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Chemistry

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Also known as: 7647-14-5, Salt, Table salt, Halite, Saline, Rock salt
Molecular Formula
ClNa
Molecular Weight
58.44  g/mol
InChI Key
FAPWRFPIFSIZLT-UHFFFAOYSA-M
FDA UNII
451W47IQ8X

Sodium Chloride
A ubiquitous sodium salt that is commonly used to season food.
1 2D Structure

Sodium Chloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;chloride
2.1.2 InChI
InChI=1S/ClH.Na/h1H;/q;+1/p-1
2.1.3 InChI Key
FAPWRFPIFSIZLT-UHFFFAOYSA-M
2.1.4 Canonical SMILES
[Na+].[Cl-]
2.2 Other Identifiers
2.2.1 UNII
451W47IQ8X
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Sodium Chloride, (22)na

2. Sodium Chloride, (24)nacl

2.3.2 Depositor-Supplied Synonyms

1. 7647-14-5

2. Salt

3. Table Salt

4. Halite

5. Saline

6. Rock Salt

7. Common Salt

8. Dendritis

9. Purex

10. Sodium Chloric

11. Iodized Salt

12. Top Flake

13. Sodium Chloride (nacl)

14. Hyposaline

15. Sodium Monochloride

16. Flexivial

17. Gingivyl

18. Slow Sodium

19. Sea Salt

20. Nacl

21. Ss Salt

22. Sodiumchloride

23. Natriumchlorid

24. Adsorbanac

25. Hypersal

26. Sodium;chloride

27. Trisodium Trichloride

28. White Crystal

29. H.g. Blending

30. Salt (ingredient)

31. Colyte

32. Isotonic Saline

33. Sodium Chloride (na4cl4)

34. Caswell No. 754

35. Normal Saline

36. Natrum Muriaticum

37. Extra Fine 200 Salt

38. Extra Fine 325 Salt

39. Sodium Chloride Brine, Purified

40. Arm-a-vial

41. Ccris 982

42. Dendritic Salt

43. Hsdb 6368

44. Epa Pesticide Chemical Code 013905

45. 14762-51-7

46. Sodium Chloride Solution

47. Mfcd00003477

48. Nsc-77364

49. Sodium Chloride, Hypertonic

50. Ls-1700

51. 10% Sodium Chloride Injection

52. Chebi:26710

53. 451w47iq8x

54. Ayr

55. Buffer Solution, Tisab

56. Sodium Chloride, Ultra Dry

57. Sodium Chloride Solution, 5 M

58. Natriumchlorid [german]

59. Broncho Saline

60. Sodium, Reference Standard Solution

61. Halite (nacl)

62. Sodium Chloride, Acs Reagent, >=99.0%

63. Sodium-36 Chloride

64. Einecs 231-598-3

65. Nsc 77364

66. Sodium Chloride Physiological Solution, Bioultra, Tablet

67. Sodium Chloride (na36cl)

68. Sodium Chloride [usp:jan]

69. Isotonic

70. Kochsalz

71. Mafiron

72. Rocksalt

73. Titrisol

74. Cloruro Sodico

75. Sodium-chloride

76. Solsel

77. Unii-451w47iq8x

78. Natrii Chloridum

79. Saline Solution

80. Sea Water

81. Watesal A

82. Uzushio Biryuu M

83. Chlorure De Sodium

84. Adsorbanac (tn)

85. Brinewate Superfine

86. Sodium Chloride In Plastic Container

87. Sodium Chloride Salt

88. Canners 999

89. Sodium Chloride Acs

90. Nacl Solution, 1m

91. 0.9% Saline

92. Sodium Chloride 3% In Plastic Container

93. Sodium Chloride 5% In Plastic Container

94. Suprasel Nitrite

95. 0.9% Saline Solution

96. Saline, Sodium Chloride

97. Sodium Chloride, Tablet

98. Sodium Chloride (8ci)

99. Sodium Chloride 0.9% In Plastic Container

100. Mono-sodium Chloride Salt

101. 0.9% Nacl

102. Sodium Chloride 0.45% In Plastic Container

103. Sodium Chloride 23.4% In Plastic Container

104. Sodium Chloride, Isotonic

105. Unii-vr5y7pdt5w

106. Salt (6ci,7ci)

107. Vr5y7pdt5w

108. Special Salt 100/95

109. Nacl 0.9%

110. Wln: Na G

111. Ec 231-598-3

112. Sodium Chloride [ii]

113. Sodium Chloride [mi]

114. Sodium Chloride 0.9% In Sterile Plastic Container

115. Sodium Chloride, Acs Reagent

116. B1655 [langual]

117. Sodium Chloride [jan]

118. Rns60 Component Saline

119. Sodium Chloride (jp17/usp)

120. Sodium Chloride [hsdb]

121. Sodium Chloride [inci]

122. Sodium Chloride Solution, 1 M

123. Sodium Chloride Solution, 2 M

124. Sodium Chloride, Optical Grade

125. Sodium Chloride [vandf]

126. Sodium Chloride Anhydrous

127. Bacteriostatic Sodium Chloride 0.9% In Plastic Container

128. Chembl1200574

129. Dtxsid3021271

130. Natrum Muriaticum [hpus]

131. Rns-60 Component Saline

132. Sodium Chloride Biochemical Grade

133. 7647-14-5 (solid)

