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1. Bms 387032
2. Bms-387032
3. Bms387032
4. Sns 032
5. Sns-032
1. Sns-032
2. 345627-80-7
3. Bms-387032
4. Sns 032
5. Bms 387032
6. N-(5-(((5-(tert-butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide
7. N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide
8. Sns-032 (bms-387032)
9. Bms387032
10. Sns032
11. N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide
12. Sns-032 (hydrochloride)
13. N-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-yl)piperidine-4-carboxamide
14. N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide
15. Chembl296468
16. 345627-80-7 (free Base)
17. 4-piperidinecarboxamide, N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-
18. 9979i93686
19. Bms-387072
20. N-(5-((5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl)-1,3-thiazol-2-yl)piperidine-4-carboxamide
21. Unii-9979i93686
22. Kinome_3820
23. Mls006011029
24. Schembl187401
25. Bdbm5931
26. Gtpl5670
27. Sns 032 [who-dd]
28. Chebi:91399
29. Cid_3025986
30. Amy2872
31. Dtxsid50188100
32. Ex-a054
33. Bcpp000066
34. Hms3295g09
35. Hms3654g10
36. Act06674
37. Bcp01951
38. Zinc3816409
39. Mfcd09833875
40. Nsc767048
41. Nsc799362
42. S1145
43. Akos015898717
44. Ccg-264835
45. Db05969
46. Nsc-767048
47. Nsc-799362
48. Sb16651
49. N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-peridinecarboxamide
50. Compound 21 [pmid: 15027863]
51. Ncgc00263167-01
52. Ncgc00263167-02
53. Ac-26846
54. As-35116
55. Hy-10008
56. Smr004702824
57. Sns-032(bms-387032)
58. Sns-032 - Bms-387032
59. A6078
60. Ft-0674612
61. Sw219478-1
62. A20554
63. 627b807
64. J-019645
65. J-523350
66. Brd-k43389698-001-01-6
67. Q27075347
68. N-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-yl)piperidine-4-carboxamide;sns-032
69. 56h
70. N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-peridinecarboxam
71. N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]-thio]-2-thiazolyl]-4-piperidinecarboxamide
| Molecular Weight | 380.5 g/mol |
|---|---|
| Molecular Formula | C17H24N4O2S2 |
| XLogP3 | 3 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 6 |
| Exact Mass | 380.13406837 g/mol |
| Monoisotopic Mass | 380.13406837 g/mol |
| Topological Polar Surface Area | 134 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 454 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in cancer/tumors (unspecified), leukemia (unspecified), lymphoma (unspecified), multiple myeloma, and solid tumors.
SNS-032 is a potent and selective inhibitor of CDKs 2, 7 and 9, which are critical in the communication and relay of signals to promote cellular growth and function. CDK2 is involved in cellular proliferation by regulating the initiation of and progression through the DNA-synthesis phase of the cell cycle. CDK7 and CDK9 are involved in transcriptional regulation of certain proteins involved in cell survival. Inappropriate activity by these CDKs can lead to unregulated proliferation, avoidance of apoptosis and increased cell survival, all of which are hallmarks of cancer. By selectively targeting these CDKs, SNS-032 may halt both aberrant cell proliferation and induce apoptosis.
ABOUT THIS PAGE
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PharmaCompass offers a list of Sns-032 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Sns-032 manufacturer or Sns-032 supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Sns-032 manufacturer or Sns-032 supplier.
PharmaCompass also assists you with knowing the Sns-032 API Price utilized in the formulation of products. Sns-032 API Price is not always fixed or binding as the Sns-032 Price is obtained through a variety of data sources. The Sns-032 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A SNS 032 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of SNS 032, including repackagers and relabelers. The FDA regulates SNS 032 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. SNS 032 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A SNS 032 supplier is an individual or a company that provides SNS 032 active pharmaceutical ingredient (API) or SNS 032 finished formulations upon request. The SNS 032 suppliers may include SNS 032 API manufacturers, exporters, distributors and traders.
SNS 032 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of SNS 032 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right SNS 032 GMP manufacturer or SNS 032 GMP API supplier for your needs.
A SNS 032 CoA (Certificate of Analysis) is a formal document that attests to SNS 032's compliance with SNS 032 specifications and serves as a tool for batch-level quality control.
SNS 032 CoA mostly includes findings from lab analyses of a specific batch. For each SNS 032 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
SNS 032 may be tested according to a variety of international standards, such as European Pharmacopoeia (SNS 032 EP), SNS 032 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (SNS 032 USP).
