List of Related Excipient Companies and Suppliers of Safinamide Mesylate by Ideal Cures Pvt Ltd on PharmaCompass.com

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Chemistry

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Also known as: 202825-46-5, Safinamide mesilate, (s)-2-((4-((3-fluorobenzyl)oxy)benzyl)amino)propanamide methanesulfonate, Pnu-151774e, Nw-1015, Safinamide (mesylate)
Molecular Formula
C18H23FN2O5S
Molecular Weight
398.5  g/mol
InChI Key
YKOCHIUQOBQIAC-YDALLXLXSA-N
FDA UNII
YS90V3DTX0

Safinamide Mesylate
1 2D Structure

Safinamide Mesylate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide;methanesulfonic acid
2.1.2 InChI
InChI=1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1
2.1.3 InChI Key
YKOCHIUQOBQIAC-YDALLXLXSA-N
2.1.4 Canonical SMILES
CC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O
2.1.5 Isomeric SMILES
C[C@@H](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O
2.2 Other Identifiers
2.2.1 UNII
YS90V3DTX0
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (s)-2-((4-(3-fluorobenzoxy)benzyl)amino)propanamide

2. 2-(4-(3-fluorobenzyloxy)benzylamino)propionamide

3. Fbap Methanesulfonate

4. Fce 26743

5. Fce 28073

6. Fce-26743

7. Fce-28073

8. Nw-1015

9. Pnu 151774e

10. Pnu-151774e

11. Safinamide

12. Safinamide Methanesulfonate

13. Xadago

2.3.2 Depositor-Supplied Synonyms

1. 202825-46-5

2. Safinamide Mesilate

3. (s)-2-((4-((3-fluorobenzyl)oxy)benzyl)amino)propanamide Methanesulfonate

4. Pnu-151774e

5. Nw-1015

6. Safinamide (mesylate)

7. Safinamide Methanesulfonate

8. Pnu 151774e

9. Safinamide Mesylate [usan]

10. Fce-28073

11. Nw 1015

12. Safinamide Methansulfonate

13. Ys90v3dtx0

14. Propanamide, 2-[[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]amino]-, (2s)-, Methanesulfonate (1:1)

15. 202825-46-5 (mesylate)

16. Safinamide Mesilate (jan)

17. Safinamide Mesylate (usan)

18. Safinamide Mesilate [jan]

19. (s)-2-((4-((3-fluorobenzyl)oxy)benzyl)-amino)propanamide Methanesulfonate

20. Chembl48582

21. (s)-2-[[4-[(3-fluorobenzyl)oxy]benzyl]amino]propanamide Methanesulfonate

22. Unii-ys90v3dtx0

23. Fce-28073(r-isomer)

24. Safinamidemesylate

25. Equfina (tn)

26. Xadago (tn)

27. Safinamide Mesylate Salt

28. Emd 1195686 Mesylate

29. Mls006010740

30. Schembl1665715

31. Dtxsid80942414

32. Hms3884o17

33. Safinamide Mesylate (fce28073)

34. Amy38833

35. Bcp16018

36. Ex-a2640

37. Hy-70057a

38. Mfcd15145475

39. S1472

40. Safinamide Mesilate [who-dd]

41. Akos015902297

42. Ccg-268636

43. Safinamide Methanesulfonate [mi]

44. Safinamide Mesylate [orange Book]

45. Ac-27739

46. As-75602

47. Pnu-151774e,fce28073

48. Smr004701699

49. Safinamide Mesylate Salt, >=98% (hplc)

50. Cs-0006742

51. Sw219452-1

52. D10191

53. J-013174

54. Q27294690

55. (s)-2[4-(3-fluorobenzyloxy)benzylamino]propanamide Methanesulfonate

56. (s)-(+)-2-(4-(3-fluorobenzyloxy) Benzylamino)propanamide, Methanesulfonate

57. (s)-2-((4-((3-fluorobenzyl)oxy)benzyl)amino)propanamidemethanesulfonate

58. (s)-2-[4-(3-fluorobenzyloxy)benzylamino]propanamide Methanesulfonate

59. (2s)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide;methanesulfonic Acid

60. Propanamide, 2-(((4-((3-fluorophenyl)methoxy)phenyl)methyl)amino)-, (s)-, Monomethanesulfonate

2.4 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 398.5 g/mol
Molecular Formula C18H23FN2O5S
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Exact Mass398.13117117 g/mol
Monoisotopic Mass398.13117117 g/mol
Topological Polar Surface Area127 Ų
Heavy Atom Count27
Formal Charge0
Complexity438
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Indication

Xadago is indicated for the treatment of adult patients with idiopathic Parkinsons disease (PD) as add-on therapy to a stable dose of Levodopa (L-dopa) alone or in combination with other PD medicinal products in mid-to late-stage fluctuating patients.


5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Pharmacological Classes
Monoamine Oxidase Type B Inhibitor [EPC]; Monoamine Oxidase-B Inhibitors [MoA]; Breast Cancer Resistance Protein Inhibitors [MoA]
5.2 ATC Code

N04B


API SUPPLIERS

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Polpharma

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Biophore India Pharmaceuticals Pvt...

India

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LGM Pharma

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Metrochem API Private Limited

India

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Suanfarma

Spain

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ZACH System SA

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HRV Global Life Sciences

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Optimus Pharma

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Solara Active Pharma Sciences

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Zhejiang Huahai Pharmaceutical

China

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API Reference Price

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AP","supplier":"OPTIMUS DRUGS PRIVATE ","supplierCountry":"INDIA","foreign_port":"ISTANBUL","customer":"TO THE ORDER OF","customerCountry":"TURKEY","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"1800","totalValueFC":"5300.7","currency":"USD","unitRateINR":146666.66666666666,"date":"04-Sep-2023","totalValueINR":"440000","totalValueInUsd":"5300.7","indian_port":"Hyderabad Air","hs_no":"29242990","bill_no":"3702690","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"TURKEY","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"PLOT NO.131,3RD FLOOR,NARMADA, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1673548200,"product":"SAFINAMIDE MESYLATE","address":"SURVEY NO 91 OPP NAVIN FLOURINE,IN D UDHNA NAVSARI ROAD BHESTAN","city":"SURAT,GUJARAT","supplier":"ZHEJIANG HUAHAI PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"NA","customer":"CTX LIFESCIENCES","customerCountry":"INDIA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"2000","totalValueFC":"6142.4","currency":"USD","unitRateINR":"167400","date":"13-Jan-2023","totalValueINR":"502200","totalValueInUsd":"6142.4","indian_port":"BOMBAY AIR","hs_no":"29242990","bill_no":"4173726","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SURVEY NO 91 OPP NAVIN FLOURINE,IN D UDHNA NAVSARI ROAD BHESTAN"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723833000,"product":"SAFINAMIDE MESYLATE. B\/N: D5431-22-004. MFG. DT. 08\/05\/2022RETEST DT. 04\/2026","address":"PLOT NO.5222, PHASE- IV,","city":"AHMEDABAD -","supplier":"ZHEJIANG HUAHAI PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"UNISON PHARMACEUTICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"1200","totalValueFC":"6069.5","currency":"USD","unitRateINR":"101820","date":"17-Aug-2024","totalValueINR":"509100","totalValueInUsd":"6069.5","indian_port":"Ahmedabad Air","hs_no":"29242990","bill_no":"5111789","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"XUNQIAO,LINHAI ,ZHEJIANG 317024 CHISDNF CHINA","customerAddress":"PLOT NO.5222, PHASE- IV,"}]
20-Apr-2021
17-Aug-2024
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