134. Sodium Chloride [usp-rs]

135. Sodium Chloride [who-dd]

136. Sodium Chloride [who-ip]

137. Sodium Chloride, Anhydrous

138. Sodium Chloride Solution, 0.1 M

139. Sodium Chloride Solution, 0.85%

140. Sodium Chloride Solution, Isotonic

141. Nsc77364

142. Sodium Chloride, Ar, >=99.9%

143. Sodium Chloride, Lr, >=99.5%

144. Sodium Chloride, Spectroscopy Grade

145. Str02627

146. Sodium Chloride, Manac Incorporated

147. Sodium Chloride [green Book]

148. Sodium Chloride, >=99%, Ar Grade

149. Sodium Chloride [orange Book]

150. Akos024438089

151. Akos024457457

152. Sodium Chloride [ep Monograph]

153. Sodium Chloride, Bacteriostatic

154. 10% Sodium Chloride Solution In Water

155. Db09153

156. Sodium Chloride [usp Monograph]

157. Sodium Chloride Saturated Solution 26%

158. Sodium Chloride, Technical Grade, 95%

159. Sodium Chloride, Technical Grade, 97%

160. Natrii Chloridum [who-ip Latin]

161. Sodium Chloride, Ph. Eur., Usp Grade

162. Sodium Chloride, P.a., 99-100.5%

163. 32343-72-9

164. Chloride Standard Solution, 1 Mg/ml Cl-

165. Sodium Chloride, Nist(r) Srm(r) 919b

166. Sodium Chloride, Reagentplus(r), >=99%

167. Sodium Chloride, Usp, 99.0-100.5%

168. Sodium Chloride, Usp, 99.0-101.0%

169. B7288

170. Ft-0645114

171. Q2314

172. S0572

173. Sodium Chloride, 0.1n Standardized Solution

174. Sodium Chloride, Bioxtra, >=99.5% (at)

175. Sodium Chloride, Saj First Grade, >=99.0%

176. Sodium Chloride, Tested According To Ph.eur.

177. D02056

178. Sodium Chloride, 99.999% Trace Metals Basis

179. Sodium Chloride, Jis Special Grade, >=99.5%

180. Sodium Chloride, Trace Metals Grade, 99.99%

181. Isotopic Standard For Chlorine, Nist Srm 975a

182. Sodium Chloride, 5m Aqueous Solution, Autoclaved

183. Sodium Chloride, Vetec(tm) Reagent Grade, 99%

184. Sodanylium And Hydrochloric Acid, Ion(1-) (1:1)

185. Sodium Chloride, 5m Aqueous Solution, Rnase Free

186. Sodium Chloride, Puriss. P.a., >=99.5% (at)

187. Sodium Chloride, Nist(r) Srm(r) 2201, Ion-selective

188. Sodium Chloride Crystal Optic Disc, 13mm X 2mm, Unpolished

189. Sodium Chloride Crystal Optic Disc, 25mm X 5mm, Unpolished

190. Sodium Chloride Crystal Optic Disc, 32mm X 3mm, Unpolished

191. Sodium Chloride, 5m Aqueous Solution, Ph 8.0, Autoclaved

192. Sodium Chloride Crystal Optic Disc, 13mm X 1mm, Polished Both Sides

193. Sodium Chloride Crystal Optic Disc, 13mm X 2mm, Polished Both Sides

194. Sodium Chloride Crystal Optic Disc, 22mm X 4mm, Polished Both Sides

195. Sodium Chloride Crystal Optic Disc, 25mm X 2mm, Polished Both Sides

196. Sodium Chloride Crystal Optic Disc, 25mm X 4mm, Polished Both Sides

197. Sodium Chloride Crystal Optic Disc, 32mm X 3mm, Polished Both Sides

198. Sodium Chloride Crystal Optic Disc, 38mm X 6mm, Polished Both Sides

199. Sodium Chloride, Bioultra, For Molecular Biology, >=99.5% (at)

