Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 USDMF

1 API Suppliers
1 USDMF

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 426253-04-5, Smp-601, Sm-216601, Pz-601, 26020h3q1l, (4r,5s,6s)-3-[[4-[(5s)-2,5-dihydro-5-methyl-1h-pyrrol-3-yl]-2-thiazolyl]thio]-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Molecular Formula

C₁₈H₂₁N₃O₄S₂

Molecular Weight

407.5 g/mol

InChI Key

XFGOMLIRJYURLQ-GOKYHWASSA-N

FDA UNII

26020H3Q1L

Razupenem is a broad-spectrum carbapenem with activity against gram-positive bacteria, including methicillin-resistant S. aureus.

1 2D Structure

Sm-216601

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-3-[[4-[(5S)-5-methyl-2,5-dihydro-1H-pyrrol-3-yl]-1,3-thiazol-2-yl]sulfanyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

2.1.2 InChI

InChI=1S/C18H21N3O4S2/c1-7-4-10(5-19-7)11-6-26-18(20-11)27-15-8(2)13-12(9(3)22)16(23)21(13)14(15)17(24)25/h4,6-9,12-13,19,22H,5H2,1-3H3,(H,24,25)/t7-,8+,9+,12+,13+/m0/s1

2.1.3 InChI Key

XFGOMLIRJYURLQ-GOKYHWASSA-N

2.1.4 Canonical SMILES

CC1C=C(CN1)C2=CSC(=N2)SC3=C(N4C(C3C)C(C4=O)C(C)O)C(=O)O

2.1.5 Isomeric SMILES

C[C@H]1C=C(CN1)C2=CSC(=N2)SC3=C(N4[C@H]([C@H]3C)[C@H](C4=O)[C@@H](C)O)C(=O)O

2.2 Other Identifiers

2.2.1 UNII

26020H3Q1L

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Sm-216601

2.3.2 Depositor-Supplied Synonyms

1. 426253-04-5

2. Smp-601

3. Sm-216601

4. Pz-601

5. 26020h3q1l

6. (4r,5s,6s)-3-[[4-[(5s)-2,5-dihydro-5-methyl-1h-pyrrol-3-yl]-2-thiazolyl]thio]-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid

7. (4r,5s,6s)-6-((r)-1-hydroxyethyl)-4-methyl-3-((4-((s)-5-methyl-2,5-dihydro-1h-pyrrol-3-yl)thiazol-2-yl)thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid

8. (4r,5s,6s)-6-[(1r)-1-hydroxyethyl]-4-methyl-3-[[4-[(5s)-5-methyl-2,5-dihydro-1h-pyrrol-3-yl]-1,3-thiazol-2-yl]sulfanyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid

9. (4r,5s,6s)-3-[[4-[(5s)-2,5-dihydro-5-methyl-1h-pyrrol-3-yl]-2-thiazolyl]thio]-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid

10. (4r,5s,6s)-6-((1r)-1-hydroxyethyl)-4-methyl-3-((4-((5s)-5-methyl-2,5-dihydro-1h-pyrrol-3-yl)thiazol-2-yl)sulfanyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic Acid

11. 1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic Acid, 3-((4-((5s)-2,5-dihydro-5-methyl-1h-pyrrol-3-yl)-2-thiazolyl)thio)-6-((1r)-1-hydroxyethyl)-4-methyl-7-oxo-, (4r,5s,6s)-

12. Razupenem [usan]

13. (4r,5s,6s)-6-((r)-1-hydroxyethyl)-4-methyl-3-((4-((s)-5-methyl-2,5-dihydro-1h-pyrrol-3-yl)thiazol-2-yl)thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic A

14. Razupenem [usan:inn]

15. Unii-26020h3q1l

16. (4r,5s,6s)-6-[(1r)-1-hydroxyethyl]-4-methyl-3-({4-[(5s)-5-methyl-2,5-dihydro-1h-pyrrol-3-yl]-1,3-thiazol-2-yl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid

17. (4r,5s,6s)-6-[(1r)-1-hydroxyethyl]-4-methyl-3-({4-[(5s)-5-methyl-2,5-dihydro-1h-pyrrol-3-yl}-1,3-thiazol-2-yl)sulfanyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid

18. Razupenem [inn]

19. Razupenem (usan/inn)

20. Razupenem [who-dd]

21. Schembl2894324

22. Chembl1256722

23. Gtpl10851

24. Dtxsid801045429

25. Zinc3986713

26. Db12587

27. D09658

28. 253d045

29. Q15410192

2.4 Create Date

2006-10-26

3 Chemical and Physical Properties

Molecular Formula	C₁₈H₂₁N₃O₄S₂
Molecular Weight	407.5 g/mol
XLogP3	-1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	5
Exact Mass	407.09734851 g/mol
Monoisotopic Mass	407.09734851 g/mol
Topological Polar Surface Area	156 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	740
Isotope Atom Count	0
Defined Atom Stereocenter Count	5
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1