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Semaglutide

bachem semaglutide

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CCSB Semaglutide

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xyz-pharma-m-2024-10-07

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Supriya Semaglutide

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Transo-Pharm GmbH works globally to supply Active Pharmaceutical Ingredients adhering to the highest quality & GMP standards.

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xyz-pharma-m-2024-10-07

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CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

62 API Suppliers, 33 USDMF, 3 KDMF, 56 NDC API, 34 Listed Suppliers, $ API Reference Price

62 API Suppliers
33 USDMF
3 KDMF
56 NDC API
34 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

57 Drugs in Development

57 Drugs in Development

INTERMEDIATES

5 Intermediates Suppliers

5 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

70 FDF Dossiers, 14 FDA Orange Book, 12 Europe, 11 Canada, 4 Australia, 2 South Africa, 27 Listed Dossiers

70 FDF Dossiers
14 FDA Orange Book
12 Europe
11 Canada
4 Australia
2 South Africa
27 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

SOLUTION;SUBCUTANEOUS - 2MG/3ML (0.68MG/ML), SOLUTION;SUBCUTANEOUS - 2MG/1.5ML (1.34MG/ML), SOLUTION;SUBCUTANEOUS - 4MG/3ML (1.34MG/ML), SOLUTION;SUBCUTANEOUS - 8MG/3ML (2.68MG/ML)

drugProductComposition
SOLUTION;SUBCUTANEOUS - 2MG/3ML (0.68MG/ML)
SOLUTION;SUBCUTANEOUS - 2MG/1.5ML (1.34MG/ML)
SOLUTION;SUBCUTANEOUS - 4MG/3ML (1.34MG/ML)
SOLUTION;SUBCUTANEOUS - 8MG/3ML (2.68MG/ML)

RELATED EXCIPIENT COMPANIES

1 Nanjing Well Pharmaceutical, 1 BASF, 1 Finar, 1 Valens Pharmachem

relatedExcipients
1 Nanjing Well Pharmaceutical
1 BASF
1 Finar
1 Valens Pharmachem

EXCIPIENTS BY APPLICATIONS

3 Topical, 2 Film Formers & Plasticizers, 2 Solubilizers, 1 Emulsifying Agents, 1 Thickeners and Stabilizers, 1 Parenteral

excipientsByApplications
3 Topical
2 Film Formers & Plasticizers
2 Solubilizers
1 Emulsifying Agents
1 Thickeners and Stabilizers
1 Parenteral

DIGITAL CONTENT

10 DATA COMPILATION #PharmaFlow, 9 STOCK RECAP #PipelineProspector, 429 NEWS #PharmaBuzz

media
10 DATA COMPILATION #PharmaFlow
9 STOCK RECAP #PipelineProspector
429 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 12 Finished Drug Prices, 13 Annual Reports

globalSalesInformation
1 US Medicaid Prescriptions
12 Finished Drug Prices
13 Annual Reports

MARKET PLACE

47 APIs, 5 FDF Dossiers

marketPlace
47 APIs
5 FDF Dossiers

PATENTS & EXCLUSIVITIES

147 US Patents, 17 US Exclusivities

patents
147 US Patents
17 US Exclusivities

Bachem Semaglutide

Synopsis

ACTIVE PHARMA INGREDIENTS

62

API Suppliers

33

USDMF

0

CEP/COS

CEP/COS Certifications

0

JDMF

0

EU WC

3

KDMF

56

NDC API

0

VMF

34

Listed Suppliers

API REF. PRICE (USD/KG)

$

$ 651,163

MARKET PLACE

47

API

5

FDF

5INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

70

FDF Dossiers

14

FDA Orange Book

FDA (Orange Book)

12

Europe

11

Canada

4

Australia

2

South Africa

27

Listed Dossiers

57DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

147

US Patents

17

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

10

Data Compilation #PharmaFlow

9

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

429

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

2,147,483,647

Annual Reports (USD Million)

44,049

Finished Drug Prices

4 RELATED EXCIPIENT COMPANIES

10EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Nn9535, Ozempic, Rybelsus, 910463-68-2, Nn 9535, Nnc 0113-0217