200. Sodium Chloride, Puriss. P.a., >=99.5% (at), Powder Or Crystals

201. Sodium Chloride, Reagent Grade, >=98%, +80 Mesh Particle Size

202. Sodium Chloride, United States Pharmacopeia (usp) Reference Standard

203. Sodium Standard For Aas, Ready-to-use, Traceable To Bam, In H2o

204. Sodium Chloride Crystal Optic Rectangle, 30mm X 15mm X 4mm, Unpolished

205. Sodium Chloride Crystal Optic Rectangle, 38.5mm X 19.5mm X 4mm, Unpolished

206. Sodium Chloride Crystal Optic Rectangle, 41mm X 23mm X 6mm, Unpolished

207. Sodium Chloride Solution, Bioultra, For Molecular Biology, ~5 M In H2o

208. Sodium Chloride Solution, Technical, ~26% (saturated In Water At 20c, At)

209. Sodium Chloride, Anhydrous, Beads, -10 Mesh, 99.99% Trace Metals Basis

210. Sodium Chloride, Anhydrous, Beads, -10 Mesh, 99.999% Trace Metals Basis

211. Sodium Chloride, P.a., Acs Reagent, Reag. Iso, Reag. Ph. Eur., 99.5%

212. Sodium Chloride, Random Crystals, Optical Grade, 99.98% Trace Metals Basis

213. Sodium Chloride Crystal Optic Disc, 32mm X 3mm (drilled), Polished Both Sides

214. Sodium Chloride Crystal Optic Rectangle, 30mm X 15mm X 4mm (drilled), Polished Both Sides

215. Sodium Chloride Crystal Optic Rectangle, 30mm X 15mm X 4mm, Polished Both Sides

216. Sodium Chloride Crystal Optic Rectangle, 38.5mm X 19.5mm X 4mm, Polished Both Sides

217. Sodium Chloride Solution, 0.9% In Water, Bioxtra, Suitable For Cell Culture

218. Sodium Chloride, Anhydrous, Free-flowing, Redi-dri(tm), Reagentplus(r), >=99%

219. Sodium Chloride, Anhydrous, Redi-dri(tm), Free-flowing, Acs Reagent, >=99%

220. Sodium Chloride, Bioperformance Certified, >=99% (titration), Cell Culture Tested

221. Sodium Chloride, Meets Analytical Specification Of Ph. Eur., Bp, Usp, 99.0-100.5%

222. Sodium Chloride, Pharmaceutical Secondary Standard; Certified Reference Material

223. Sodium Chloride, Puriss. P.a., Acs Reagent, Reag. Iso, Reag. Ph. Eur., >=99.5%

224. Sodium Atomic Spectroscopy Standard Concentrate 1.00 G Na, 1.00 G/l, For 1 L Standard Solution, Analytical Standard

225. Sodium Atomic Spectroscopy Standard Concentrate 10.00 G Na, 10.00 G/l, For 1 L Standard Solution, Analytical Standard

226. Sodium Chloride Crystal Optic Rectangle, 38.5mm X 19.5mm X 4mm (drilled), Polished Both Sides

227. Sodium Chloride Solution, 5 M In H2o, Bioreagent, For Molecular Biology, Suitable For Cell Culture

228. Sodium Chloride, Bioreagent, Suitable For Cell Culture, Suitable For Insect Cell Culture, Suitable For Plant Cell Culture, >=99%

229. Sodium Chloride, Certified Reference Material For Titrimetry, Certified By Bam, According To Iso 17025, >=99.5%

230. Sodium Chloride, For Molecular Biology, Dnase, Rnase, And Protease, None Detected, >=98% (titration)

231. Sodium Chloride, Pharmagrade, Usp, Manufactured Under Appropriate Gmp Controls For Pharma Or Biopharmaceutical Production.

