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    Bora Pharmaceuticals- Making success more certain.

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    Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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    Seqens Sitagliptin Malate

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    Axplora- The partner of choice for complex APIs.

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    Fareva is a one-stop-shop for API/HPAPI, OSD & Sterile products, is USFDA, EMA and PMDA-inspected and has multiple NDA & ANDA filings.

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    Chemistry

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    Also known as:
    Molecular Formula
    C20H19F6N5O6-2
    Molecular Weight
    539.4  g/mol
    InChI Key
    ASAFEPPKGUGNEZ-AMMWVCRBSA-L
    Sitagliptin Malate
    1 2D Structure

    Sitagliptin Malate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;(2S)-2-hydroxybutanedioate
    2.1.2 InChI
    InChI=1S/C16H15F6N5O.C4H6O5/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22;5-2(4(8)9)1-3(6)7/h4,6,9H,1-3,5,7,23H2;2,5H,1H2,(H,6,7)(H,8,9)/p-2/t9-;2-/m10/s1
    2.1.3 InChI Key
    ASAFEPPKGUGNEZ-AMMWVCRBSA-L
    2.1.4 Canonical SMILES
    C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(CC3=CC(=C(C=C3F)F)F)N.C(C(C(=O)[O-])O)C(=O)[O-]
    2.1.5 Isomeric SMILES
    C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.C([C@@H](C(=O)[O-])O)C(=O)[O-]
    2.2 Create Date
    2017-11-15
    3 Chemical and Physical Properties
    Molecular Weight 539.4 g/mol
    Molecular Formula C20H19F6N5O6-2
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count15
    Rotatable Bond Count5
    Exact Mass539.12395232 g/mol
    Monoisotopic Mass539.12395232 g/mol
    Topological Polar Surface Area178 Ų
    Heavy Atom Count37
    Formal Charge-2
    Complexity684
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2

    API SUPPLIERS

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    Seqens

    France

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    Teva API

    Israel

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    Teva API

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    USDMF CEP/COS JDMF EU-WCarrow-down
    ✖

    Date of Issue : 2022-06-22

    Valid Till : 2025-05-20

    Written Confirmation Number : WC-0001

    Address of the Firm :

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    Registrant Name : Samo Pharmaceutical Co., Ltd.

    Registration Date : 2016-01-05

    Registration Number : Wed2991-24-ND

    Manufacturer Name : Teva API India Ltd

    Manufacturer Address : Plot No. Q.1 to 4, Industrial Area, Ghirongi, Malanpur, Distt. Behind (MP) India_x000D_

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    Laurus Labs

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    Laurus Labs

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    USDMF CEP/COS JDMF EU-WCInactive-api
    ✖

    Date of Issue : 2022-06-27

    Valid Till : 2022-11-27

    Written Confirmation Number : WC-0459A3

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    Sitagliptin Malate IH

    Date of Issue : 2022-06-27

    Valid Till : 2022-11-27

    Written Confirmation Number : WC-0459A3

    Address of the Firm : Unit-4, Plot No 25, 25A to 25K, Atchutapuram, Rambilli, Visakhapatnam District-5...

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    Sitagliptin Malate IH

    Date of Issue : 2022-06-22

    Valid Till : 2025-05-20

    Written Confirmation Number : WC-0001

    Address of the Firm : Q-1-4,Industrial area ,Ghinrongi Malanpur -477 117, Dist -Bhind (MP)

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    Sitagliptin malate

    Registrant Name : Samo Pharmaceutical Co., Ltd.

    Registration Date : 2016-01-05

    Registration Number : Wed2991-24-ND

    Manufacturer Name : Teva API India Ltd

    Manufacturer Address : Plot No. Q.1 to 4, Industrial Area, Ghirongi, Malanpur, Distt. Behind (MP) India_x000...

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    Seqens

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    Sitagliptin Malate

    About the Company : Since its inception in 2003, Seqens has grown to become a global leader in pharmaceutical solutions and specialty ingredients. Seqens supports its customers in developing, scaling ...

    Since its inception in 2003, Seqens has grown to become a global leader in pharmaceutical solutions and specialty ingredients. Seqens supports its customers in developing, scaling up and manufacturing drug substances from the pre-clinical phase to the commercial phase. It offers a large portfolio of APIs and proprietary products. Seqens also develops custom solutions and ingredients for the most demanding industries, such as healthcare, electronics and cosmetics. Its unique range of technologies enables it to manufacture complex molecules for small- and large-scale demands. It operates 24 industrial plants and 10 R&D centres across the globe.
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    Sitagliptin Malate

    About the Company : Teva API is a standalone business unit within Teva Pharmaceutical Industries, the world’s largest generic drug manufacturer. Employing over 4,000 professionals at 15 internationa...