Molecular Formula

C₁₈₇H₂₉₁N₄₅O₅₉

Molecular Weight

4114 g/mol

InChI Key

DLSWIYLPEUIQAV-CCUURXOWSA-N

Semaglutide

1 2D Structure

Semaglutide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

18-[[(1R)-4-[2-[2-[2-[2-[2-[2-[[(5S)-5-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-2-methylpropanoyl]amino]-4-carboxybutanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-carboxybutanoyl]amino]acetyl]amino]-5-oxopentanoyl]amino]propanoyl]amino]propanoyl]amino]-6-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[[2-[[(2S)-5-carbamimidamido-1-(carboxymethylamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-6-oxohexyl]amino]-2-oxoethoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethylamino]-1-carboxy-4-oxobutyl]amino]-18-oxooctadecanoic acid

2.1.2 InChI

InChI=1S/C187H291N45O59/c1-18-105(10)154(180(282)208-108(13)159(261)216-133(86-114-89-200-119-50-40-39-49-117(114)119)170(272)218-129(82-102(4)5)171(273)228-152(103(6)7)178(280)215-121(53-44-72-199-186(192)193)162(264)201-91-141(242)209-120(52-43-71-198-185(190)191)161(263)204-94-151(257)258)230-172(274)131(83-111-45-33-31-34-46-111)219-167(269)126(64-69-149(253)254)214-166(268)122(51-41-42-70-195-144(245)98-290-79-78-289-76-74-197-145(246)99-291-80-77-288-75-73-196-139(240)66-61-127(183(285)286)211-140(241)54-37-29-27-25-23-21-19-20-22-24-26-28-30-38-55-146(247)248)212-158(260)107(12)206-157(259)106(11)207-165(267)125(60-65-138(189)239)210-142(243)92-202-163(265)123(62-67-147(249)250)213-168(270)128(81-101(2)3)217-169(271)130(85-113-56-58-116(238)59-57-113)220-175(277)135(95-233)223-177(279)137(97-235)224-179(281)153(104(8)9)229-174(276)134(88-150(255)256)221-176(278)136(96-234)225-182(284)156(110(15)237)231-173(275)132(84-112-47-35-32-36-48-112)222-181(283)155(109(14)236)227-143(244)93-203-164(266)124(63-68-148(251)252)226-184(287)187(16,17)232-160(262)118(188)87-115-90-194-100-205-115/h31-36,39-40,45-50,56-59,89-90,100-110,118,120-137,152-156,200,233-238H,18-30,37-38,41-44,51-55,60-88,91-99,188H2,1-17H3,(H2,189,239)(H,194,205)(H,195,245)(H,196,240)(H,197,246)(H,201,264)(H,202,265)(H,203,266)(H,204,263)(H,206,259)(H,207,267)(H,208,282)(H,209,242)(H,210,243)(H,211,241)(H,212,260)(H,213,270)(H,214,268)(H,215,280)(H,216,261)(H,217,271)(H,218,272)(H,219,269)(H,220,277)(H,221,278)(H,222,283)(H,223,279)(H,224,281)(H,225,284)(H,226,287)(H,227,244)(H,228,273)(H,229,276)(H,230,274)(H,231,275)(H,232,262)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,285,286)(H4,190,191,198)(H4,192,193,199)/t105-,106-,107-,108-,109+,110+,118-,120-,121-,122-,123-,124-,125-,126-,127+,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,152-,153-,154-,155-,156-/m0/s1

2.1.3 InChI Key

DLSWIYLPEUIQAV-CCUURXOWSA-N

2.1.4 Canonical SMILES

CCC(C)C(C(=O)NC(C)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCC(C(=O)O)NC(=O)CCCCCCCCCCCCCCCCC(=O)O)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(C)(C)NC(=O)C(CC6=CN=CN6)N

2.1.5 Isomeric SMILES

CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](C(=O)O)NC(=O)CCCCCCCCCCCCCCCCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@H]([C@@H](C)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@H](CC6=CN=CN6)N

