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Chemistry

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Also known as: Sodium alginate, 9005-38-3, Natriumglucuronat, Schembl20919851, Ft-0621962, Ft-0670280
Molecular Formula
C6H9NaO7
Molecular Weight
216.12  g/mol
InChI Key
MSXHSNHNTORCAW-UHFFFAOYSA-M

Sodium Alginate
Salts and esters of ALGINIC ACID that are used as HYDROGELS; DENTAL IMPRESSION MATERIALS, and as absorbent materials for surgical dressings (BANDAGES, HYDROCOLLOID). They are also used to manufacture MICROSPHERES and NANOPARTICLES for DIAGNOSTIC REAGENT KITS and DRUG DELIVERY SYSTEMS.
1 2D Structure

Sodium Alginate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;3,4,5,6-tetrahydroxyoxane-2-carboxylate
2.1.2 InChI
InChI=1S/C6H10O7.Na/c7-1-2(8)4(5(10)11)13-6(12)3(1)9;/h1-4,6-9,12H,(H,10,11);/q;+1/p-1
2.1.3 InChI Key
MSXHSNHNTORCAW-UHFFFAOYSA-M
2.1.4 Canonical SMILES
C1(C(C(OC(C1O)O)C(=O)[O-])O)O.[Na+]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Alginate

2. Alginate, Barium

3. Alginate, Calcium

4. Alginate, Copper

5. Alginate, Potassium

6. Alginate, Sodium

7. Alginate, Sodium Calcium

8. Alginates

9. Alginic Acid, Barium Salt

10. Alginic Acid, Calcium Salt

11. Alginic Acid, Copper Salt

12. Alginic Acid, Potassium Salt

13. Alginic Acid, Sodium Salt

14. Alloid G

15. Barium Alginate

16. Calcium Alginate

17. Calcium Alginate, Sodium

18. Calginat

19. Copper Alginate

20. Kalrostat

21. Kalrostat 2

22. Kaltostat

23. Poly(mannuronic Acid), Sodium Salt

24. Potassium Alginate

25. Sodium Alginate

26. Sodium Calcium Alginate

27. Vocoloid

28. Xantalgin

2.2.2 Depositor-Supplied Synonyms

1. Sodium Alginate

2. 9005-38-3

3. Natriumglucuronat

4. Schembl20919851

5. Ft-0621962

6. Ft-0670280

7. Sodium;3,4,5,6-tetrahydroxyoxane-2-carboxylate

2.3 Create Date
2005-09-18
3 Chemical and Physical Properties
Molecular Weight 216.12 g/mol
Molecular Formula C6H9NaO7
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count7
Rotatable Bond Count1
Exact Mass216.02459690 g/mol
Monoisotopic Mass216.02459690 g/mol
Topological Polar Surface Area130 Ų
Heavy Atom Count14
Formal Charge0
Complexity210
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count5
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Therapeutic Uses

Mesh Heading: Radiation-protective agents, hemostatics, biocompatible materials

National Library of Medicine, SIS; ChemIDplus Record for Algin (9005-38-3). Available from, as of April 17, 2006: https://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp


EXPTL USE: Alginate therapy (20 mg Na alginate; 40 mg manucol SS/LD/2) applied immediately after single oral contaminantion with radiostrontium (0.2-0.4 uCi/mL) reduced skeletal retention of radiostrontium.

KADIC M; VETERINARIA (SARAJAVO) 24 (2) 219-34 (1975)


EXPTL USE: Alginated bread fed to mice increased (85)Sr concentration in blood, decreased urinary excretion and increased fecal excretion.

VAN DER BORGHT ET AL; MINER METAB LAB, STUDIECENT KERNENERG CENT ETUDE ENERG NUCL, MOL, BELG


EXPTL USE: Absorption in mice of strontium, barium, and radium was depressed more than that of calcium by alginates tested, include sodium alginate.

HUMPHREYS ET AL; INT CONF STRONTIUM METAB (PAP) 2ND; VOL CONF-720818, 1973, 309-314


For more Therapeutic Uses (Complete) data for ALGIN (8 total), please visit the HSDB record page.


5 Pharmacology and Biochemistry
5.1 Absorption, Distribution and Excretion

Apparently ... not decomposed or absorbed appreciably when ingested ...

Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. II-155


When propyleneglycol (14)C alginate or (14)C propylene glycol alginate ... dosed to mice, unhydrolyzed ester and alginate residue ... unabsorbed from GI tract; but any hydrolyzed propyleneglycol ... absorbed ... metabolized and eliminated ... single dose ... 1 g/kg ... excreted ... feces ... 5 days ...

The Chemical Society. Foreign Compound Metabolism in Mammals Volume 3. London: The Chemical Society, 1975., p. 343


... After a dose of 5 g/kg, traces of label were still present in rectum. Alginate prepared from laminaria digitata was unabsorbed by rats fed at a level of 10% of their daily diet.

The Chemical Society. Foreign Compound Metabolism in Mammals Volume 3. London: The Chemical Society, 1975., p. 343


API SUPPLIERS

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Inabata France S.A.S

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Virtual BoothIKF/Pharmasynthese have been with fine chemicals market and APIs performance for more than 40 years.

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Rochem International Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Virtual BoothRochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

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Pharm-RX Chemical

U.S.A

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Virtual BoothPharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

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Qingdao Bright Moon Seaweed Group

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Qingdao Bright Moon Seaweed Group

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Innova Remedies

India

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Innova Remedies

India

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KDMF

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Sodium alginate

Registrant Name : YuYu Pharmaceutical Co., Ltd.

Registration Date : 2022-09-28

Registration Number : 20220328-211-J-1256(1)

Manufacturer Name : IFF N&H Norway AS

Manufacturer Address : Steinhauvegen 1, VORMEDAL, NO-5545, Norway

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Sodium alginate

Registrant Name : Parmarine Co., Ltd.

Registration Date : 2022-03-28

Registration Number : 20220328-211-J-1256

Manufacturer Name : IFF N&H Norway AS

Manufacturer Address : Steinhaugvegen 1, VORMEDAL, NO-5545, Norway

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Listed Suppliers

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Virtual BoothIKF/Pharmasynthese have been with fine chemicals market and APIs performance for more than 40 years.

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Sodium Alginate

About the Company : Established in 1990, Inabata France, a part of the Inabata Group, used to export chemical and pharmaceutical products to Japan. In 2006, it acquired Pharmasynthèse. Today, Inabata...

Established in 1990, Inabata France, a part of the Inabata Group, used to export chemical and pharmaceutical products to Japan. In 2006, it acquired Pharmasynthèse. Today, Inabata-Pharmasynthèse offers a wide range of services, including sourcing, manufacturing, and the development of raw materials for the pharmaceutical and cosmetic industries. It supplies these ingredients to Europe, Japan, and other countries. With expertise in fine chemical production, Inabata-Pharmasynthèse conducts manufacturing operations, ranging from pilot to commercial quantities, at its GMP-certified facility at St. Pierre-Les-Elbeuf in France.
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Virtual BoothRochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

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Sodium Alginate

About the Company : Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quali...

Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quality ingredients manufactured in China. Headquartered in the Hauppauge, New York, Rochem has 16 offices spread across the globe to cater to the needs of its customers. Rochem’s operations are fully cGMP compliant and has been audited by the USFDA as well as several multinational organizations. It also trains and audits its partners to ensure all of their technologies and systems are FDA-compliant.
Rochem

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Virtual BoothPharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

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Digital Content Digital Content

Sodium Alginate

About the Company : Pharm-Rx has earned an outstanding reputation since its establishment in 1991, serving as a reputable importer and distributor of active ingredients to the pharmaceutical, nutritio...

Pharm-Rx has earned an outstanding reputation since its establishment in 1991, serving as a reputable importer and distributor of active ingredients to the pharmaceutical, nutritional supplement, and food industries. The company maintains an exceptionally selective approach to its suppliers, personally visiting manufacturers overseas to ensure the highest standards. The sustained growth of Pharm-Rx can be attributed to its steadfast commitment to three core values: quality ingredients, competitive pricing, and unparalleled customer service.
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Sodium Alginate

About the Company : Innova Remedies manufactures and markets an outstanding range of API's. It is a steadily growing company founded in 1993 in Nagpur, the central zone of India. Over the year it has...

