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    Chemistry

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    Also known as: Sacubitril sodium, 149690-05-1, Ahu-377 sodium, Sacubitril (sodium), Mop72gep8z, Sodium;4-[[(2s,4r)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate
    Molecular Formula
    C24H28NNaO5
    Molecular Weight
    433.5  g/mol
    InChI Key
    RRTBVEJIZWGATF-JKSHRDEXSA-M
    FDA UNII
    MOP72GEP8Z
    Sacubitril Sodium
    1 2D Structure

    Sacubitril Sodium

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate
    2.1.2 InChI
    InChI=1S/C24H29NO5.Na/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19;/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28);/q;+1/p-1/t17-,21+;/m1./s1
    2.1.3 InChI Key
    RRTBVEJIZWGATF-JKSHRDEXSA-M
    2.1.4 Canonical SMILES
    CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)[O-].[Na+]
    2.1.5 Isomeric SMILES
    CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)[O-].[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    MOP72GEP8Z
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. Sacubitril Sodium

    2. 149690-05-1

    3. Ahu-377 Sodium

    4. Sacubitril (sodium)

    5. Mop72gep8z

    6. Sodium;4-[[(2s,4r)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate

    7. Unii-mop72gep8z

    8. Sacubitril Sodium Salt

    9. Sacubitril Sodium [mi]

    10. Schembl21239956

    11. Dtxsid90164362

    12. Hy-15407b

    13. (1,1'-biphenyl)-4-pentanoic Acid, Gamma-((3-carboxy-1-oxopropyl)amino)-alpha-methyl-, 4-ethyl Ester, Sodium Salt (1:1), (alphar,gammas)-

    14. Cs-0079358

    15. A937423

    16. Q27284149

    17. (1,1'-biphenyl)-4-pentanoic Acid, .gamma.-((3-carboxy-1-oxopropyl)amino)-.alpha.-methyl-, 4-ethyl Ester, Sodium Salt (1:1), (.alpha.r,.gamma.s)-

    18. Sodium 4-(((2s,4r)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate

    2.4 Create Date
    2008-02-05
    3 Chemical and Physical Properties
    Molecular Weight 433.5 g/mol
    Molecular Formula C24H28NNaO5
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count12
    Exact Mass433.18651728 g/mol
    Monoisotopic Mass433.18651728 g/mol
    Topological Polar Surface Area95.5 Ų
    Heavy Atom Count31
    Formal Charge0
    Complexity556
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2

