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    Chemistry

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    Also known as: Sacubitril sodium, 149690-05-1, Ahu-377 sodium, Sacubitril (sodium), Mop72gep8z, Sodium;4-[[(2s,4r)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate
    Molecular Formula
    C24H28NNaO5
    Molecular Weight
    433.5  g/mol
    InChI Key
    RRTBVEJIZWGATF-JKSHRDEXSA-M
    FDA UNII
    MOP72GEP8Z
    Sacubitril Sodium
    1 2D Structure

    Sacubitril Sodium

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate
    2.1.2 InChI
    InChI=1S/C24H29NO5.Na/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19;/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28);/q;+1/p-1/t17-,21+;/m1./s1
    2.1.3 InChI Key
    RRTBVEJIZWGATF-JKSHRDEXSA-M
    2.1.4 Canonical SMILES
    CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)[O-].[Na+]
    2.1.5 Isomeric SMILES
    CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)[O-].[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    MOP72GEP8Z
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. Sacubitril Sodium

    2. 149690-05-1

    3. Ahu-377 Sodium

    4. Sacubitril (sodium)

    5. Mop72gep8z

    6. Sodium;4-[[(2s,4r)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate

    7. Unii-mop72gep8z

    8. Sacubitril Sodium Salt

    9. Sacubitril Sodium [mi]

    10. Schembl21239956

    11. Dtxsid90164362

    12. Hy-15407b

    13. (1,1'-biphenyl)-4-pentanoic Acid, Gamma-((3-carboxy-1-oxopropyl)amino)-alpha-methyl-, 4-ethyl Ester, Sodium Salt (1:1), (alphar,gammas)-

    14. Cs-0079358

    15. A937423

    16. Q27284149

    17. (1,1'-biphenyl)-4-pentanoic Acid, .gamma.-((3-carboxy-1-oxopropyl)amino)-.alpha.-methyl-, 4-ethyl Ester, Sodium Salt (1:1), (.alpha.r,.gamma.s)-

    18. Sodium 4-(((2s,4r)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate

    2.4 Create Date
    2008-02-05
    3 Chemical and Physical Properties
    Molecular Weight 433.5 g/mol
    Molecular Formula C24H28NNaO5
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count12
    Exact Mass433.18651728 g/mol
    Monoisotopic Mass433.18651728 g/mol
    Topological Polar Surface Area95.5 Ų
    Heavy Atom Count31
    Formal Charge0
    Complexity556
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2

    API Reference Price

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    04-Feb-2021
    28-Mar-2025
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    ABOUT THIS PAGE

    Looking for 149690-05-1 / Sacubitril Sodium API manufacturers, exporters & distributors?

    Sacubitril Sodium manufacturers, exporters & distributors 1

    32

    PharmaCompass offers a list of Sacubitril Sodium API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Sacubitril Sodium manufacturer or Sacubitril Sodium supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Sacubitril Sodium manufacturer or Sacubitril Sodium supplier.

    PharmaCompass also assists you with knowing the Sacubitril Sodium API Price utilized in the formulation of products. Sacubitril Sodium API Price is not always fixed or binding as the Sacubitril Sodium Price is obtained through a variety of data sources. The Sacubitril Sodium Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Sacubitril Sodium

    Synonyms

    149690-05-1, Ahu-377 sodium, Sacubitril (sodium), Mop72gep8z, Sodium;4-[[(2s,4r)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate, Unii-mop72gep8z

    Cas Number

    149690-05-1

    Unique Ingredient Identifier (UNII)

    MOP72GEP8Z

    Sacubitril Manufacturers

    A Sacubitril manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sacubitril, including repackagers and relabelers. The FDA regulates Sacubitril manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sacubitril API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Sacubitril manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Sacubitril Suppliers

    A Sacubitril supplier is an individual or a company that provides Sacubitril active pharmaceutical ingredient (API) or Sacubitril finished formulations upon request. The Sacubitril suppliers may include Sacubitril API manufacturers, exporters, distributors and traders.

    click here to find a list of Sacubitril suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Sacubitril USDMF

    A Sacubitril DMF (Drug Master File) is a document detailing the whole manufacturing process of Sacubitril active pharmaceutical ingredient (API) in detail. Different forms of Sacubitril DMFs exist exist since differing nations have different regulations, such as Sacubitril USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Sacubitril DMF submitted to regulatory agencies in the US is known as a USDMF. Sacubitril USDMF includes data on Sacubitril's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Sacubitril USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Sacubitril suppliers with USDMF on PharmaCompass.

    Sacubitril WC

    A Sacubitril written confirmation (Sacubitril WC) is an official document issued by a regulatory agency to a Sacubitril manufacturer, verifying that the manufacturing facility of a Sacubitril active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Sacubitril APIs or Sacubitril finished pharmaceutical products to another nation, regulatory agencies frequently require a Sacubitril WC (written confirmation) as part of the regulatory process.

    click here to find a list of Sacubitril suppliers with Written Confirmation (WC) on PharmaCompass.

    Sacubitril NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Sacubitril as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Sacubitril API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Sacubitril as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Sacubitril and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Sacubitril NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Sacubitril suppliers with NDC on PharmaCompass.

    Sacubitril GMP

    Sacubitril Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Sacubitril GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sacubitril GMP manufacturer or Sacubitril GMP API supplier for your needs.

    Sacubitril CoA

    A Sacubitril CoA (Certificate of Analysis) is a formal document that attests to Sacubitril's compliance with Sacubitril specifications and serves as a tool for batch-level quality control.

    Sacubitril CoA mostly includes findings from lab analyses of a specific batch. For each Sacubitril CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Sacubitril may be tested according to a variety of international standards, such as European Pharmacopoeia (Sacubitril EP), Sacubitril JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sacubitril USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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