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Chemistry

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Also known as: 57734-69-7, Sequifenadine [inn], 1-azabicyclo[2.2.2]octan-3-yl-bis(2-methylphenyl)methanol, C7q3tbr3fp, Bicarphene, 1-azabicyclo[2.2.2]oct-3-yl[bis(2-methylphenyl)]methanol hydrochloride
Molecular Formula
C22H27NO
Molecular Weight
321.5  g/mol
InChI Key
OXDOWGVJMITMJL-UHFFFAOYSA-N
FDA UNII
C7Q3TBR3FP

Sequifenadine
1 2D Structure

Sequifenadine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-azabicyclo[2.2.2]octan-3-yl-bis(2-methylphenyl)methanol
2.1.2 InChI
InChI=1S/C22H27NO/c1-16-7-3-5-9-19(16)22(24,20-10-6-4-8-17(20)2)21-15-23-13-11-18(21)12-14-23/h3-10,18,21,24H,11-15H2,1-2H3
2.1.3 InChI Key
OXDOWGVJMITMJL-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=CC=CC=C1C(C2CN3CCC2CC3)(C4=CC=CC=C4C)O
2.2 Other Identifiers
2.2.1 UNII
C7Q3TBR3FP
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Bicarfen

2. Bicarphen

3. Bicarphene

4. Bicarphene Hydrochloride

5. Bikarfen

6. Quinuclidinyl-3-di(o-tolyl)carbinol

7. Quinuclidyl-3-di-o-tolylcarbinol

2.3.2 Depositor-Supplied Synonyms

1. 57734-69-7

2. Sequifenadine [inn]

3. 1-azabicyclo[2.2.2]octan-3-yl-bis(2-methylphenyl)methanol

4. C7q3tbr3fp

5. Bicarphene

6. 1-azabicyclo[2.2.2]oct-3-yl[bis(2-methylphenyl)]methanol Hydrochloride

7. Sequifenadina

8. Sequifenadinum

9. Sequifenadinum [latin]

10. Sequifenadina [spanish]

11. Unii-c7q3tbr3fp

12. Brn 1548429

13. Alpha,alpha-di-o-tolyl-3-quinuclidinemethanol

14. Benzhydrol, 2,2'-dimethyl-alpha-(3-quinuclidinyl)-

15. 1-azabicyclo[2.2.2]octane-3-methanol, Alpha,alpha-bis(2-methylphenyl)-, Hydrochloride

16. 3-quinuclidinemethanol, Alpha,alpha-di-o-tolyl-

17. Sequifenadine [mart.]

18. Sequifenadine [who-dd]

19. Schembl1813871

20. Chembl2105505

21. Schembl11761803

22. Dtxsid40866647

23. Albb-014236

24. Stl026230

25. Akos005174257

26. Db13566

27. Hy-w281862

28. Ncgc00326051-01

29. Cs-0326942

30. D10510

31. Ab01321356-02

32. Sr-01000944892

33. Q4418107

34. Sr-01000944892-1

35. 1-azabicyclo[2.2.2]oct-3-yl[bis(2-methylphenyl)]methanol

36. (1-azabicyclo[2.2.2]octan-3-yl)bis(2-methylphenyl)methanol

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 321.5 g/mol
Molecular Formula C22H27NO
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass321.209264485 g/mol
Monoisotopic Mass321.209264485 g/mol
Topological Polar Surface Area23.5 Ų
Heavy Atom Count24
Formal Charge0
Complexity406
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

R - Respiratory system

R06 - Antihistamines for systemic use

R06A - Antihistamines for systemic use

R06AX - Other antihistamines for systemic use

R06AX32 - Sequifenadine


ABOUT THIS PAGE

Sequifenadine Manufacturers

A Sequifenadine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sequifenadine, including repackagers and relabelers. The FDA regulates Sequifenadine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sequifenadine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sequifenadine Suppliers

A Sequifenadine supplier is an individual or a company that provides Sequifenadine active pharmaceutical ingredient (API) or Sequifenadine finished formulations upon request. The Sequifenadine suppliers may include Sequifenadine API manufacturers, exporters, distributors and traders.

Sequifenadine GMP

Sequifenadine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sequifenadine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sequifenadine GMP manufacturer or Sequifenadine GMP API supplier for your needs.

Sequifenadine CoA

A Sequifenadine CoA (Certificate of Analysis) is a formal document that attests to Sequifenadine's compliance with Sequifenadine specifications and serves as a tool for batch-level quality control.

Sequifenadine CoA mostly includes findings from lab analyses of a specific batch. For each Sequifenadine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sequifenadine may be tested according to a variety of international standards, such as European Pharmacopoeia (Sequifenadine EP), Sequifenadine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sequifenadine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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