232. Sodium Chloride, Puriss., Meets Analytical Specification Of Ph. Eur., Bp, Usp, 99.0-100.5% (calc. To The Dried Substance), <=0.00002% Al

233. Sodium Standard Solution, Suitable For Atomic Absorption Spectrometry, 1000 Ppm Na, 1 Mg/ml Na

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 58.44 g/mol
Molecular Formula ClNa
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass57.9586220 g/mol
Monoisotopic Mass57.9586220 g/mol
Topological Polar Surface Area0 Ų
Heavy Atom Count2
Formal Charge0
Complexity2
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameBroncho saline
PubMed HealthSodium Chloride (By breathing)
Drug ClassesAntiasthma, Respiratory Agent
Drug Label14.6% Sodium Chloride Injection, USP Additive Solution is a sterile, nonpyrogenic, concentrated solution for intravenous administration ONLY AFTER DILUTION to replenish electrolytes. The preparations contain either 2.92 or 5.84 g of sodium chloride (...
Active IngredientSodium chloride
Dosage FormAerosol, metered
RouteInhalation
Strength0.9%
Market StatusOver the Counter
CompanyBlairex

2 of 6  
Drug NameSodium chloride
PubMed HealthSodium Chloride
Drug ClassesAntiasthma, Osmotherapy Agent, Parenteral Electrolyte, Sodium, Respiratory Agent, Sodium Supplement
Active IngredientSodium chloride
Dosage FormInjectable
Routeinjection
Strength10ml
Market StatusPrescription
CompanyTaro Pharms Ireland

3 of 6  
Drug NameSodium chloride in plastic container
Active IngredientSodium chloride
Dosage FormInjectable
RouteInjection
Strength2.5meq/ml
Market StatusPrescription
CompanyHospira

4 of 6  
Drug NameBroncho saline
PubMed HealthSodium Chloride (By breathing)
Drug ClassesAntiasthma, Respiratory Agent
Drug Label14.6% Sodium Chloride Injection, USP Additive Solution is a sterile, nonpyrogenic, concentrated solution for intravenous administration ONLY AFTER DILUTION to replenish electrolytes. The preparations contain either 2.92 or 5.84 g of sodium chloride (...
Active IngredientSodium chloride
Dosage FormAerosol, metered
RouteInhalation
Strength0.9%
Market StatusOver the Counter
CompanyBlairex

5 of 6  
Drug NameSodium chloride
PubMed HealthSodium Chloride
Drug ClassesAntiasthma, Osmotherapy Agent, Parenteral Electrolyte, Sodium, Respiratory Agent, Sodium Supplement
Active IngredientSodium chloride
Dosage FormInjectable
Routeinjection
Strength10ml
Market StatusPrescription
CompanyTaro Pharms Ireland

6 of 6  
Drug NameSodium chloride in plastic container
Active IngredientSodium chloride
Dosage FormInjectable
RouteInjection
Strength2.5meq/ml
Market StatusPrescription
CompanyHospira

4.2 Therapeutic Uses

Sodium chloride injections are used as a source of sodium chloride and water for hydration. Sodium chloride is used in the prevention or treatment of deficiencies of sodium and chloride ions and in the prevention of muscle cramps and heat prostration resulting from excessive perspiration during exposure to high temperature. Sodium chloride is also used to treat deficiencies of sodium and chloride caused by excessive diuresis or excessive salt restriction.

American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2758


0.45% Sodium chloride injection is used principally as a hydrating solution and may be used to assess renal function status, since more water is provided than is required for excretion of salt. 0.45% Sodium chloride injection is also used in the management of hyperosmolar diabetes.

American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2758


0.9% Sodium chloride injection is used for extracellular fluid replacement and in the management of metabolic alkalosis in the presence of fluid loss and mild sodium depletion. 0.9% Sodium chloride injection (normal saline) is also used as a priming fluid for hemodialysis procedures and to initiate and terminate blood transfusions.

American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2758


Hypertonic (i.e., 3%, 5%) sodium chloride injection is used in the management of severe sodium chloride depletion when rapid electrolyte restoration is essential. Severe sodium chloride depletion may occur in the presence of heart failure or renal impairment, or during surgery or postoperatively. In these conditions, chloride loss often exceeds sodium loss. Hypertonic sodium chloride injections are also used in the management of hyponatremia and hypochloremia resulting from administration of sodium-free fluids during fluid and electrolyte therapy; in the management of extreme dilution of extracellular fluid following excessive water intake (e.g., that resulting from multiple enemas or perfusion of irrigating solutions into open venous sinuses during transurethral prostatic resections); and in the emergency treatment of severe sodium chloride depletion resulting from excess sweating, vomiting, diarrhea, and other conditions.

American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2758


For more Therapeutic Uses (Complete) data for SODIUM CHLORIDE (13 total), please visit the HSDB record page.