    API Reference Price

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REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"2.10","actualQuantity":"2.1","unit":"KGS","unitRateFc":"800","totalValueFC":"1700.1","currency":"USD","unitRateINR":"67480","date":"03-May-2024","totalValueINR":"141708","totalValueInUsd":"1700.1","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"3308461","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"NO.518, LAO DONG EAST ROAD, CHANGZHOU JIANGSU 213018, CHINA. Changzhou, , China China","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717180200,"product":"SACUBITRIL CALCIUM","address":"48, KANDIVLI INDUSTRIAL ESTATE,","city":"MUMBAI, MAHARASHTRA.","supplier":"SIHUAN PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"IPCA LABORATORIES","customerCountry":"INDIA","quantity":"400.50","actualQuantity":"400.5","unit":"KGS","unitRateFc":"360","totalValueFC":"145683.6","currency":"USD","unitRateINR":"30366","date":"01-Jun-2024","totalValueINR":"12161583","totalValueInUsd":"145683.6","indian_port":"Bombay Air","hs_no":"29189990","bill_no":"3778018","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"EAST ZONE OF ECONOMIC DEVELOPMENT ZONE, PINGYUAN COUNTY, DEZHOU CITY,Shandong - 253100, , China China","customerAddress":"48, KANDIVLI INDUSTRIAL ESTATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723141800,"product":"SACUBITRIL VALSARTAN NA HYDRATE\/DS11","address":"SANDOZ HOUSE,8TH FLOOR,","city":"MUMBAI,MAHARASHTRA","supplier":"NOVARTIS PHARMACEUTICALS CORPORATION","supplierCountry":"SWITZERLAND","foreign_port":"BASLE","customer":"NOVARTIS PHARMACEUTICALS CORPORATION","customerCountry":"INDIA","quantity":"35.00","actualQuantity":"35000","unit":"GMS","unitRateFc":"2.3","totalValueFC":"95645.7","currency":"CHF","unitRateINR":"229.2","date":"09-Aug-2024","totalValueINR":"8022618.52","totalValueInUsd":"95645.7","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"4975785","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"BASLE","supplierAddress":"LICHSTRASE 35CH-4002 BASELSWITZERLAND CH","customerAddress":"SANDOZ HOUSE,8TH FLOOR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731349800,"product":"SACUBITRIL -VALSARTAN TRISODIUM (AMORPHOUS) IHS (D90 NMT 65MICRON) (DMF GRADE -MACLEODS) BATCH NO. E\/1236\/A22001SACUBITRIL -VALSARTAN TRISODIUM (AMORPHOUS) IHS (D90 NMT 65","address":"304,ATLANTA ARCADE,","city":"MUMBAI MAHARASHTRA","supplier":"MACLEODS PHARMACEUTICAL LTD.","supplierCountry":"INDIA","foreign_port":"INDORE(EPZ\/SEZ)","customer":"MACLEODS PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"17.26","actualQuantity":"17.258","unit":"KGS","unitRateFc":"551.7","totalValueFC":"9612.8","currency":"USD","unitRateINR":"47004.7","date":"12-Nov-2024","totalValueINR":"811207","totalValueInUsd":"9612.8","indian_port":"Indore-EPZ\/SEZ","hs_no":"29339990","bill_no":"6636885","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"INDORE(EPZ\/SEZ)","supplierAddress":"PLOT NO. M-50 TO 54&54A, PHASE-II, INDORE SPECIAL ECONOMIC ZONE, PITHAMPUR, DIST. DHAR INDIA","customerAddress":"304,ATLANTA ARCADE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731695400,"product":"SACUBITRIL SODIUM (TEST LIC NO-SW\/OD\/11\/2024\/000005897 DT-25\/09\/2024)","address":"304,MOHAN PLACE,L.S.C.BLOCK-C","city":"DELHI","supplier":"ZHEJIANG TIANYU PHARMACEUTICAL CO., LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"AKUMS DRUGS & PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"24.00","actualQuantity":"24","unit":"KGS","unitRateFc":"600","totalValueFC":"14555.6","currency":"USD","unitRateINR":"51180","date":"16-Nov-2024","totalValueINR":"1228320","totalValueInUsd":"14555.6","indian_port":"Delhi Air","hs_no":"29411090","bill_no":"6721211","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"JIANGKOU DEVELOPMENT ZONE HUANGYAN TAIZHOU ZHEJIANG ZHEJIANG, , CHINA SDNF CHINA","customerAddress":"304,MOHAN PLACE,L.S.C.BLOCK-C"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1736274600,"product":"SACUBITRIL CALCIUM 20","address":"7.1.77\/E\/1\/303, DHARAM KARAM ROAD","city":"HYDERABAD,A.P.","supplier":"ZHEJIANG RAYBOW PHARMA","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"DIVI'S LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"5247.66","actualQuantity":"5247.66","unit":"KGS","unitRateFc":"529.3","totalValueFC":"2789530.6","currency":"USD","unitRateINR":"45837.4","date":"08-Jan-2025","totalValueINR":"240538985.53","totalValueInUsd":"2789530.6","indian_port":"Vizag-DLL SEZ","hs_no":"29339990","bill_no":"7674474","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO.18 NANYANGSAN ROAD ,DUQIAO LINHAI NANYANG SAN RD,TAIZHOU CITY SDNF China","customerAddress":"7.1.77\/E\/1\/303, DHARAM KARAM ROAD"}]
    03-Feb-2021
    20-Jan-2025
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    ABOUT THIS PAGE

    Looking for 149690-05-1 / Sacubitril Sodium API manufacturers, exporters & distributors?

