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Chemistry

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Also known as: 495399-09-2, Lipaglyn, Zyh1, Saroglitazar [inn], (s)-2-ethoxy-3-(4-(2-(2-methyl-5-(4-(methylthio)phenyl)-1h-pyrrol-1-yl)ethoxy)phenyl)propanoic acid, E0ymx3s4jd
Molecular Formula
C25H29NO4S
Molecular Weight
439.6  g/mol
InChI Key
MRWFZSLZNUJVQW-DEOSSOPVSA-N
FDA UNII
E0YMX3S4JD

Saroglitazar
Saroglitazar has been investigated for the treatment of Fatty Liver.
1 2D Structure

Saroglitazar

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-ethoxy-3-[4-[2-[2-methyl-5-(4-methylsulfanylphenyl)pyrrol-1-yl]ethoxy]phenyl]propanoic acid
2.1.2 InChI
InChI=1S/C25H29NO4S/c1-4-29-24(25(27)28)17-19-6-10-21(11-7-19)30-16-15-26-18(2)5-14-23(26)20-8-12-22(31-3)13-9-20/h5-14,24H,4,15-17H2,1-3H3,(H,27,28)/t24-/m0/s1
2.1.3 InChI Key
MRWFZSLZNUJVQW-DEOSSOPVSA-N
2.1.4 Canonical SMILES
CCOC(CC1=CC=C(C=C1)OCCN2C(=CC=C2C3=CC=C(C=C3)SC)C)C(=O)O
2.1.5 Isomeric SMILES
CCO[C@@H](CC1=CC=C(C=C1)OCCN2C(=CC=C2C3=CC=C(C=C3)SC)C)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
E0YMX3S4JD
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (2s)-2-ethoxy-3-(4-(2-(2-methyl-5-(4-(methylsulfanyl)phenyl)-1h-pyrrol-1-yl(ethoxy)phenyl)propanoic Acid

2. (2s)-2-ethoxy-3-(4-(2-(2-methyl-5-(4-(methylsulfanyl)phenyl)-1h-pyrrol-1-yl(ethoxy)phenyl)propanoic Acid Magnesium Salt (2:1)

3. Alpha-ethoxy-4-(2-(2-methyl-5-(4-methylthio)phenyl))-1h-pyrrol-1-yl)ethoxy))benzenepropanoic Acid

4. Alpha-ethoxy-4-(2-(2-methyl-5-(4-methylthio)phenyl))-1h-pyrrol-1-yl)ethoxy))benzenepropanoic Acid Magnesium Salt

5. Lipaglyn

6. Saroglitazar Magnesium

7. Zyh1 Compound

2.3.2 Depositor-Supplied Synonyms

1. 495399-09-2

2. Lipaglyn

3. Zyh1

4. Saroglitazar [inn]

5. (s)-2-ethoxy-3-(4-(2-(2-methyl-5-(4-(methylthio)phenyl)-1h-pyrrol-1-yl)ethoxy)phenyl)propanoic Acid

6. E0ymx3s4jd

7. 495399-09-2 (free)

8. (2s)-2-ethoxy-3-[4-[2-[2-methyl-5-(4-methylsulfanylphenyl)pyrrol-1-yl]ethoxy]phenyl]propanoic Acid

9. Unii-e0ymx3s4jd

10. Saroglitazarum

11. Saroglitazar [who-dd]

12. Chembl4297530

13. Schembl16346340

14. Dtxsid10197819

15. Chebi:134708

16. Bcp25470

17. Vua39909

18. Mfcd28502034

19. S9674

20. Cs-6149

21. Db13115

22. (2s)-2-ethoxy-3-(4-(2-(2-methyl-5-(4-(methylsulfanyl)phenyl)-1h-pyrrol-1-yl(ethoxy)phenyl)propanoic Acid

23. Hy-19937

24. P14958

25. A913988

26. Q15269693

27. (2s)-2-ethoxy-3-[4-(2-{2-methyl-5-[4-(methylthio)phenyl]-1h-pyrrol-1-yl}ethoxy)phenyl]propanoic Acid

28. (s)-alpha-ethoxy-4-[2-[-methyl-5-[4-(methylthio) Phenyl]-1h-pyrrol-1-yl]ethoxy]benzene-propanoic Acid

29. Benzenepropanoic Acid, .alpha.-ethoxy-4-(2-(2-methyl-5-(4-(methylthio)phenyl)-1h-pyrrol-1-yl)ethoxy)-, (.alpha.s)-

2.4 Create Date
2012-09-10
3 Chemical and Physical Properties
Molecular Weight 439.6 g/mol
Molecular Formula C25H29NO4S
XLogP34.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count11
Exact Mass439.18172958 g/mol
Monoisotopic Mass439.18172958 g/mol
Topological Polar Surface Area86 Ų
Heavy Atom Count31
Formal Charge0
Complexity532
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API SUPPLIERS

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Omgene Life Sciences Pvt. Ltd

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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  • WHO-GMP

Virtual BoothOmgene: R&D-based biopharmaceutical company with GMP facilities, focused on innovation and high-quality, affordable medicines.

