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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

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Listed Suppliers

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API REF. PRICE (USD/KG)

MARKET PLACE

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

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Listed Dossiers

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FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Data Compilation #PharmaFlow

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GLOBAL SALES INFORMATION

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0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 808-26-4, Bonomycin, Norcycline, 6-demethyl-6-deoxytetracycline, Sancyclinum, Sancycline free base
Molecular Formula
C21H22N2O7
Molecular Weight
414.4  g/mol
InChI Key
MTCQOMXDZUULRV-ADOAZJKMSA-N
FDA UNII
ODN00F2SJG

Sancycline
1 2D Structure

Sancycline

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
2.1.2 InChI
InChI=1S/C21H22N2O7/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29/h3-5,9-10,15,24-25,28,30H,6-7H2,1-2H3,(H2,22,29)/t9-,10-,15-,21-/m0/s1
2.1.3 InChI Key
MTCQOMXDZUULRV-ADOAZJKMSA-N
2.1.4 Canonical SMILES
CN(C)C1C2CC3CC4=C(C(=CC=C4)O)C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O
2.1.5 Isomeric SMILES
CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C(=CC=C4)O)C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O
2.2 Other Identifiers
2.2.1 UNII
ODN00F2SJG
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 6-demethyl-6-desoxytetracycline

2. 6-deoxy-6-demethyltetracycline

3. 6-desoxy-6-demethyltetracyclin

4. 6-dodmtc

5. Bonomycin

6. Sancycline Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 808-26-4

2. Bonomycin

3. Norcycline

4. 6-demethyl-6-deoxytetracycline

5. Sancyclinum

6. Sancycline Free Base

7. Gs 2147

8. Odn00f2sjg

9. Gs-2147

10. 808-26-4 (free Base)

11. 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide

12. Sanciclina

13. (4s,4as,5ar,12ar)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide

14. (4s,4as,5ar,12as)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide

15. (4s,4as,5ar,12as)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

16. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4s,4as,5ar,12as)-

17. Nsc51812

18. Sancycline [usan:inn]

19. Sancyclinum [inn-latin]

20. Unii-odn00f2sjg

21. Sanciclina [inn-spanish]

22. Nsc 51812 (as Hydrochloride)

23. Bonomycin (tn)

24. Sancycline [mi]

25. Sancycline [inn]

26. Sancycline (usan/inn)

27. Sancycline [usan]

28. Dsstox_cid_31625

29. Dsstox_rid_97509

30. Dsstox_gsid_57836

31. Schembl112644

32. Schembl1649653

33. Chembl2009312

34. Dtxsid5057836

35. Schembl23271182

36. Ex-a210

37. Chebi:135671

38. Tox21_113907

39. S5859

40. Zinc22066481

41. Akos022186417

42. Akos037517260

43. Zinc103941901

44. Cs-5602

45. Bonomycin;6-demethyl-6-deoxytetracycline

46. Ncgc00262909-01

47. 4beta-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12abeta-tetrahydroxy-1,11-dioxo-2-naphthacencarboxamid

48. Bs-22405

49. Cas-808-26-4

50. Hy-17466

51. Nci60_004256

52. D05796

53. 808s264

54. A864642

55. Q27285586

56. (4s,4as,12as)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

57. (4s,4as,5ar,12as)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-naphthacenecarboxamide

58. (4s,4as,5ar,12as)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide

59. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4s-(4alpha,4aalpha,5aalpha,12aalpha))-

60. 4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-napththacenecarboxamide, Hydrochloride

2.4 Create Date
2011-12-26
3 Chemical and Physical Properties
Molecular Weight 414.4 g/mol
Molecular Formula C21H22N2O7
XLogP31.2
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count2
Exact Mass414.14270105 g/mol
Monoisotopic Mass414.14270105 g/mol
Topological Polar Surface Area161 Ų
Heavy Atom Count30
Formal Charge0
Complexity892
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API SUPPLIERS

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API Reference Price

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02-Jan-2024
02-Jan-2024
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ABOUT THIS PAGE

Sancycline Manufacturers

A Sancycline manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sancycline, including repackagers and relabelers. The FDA regulates Sancycline manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sancycline API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sancycline Suppliers

A Sancycline supplier is an individual or a company that provides Sancycline active pharmaceutical ingredient (API) or Sancycline finished formulations upon request. The Sancycline suppliers may include Sancycline API manufacturers, exporters, distributors and traders.

click here to find a list of Sancycline suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sancycline USDMF

A Sancycline DMF (Drug Master File) is a document detailing the whole manufacturing process of Sancycline active pharmaceutical ingredient (API) in detail. Different forms of Sancycline DMFs exist exist since differing nations have different regulations, such as Sancycline USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Sancycline DMF submitted to regulatory agencies in the US is known as a USDMF. Sancycline USDMF includes data on Sancycline's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Sancycline USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Sancycline suppliers with USDMF on PharmaCompass.

Sancycline GMP

Sancycline Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sancycline GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sancycline GMP manufacturer or Sancycline GMP API supplier for your needs.

Sancycline CoA

A Sancycline CoA (Certificate of Analysis) is a formal document that attests to Sancycline's compliance with Sancycline specifications and serves as a tool for batch-level quality control.

Sancycline CoA mostly includes findings from lab analyses of a specific batch. For each Sancycline CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sancycline may be tested according to a variety of international standards, such as European Pharmacopoeia (Sancycline EP), Sancycline JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sancycline USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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