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Ozempic

2. Rybelsus

2.2.2 Depositor-Supplied Synonyms

1. Nn9535

2. Ozempic

3. Rybelsus

4. 910463-68-2

5. Nn 9535

6. Nnc 0113-0217

7. Nn-9535

8. Unii-53axn4nnhx

9. Semaglutide [usan:inn]

10. Wegovy

11. 53axn4nnhx

12. Rybelsus (oral Semaglutide)

13. Gtpl9724

14. Ozempic (injectable Semaglutide)

15. Chebi:167574

16. Ex-a2424

17. Ac-32580

18. Nnc-0113-0217

19. Rybelsus;ozempic;nn9535;og217sc;nnc 0113-0217

2.3 Create Date

2012-03-21

3 Chemical and Physical Properties

Molecular Formula	C₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight	4114 g/mol
XLogP3	-5.8
Hydrogen Bond Donor Count	57
Hydrogen Bond Acceptor Count	63
Rotatable Bond Count	151
Exact Mass	4112.1187318 g/mol
Monoisotopic Mass	4111.1153770 g/mol
Topological Polar Surface Area	1650 Å²
Heavy Atom Count	291
Formal Charge	0
Complexity	9590
Isotope Atom Count	0
Defined Atom Stereocenter Count	30
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Indication

Treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise:

- as monotherapy when metformin is considered inappropriate due to intolerance or contraindications;

- in addition to other medicinal products for the treatment of diabetes.

For study results with respect to combinations, effects on glycaemic control and cardiovascular events, and the populations studied, see sections 4. 4, 4. 5 and 5. 1.

Treatment of obesity

Treatment of type II diabetes mellitus

Rybelsus is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus to improve glycaemic control as an adjunct to diet and exercise

- as monotherapy when metformin is considered inappropriate due to intolerance or contraindications

- in combination with other medicinal products for the treatment of diabetes.

For study results with respect to combinations, effects on glycaemic control and cardiovascular events, and the populations studied, see sections 4. 4, 4. 5 and 5. 1.

Treatment of type II diabetes mellitus

Wegovy is indicated as an adjunct to a reduced-calorie diet and increased physical activity for weight management, including weight loss and weight maintenance, in adults with an initial Body Mass Index (BMI) of

- 30 kg/m (obesity), or

- 27 kg/m to < 30 kg/m (overweight) in the presence of at least one weight-related comorbidity e. g. dysglycaemia (prediabetes or type 2 diabetes mellitus), hypertension, dyslipidaemia, obstructive sleep apnoea or cardiovascular disease.

5 Pharmacology and Biochemistry

5.1 FDA Pharmacological Classification

5.1.1 Pharmacological Classes

Glucagon-Like Peptide 1 [CS]; Glucagon-like Peptide-1 (GLP-1) Agonists [MoA]; GLP-1 Receptor Agonist [EPC]

5.2 ATC Code

A10BJ06

A10BJ06

A10BJ06

A - Alimentary tract and metabolism

A10 - Drugs used in diabetes

A10B - Blood glucose lowering drugs, excl. insulins

A10BJ - Glucagon-like peptide-1 (glp-1) analogues

A10BJ06 - Semaglutide

API SUPPLIERS

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USDMF

01

Bachem Ag

Switzerland

Bio-Europe 2024

Bachem Group is a public, innovation-driven company specializing in the development and manufacturing of peptides and oligonucleotides.

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Switzerland

Digital Content

Semaglutide

GDUFA

DMF Review : Complete

Rev. Date : 2024-04-30

Pay. Date : 2023-03-02

DMF Number : 37594

Submission : 2023-03-16

Status : Active

Type : II

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02

Alp Pharm Beijing Co Ltd

China

AusBiotech 2024

Not Confirmed

03

Ambiopharm Inc

U.S.A

AusBiotech 2024

Not Confirmed

04

Polypeptide Sa

Switzerland

AusBiotech 2024

Not Confirmed

05

Polypeptide Sa

Switzerland

AusBiotech 2024

Not Confirmed

06

Shenzhen Jymed Technology Co Ltd

China

AusBiotech 2024

Not Confirmed

07

Sinopep-allsino Biopharmaceutical Co...

China

AusBiotech 2024

Not Confirmed

08

Sun Pharmaceutical Industries Ltd

India

AusBiotech 2024

Not Confirmed

09

Xiamen Sinopeg Biotech Co Ltd

China

AusBiotech 2024

Not Confirmed

10

Zhejiang Peptites Biotech Co Ltd

China

AusBiotech 2024

Not Confirmed

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KDMF

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NDC API

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Listed Suppliers

01

Bachem AG

Switzerland

Bio-Europe 2024

Bachem Group is a public, innovation-driven company specializing in the development and manufacturing of peptides and oligonucleotides.

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Switzerland

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Semaglutide

About the Company : With more than 50 years of experience and expertise, Bachem provides products for research, clinical development and commercial application to pharmaceutical and biotechnology comp...

