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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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API Suppliers

API Suppliers

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

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EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

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API REF. PRICE (USD/KG)

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FDF

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Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

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DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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JP

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Data Compilation #PharmaFlow

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GLOBAL SALES INFORMATION

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Chemistry

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Also known as: 138-52-3, Salicoside, Salicine, D-(-)-salicin, Salicyl alcohol glucoside, D(-)-salicin
Molecular Formula
C13H18O7
Molecular Weight
286.28  g/mol
InChI Key
NGFMICBWJRZIBI-UJPOAAIJSA-N
FDA UNII
4649620TBZ

Salicin
salicin is a natural product found in Salix atrocinerea, Salix candida, and other organisms with data available.
1 2D Structure

Salicin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triol
2.1.2 InChI
InChI=1S/C13H18O7/c14-5-7-3-1-2-4-8(7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1
2.1.3 InChI Key
NGFMICBWJRZIBI-UJPOAAIJSA-N
2.1.4 Canonical SMILES
C1=CC=C(C(=C1)CO)OC2C(C(C(C(O2)CO)O)O)O
2.1.5 Isomeric SMILES
C1=CC=C(C(=C1)CO)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O
2.2 Other Identifiers
2.2.1 UNII
4649620TBZ
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Salicyl Alcohol Glucoside

2.3.2 Depositor-Supplied Synonyms

1. 138-52-3

2. Salicoside

3. Salicine

4. D-(-)-salicin

5. Salicyl Alcohol Glucoside

6. D(-)-salicin

7. (2r,3s,4s,5r,6s)-2-(hydroxymethyl)-6-(2-(hydroxymethyl)phenoxy)tetrahydro-2h-pyran-3,4,5-triol

8. 2-(hydroxymethyl)phenyl Beta-d-glucopyranoside

9. Saligenin Beta-d-glucopyranoside

10. Saligenin-beta-d-glucopyranoside

11. D-salicin

12. Alpha-hydroxy-o-tolyl Beta-d-glucopyranoside

13. Salicinum

14. 2-(hydroxymethyl)phenyl-beta-d-glucopyranoside

15. Nsc 5751

16. O-(hydroxymethyl)phenyl Beta-d-glucopyranoside

17. Beta-d-glucopyranoside, 2-(hydroxymethyl)phenyl

18. Benzyl Alcohol, O-hydroxy-, O-glucoside

19. Ai3-19099

20. Spectrum1502255

21. B-d-glucopyranoside, 2-(hydroxymethyl)phenyl

22. Chebi:17814

23. Nsc-5751

24. D-()-salicin

25. (2r,3s,4s,5r,6s)-2-(hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triol

26. 4649620tbz

27. Sdccgmls-0066698.p001

28. Ncgc00142605-01

29. Mfcd00006590

30. (2r,3s,4s,5r,6s)-2-(hydroxymethyl)-6-(2-(hydroxymethyl)-phenoxy)tetrahydro-2h-pyran-3,4,5-triol

