteria in the intestines.
1 2D Structure

S-Equol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol
2.1.2 InChI
InChI=1S/C15H14O3/c16-13-4-1-10(2-5-13)12-7-11-3-6-14(17)8-15(11)18-9-12/h1-6,8,12,16-17H,7,9H2/t12-/m1/s1
2.1.3 InChI Key
ADFCQWZHKCXPAJ-GFCCVEGCSA-N
2.1.4 Canonical SMILES
C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O
2.1.5 Isomeric SMILES
C1[C@H](COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O
2.2 Other Identifiers
2.2.1 UNII
2T6D2HPX7Q
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (+-)-isomer Of Equol

2. 3' Hydroxy Equol

3. 3'-hydroxy-equol

4. 4' Methoxy 7 Isoflavanol

5. 4' O Methyl Equol

6. 4'-methoxy-7-isoflavanol

7. 4'-o-methyl Equol

8. 6' Hydroxy Equol

9. 6'-hydroxy-equol

10. Equol, 4'-o-methyl

2.3.2 Depositor-Supplied Synonyms

1. 531-95-3

2. (s)-3-(4-hydroxyphenyl)chroman-7-ol

3. (s)-equol

4. (-)-(s)-equol

5. S-equol

6. (-)-equol

7. 4',7-dihydroxyisoflavan

8. (s)-3,4-dihydro-3-(4-hydroxyphenyl)-2h-1-benzopyran-7-ol

9. 4',7-isoflavandiol

10. 2h-1-benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, (3s)-

11. 2t6d2hpx7q

12. Chembl198877

13. (3s)-3-(4-hydroxyphenyl)-3,4-dihydro-2h-1-benzopyran-7-ol

14. Chebi:34741

15. (s)-(-)-4',7-isoflavandiol

16. (3s)-3-(4-hydroxyphenyl)chroman-7-ol

17. (3s)-3,4-dihydro-3-(4-hydroxyphenyl)-2h-1-benzopyran-7-ol

18. Ccris 9222

19. 7,4'-isoflavandiol

20. Einecs 208-522-2

21. Equol, (-)-

22. Unii-2t6d2hpx7q

23. Aus-131

24. (?)-equol

25. (3s)-equol

26. Equol [inci]

27. Equol (s)-form

28. Equol [mi]

29. Se 5oh

30. Schembl43647

31. Bidd:er0148

32. Equol, (s)-

33. Dtxsid0022309

34. (3s)-3-(4-hydroxyphenyl)-3,4-dihydro-2h-chromen-7-ol

35. Aus 131

36. 3,4-dihydro-3-(4-hydroxyphenyl)-(s)-2h-1-benzopyran-7-ol

37. S-equol, >=97% (hplc)

38. Zinc388661

39. Act03253

40. Bcp13598

41. Ex-a1354

42. Bdbm50410528

43. Mfcd00200962

44. S2450

45. Akos016842347

46. Ccg-266891

47. Cs-7937

48. Db11674

49. (3s)-3-(4-hydroxyphenyl)-7-chromanol

50. Ncgc00386208-01

51. Ac-34078

52. As-71147

53. (s) -3- (4-hydroxyphenyl) Chroman-7-ol

54. Hy-100583

55. Sw219593-1

56. F17393

57. 531d953

58. A829437

59. Q5384747

2.4 Create Date
2005-07-09
3 Chemical and Physical Properties
Molecular Weight 242.27 g/mol
Molecular Formula C15H14O3
XLogP33
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area49.7
Heavy Atom Count18
Formal Charge0
Complexity273
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Phytoestrogens

Compounds derived from plants, primarily ISOFLAVONES that mimic or modulate endogenous estrogens, usually by binding to ESTROGEN RECEPTORS. (See all compounds classified as Phytoestrogens.)


ABOUT THIS PAGE

S-Equol Manufacturers

A S-Equol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of S-Equol, including repackagers and relabelers. The FDA regulates S-Equol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. S-Equol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of S-Equol manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

S-Equol Suppliers

A S-Equol supplier is an individual or a company that provides S-Equol active pharmaceutical ingredient (API) or S-Equol finished formulations upon request. The S-Equol suppliers may include S-Equol API manufacturers, exporters, distributors and traders.

click here to find a list of S-Equol suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

S-Equol GMP

S-Equol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of S-Equol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right S-Equol GMP manufacturer or S-Equol GMP API supplier for your needs.

S-Equol CoA

A S-Equol CoA (Certificate of Analysis) is a formal document that attests to S-Equol's compliance with S-Equol specifications and serves as a tool for batch-level quality control.

S-Equol CoA mostly includes findings from lab analyses of a specific batch. For each S-Equol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

S-Equol may be tested according to a variety of international standards, such as European Pharmacopoeia (S-Equol EP), S-Equol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (S-Equol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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