    Sacubitril Sodium manufacturers, exporters & distributors 1

    32

    PharmaCompass offers a list of Sacubitril Sodium API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Sacubitril Sodium manufacturer or Sacubitril Sodium supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Sacubitril Sodium manufacturer or Sacubitril Sodium supplier.

    PharmaCompass also assists you with knowing the Sacubitril Sodium API Price utilized in the formulation of products. Sacubitril Sodium API Price is not always fixed or binding as the Sacubitril Sodium Price is obtained through a variety of data sources. The Sacubitril Sodium Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Sacubitril Sodium

    Synonyms

    149690-05-1, Ahu-377 sodium, Sacubitril (sodium), Mop72gep8z, Sodium;4-[[(2s,4r)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate, Unii-mop72gep8z

    Cas Number

    149690-05-1

    Unique Ingredient Identifier (UNII)

    MOP72GEP8Z

    Sacubitril Sodium Manufacturers

    A Sacubitril Sodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sacubitril Sodium, including repackagers and relabelers. The FDA regulates Sacubitril Sodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sacubitril Sodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Sacubitril Sodium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Sacubitril Sodium Suppliers

    A Sacubitril Sodium supplier is an individual or a company that provides Sacubitril Sodium active pharmaceutical ingredient (API) or Sacubitril Sodium finished formulations upon request. The Sacubitril Sodium suppliers may include Sacubitril Sodium API manufacturers, exporters, distributors and traders.

    click here to find a list of Sacubitril Sodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Sacubitril Sodium USDMF

    A Sacubitril Sodium DMF (Drug Master File) is a document detailing the whole manufacturing process of Sacubitril Sodium active pharmaceutical ingredient (API) in detail. Different forms of Sacubitril Sodium DMFs exist exist since differing nations have different regulations, such as Sacubitril Sodium USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Sacubitril Sodium DMF submitted to regulatory agencies in the US is known as a USDMF. Sacubitril Sodium USDMF includes data on Sacubitril Sodium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Sacubitril Sodium USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Sacubitril Sodium suppliers with USDMF on PharmaCompass.

    Sacubitril Sodium WC

    A Sacubitril Sodium written confirmation (Sacubitril Sodium WC) is an official document issued by a regulatory agency to a Sacubitril Sodium manufacturer, verifying that the manufacturing facility of a Sacubitril Sodium active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Sacubitril Sodium APIs or Sacubitril Sodium finished pharmaceutical products to another nation, regulatory agencies frequently require a Sacubitril Sodium WC (written confirmation) as part of the regulatory process.

    click here to find a list of Sacubitril Sodium suppliers with Written Confirmation (WC) on PharmaCompass.

    Sacubitril Sodium NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Sacubitril Sodium as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Sacubitril Sodium API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Sacubitril Sodium as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Sacubitril Sodium and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Sacubitril Sodium NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Sacubitril Sodium suppliers with NDC on PharmaCompass.

    Sacubitril Sodium GMP

    Sacubitril Sodium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Sacubitril Sodium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sacubitril Sodium GMP manufacturer or Sacubitril Sodium GMP API supplier for your needs.

    Sacubitril Sodium CoA

    A Sacubitril Sodium CoA (Certificate of Analysis) is a formal document that attests to Sacubitril Sodium's compliance with Sacubitril Sodium specifications and serves as a tool for batch-level quality control.

    Sacubitril Sodium CoA mostly includes findings from lab analyses of a specific batch. For each Sacubitril Sodium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Sacubitril Sodium may be tested according to a variety of international standards, such as European Pharmacopoeia (Sacubitril Sodium EP), Sacubitril Sodium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sacubitril Sodium USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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