4.3 Drug Warning

Bacteriostatic sodium chloride injection containing benzyl alcohol as a preservative (antimicrobial agent) should not be used for diluting or reconstituting drugs for administration in neonates nor should it be used to flush intravascular catheters in neonates. Several deaths have been reported in neonates weighing less than 2.5 kg in whom bacteriostatic sodium chloride for injection containing 0.9% benzyl alcohol was used for flushing IV catheters; some of these neonates received additional benzyl alcohol when bacteriostatic sodium chloride injection was used to dilute or reconstitute drugs. The deaths were usually preceded by a syndrome that included metabolic acidosis, CNS depression, respiratory distress progressing to gasping respiration, hypotension, renal failure, and, occasionally, seizures and intracranial hemorrhage. High concentrations of benzyl alcohol, benzoic acid, and hippuric acid (a metabolite) were present in blood and urine in these neonates. Benzyl alcohol toxicity apparently was caused by administration of relatively large daily doses (99-404 mg/kg daily) of the preservative in proportion to the neonate's weight. Although these neonates had biochemical evidence of benzyl alcohol toxicity, they also had serious underlying conditions.

American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2759


Sodium chloride is contraindicated in patients with conditions in which administration of sodium and chloride is detrimental. Sodium chloride 3 and 5% injections are also contraindicated in the presence of increased, normal, or only slightly decreased serum electrolyte concentrations.

American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2759


Sodium chloride should be used with extreme caution, if at all, in patients with congestive heart failure or other edematous or sodium-retaining conditions, in patients with severe renal insufficiency, in patients with liver cirrhosis, and in patients receiving corticosteroids or corticotropin; particular caution is necessary in geriatric or postoperative patients. IV administration of sodium chloride may cause fluid and/or solute overload resulting in dilution of serum electrolytes, overhydration, congestive conditions, or pulmonary edema. The risk of dilutional conditions is inversely proportional to the electrolyte concentration administered, and the risk of solute overload and resultant congestive conditions with peripheral and/or pulmonary edema is directly proportional to the electrolyte concentration administered. The manufacturers warn that excessive IV administration of sodium chloride may result in hypokalemia.

American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2759


Changes in fluid balance, electrolyte concentrations, and acid-base balance should be evaluated clinically and via periodic laboratory determinations during prolonged therapy with sodium chloride and in patients whose condition warrants such evaluation. Substantial changes may require additional electrolyte supplements or other appropriate therapy. Additional electrolyte supplementation may also be required in patients with substantial electrolyte losses resulting from conditions such as protracted nasogastric suctioning, vomiting, diarrhea, or GI fistula drainage.

American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2759


For more Drug Warnings (Complete) data for SODIUM CHLORIDE (12 total), please visit the HSDB record page.


4.4 Minimum/Potential Fatal Human Dose

The estimated fatal dose of sodium chloride is approximately 0.75 to 3.00 g/kg.

Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 1057


An estimated dose of more than 400 mEq/kg resulted in brain injury and death in a 2 year old child given a salt water solution to induce emesis.

Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 1057


4.5 Drug Indication

This intravenous solution is indicated for use in adults and pediatric patients as a source of electrolytes and water for hydration. Also, designed for use as a diluent and delivery system for intermittent intravenous administration of compatible drug additives.


5 Pharmacology and Biochemistry
5.1 Pharmacology

Sodium, the major cation of the extracellular fluid, functions primarily in the control of water distribution, fluid balance, and osmotic pressure of body fluids. Sodium is also associated with chloride and bicarbonate in the regulation of the acid-base equilibrium of body fluid. Chloride, the major extracellular anion, closely follows the metabolism of sodium, and changes in the acid-base balance of the body are reflected by changes in the chloride concentration.


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]; Osmotic Laxative [EPC]; Increased Large Intestinal Motility [PE]
5.3 ATC Code

A - Alimentary tract and metabolism

A12 - Mineral supplements

A12C - Other mineral supplements

A12CA - Sodium

A12CA01 - Sodium chloride


B - Blood and blood forming organs

B05 - Blood substitutes and perfusion solutions

B05C - Irrigating solutions

B05CB - Salt solutions

B05CB01 - Sodium chloride


B - Blood and blood forming organs

B05 - Blood substitutes and perfusion solutions

B05X - I.v. solution additives

B05XA - Electrolyte solutions

B05XA03 - Sodium chloride


S - Sensory organs

S01 - Ophthalmologicals

S01X - Other ophthalmologicals

S01XA - Other ophthalmologicals

S01XA03 - Sodium chloride, hypertonic


5.4 Absorption, Distribution and Excretion

Absorption

Absorption of sodium in the small intestine plays an important role in the absorption of chloride, amino acids, glucose, and water. Chloride, in the form of hydrochloric acid (HCl), is also an important component of gastric juice, which aids the digestion and absorption of many nutrients.


Route of Elimination

Substantially excreted by the kidneys.


