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Chemistry

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Also known as: 7440-21-3, Si, Silicone, Silicon powder, Z4152n8iui, Mfcd00085311
Molecular Formula
Si
Molecular Weight
28.085  g/mol
InChI Key
XUIMIQQOPSSXEZ-UHFFFAOYSA-N
FDA UNII
Z4152N8IUI

Silicon
A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].
1 2D Structure

Silicon

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
silicon
2.1.2 InChI
InChI=1S/Si
2.1.3 InChI Key
XUIMIQQOPSSXEZ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
[Si]
2.2 Other Identifiers
2.2.1 UNII
Z4152N8IUI
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Silicon 28

2. Silicon-28

3. Silicone

4. Silicones

2.3.2 Depositor-Supplied Synonyms

1. 7440-21-3

2. Si

3. Silicone

4. Silicon Powder

5. Z4152n8iui

6. Mfcd00085311

7. 90337-93-2

8. Silicon Metal

9. Defoamer S-10

10. Silicon, Isotope Ofmass 32

11. Flots 100sco

12. Silicio

13. Silicon Dust

14. Silicon, Elemental

15. Silicon Powder, Crystalline, -325 Mesh

16. Polyeristalline Silicon Powder

17. Ccris 6599

18. Ccris 6831

19. Silicon Powder, Crystalline, -100+200 Mesh

20. Hsdb 5033

21. Hsdb 6351

22. Einecs 231-130-8

23. Einecs 232-263-4

24. Un1346

25. Un2203

26. Unii-z4152n8iui

27. Silicium

28. Silizium

29. Silicon Atom

30. Silicon Chips

31. Silicon, Disks, 15.9mm, Thickness 0.38mm, Single Crystal, N-type, 100%

32. Silicon Nanopowder

33. Silane, Compressed

34. Silicon, Cp

35. Unii-5j076063r1

36. Silicon Random Pieces

37. Silicon [inci]

38. Silicon, 99.0%

39. Silane [hsdb]

40. Silicon [ii]

41. Silicon [mi]

42. Silicon [mart.]

43. Silicon Powder, Amorphous

44. Silane [mi]

45. Silicon [who-dd]

46. 14si

47. Silicon Powder (amorphous)

48. Ec 231-130-8

49. Ec 232-263-4

50. Silicon (si), >98%

51. Dtxsid0051441

52. Dtxsid6052534

53. Silicon Powder (nanocrystalline)

54. Chebi:27573

55. Silicon, Elemental [hsdb]

56. Amy37004

57. Silicon Granular, Virgin Poly Fines

58. Silicon, Containing More Than 99.99 Per Cent By Weight Of Silicon

59. Akos004909675

60. Akos024438062

61. Silicon Rod, 2.5cm (0.98in) Dia

62. Silicon Rod, 5.08cm (2.0in) Dia

63. Db12982

64. Silicon Lump, 10cm (3.9in) & Down

65. Silicon Lump, 15cm (5.9in) & Down

66. Silicon Metal, Nist(r) Srm(r) 57b

67. Silicon Plate, 12.5mm (0.5in) Thick

68. Silicon Plate, 9.5mm (0.37in) Thick

69. Silicon Powder, Crystalline, -100 Mesh

70. Q670

71. Silicon Plate, 6.35mm (0.25in) Thick

72. Silicon Powder, Crystalline, Aps <=50nm

73. Silicon Powder, Nodular, Aps 1-5 Micron

74. Silicon Rod, 0.828cm (0.326in) Dia

75. Silicon Powder, Crystalline, Aps C=100nm

76. Silicon Powder, Crystalline, -100+325 Mesh

77. Silicon, Pieces, 99.95% Trace Metals Basis

78. Silicon Lump, 0.1-2.5cm (0.04-1.0in)

79. Silane, Compressed [un2203] [flammable Gas]

80. 803s625