    Teva API is a standalone business unit within Teva Pharmaceutical Industries, the world’s largest generic drug manufacturer. Employing over 4,000 professionals at 15 international plant sites and 6 R&D centers, Teva API is a leading international supplier of active pharmaceutical ingredients (APIs) with the industry’s broadest portfolio of over 350 products. Its leadership in cutting-edge development, large-scale production capacity and global support make it an ideal API partner of choice. Over its more than 85 years of existence, Teva API has acquired and established top-rated manufacturing and development facilities around the world.
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    API Reference Price

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    [{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1632940200,"product":"SITAGLIPTIN MALATE","address":"2ND FLOOR, SERENE CHAMBERS,ROAD NO. 7, BANJARA HILLS,","city":"HYDEABAD.AP","supplier":"LAURUS LABS","supplierCountry":"INDIA","foreign_port":"TEL AVIV YAFO","customer":"TEVA PHARMACEUTICAL INDUSTRIES","customerCountry":"ISRAEL","quantity":"60.00","actualQuantity":"60","unit":"KGS","unitRateFc":"650","totalValueFC":"37889.3","currency":"USD","unitRateINR":46450,"date":"30-Sep-2021","totalValueINR":"2787000","totalValueInUsd":"37889.3","indian_port":"HYDERABAD AIR","hs_no":"29339990","bill_no":"4970928","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ISRAEL","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"2ND FLOOR, SERENE CHAMBERS,ROAD NO. 7, BANJARA HILLS,, HYDEABAD.AP","customerAddress":""},{"dataSource":"API 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Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1667845800,"product":"SITAGLIPTIN MALATE CONTROL BATCH NO 1508","address":"12th floor,Commerz II, International Business Park, Oberoi","city":"Goregaon East","supplier":"TEVA API","supplierCountry":"INDIA","foreign_port":"LISBON","customer":"TECNIMEDE","customerCountry":"PORTUGAL","quantity":"163.89","actualQuantity":"163.89","unit":"KGS","unitRateFc":"853.6","totalValueFC":"140713.5","currency":"USD","unitRateINR":70071.389346512908,"date":"08-Nov-2022","totalValueINR":"11484000","totalValueInUsd":"140713.5","indian_port":"DELHI AIR","hs_no":"29335990","bill_no":"5315747","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"DELHI AIR","supplierAddress":"12th floor,Commerz II, International Business Park, Oberoi, Goregaon East","customerAddress":""},{"dataSource":"API 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    30-Sep-2021
    29-Jun-2024
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    Akums gets DCGI nod for triple combination diabetes medication
    Akums gets DCGI nod for triple combination diabetes medication

    27 Jul 2023

    // ECONOMIC TIMES

    https://economictimes.indiatimes.com/industry/healthcare/biotech/pharmaceuticals/akums-gets-dcgi-nod-for-triple-combination-diabetes-medication/articleshow/102172327.cms?utm_source=contentofinterest&utm_medium=text&utm_campaign=cppst

    ECONOMIC TIMES
    27 Jul 2023
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    Merck set to remove cancer-causing chemical from top diabetes drugs
    Merck set to remove cancer-causing chemical from top diabetes drugs

    18 Jan 2023

    // REUTERS

    https://www.reuters.com/business/healthcare-pharmaceuticals/merck-set-remove-cancer-causing-chemical-top-diabetes-drugs-bloomberg-news-2023-01-17/

    REUTERS
    18 Jan 2023
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    Sitagliptin combinations for diabetics to be sold at JAKs
    Sitagliptin combinations for diabetics to be sold at JAKs

    18 Sep 2022

    // EXPRESSPHARMA

    https://www.expresspharma.in/sitagliptin-combinations-for-diabetics-to-be-sold-at-jaks/

    EXPRESSPHARMA
    18 Sep 2022
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    Codexis & Merck Amend and Extend Supply Agreement for Enzyme Used in Sitagliptin
    Codexis & Merck Amend and Extend Supply Agreement for Enzyme Used in Sitagliptin

    09 Sep 2021

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2021/09/09/2294779/24825/en/Codexis-and-Merck-Amend-and-Extend-Supply-Agreement-for-Enzyme-Used-in-Manufacture-of-Sitagliptin.html

    GLOBENEWSWIRE
    09 Sep 2021
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