With more than 50 years of experience and expertise, Bachem provides products for research, clinical development and commercial application to pharmaceutical and biotechnology companies worldwide, providing a wide range of services. Over the years, Bachem has established itself as a leading, innovation-driven company specializing in the development and manufacture of peptides and oligonucleotides. The company is headquartered in Switzerland and has offices in Europe, the US and Asia. The company is listed on the SIX Swiss Exchange.

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02

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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India

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Semaglutide

About the Company : Supriya Lifescience Ltd. specializes in API manufacturing, focusing on therapeutic segments like antihistamines, anti-allergic drugs, vitamins, anaesthetics and anti-asthmatics. Su...

Supriya Lifescience Ltd. specializes in API manufacturing, focusing on therapeutic segments like antihistamines, anti-allergic drugs, vitamins, anaesthetics and anti-asthmatics. Supriya follows industry standards and constantly improves to deliver quality products. Its facility is 47,000 square meters with dedicated areas for warehouse, QA, QC, R&D, production and finished products. The current capacity is 550 KL, with plans to expand to over 1000 KL by 2024. Supriya has 14 active USDMFs, 8 active CEPs, strong R&D and compliant facilities worldwide. Supriya works with innovators, generic companies, and as a CMO.

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03

Chunghwa Chemical Synthesis & Biote...

Taiwan

AusBiotech 2024

Not Confirmed

Chunghwa provides cost-effective APIs & advanced intermediates with complete DMF or COS, ensuring quality & reliable production.

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Taiwan

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Semaglutide

About the Company : Chunghwa Chemical Synthesis & Biotech Co. Ltd. (CCSB) offers global customers cost-effective APIs with speed, supported by our well-trained staff. As the first company in Southeast...

Chunghwa Chemical Synthesis & Biotech Co. Ltd. (CCSB) offers global customers cost-effective APIs with speed, supported by our well-trained staff. As the first company in Southeast Asia to receive FDA approval for synthetic and biotech APIs, CCSB has a proven track record of commercializing Statin, Immunosuppressant, Muscle Relaxant, and ACE Inhibitor APIs, all with complete DMF or COS. For years, CCSB has partnered with leading brand and generic drug companies to develop and produce APIs and advanced intermediates, focusing on specialty APIs crafted through a sophisticated fusion of fermentation and synthesis technologies in Taiwan.

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04

ChemWerth Inc

U.S.A

AusBiotech 2024

Not Confirmed

ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

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U.S.A

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Semaglutide

About the Company : Established in 1982, ChemWerth is a US-headquartered full-service generic active pharmaceutical ingredient (API) development and supply company. ChemWerth offers cGMP-quality APIs ...

Established in 1982, ChemWerth is a US-headquartered full-service generic active pharmaceutical ingredient (API) development and supply company. ChemWerth offers cGMP-quality APIs to regulated markets worldwide and has exclusive partnerships for new product development, compliance support and secure supply chain logistics. ChemWerth has access to over 500 APIs and more than 30 manufacturing facilities in the US, Europe, India and China. ChemWerth acts as a regulatory agent for over 25 FDA-approved facilities and sells more than 100 products. It has established its presence in 38 countries. In 2020, ChemWerth filed its 500th DMF with the FDA.

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05

Transo-Pharm USA LLC

U.S.A

AusBiotech 2024

Not Confirmed

TransoPharm USA works in the Sourcing and Management of Active Pharmaceutical Ingredients.

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U.S.A

Digital Content

Semaglutide

About the Company : Transo-Pharm, a fully licensed and certified distributor, specializes in pharmaceutical components for the health and veterinary industries. It offers support to clients throughout...

Transo-Pharm, a fully licensed and certified distributor, specializes in pharmaceutical components for the health and veterinary industries. It offers support to clients throughout the entire API life cycle, from product development through sales. Transo-Pharm serves as a sourcing and regulatory marketing agent for API manufacturers. It aids clients in establishing DMFs and provides GMP consulting. With a dedicated regulatory department, a warehouse, proprietary IPs for API processes, and partnerships with laboratories, Transo-Pharm offers a wide range of services. It operates from its offices in Shanghai, Hong Kong, Singapore, and the US.

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06

LGM Pharma

U.S.A

BioFlorida Conference

LGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

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Semaglutide

About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.

