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Chemistry

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Also known as: 125926-17-2, Sarpogrelate [inn], Sarpogrelate (inn), 4-[1-(dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]propan-2-yl]oxy-4-oxobutanoic acid, 19p708e787, Unii-19p708e787
Molecular Formula
C24H31NO6
Molecular Weight
429.5  g/mol
InChI Key
FFYNAVGJSYHHFO-UHFFFAOYSA-N
FDA UNII
19P708E787

Sarpogrelate
Sarpogrelate has been investigated for the treatment of Diabetes Mellitus, Diabetic Nephropathy, Coronary Artery Disease, and Renal Insufficiency, Chronic.
1 2D Structure

Sarpogrelate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[1-(dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]propan-2-yl]oxy-4-oxobutanoic acid
2.1.2 InChI
InChI=1S/C24H31NO6/c1-25(2)16-21(31-24(28)14-13-23(26)27)17-30-22-10-5-4-8-19(22)12-11-18-7-6-9-20(15-18)29-3/h4-10,15,21H,11-14,16-17H2,1-3H3,(H,26,27)
2.1.3 InChI Key
FFYNAVGJSYHHFO-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN(C)CC(COC1=CC=CC=C1CCC2=CC(=CC=C2)OC)OC(=O)CCC(=O)O
2.2 Other Identifiers
2.2.1 UNII
19P708E787
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(dimethylamino)-1-((2-(3-methoxyphenyl)phenoxy)methyl)ethyl Hydrogensuccinate Hydrochloride

2. Mci 9042

3. Mci-9042

4. Mono-(2-(dimethylamino)-1-((2-(2-(3-methoxyphenyl)ethyl)phenoxy)methyl)ethyl)succinate Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 125926-17-2

2. Sarpogrelate [inn]

3. Sarpogrelate (inn)

4. 4-[1-(dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]propan-2-yl]oxy-4-oxobutanoic Acid

5. 19p708e787

6. Unii-19p708e787

7. Ncgc00167489-01

8. Ncgc00167489-03

9. Schembl49197

10. Gtpl210

11. Chembl52939

12. Sarpogrelate [who-dd]

13. Dtxsid7048328

14. Chebi:135697

15. Bcp08179

16. Bdbm50093789

17. Stk631325

18. Akos005563803

19. Db12163

20. Ncgc00167489-02

21. 4-{[1-(dimethylamino)-3-{2-[2-(3-methoxyphenyl)ethyl]phenoxy}propan-2-yl]oxy}-4-oxobutanoic Acid

22. Hy-10563

23. Cs-0002654

24. Ft-0712621

25. Ls-187,118

26. D08508

27. Q44931

28. 159s512

29. L000858

30. Sr-01000883998

31. J-513134

32. Sr-01000883998-1

33. (+-)-2-(dimethylamino)-1-((o-(m-methoxyphenethyl)phenoxy)methyl)ethyl Hydrogen Succinate

34. (- )-2-(dimethylamino)-1-((o-(m-methoxyphenethyl)phenoxy)methyl)ethyl Hydrogen Succinate.

35. 4-(1-(dimethylamino)-3-(2-(3-methoxyphenethyl)phenoxy)propan-2-yloxy)-4-oxobutanoic Acid

36. 4-((1-(dimethylamino)-3-(2-(3-methoxyphenethyl)phenoxy)propan-2-yl)oxy)-4-oxobutanoic Acid

37. 4-(1-(2-(3-methoxyphenethyl)phenoxy)-3-(dimethylamino)propan-2-yloxy)-4-oxobutanoic Acid Sarpogrelate

38. 4-[1-dimethylamino-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]propan-2-yl]oxy-4-oxobutanoic Acid

39. Butanedioic Acid, Mono(2-(dimethylamino)-1-((2-(2-(3-methoxyphenyl)ethyl)phenoxy)methyl)ethyl) Ester

40. Butanedioic Acid,1-[2-(dimethylamino)-1-[[2-[2-(3-methoxyphenyl)ethyl]phenoxy]methyl]ethyl]ester

41. Succinic Acid Mono-(2-dimethylamino-1-{2-[2-(3-methoxy-phenyl)-ethyl]-phenoxymethyl}-ethyl) Ester; Hydrochloride

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 429.5 g/mol
Molecular Formula C24H31NO6
XLogP31.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count14
Exact Mass429.21513771 g/mol
Monoisotopic Mass429.21513771 g/mol
Topological Polar Surface Area85.3 Ų
Heavy Atom Count31
Formal Charge0
Complexity540
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Fibrinolytic Agents

Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN. (See all compounds classified as Fibrinolytic Agents.)


Serotonin Antagonists

Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS. (See all compounds classified as Serotonin Antagonists.)


Platelet Aggregation Inhibitors

Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. (See all compounds classified as Platelet Aggregation Inhibitors.)


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ABOUT THIS PAGE

Sarpogrelate Manufacturers

A Sarpogrelate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sarpogrelate, including repackagers and relabelers. The FDA regulates Sarpogrelate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sarpogrelate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sarpogrelate Suppliers

A Sarpogrelate supplier is an individual or a company that provides Sarpogrelate active pharmaceutical ingredient (API) or Sarpogrelate finished formulations upon request. The Sarpogrelate suppliers may include Sarpogrelate API manufacturers, exporters, distributors and traders.

Sarpogrelate GMP

Sarpogrelate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sarpogrelate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sarpogrelate GMP manufacturer or Sarpogrelate GMP API supplier for your needs.

Sarpogrelate CoA

A Sarpogrelate CoA (Certificate of Analysis) is a formal document that attests to Sarpogrelate's compliance with Sarpogrelate specifications and serves as a tool for batch-level quality control.

Sarpogrelate CoA mostly includes findings from lab analyses of a specific batch. For each Sarpogrelate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sarpogrelate may be tested according to a variety of international standards, such as European Pharmacopoeia (Sarpogrelate EP), Sarpogrelate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sarpogrelate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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