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Chemistry

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Also known as: 57734-70-0, Bicarphen, Bicarfen, Quinuclidin-3-yldi-o-tolylmethanol hydrochloride, 1-azabicyclo[2.2.2]oct-3-yl[bis(2-methylphenyl)]methanol hydrochloride, 305t85j01y
Molecular Formula
C22H28ClNO
Molecular Weight
357.9  g/mol
InChI Key
WCYWFJOJKZCSAJ-UHFFFAOYSA-N
FDA UNII
305T85J01Y

Sequifenadine Hydrochloride
1 2D Structure

Sequifenadine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-azabicyclo[2.2.2]octan-3-yl-bis(2-methylphenyl)methanol;hydrochloride
2.1.2 InChI
InChI=1S/C22H27NO.ClH/c1-16-7-3-5-9-19(16)22(24,20-10-6-4-8-17(20)2)21-15-23-13-11-18(21)12-14-23;/h3-10,18,21,24H,11-15H2,1-2H3;1H
2.1.3 InChI Key
WCYWFJOJKZCSAJ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=CC=CC=C1C(C2CN3CCC2CC3)(C4=CC=CC=C4C)O.Cl
2.2 Other Identifiers
2.2.1 UNII
305T85J01Y
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Bicarfen

2. Bicarphen

3. Bicarphene

4. Bicarphene Hydrochloride

5. Bikarfen

6. Quinuclidinyl-3-di(o-tolyl)carbinol

7. Quinuclidyl-3-di-o-tolylcarbinol

2.3.2 Depositor-Supplied Synonyms

1. 57734-70-0

2. Bicarphen

3. Bicarfen

4. Quinuclidin-3-yldi-o-tolylmethanol Hydrochloride

5. 1-azabicyclo[2.2.2]oct-3-yl[bis(2-methylphenyl)]methanol Hydrochloride

6. 305t85j01y

7. Bikarfen

8. 1-azabicyclo(2.2.2)octane-3-methanol, Alpha,alpha-bis(2-methylphenyl)-, Hydrochloride

9. 1-azabicyclo[2.2.2]oct-3-yl[bis(2-methylphenyl)]-methanol Hydrochloride

10. Unii-305t85j01y

11. (quinuclidyl-3)-di-(o-tolyl)carbinol Hydrochloride

12. Mls006010882

13. Schembl11764873

14. Dtxsid30973319

15. Mfcd17676104

16. Akos005110994

17. Alpha,alpha-bis(2-methylphenyl)-1-azabicyclo(2.2.2)octane-3-methanol Hydrochloride

18. Smr004701799

19. Sequifenadine Hydrochloride [who-dd]

20. Ft-0682670

21. Quinuclidin-3-yldi-o-tolylmethanolhydrochloride

22. A923088

23. 1-azabicyclo[2.2.2]octan-3-yl-bis(2-methylphenyl)methanol;hydrochloride

24. (1-azabicyclo[2.2.2]octan-3-yl)bis(2-methylphenyl)methanol--hydrogen Chloride (1/1)

25. 1-azabicyclo(2.2.2)octane-3-methanol, .alpha.,.alpha.-bis(2-methylphenyl)-, Hydrochloride (1:1)

2.4 Create Date
2011-02-22
3 Chemical and Physical Properties
Molecular Weight 357.9 g/mol
Molecular Formula C22H28ClNO
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass357.1859422 g/mol
Monoisotopic Mass357.1859422 g/mol
Topological Polar Surface Area23.5 Ų
Heavy Atom Count25
Formal Charge0
Complexity406
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2

ABOUT THIS PAGE

Sequifenadine Hydrochloride Manufacturers

A Sequifenadine Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sequifenadine Hydrochloride, including repackagers and relabelers. The FDA regulates Sequifenadine Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sequifenadine Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sequifenadine Hydrochloride Suppliers

A Sequifenadine Hydrochloride supplier is an individual or a company that provides Sequifenadine Hydrochloride active pharmaceutical ingredient (API) or Sequifenadine Hydrochloride finished formulations upon request. The Sequifenadine Hydrochloride suppliers may include Sequifenadine Hydrochloride API manufacturers, exporters, distributors and traders.

Sequifenadine Hydrochloride GMP

Sequifenadine Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sequifenadine Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sequifenadine Hydrochloride GMP manufacturer or Sequifenadine Hydrochloride GMP API supplier for your needs.

Sequifenadine Hydrochloride CoA

A Sequifenadine Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Sequifenadine Hydrochloride's compliance with Sequifenadine Hydrochloride specifications and serves as a tool for batch-level quality control.

Sequifenadine Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Sequifenadine Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sequifenadine Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Sequifenadine Hydrochloride EP), Sequifenadine Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sequifenadine Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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