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Taizhou Crene Biotechnology

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma Manufacturing 2024
Not Confirmed
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Taizhou Crene Biotechnology

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma Manufacturing 2024
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SynInnova Laboratories

Canada

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma Manufacturing 2024
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SynInnova Laboratories

Canada

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Tian Yuan Pharm

China

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Pharma Manufacturing 2024
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Tian Yuan Pharm

China

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Artis Biotech

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma Manufacturing 2024
Not Confirmed
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Artis Biotech

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Listed Suppliers

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  • fda
  • EDQM
  • WHO-GMP

Virtual BoothOmgene: R&D-based biopharmaceutical company with GMP facilities, focused on innovation and high-quality, affordable medicines.

Flag India
Digital Content Digital Content

Saroglitazar

About the Company : Omgene Life Sciences Private Limited is an R&D-driven biopharmaceutical company specializing in biopharmaceuticals, peptides, semi-synthetic, and synthetic actives. As a vertically...

Omgene Life Sciences Private Limited is an R&D-driven biopharmaceutical company specializing in biopharmaceuticals, peptides, semi-synthetic, and synthetic actives. As a vertically integrated company, we focus on developing high-quality formulations based on in-house-produced actives. With GMP-certified facilities and partnerships with contract manufacturers, we excel in formulation development for injectables, lyophilized injectables, complex generics, and oral peptide delivery systems, ensuring affordable, top-quality medicines.
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02

euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
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Saroglitazar

About the Company : We are among the global leaders in pharmaceutical standard manufacturing, offering a diverse range of products such as stable-isotope labeled internal standards, metabolites, degra...

We are among the global leaders in pharmaceutical standard manufacturing, offering a diverse range of products such as stable-isotope labeled internal standards, metabolites, degradation compounds/impurities, and inhibitor reference compounds. These products find extensive application in Bioanalysis (BA) for preclinical/early stage clinical studies and Bioequivalence (BE) studies essential for generic drug development.Moreover, we extend our expertise to provide stable-isotope labeled reference standards tailored for environmental and agricultural purposes.
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03

euroPLX 86 Munich
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euroPLX 86 Munich
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Saroglitazar

About the Company : SynInnova is established in 2008 for advanced chemistry services and as an innovative supplier of specialty organic chemicals and intermediates to pharmaceutical, agrochemical and ...

SynInnova is established in 2008 for advanced chemistry services and as an innovative supplier of specialty organic chemicals and intermediates to pharmaceutical, agrochemical and biotechnology sectors to support their drug discovery research. SynInnova as a contract research organization (CRO) provides high quality medicinal chemistry services, custom synthesis, process design and development. SynInnova has the capability of producing target compounds from milligrams to grams as per the customers' specifications.
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04

euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
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Saroglitazar

About the Company : Taizhou Crene Biotechnology Co., Ltd. is specialized in the manufacture of APIs, pharmaceutical intermediates. Our company is located in the largest API base in China - Taizhou and...

Taizhou Crene Biotechnology Co., Ltd. is specialized in the manufacture of APIs, pharmaceutical intermediates. Our company is located in the largest API base in China - Taizhou and Cooperated to established GMP standard production base and laboratory in surrounding areas. Our factory is a high-tech manufactory, which is committed to producing high quality pharmaceutical intermediates, promoting innovation in API technology and provide customized services for global pharmaceutical companies, dedicates itself on research, develop and industrialize of high-end intermediates & API.
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05

euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

Saroglitazar

About the Company : Tianyuan Pharmaceutical Co., Ltd. specializes in the research and development of targeted anticancer drugs and is dedicated to the exploration, production, and promotion of medical...

Tianyuan Pharmaceutical Co., Ltd. specializes in the research and development of targeted anticancer drugs and is dedicated to the exploration, production, and promotion of medical raw materials. The company's primary product line includes Crizotinib, Afatinib, Capmatinib, Aloitinib, Sorafenib, Ibrutinib, Lenvatinib, Mirogabalin, Omarigliptin, Peficitinib, as well as various other types of TINI API and intermediates.Tianyuan has established stable collaboration with amplification plants in Jiaozhou, Qingdao, facilitating the scaling up of production from 100kg to tonnage quantities.
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