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07

Inabata France S.A.S

France

AusBiotech 2024

Not Confirmed

IKF/Pharmasynthese have been with fine chemicals market and APIs performance for more than 40 years.

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France

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Semaglutide

About the Company : Established in 1990, Inabata France, a part of the Inabata Group, used to export chemical and pharmaceutical products to Japan. In 2006, it acquired Pharmasynthèse. Today, Inabata...

Established in 1990, Inabata France, a part of the Inabata Group, used to export chemical and pharmaceutical products to Japan. In 2006, it acquired Pharmasynthèse. Today, Inabata-Pharmasynthèse offers a wide range of services, including sourcing, manufacturing, and the development of raw materials for the pharmaceutical and cosmetic industries. It supplies these ingredients to Europe, Japan, and other countries. With expertise in fine chemical production, Inabata-Pharmasynthèse conducts manufacturing operations, ranging from pilot to commercial quantities, at its GMP-certified facility at St. Pierre-Les-Elbeuf in France.

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08

Rochem International Inc

U.S.A

AusBiotech 2024

Not Confirmed

Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

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U.S.A

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Semaglutide

About the Company : Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quali...

Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quality ingredients manufactured in China. Headquartered in the Hauppauge, New York, Rochem has 16 offices spread across the globe to cater to the needs of its customers. Rochem’s operations are fully cGMP compliant and has been audited by the USFDA as well as several multinational organizations. It also trains and audits its partners to ensure all of their technologies and systems are FDA-compliant.

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09

Faran Shimi Pharmaceutical

Iran

AusBiotech 2024

Not Confirmed

Faran Shimi: Leading producer of high-quality APIs & alkaloid opiates, serving major pharmaceutical companies across the Middle East.

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Iran

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Semaglutide

About the Company : Faran Shimi Pharmaceutical Company, established in 2001 and affiliated with Golrang Pharmaceutical Investment Co, manufactures high-quality Active Pharmaceutical Ingredients (APIs)...

Faran Shimi Pharmaceutical Company, established in 2001 and affiliated with Golrang Pharmaceutical Investment Co, manufactures high-quality Active Pharmaceutical Ingredients (APIs) and finished dosage forms. For the past three years, the company focused on extracting alkaloid opiates, controlled substances, and narcotics. The APIs are widely used by major pharmaceutical companies nationwide and exported to the Middle East. All production adheres to local GMP standards in an SOP-driven environment with modern systems and utilities, ensuring the highest quality and safety.

Faran Shimi Pharmaceutical

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10

Chongqing Sintaho Pharmaceutical

China

AusBiotech 2024

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Chongqing Sintaho Pharma: A trusted partner globally for chemosynthetic APIs.

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China

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Semaglutide

About the Company : Sintaho Pharmaceutical Co., Ltd., located in Chongqing, China, contributes to being the most dependable partner for global pharmaceutical companies. Sintaho specializes in chemosyn...

Sintaho Pharmaceutical Co., Ltd., located in Chongqing, China, contributes to being the most dependable partner for global pharmaceutical companies. Sintaho specializes in chemosynthetic APIs (application contains oncology, nervous system, and metabolic diseases and etc.,) with a product portfolio ranging from small molecule APIs, ADC compounds (linkers and payloads) to polypeptides, also provides CDMO services of cytotoxic and OEB4/5 grade APIs.