81. Silicon Metal Powder Si Grade Ax 05 (h?gan?s)

82. Silicon Metal Powder Si Grade Ax 10 (h?gan?s)

83. Silicon Metal Powder Si Grade Ax 20 (h?gan?s)

84. Polysilicon, Monocrystalline Silicon, Silicon Ingots

85. Silicon Standard For Aas, Ready-to-use, In Hno3: Hf

86. Silicon, Powder, -325 Mesh, 99% Trace Metals Basis

87. Silicon Powder, Amorphous [un1346] [flammable Solid]

88. Polydispersed Silicon Nanowires, D X L 40 Nm X 1-20 Mum

89. Silicon, Aas Standard Solution, Specpure?, Si 1000?g/ml

90. Silicon, Powder, -60 Mesh, 99.999% Trace Metals Basis

91. Silicon, Rod, 100mm, Diameter 2.0mm, Crystalline, 100%

92. Silicon, Rod, 100mm, Diameter 25mm, Crystalline, 100%

93. Silicon, Rod, 100mm, Diameter 5.0mm, Crystalline, 100%

94. Silicon, Rod, 10mm, Diameter 2.0mm, Crystalline, 100%

95. Silicon, Rod, 25mm, Diameter 2.0mm, Crystalline, 100%

96. Silicon, Rod, 50mm, Diameter 2.0mm, Crystalline, 100%

97. Silicon, Rod, 50mm, Diameter 5.0mm, Crystalline, 100%

98. Silicon, Single Crystal, -111, Size, Thickness 0.4 Mm

99. Silicon Rod, Polycrystalline, Unpolished, 1.6cm (0.6in) Dia

100. Silicon, Nanopowder, <100 Nm (bet), <3% Oxygen Passivation

101. Silicon, Oil Based Standard Solution, Specpure, Si 5000g/g

102. Silicon, Oil Based Standard Solution, Specpure?, Si 1000?g/g

103. Silicon, Plasma Standard Solution, Specpure?, Si 10,000?g/ml

104. Silicon, Plasma Standard Solution, Specpure?, Si 1000?g/ml

105. Silicon, Rod, 20 Mm Diameter, Length 50 Mm, Purity 99.999%

106. Silicon, Rod, 20 Mm Diameter, Length 80 Mm, Purity 99.999%

107. Silicon Optical Window, 25.4mm (1.0in) Dia X 1mm (0.04in) Thick

108. Silicon Slugs, 9.5mm (0.375in) Dia X 9.5mm (0.375in) Length

109. Silicon, Disks, 13mm, Thickness 0.38mm, Single Crystal, 100%

110. Silicon, Lump, 25 Mm Max. Lump Size, Weight 50 G, Purity 99.95%

111. Silicon, Lump, 25 Mm Max. Lump Size, Weight 50 G, Purity 99.99%

112. Silicon, Lump, 5 Mm Max. Lump Size, Weight 100 G, Purity 99.99%

113. Silicon, Lump, 5 Mm Max. Lump Size, Weight 200 G, Purity 99.99%

114. Silicon, Lump, 5 Mm Max. Lump Size, Weight 50 G, Purity 99.99%

115. Silicon, Lump, 5 Mm Max. Lump Size, Weight 500 G, Purity 99.99%

116. Silicon, Rod, 25 Mm Diameter, Length 150 Mm, Purity 99.999%

117. Silicon, Rod, Length 100 Mm, 20 Mm Diameter, Purity 99.999%

118. Silicon, Sphere, 0.48 Mm Diameter, 10_pcs, Tolerance +/-2.5um

119. Silicon, Sphere, 0.48 Mm Diameter, 20 Pcs, Tolerance +/-2.5um

120. Silicon, Sphere, 0.48 Mm Diameter, 50 Pcs, Tolerance +/-2.5um

121. Silicon, Sphere, 10pcs, Diameter 2.0mm, Precision Sphere Grade 25

122. Silicon, Sphere, 20pcs, Diameter 2.0mm, Precision Sphere Grade 25

123. Silicon, Sphere, 50pcs, Diameter 2.0mm, Precision Sphere Grade 25

124. Silicon 99.999% Polycrystalinedisc And Sputtering Targets Available Also

125. Silicon Sputtering Target, 50.8mm (2.0in) Dia X 3.18mm (0.125in) Thick