Volume of Distribution

The volume of distribution is 0.64 L/kg.


The primary route of sodium excretion is the urine; additional excretion occurs in sweat and feces. The kidney filters sodium a the glomerulus, but 60% to 70% is reabsorbed in the proximal tubules along with bicarbonate and water. Another 25% to 30% is reabsorbed in the loop of Henle, along with chloride and water. In the distal tubules, aldosterone modulates the reabsorption of sodium and, indirectly, chloride. The renal threshold for sodium is 110 to 130 mEq/L. Less than 1% of the filtered sodium is excreted in the urine.

Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 1057


Sodium is rapidly absorbed from the GI tract; it is also absorbed from rectal enemas. Intestinal wall absorption occurs via the Na+, K+-adenosine triphosphatase system that is augmented by aldosterone and desoxycorticosterone acetate. Sodium is not bound by plasma proteins. The volume of distribution is 0.64 L/kg.

Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 1057


In one study using radiolabeled 20% sodium chloride injection, most of the drug concentrated in the decidua and the fetal part of the placenta following intra-amniotic injection. Following intra-amniotic administration of 20% sodium chloride injection, some of the drug diffuses into the maternal blood.

American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 3323


Atrichial sweat glands ... are the organs by which considerable body water and electrolytes, mainly sodium chloride, are lost.

Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 8:69


For more Absorption, Distribution and Excretion (Complete) data for SODIUM CHLORIDE (6 total), please visit the HSDB record page.


5.5 Metabolism/Metabolites

The salt that is taken in to gastro intestinal tract remains for the most part unabsorbed as the liquid contents pass through the stomach and small bowel. On reaching the colon this salt, together with the water is taken in to the blood. As excesses are absorbed the kidney is constantly excreting sodium chloride, so that the chloride level in the blood and tissues remains fairly constant.Further more, if the chloride intake ceases, the kidney ceases to excrete chlorides. Body maintains an equilibrium retaining the 300gm of salt dissolved in the blood and fluid elements of the tissue dissociated into sodium ions and chloride ions.


5.6 Biological Half-Life

17 minutes


5.7 Mechanism of Action

Sodium and chloride major electrolytes of the fluid compartment outside of cells (i.e., extracellular) work together to control extracellular volume and blood pressure. Disturbances in sodium concentrations in the extracellular fluid are associated with disorders of water balance.


Intra-amniotic instillation of 20% sodium chloride injection induces abortion and fetal death. Although the mechanism has not been conclusively determined, some studies indicate that the drug's abortifacient activity may be mediated by prostaglandins released from decidual cells damaged by hypertonic solutions of sodium chloride. Hypertonic sodium chloride-induced uterine contractions are usually sufficient to cause evacuation of both the fetus and placenta; however, abortion may be incomplete in 25-40% of patients. /20% injection/

American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 3323


API SUPPLIERS

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Baxter Healthcare Corporation

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USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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ESCO - EUROPEAN SALT COMPANY GMBH ...

Germany

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ESCO - EUROPEAN SALT COMPANY GMBH ...

Germany

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Compamed
Not Confirmed
USDMF arrow-down CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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03

S D Fine Chem Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
Not Confirmed
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S D Fine Chem Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

arrow
Compamed
Not Confirmed
USDMF arrow-down CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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04

VM Chemicals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
Not Confirmed
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VM Chemicals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Compamed
Not Confirmed
USDMF arrow-down CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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05

Nandu Chemicals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
Not Confirmed
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Nandu Chemicals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Compamed
Not Confirmed
USDMF arrow-down CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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06

Nandu Chemicals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
Not Confirmed
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Nandu Chemicals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

arrow
Compamed
Not Confirmed
USDMF arrow-down CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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07

Irvine Scientific Sales Company

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
Not Confirmed
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Irvine Scientific Sales Company

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Compamed
Not Confirmed
USDMF arrow-down CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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08

India Phosphate

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
Not Confirmed
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India Phosphate

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Compamed
Not Confirmed
USDMF arrow-down CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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09

Luitpold Pharmaceuticals, Inc.

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
Not Confirmed
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Luitpold Pharmaceuticals, Inc.

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

arrow
Compamed
Not Confirmed
USDMF Inactive-api CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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10

Luitpold Pharmaceuticals, Inc.

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Compamed
Not Confirmed
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Luitpold Pharmaceuticals, Inc.

