Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 USDMF

1 API Suppliers
1 USDMF

DEVELOPMENTS

3 Drugs in Development

3 Drugs in Development

DIGITAL CONTENT

1 NEWS #PharmaBuzz

media
1 NEWS #PharmaBuzz

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

3DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Sauzivamycin, Mls002703016, 21090-35-7, Nsc143648, Sangivamycin, hydrochloride, Sangivamycin - hcl

Molecular Formula

C₁₂H₁₆ClN₅O₅

Molecular Weight

345.74 g/mol

InChI Key

WTSGTUMQZSEZIW-UHFFFAOYSA-N

Sangivamycin Hydrochloride is the salt of a deaza-adenosine antibiotic isolated from the bacterium Streptomyces rimosus with potent cytotoxic properties. Sangivamycin inhibits protein kinase C (PKC), a signaling mediator important for cell growth and differentiation. This agent may also interfere with protein synthesis by inhibiting the formation of complexes essential to the initiation of protein synthesis and DNA synthesis. (NCI04)

1 2D Structure

Sangivamycin Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-amino-7-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carboxamide;hydrochloride

2.1.2 InChI

InChI=1S/C12H15N5O5.ClH/c13-9-6-4(10(14)21)1-17(11(6)16-3-15-9)12-8(20)7(19)5(2-18)22-12;/h1,3,5,7-8,12,18-20H,2H2,(H2,14,21)(H2,13,15,16);1H

2.1.3 InChI Key

WTSGTUMQZSEZIW-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1=C(C2=C(N=CN=C2N1C3C(C(C(O3)CO)O)O)N)C(=O)N.Cl

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Sauzivamycin

2. Mls002703016

3. 21090-35-7

4. Nsc143648

5. Sangivamycin, Hydrochloride

6. Sangivamycin - Hcl

7. Chembl1988182

8. Dtxsid20417691

9. Nsc1436468

10. 7h-pyrrolo[2, 4-amino-7-.beta.-d-ribofuranosyl-, Monohydrochloride (mf1)

11. 4-amino-7-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carboxamide;hydrochloride

2.3 Create Date

2006-02-02

3 Chemical and Physical Properties

Molecular Formula	C₁₂H₁₆ClN₅O₅
Molecular Weight	345.74 g/mol
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	3
Exact Mass	345.0839963 g/mol
Monoisotopic Mass	345.0839963 g/mol
Topological Polar Surface Area	170 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	440
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	4
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2