126. Silicon Sputtering Target, 50.8mm (2.0in) Dia X 6.35mm (0.250in) Thick

127. Silicon Sputtering Target, 76.2mm (3.0in) Dia X 6.35mm (0.250in) Thick

128. Silicon, Lump, 25 Mm Max. Lump Size, Weight 100 G, Purity 99.95%

129. Silicon, Lump, 25 Mm Max. Lump Size, Weight 100 G, Purity 99.99%

130. Silicon, Lump, 25 Mm Max. Lump Size, Weight 100 G, Purity 99.999%

131. Silicon, Lump, 25 Mm Max. Lump Size, Weight 200 G, Purity 99.95%

132. Silicon, Lump, 25 Mm Max. Lump Size, Weight 200 G, Purity 99.99%

133. Silicon, Lump, 25 Mm Max. Lump Size, Weight 200 G, Purity 99.999%

134. Silicon, Lump, 25 Mm Max. Lump Size, Weight 50 G, Purity 99.999%

135. Silicon, Lump, 25 Mm Max. Lump Size, Weight 500 G, Purity 99.95%

136. Silicon, Lump, 25 Mm Max. Lump Size, Weight 500 G, Purity 99.99%

137. Silicon, Powder, 45 Max. Part. Size (micron), Weight 50 G, Purity 99.5%

138. Silicon, Rod, 40mm, Diameter 20mm, Single Crystal, -100, 99.999%

139. Silicon, Rod, 40mm, Diameter 20mm, Single Crystal, -111, 99.999%

140. Silicon, Rod, 50mm, Diameter 5mm, Single Crystal, -100, 99.999%

141. Silicon, Rod, 50mm, Diameter 5mm, Single Crystal, -111, 99.999%

142. Silicon, Rod, 50mm, Diameter 6mm, Single Crystal, -111, 99.999%

143. Silicon, Rod, 80mm, Diameter 20mm, Single Crystal, -100, 99.999%

144. Silicon, Sheet, 10x10mm, Thickness 0.5mm, Single Crystal, -100, 100%

145. Silicon, Sheet, 10x10mm, Thickness 0.6mm, Single Crystal, -100, 100%

146. Silicon, Sheet, 14x14mm, Thickness 1.0mm, Single Crystal, -100, 100%

147. Silicon, Sheet, 14x14mm, Thickness 1.0mm, Single Crystal, -111, 100%

148. Silicon, Sheet, 25x25mm, Thickness 1.0mm, Polycrystalline, 99.999%

149. Silicon, Sheet, 25x25mm, Thickness 1.0mm, Single Crystal, -100, 100%

150. Silicon, Sheet, 40x40mm, Thickness 3.0mm, Single Crystal, P-type, 100%

151. Silicon, Sheet, 52x52mm, Thickness 1.0mm, Polycrystalline, 99.999%

152. Silicon, Nanopowder, <100 Nm Particle Size (tem), >=98% Trace Metals Basis

153. Silicon, Powder, 150 Max. Part. Size (micron), Weight 1000 G, Purity 97.5%

154. Silicon, Powder, 150 Max. Part. Size (micron), Weight 200 G, Purity 97.5%

155. Silicon, Powder, 150 Max. Part. Size (micron), Weight 2000 G, Purity 97.5%

156. Silicon, Powder, 45 Max. Part. Size (micron), Purity 99.95%, Weight 200 G

157. Silicon, Powder, 45 Max. Part. Size (micron), Weight 10 G, High Purity 99.999%

158. Silicon, Powder, 45 Max. Part. Size (micron), Weight 100 G, High Purity 99.998%

159. Silicon, Powder, 45 Max. Part. Size (micron), Weight 100 G, Purity 99.95%

160. Silicon, Powder, 45 Max. Part. Size (micron), Weight 20 G, High Purity 99.998%

161. Silicon, Powder, 45 Max. Part. Size (micron), Weight 50 G, Purity 99.95%

162. Silicon, Powder, Max. Particle Size 150 Micron, Weight 100 G, Purity 97.5%

163. Silicon, Powder, Max. Particle Size 150 Micron, Weight 500 G, Purity 97.5%