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

arrow
Compamed
Not Confirmed
USDMF Inactive-api CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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API Reference Price

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HEATHROW","customer":"RECKITT BENCKISER HEALTHCARE","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"2","totalValueFC":"1120.4","currency":"GBP","unitRateINR":"307.3","date":"17-May-2023","totalValueINR":"92191.14","totalValueInUsd":"1120.4","indian_port":"DELHI AIR","hs_no":"29251100","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"Denmark","selfForZScoreResived":"Pharma Grade","supplierPort":"LONDON HEATHROW","supplierAddress":"","customerAddress":"PLOT NO 48 SECTOR 32, NEAR INSTITU, TIONAL AREA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1694370600,"product":"GLUCOSAMINE SULPHATE SODIUM CHLORIDE USP","address":"NO.7-2-C8 & C8\/2 G V CHAMBERS,SANA","city":"HYDERABAD,TELANGANA","supplier":"JIAXING HENGJIE BIOPHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"EVERTOGEN LIFE SCIENCES ","customerCountry":"INDIA","quantity":"1500.00","actualQuantity":"1500","unit":"KGS","unitRateFc":"5.5","totalValueFC":"8343.6","currency":"USD","unitRateINR":"461.7","date":"11-Sep-2023","totalValueINR":"692588","totalValueInUsd":"8343.6","indian_port":"SEZ\/Mahaboobnagar","hs_no":"29420090","bill_no":"1002568","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"N\/A","customerAddress":"NO.7-2-C8 & C8\/2 G V CHAMBERS,SANA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1702060200,"product":"GLUCOSAMINE SULPHATE SODIUM CHLORIDE USP","address":"NO.7-2-C8 & C8\/2 G V CHAMBERS,SANA","city":"HYDERABAD,TELANGANA","supplier":"JIAXING HENGJIE BIOPHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"EVERTOGEN LIFE SCIENCES ","customerCountry":"INDIA","quantity":"1750.00","actualQuantity":"1750","unit":"KGS","unitRateFc":"23.5","totalValueFC":"41647.1","currency":"USD","unitRateINR":"1981.1","date":"09-Dec-2023","totalValueINR":"3466838","totalValueInUsd":"41647.1","indian_port":"SEZ\/Mahaboobnagar","hs_no":"29420090","bill_no":"1003440","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"N\/A","customerAddress":"NO.7-2-C8 & C8\/2 G V CHAMBERS,SANA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1705602600,"product":"GLUCOSAMINE SULPHATE SODIUM CHLORIDE USP","address":"NO.7-2-C8 & C8\/2 G V CHAMBERS,SANA","city":"HYDERABAD,TELANGANA","supplier":"JIAXING HENGJIE BIOPHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"EVERTOGEN LIFE SCIENCES ","customerCountry":"INDIA","quantity":"1500.00","actualQuantity":"1500","unit":"KGS","unitRateFc":"5.5","totalValueFC":"8348.1","currency":"USD","unitRateINR":"462.6","date":"19-Jan-2024","totalValueINR":"693825","totalValueInUsd":"8348.1","indian_port":"SEZ\/Mahaboobnagar","hs_no":"29329990","bill_no":"1000158","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"N\/A","customerAddress":"NO.7-2-C8 & C8\/2 G V CHAMBERS,SANA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1714761000,"product":"GLUCOSAMINE SULPHATE SODIUM CHLORIDE USP","address":"NO.7-2-C8 & C8\/2 G V CHAMBERS,SANA","city":"HYDERABAD,TELANGANA","supplier":"JIAXING HENGJIE BIOPHARMACEUTICAL CO., LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"EVERTOGEN LIFE SCIENCES ","customerCountry":"INDIA","quantity":"1300.00","actualQuantity":"1300","unit":"KGS","unitRateFc":"27.9","totalValueFC":"36683.1","currency":"USD","unitRateINR":"2352.1","date":"04-May-2024","totalValueINR":"3057688","totalValueInUsd":"36683.1","indian_port":"SEZ\/Mahaboobnagar","hs_no":"29420090","bill_no":"1001423","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO.20 TONGYI ROAD, XINFENG INDUSTRI AL PARK, JIAXING, ZHEJIANG, 314001 CHINA","customerAddress":"NO.7-2-C8 & C8\/2 G V CHAMBERS,SANA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717785000,"product":"GLUCOSAMINE SULPHATE SODIUM CHLORIDE USP","address":"NO.7-2-C8 & C8\/2 G V CHAMBERS,SANA","city":"HYDERABAD,TELANGANA","supplier":"JIAXING