Chongqing Sintaho Pharmaceutical

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HIGH-TECH INDUSTRIAL DEVELOPMENT ZONE,YANGZHOUCITY, JIANGSU PROVINCE 225100 CN","customerAddress":"#28 CANTON ROWS, PETBASHEERBAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723055400,"product":"SEMAGLUTIDE INTERMEDIATE P29 (IMPURITY)","address":"NO 31, RACE COURSE ROAD,BANGALORE","city":"BENGALURU,KARNATAKA","supplier":"HANGZHOU CELOR CHEMICAL","supplierCountry":"CHINA","foreign_port":"HANGCHOW (HANGZHOU)","customer":"MICRO LABS LIMITED","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"10","unit":"GMS","unitRateFc":"60","totalValueFC":"605.2","currency":"USD","unitRateINR":"5076","date":"08-Aug-2024","totalValueINR":"50760","totalValueInUsd":"605.2","indian_port":"Madras Air","hs_no":"29371900","bill_no":"4939485","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HANGCHOW (HANGZHOU)","supplierAddress":"BLOCK E-1804 WANTONG CENTER,189 DAGUAN ROAD,HANGZHOU, CHINA","customerAddress":"NO 31, RACE COURSE ROAD,BANGALORE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723141800,"product":"SEMAGLUTIDE INTERMEDIATE(SE02)","address":"CORPORATE HOUSE, NR. SOLA BRIDGE,,","city":"AHMEDABAD,GUJARAT","supplier":"ZHEJIANG Z-STAR PHARMA CO., LTD.","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"100","unit":"GMS","unitRateFc":"53","totalValueFC":"5345.6","currency":"USD","unitRateINR":"4483.8","date":"09-Aug-2024","totalValueINR":"448380","totalValueInUsd":"5345.6","indian_port":"Bombay Air","hs_no":"29371900","bill_no":"4976302","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"ROOM1507,EAST NO.1 BLDG.,TENGDA CENTRAL NO.1800 DONGHAI ROAD,BAIYUN STREET, JIAOJIANG DISTRICT,TAIZHOU CI China","customerAddress":"CORPORATE HOUSE, NR. SOLA BRIDGE,,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723573800,"product":"TBUO-STE-GLU(AEEA-AEEA-OH)-OTBU (SEMAGLUTIDE SIDE CHAIN) CAS: 1118767-16-0 (1 BOTTLE) (LAB CHEMICALS)","address":"ALEMBIC ROAD","city":"GUJARAT","supplier":"CHEMTOUR BIOTECH SUZHOU ","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"ALEMBIC PHARMACEUTICALS LIMITED","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"18000","totalValueFC":"1815.5","currency":"USD","unitRateINR":"1522800","date":"14-Aug-2024","totalValueINR":"152280","totalValueInUsd":"1815.5","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"5046915","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"41-1402, CECEP, NO.18 DONGCHANGROAD SUZHOU INDUSTRIAL PARK,JIANGSU PROVINCE CHINA","customerAddress":"ALEMBIC ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726511400,"product":"SEMAGLUTIDE","address":"159, C.S.T. ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"SHENZHEN JYMED TECHNOLOGY","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"LUPIN LTD","customerCountry":"INDIA","quantity":"0.05","actualQuantity":"50","unit":"GMS","unitRateFc":"350","totalValueFC":"17729.5","currency":"USD","unitRateINR":"29715","date":"17-Sep-2024","totalValueINR":"1485750","totalValueInUsd":"17729.5","indian_port":"Bombay Air","hs_no":"29371900","bill_no":"5641755","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"RM. 806-810, 1#8\/F BIOMEDICINE INNO VATION INDUSTRIAL PARK, NO.14 JINHU I RD, PINGSHAN DIST, SHENZHEN GD Sh China","customerAddress":"159, C.S.T. ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727029800,"product":"SEMAGLUTIDE SPEC-2(SAMPLES FOR TESTING)","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"DR. REDDY\\'S LABORATORIES","supplierCountry":"INDIA","foreign_port":"M\/S DR. REDDY SEZ","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"0.02","actualQuantity":"16","unit":"GMS","unitRateFc":"298.9","totalValueFC":"4828.6","currency":"USD","unitRateINR":"25290","date":"23-Sep-2024","totalValueINR":"404640","totalValueInUsd":"4828.6","indian_port":"Reddy r-SEZ\/Srikakulam","hs_no":"29371900","bill_no":"5745562","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"M\/S DR. REDDY SEZ","supplierAddress":"FTO-SEZ PROCESS UNIT-02 SECTOR SPECIFIC SEZ FOR APIs & SDNF India","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727029800,"product":"SEMAGLUTIDE (QTY: 50GMS, VALUE USD: 14500)","address":"PLOT NO.2, MAITRIVIHAR,","city":"HYDERABAD\/ANDHRA PRADESH","supplier":"SHENZHEN JYMED TECHNOLOGY","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"AUROBINDO PHARMA LIMITED","customerCountry":"INDIA","quantity":"0.05","actualQuantity":"0.05","unit":"KGS","unitRateFc":"290000","totalValueFC":"14638.2","currency":"USD","unitRateINR":"24534000","date":"23-Sep-2024","totalValueINR":"1226700","totalValueInUsd":"14638.2","indian_port":"Hyderabad Air","hs_no":"29371900","bill_no":"5746539","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"ADD: RM .806-810, 1#-8\/F BIOMEDICIN E INNOVATION INDUSTRIAL PARK, NO.14 JINHUI, RD, PINGSHAN DISTRICT, SHE China","customerAddress":"PLOT NO.2, MAITRIVIHAR,"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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Listed Dossiers