164. Silicon, Powder, Max. Particle Size 45 Micron, Weight 100 G, Purity 99.5%

165. Silicon, Powder, Max. Particle Size 45 Micron, Weight 200 G, Purity 99.5%

166. Silicon, Powder, Max. Particle Size 45 Micron, Weight 50 G, High Purity 99.998%

167. Silicon, Rod, 100mm, Diameter 10.0mm, Single Crystal - Random Orientation, 100%

168. Silicon, Rod, 100mm, Diameter 12.7mm, Single Crystal - Random Orientation, 100%

169. Silicon, Rod, 25mm, Diameter 3.15mm, Single Crystal - Random Orientation, 100%

170. Silicon, Rod, 50mm, Diameter 3.15mm, Single Crystal - Random Orientation, 100%

171. Silicon, Single Crystal, -111, P-type, Boron Doped, Diameter 57mm, Length 1.0mm, 100%

172. Silicon, Nist(r) Srm(r) 640e, Powder, Line Position And Line Shape Standard For Powder Diffraction

173. Silicon, Single Crystal, -100, N-type, Phosphorus Doped, Diameter 150mm, Length 0.65mm, 100%

174. Silicon, Single Crystal, -100, N-type, Phosphorus Doped, Diameter 76.2mm, Length 0.38mm, 100%

175. Silicon, Single Crystal, -100, N-type, Phosphorus Doped, Diameter 76.2mm, Length 2.0mm, 100%

176. Silicon, Single Crystal, -100, P-type, Boron Doped, Diameter 76.2mm, Length 0.38mm, 100%

177. Silicon, Single Crystal, -111, N-type, Phosphorus Doped, Diameter 76.2mm, Length 0.38mm, 100%

178. Silicon, Single Crystal, -111, N-type, Phosphorus Doped, Diameter 76.2mm, Length 0.50mm, 100%

179. Silicon, Single Crystal, -111, N-type, Phosphorus Doped, Diameter 76.2mm, Length 0.75mm, 100%

180. Silicon, Single Crystal, -111, P-type, Boron Doped, Diameter 76.2mm, Length 0.38mm, 100%

181. Silicon, Sputtering Target, Diam. X Thickness 2.00 In. X 0.25 In., 99.999% Trace Metals Basis

182. Silicon, Wafer (single Side Polished), <100>, N-type, Contains No Dopant, Diam. X Thickness 2 In. X 0.5 Mm

183. Silicon, Wafer (single Side Polished), <100>, N-type, Contains No Dopant, Diam. X Thickness 3 In. X 0.5 Mm

184. Silicon, Wafer (single Side Polished), <100>, N-type, Contains Phosphorus As Dopant, Diam. X Thickness 2 In. X 0.5 Mm

185. Silicon, Wafer (single Side Polished), <100>, N-type, Contains Phosphorus As Dopant, Diam. X Thickness 3 In. X 0.5 Mm

186. Silicon, Wafer (single Side Polished), <100>, P-type, Contains Boron As Dopant, Diam. X Thickness 2 In. X 0.5 Mm

187. Silicon, Wafer (single Side Polished), <100>, P-type, Contains Boron As Dopant, Diam. X Thickness 3 In. X 0.5 Mm

188. Silicon, Wafer (single Side Polished), <111>, N-type, Contains No Dopant, Diam. X Thickness 2 In. X 0.5 Mm

189. Silicon, Wafer (single Side Polished), <111>, N-type, Contains No Dopant, Diam. X Thickness 3 In. X 0.5 Mm

190. Silicon, Wafer (single Side Polished), <111>, P-type, Contains Boron As Dopant, Diam. X Thickness 3 In. X 0.5 Mm

191. Silicon, Wafer (single Side Polished), Contains Phosphorus As Dopant, <111>, N-type, Diam. X Thickness 2 In. X 0.5 Mm

