Find Ethacrynate Sodium manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Sodium ethacrynate, 6500-81-8, Ethacrynic acid sodium, Ethacrynate sodium [usan:usp], Etacrynate sodium, K41myv7mpm
Molecular Formula
C13H11Cl2NaO4
Molecular Weight
325.12  g/mol
InChI Key
CWCSCNSKBSCYCS-UHFFFAOYSA-M
FDA UNII
K41MYV7MPM

Ethacrynate Sodium
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
1 2D Structure

Ethacrynate Sodium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate
2.1.2 InChI
InChI=1S/C13H12Cl2O4.Na/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17;/h4-5H,2-3,6H2,1H3,(H,16,17);/q;+1/p-1
2.1.3 InChI Key
CWCSCNSKBSCYCS-UHFFFAOYSA-M
2.1.4 Canonical SMILES
CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)[O-])Cl)Cl.[Na+]
2.2 Other Identifiers
2.2.1 UNII
K41MYV7MPM
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Acid, Etacrynic

2. Acid, Ethacrinic

3. Acid, Ethacrynic

4. Edecrin

5. Etacrynic Acid

6. Ethacrinic Acid

7. Ethacrynic Acid

8. Ethacrynic Acid, Sodium Salt

9. Hydromedin

10. Sodium, Ethacrynate

2.3.2 Depositor-Supplied Synonyms

1. Sodium Ethacrynate

2. 6500-81-8

3. Ethacrynic Acid Sodium

4. Ethacrynate Sodium [usan:usp]

5. Etacrynate Sodium

6. K41myv7mpm

7. Ethacrynic Acid Sodium Salt

8. Sodium (2,3-dichloro-4-(2-methylenebutyryl)phenoxy)acetate

9. Edecrin Sodium

10. Sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate

11. Acetic Acid, (2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy)-, Sodium Salt

12. Sodium Edecrin

13. Ethacrynate Sodium [usan]

14. Unii-k41myv7mpm

15. Sodium Etacrynate

16. Ethacrynate Sodium (usp)

17. Schembl42210

18. Chembl1200487

19. Dtxsid10215320

20. Sodium Etacrynate [mart.]

21. Ethacrynate Sodium [vandf]

22. Etacrynate Sodium [who-dd]

23. Ethacrynate Sodium [orange Book]

24. Ethacrynate Sodium [usp Impurity]

25. Ethacrynic Acid Sodium Salt [mi]

26. D04079

27. Q27281933

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 325.12 g/mol
Molecular Formula C13H11Cl2NaO4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass323.9932085 g/mol
Monoisotopic Mass323.9932085 g/mol
Topological Polar Surface Area66.4 Ų
Heavy Atom Count20
Formal Charge0
Complexity375
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Diuretics

Agents that promote the excretion of urine through their effects on kidney function. (See all compounds classified as Diuretics.)


Enzyme Inhibitors

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)


4.2 FDA Pharmacological Classification
4.2.1 Pharmacological Classes
Loop Diuretic [EPC]; Increased Diuresis at Loop of Henle [PE]

API Reference Price

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07-Jul-2021
07-Jul-2021
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Looking for 6500-81-8 / Ethacrynate Sodium API manufacturers, exporters & distributors?

Ethacrynate Sodium manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Ethacrynate Sodium API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ethacrynate Sodium manufacturer or Ethacrynate Sodium supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ethacrynate Sodium manufacturer or Ethacrynate Sodium supplier.

PharmaCompass also assists you with knowing the Ethacrynate Sodium API Price utilized in the formulation of products. Ethacrynate Sodium API Price is not always fixed or binding as the Ethacrynate Sodium Price is obtained through a variety of data sources. The Ethacrynate Sodium Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Ethacrynate Sodium

Synonyms

Sodium ethacrynate, 6500-81-8, Ethacrynic acid sodium, Ethacrynate sodium [usan:usp], Etacrynate sodium, K41myv7mpm

Cas Number

6500-81-8

Unique Ingredient Identifier (UNII)

K41MYV7MPM

About Ethacrynate Sodium

A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.

sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate Manufacturers

A sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate, including repackagers and relabelers. The FDA regulates sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate Suppliers

A sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate supplier is an individual or a company that provides sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate active pharmaceutical ingredient (API) or sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate finished formulations upon request. The sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate suppliers may include sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate API manufacturers, exporters, distributors and traders.

click here to find a list of sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate WC

A sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate written confirmation (sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate WC) is an official document issued by a regulatory agency to a sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate manufacturer, verifying that the manufacturing facility of a sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate APIs or sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate finished pharmaceutical products to another nation, regulatory agencies frequently require a sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate WC (written confirmation) as part of the regulatory process.

click here to find a list of sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate suppliers with Written Confirmation (WC) on PharmaCompass.

sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate suppliers with NDC on PharmaCompass.

sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate GMP

sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate GMP manufacturer or sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate GMP API supplier for your needs.

sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate CoA

A sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate CoA (Certificate of Analysis) is a formal document that attests to sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate's compliance with sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate specifications and serves as a tool for batch-level quality control.

sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate CoA mostly includes findings from lab analyses of a specific batch. For each sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate may be tested according to a variety of international standards, such as European Pharmacopoeia (sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate EP), sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (sodium;2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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