Innova Remedies manufactures and markets an outstanding range of API's. It is a steadily growing company founded in 1993 in Nagpur, the central zone of India. Over the year it has evolved as a major manufacturer and expanded to cater the requirement of industry and in the process of its growth has established a formidable reputation for itself. Our strength and comparative advantage lies with our most important resource, people. Our intelligent and dedicated employees value the integrity, creativity and efficiency.
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API Reference Price

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[{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710181800,"product":"SODIUM ALGINATE ( FOC FOR R&D PURPOSE)","address":"304,ATLANTA ARCADE,","city":"MUMBAI MAHARASHTRA","supplier":"QINGDAO HYZLIN BIOLOGY DEVLOPMENT C","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"MACLEODS PHARMACEUTICALS LTD","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"50","totalValueFC":"50.4","currency":"USD","unitRateINR":"4187.5","date":"12-Mar-2024","totalValueINR":"4187.5","totalValueInUsd":"50.4","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"2539481","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"O LTD . NO.8 LONGQUANHE 5TH ROAD IN QINGDAO, NORTHERN INDUSTRIAL PARK, JIMO. QINGDAO ,CHINA CHINA","customerAddress":"304,ATLANTA ARCADE,"}]
12-Mar-2024
12-Mar-2024
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Europe

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Calcium Carbonate; Magnesium Carbonate; sodium alginate

Brand Name : Gastren Duo

Dosage Form : Oral Suspension

Dosage Strength : 600MG; 70MG; 150MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Turkey

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sodium alginate; Potassium Bicarbonate; Calcium Carbonate

Brand Name : Refubel Advance

Dosage Form : Oral Suspension

Dosage Strength : 1G/10ML; 0.2G/10ML; 0.2G/10ML

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Registration Country : Turkey

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sodium alginate; Sodium Bicarbonate; Calcium Carbonate

Brand Name : Refubel

Dosage Form : Oral Suspension

Dosage Strength : 0.5G/10ML; 0.267G/10ML; 0.160G/10ML

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Approval Date :

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Regulatory Info :

Registration Country : Turkey

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sodium alginate; Potassium Bicarbonate

Brand Name : Gavion Advance

Dosage Form : Sodium Alginate+Potassium Bicarbonate 10Ml 20 Joined' Oral Use

Dosage Strength : 20 bust os suspe 10 ml mint

Packaging :

Approval Date :

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Regulatory Info :

Registration Country : Italy

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sodium alginate; Potassium Bicarbonate

Brand Name : Gavion Advance

Dosage Form : Sodium Alginate+Potassium Bicarbonate 200Ml Oral Use

Dosage Strength : os suspe 200 ml

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Approval Date :

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Regulatory Info :

Registration Country : Italy

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Medlab Asia & Asia Health
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sodium alginate; Potassium Bicarbonate

Brand Name : Gavion Advance

Dosage Form : Sodium Alginate+Potassium Bicarbonate 200Ml Oral Use

Dosage Strength : os suspe 200 ml mint 1,000 mg/10 ml + 200 mg/10 ml

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Approval Date :

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Regulatory Info :

Registration Country : Italy

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Medlab Asia & Asia Health
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sodium alginate; Potassium Bicarbonate

Brand Name : Gavion Advance

Dosage Form : Sodium Alginate+Potassium Bicarbonate 500Ml Oral Use

Dosage Strength : os suspe 500 ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Medlab Asia & Asia Health
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sodium alginate; Potassium Bicarbonate

Brand Name : Gavion Advance

Dosage Form : Sodium Alginate+Potassium Bicarbonate 500Ml Oral Use

Dosage Strength : os suspe 500 ml mint 1,000 mg/10 ml + 200 mg/10 ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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09

Medlab Asia & Asia Health
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Alginate Natrii; Hydrogenocarbon Natrii; Calcium Carbonate

Brand Name : Gavisconell Liquid Mint

Dosage Form : Susp In Flasche

Dosage Strength :

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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10

Medlab Asia & Asia Health
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Sodium Alginate

Brand Name :

Dosage Form : Oral Liquid

Dosage Strength : 10ML

Packaging : 10ml Liquid Stick-Packs

Approval Date :

Application Number :

Regulatory Info : File-Available; France

Registration Country : France

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