192. Silicon, Wafer, <111>, P-type, Contains Boron As Dopant, Diam. X Thickness 2 In. X 0.3 Mm

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 28.085 g/mol
Molecular Formula Si
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count0
Rotatable Bond Count0
Exact Mass27.976926534 g/mol
Monoisotopic Mass27.976926534 g/mol
Topological Polar Surface Area0 Ų
Heavy Atom Count1
Formal Charge0
Complexity0
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Trace Elements

A group of chemical elements that are needed in minute quantities for the proper growth, development, and physiology of an organism. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) (See all compounds classified as Trace Elements.)


4.2 Absorption, Distribution and Excretion

In 36 patients suffering from chronic renal failure (mean creatinine clearance 26 mL/min), serum silicon levels were significantly increased (mean 0.52 microgram/mL compared with 0.265 microgram/mL in normals; p less than 0.005). Urinary silicon excretion per 24 hr was significantly decreased (15.71 mg/24 hr compared with 21.4 mg/24 hr in normals; p less than 0.001). Fractional excretion of silicon (FESi) was significantly increased in chronic renal failure (p less than 0.001), with overall tubular secretion of silicon in 33% of patients. Urinary excretion of silicon was significantly related to urinary calcium excretion (p less than 0.0001) urinary magnesium excretion (p less than 0.0001) creatinine clearance (p less than 0.05) and sodium excretion (p less than 0.05). It is suggested that urinary silicon is in the form of orthosilicate, principally bound to calcium and magnesium; and that in chronic renal failure the increase in FESi, and the decrease in absorbed Si from the gastrointestinal tract, moderate the increase in plasma silicon levels and prevent excessive entry of silicon into the tissues.

PMID:3748249 Adler AJ, Berlyne GM; Nephton 44 (1): 36-9 (1986)


The substance can be absorbed into the body by inhalation.

International Program on Chemical Safety/Commission of the European Communities; International Chemical Safety Card on Silicon (November 2003). Available from, as of May 20, 2010: https://www.inchem.org/pages/icsc.html


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(WEST)"}]
01-Jan-2021
30-Nov-2024
KGS
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Quantity (KGS) & Unit rate (USD/KGS) over time

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ABOUT THIS PAGE

Silicon Manufacturers

A Silicon manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Silicon, including repackagers and relabelers. The FDA regulates Silicon manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Silicon API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Silicon Suppliers

A Silicon supplier is an individual or a company that provides Silicon active pharmaceutical ingredient (API) or Silicon finished formulations upon request. The Silicon suppliers may include Silicon API manufacturers, exporters, distributors and traders.

click here to find a list of Silicon suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Silicon USDMF

A Silicon DMF (Drug Master File) is a document detailing the whole manufacturing process of Silicon active pharmaceutical ingredient (API) in detail. Different forms of Silicon DMFs exist exist since differing nations have different regulations, such as Silicon USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Silicon DMF submitted to regulatory agencies in the US is known as a USDMF. Silicon USDMF includes data on Silicon's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Silicon USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Silicon suppliers with USDMF on PharmaCompass.

Silicon JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Silicon Drug Master File in Japan (Silicon JDMF) empowers Silicon API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Silicon JDMF during the approval evaluation for pharmaceutical products. At the time of Silicon JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Silicon suppliers with JDMF on PharmaCompass.

Silicon GMP

Silicon Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Silicon GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Silicon GMP manufacturer or Silicon GMP API supplier for your needs.

Silicon CoA

A Silicon CoA (Certificate of Analysis) is a formal document that attests to Silicon's compliance with Silicon specifications and serves as a tool for batch-level quality control.

Silicon CoA mostly includes findings from lab analyses of a specific batch. For each Silicon CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Silicon may be tested according to a variety of international standards, such as European Pharmacopoeia (Silicon EP), Silicon JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Silicon USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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