31. Smr000112301

32. Salicin [usp]

33. Sr-05000001594

34. Salicin (6ci,8ci)

35. Einecs 205-331-6

36. Delta-salicin

37. Unii-4649620tbz

38. 2-(hydroxymethyl)phenyl Hexopyranoside

39. Saligenin Glucoside

40. Sa0

41. D-(?)-salicin

42. Spectrum_001230

43. 2-(hydroxymethyl)phenyl-.beta.-d-glucopyranoside

44. Salicin [inci]

45. Salicin [mi]

46. Salicinum [hpus]

47. Spectrum2_000756

48. Spectrum3_000948

49. Spectrum4_001058

50. Spectrum5_000971

51. Bmse000315

52. Salicyl Alcohol-b-glucoside

53. Saligenin Bet.-d-glucoside

54. D-salicin [usp-rs]

55. Schembl24936

56. Kbiogr_001356

57. Kbioss_001710

58. Saligenin-b-d-glucopyranoside

59. Mls000563050

60. Mls001306490

61. Divk1c_000030

62. S0625_sigma

63. Spbio_000772

64. Chembl462997

65. Megxp0_000685

66. Salicin (salicoside, Salicine)

67. Acon1_000373

68. Hms500b12

69. Kbio1_000030

70. Kbio2_001710

71. Kbio2_004278

72. Kbio2_006846

73. Kbio3_002016

74. Dtxsid10883326

75. Ninds_000030

76. Hms1921p08

77. Hms2092f14

78. Hms2268j11

79. Hms3884b15

80. Pharmakon1600-01502255

81. Hy-n0149

82. Saligenin Beta-delta-glucopyranoside

83. Saligenin-beta-delta-glucopyranoside

84. Zinc3847505

85. D-(-)-salicin, Analytical Standard

86. Ccg-40332

87. Nsc758201

88. S2351

89. Zinc03847505

90. Akos004907439

91. Ac-8042

92. Cs-8027

93. D-(-)-salicin, >=99% (gc)

94. Nsc-758201

95. Idi1_000030

96. Ncgc00142605-02

97. Ncgc00142605-04

98. (2s,4s,5s,3r,6r)-6-(hydroxymethyl)-2-[2-(hydroxymethyl)phenoxy]-2h-3,4,5,6-tet Rahydropyran-3,4,5-triol

99. Salicyl Alcohol Glucoside [who-dd]

100. Sbi-0051746.p002

101. 2(hydroxymethyl)phenyl-beta-d-glucopyranoside

102. N1880

103. S0003

104. Sw219123-1

105. C01451

106. 2-(hydroxymethyl)-phenyl-beta-d-glucopyranoside

107. 2-(hydroxymethyl)phenyl-&beta-d-glucopyranoside

108. 2-(hydroxymethyl)phenyl-o-beta-d-glucopyranoside

109. Ab00052296_07

110. 138s523

111. Q419173

112. Sr-05000001594-1

113. Sr-05000001594-2

114. Brd-k64614248-001-02-4

115. Brd-k64614248-001-06-5

116. Ead32be1-198e-432c-9f44-dc0dc9a3305b

117. Salicin, European Pharmacopoeia (ep) Reference Standard

118. D-salicin, United States Pharmacopeia (usp) Reference Standard

119. Wurcs=2.0/1,1,0/[a2122h-1b_1-5_1*o(c^zc^zc^zc^zc^zc^e$3)/4co]/1/

120. 2-(hydroxymethyl)phenyl-beta-d-glucopyranoside, Salicoside, Salicyl Alcohol Glucoside, Saligenin Beta-d-glucoside

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 286.28 g/mol
Molecular Formula C13H18O7
XLogP3-1.2
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass286.10525291 g/mol
Monoisotopic Mass286.10525291 g/mol
Topological Polar Surface Area120 Ų
Heavy Atom Count20
Formal Charge0
Complexity300
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Cyclooxygenase Inhibitors

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)


REF. STANDARDS & IMPURITIES

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ABOUT THIS PAGE

Salicin Manufacturers

A Salicin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Salicin, including repackagers and relabelers. The FDA regulates Salicin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Salicin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Salicin Suppliers

A Salicin supplier is an individual or a company that provides Salicin active pharmaceutical ingredient (API) or Salicin finished formulations upon request. The Salicin suppliers may include Salicin API manufacturers, exporters, distributors and traders.

Salicin GMP

Salicin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Salicin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Salicin GMP manufacturer or Salicin GMP API supplier for your needs.

Salicin CoA

A Salicin CoA (Certificate of Analysis) is a formal document that attests to Salicin's compliance with Salicin specifications and serves as a tool for batch-level quality control.

Salicin CoA mostly includes findings from lab analyses of a specific batch. For each Salicin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Salicin may be tested according to a variety of international standards, such as European Pharmacopoeia (Salicin EP), Salicin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Salicin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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