01

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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India

Digital Content

Regulatory Info :

Registration Country : India

Semaglutide

Brand Name :

Dosage Form : Subcutaneous Pen

Dosage Strength : 0.25MG/0.5ML

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Registration Country : India

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02

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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India

Digital Content

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Registration Country : India

Semaglutide

Brand Name :

Dosage Form : Subcutaneous Pen

Dosage Strength : 0.5MG/0.5ML

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Approval Date :

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Regulatory Info :

Registration Country : India

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03

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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India

Digital Content

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Registration Country : India

Semaglutide

Brand Name :

Dosage Form : Subcutaneous Pen

Dosage Strength : 1MG/0.5ML

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Application Number :

Regulatory Info :

Registration Country : India

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Digital Content

04

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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India

Digital Content

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Registration Country : India

Semaglutide

Brand Name :

Dosage Form : Subcutaneous Pen

Dosage Strength : 1.7MG/0.75ML

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Registration Country : India

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05

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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India

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Semaglutide

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Dosage Form : Subcutaneous Pen

Dosage Strength : 2.4MG/0.75ML

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Registration Country : India

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06

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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India

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Registration Country : India

Semaglutide

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Dosage Form : Tablet

Dosage Strength : 14MG

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Registration Country : India

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07

Pharmathen SA

Greece

AusBiotech 2024

Not Confirmed

Pharmathen provides life cycle Management solutions for branded pharma, as well as to develop & establish new technology platforms.

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Greece

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Regulatory Info : USA

Registration Country : Greece

Semaglutide

Brand Name :

Dosage Form : Tablet

Dosage Strength : 3MG

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Regulatory Info : USA

Registration Country : Greece

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08

Pharmathen SA

Greece

AusBiotech 2024

Not Confirmed

Pharmathen provides life cycle Management solutions for branded pharma, as well as to develop & establish new technology platforms.

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Greece

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Regulatory Info : USA

Registration Country : Greece

Semaglutide

Brand Name :

Dosage Form : Tablet

Dosage Strength : 7MG

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Regulatory Info : USA

Registration Country : Greece

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09

Pharmathen SA

Greece

AusBiotech 2024

Not Confirmed

Pharmathen provides life cycle Management solutions for branded pharma, as well as to develop & establish new technology platforms.

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Greece

Digital Content

Regulatory Info : USA

Registration Country : Greece

Semaglutide

Brand Name :

Dosage Form : Injection For Subcutan...

Dosage Strength : 2MG/1.5ML

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Approval Date :

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Regulatory Info : USA

Registration Country : Greece

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10

Pharmathen SA

Greece

AusBiotech 2024

Not Confirmed

Pharmathen provides life cycle Management solutions for branded pharma, as well as to develop & establish new technology platforms.

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Greece

Digital Content

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Registration Country : Greece

Semaglutide

Brand Name :

Dosage Form : Solution For Injection

Dosage Strength : 2MG/1.5ML

Packaging : Pre-filled Pen

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Registration Country : Greece

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DOSAGE - SOLUTION;SUBCUTANEOUS - 2MG/3ML (0.6...DOSAGE - SOLUTION;SUBCUTANEOUS - 2MG/3ML (0.68MG/ML)

USFDA APPLICATION NUMBER - 209637

DOSAGE - SOLUTION;SUBCUTANEOUS - 2MG/1.5ML (1...DOSAGE - SOLUTION;SUBCUTANEOUS - 2MG/1.5ML (1.34MG/ML)

USFDA APPLICATION NUMBER - 209637

DOSAGE - SOLUTION;SUBCUTANEOUS - 4MG/3ML (1.3...DOSAGE - SOLUTION;SUBCUTANEOUS - 4MG/3ML (1.34MG/ML)

USFDA APPLICATION NUMBER - 209637

DOSAGE - SOLUTION;SUBCUTANEOUS - 8MG/3ML (2.6...DOSAGE - SOLUTION;SUBCUTANEOUS - 8MG/3ML (2.68MG/ML)

USFDA APPLICATION NUMBER - 209637

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