HENGJIE BIOPHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"EVERTOGEN LIFE SCIENCES ","customerCountry":"INDIA","quantity":"4000.00","actualQuantity":"4000","unit":"KGS","unitRateFc":"21.3","totalValueFC":"85835.5","currency":"USD","unitRateINR":"1791.4","date":"08-Jun-2024","totalValueINR":"7165500","totalValueInUsd":"85835.5","indian_port":"SEZ\/Mahaboobnagar","hs_no":"29420090","bill_no":"1001821","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"N\/A","customerAddress":"NO.7-2-C8 & C8\/2 G V CHAMBERS,SANA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725474600,"product":"GLUCOSAMINE SULFATE SODIUM CHLORIDE USP (D-GLUCOSAMINE SULPHATE 2 NA CL) (RE-IMPORT)","address":"UNIT NOP.203\/234,ANANDRAJ INDL.","city":"BHANDUP (W) MAHARASHTRA","supplier":"ASOFARMA DE MEXICO SA DE CV","supplierCountry":"INDIA","foreign_port":"MANZANILLO","customer":"CHEMPIFINE CHEMICALS","customerCountry":"INDIA","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"12","totalValueFC":"12449.9","currency":"USD","unitRateINR":"1043.3","date":"05-Sep-2024","totalValueINR":"1043316.23","totalValueInUsd":"12449.9","indian_port":"JNPT","hs_no":"29420090","bill_no":"5446154","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"MANZANILLO","supplierAddress":"CALZ. MEXICO XOCHIMILCO NO. 43 COL. SAN LORENZO HUIPULCO 14370 CIUDAD DE MEXICO MEXICO MEXICO MEXICO","customerAddress":"UNIT NOP.203\/234,ANANDRAJ INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725474600,"product":"GLUCOSAMINE SULFATE SODIUM CHLORIDE USP (D-GLUCOSAMINE SULPHATE 2 NA CL)(RE-IMPORT)","address":"UNIT NOP.203\/234,ANANDRAJ INDL.","city":"BHANDUP (W) MAHARASHTRA","supplier":"ASOFARMA DE MEXICO SA DE CV","supplierCountry":"INDIA","foreign_port":"MANZANILLO","customer":"CHEMPIFINE CHEMICALS","customerCountry":"INDIA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"12","totalValueFC":"622.5","currency":"USD","unitRateINR":"1043.3","date":"05-Sep-2024","totalValueINR":"52165.81","totalValueInUsd":"622.5","indian_port":"JNPT","hs_no":"29420090","bill_no":"5446154","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"MANZANILLO","supplierAddress":"CALZ. MEXICO XOCHIMILCO NO. 43 COL. SAN LORENZO HUIPULCO 14370 CIUDAD DE MEXICO MEXICO MEXICO MEXICO","customerAddress":"UNIT NOP.203\/234,ANANDRAJ INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725474600,"product":"GLUCOSAMINE SULFATE SODIUM CHLORIDE USP (D-GLUCOSAMINE SULPHATE 2 NA CL) (RE-IMPORT)","address":"1004, FILIX, LBS MARG, BHANDUP","city":"MUMBAI","supplier":"ASOFARMA DE MEXICO SA DE CV","supplierCountry":"INDIA","foreign_port":"MANZANILLO","customer":"FELIX PHARMA LABS","customerCountry":"INDIA","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"12","totalValueFC":"12441.9","currency":"USD","unitRateINR":"1042.6","date":"05-Sep-2024","totalValueINR":"1042645.29","totalValueInUsd":"12441.9","indian_port":"JNPT","hs_no":"29420090","bill_no":"5436232","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"MANZANILLO","supplierAddress":"CALZ. MEXICO XOCHIMILCO NO.43 COL. SAN LORENZO HUIPULCO 14370 CIUDAD DE MEXICO MEXICO , MEXICO MEXICO","customerAddress":"1004, FILIX, LBS MARG, BHANDUP"}]
13-Jan-2021
05-Sep-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - INJECTABLE;INJECTION - 900MG/100ML

USFDA APPLICATION NUMBER - 16366

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DOSAGE - SOLUTION;INJECTION - 225MG/25ML (9MG...DOSAGE - SOLUTION;INJECTION - 225MG/25ML (9MG/ML)

USFDA APPLICATION NUMBER - 16677

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DOSAGE - SOLUTION;INJECTION - 450MG/50ML (9MG...DOSAGE - SOLUTION;INJECTION - 450MG/50ML (9MG/ML)

USFDA APPLICATION NUMBER - 16677

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DOSAGE - SOLUTION;INJECTION - 900MG/100ML

USFDA APPLICATION NUMBER - 16677

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DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;30...DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;30MG/100ML;600MG/100ML;310MG/100ML

USFDA APPLICATION NUMBER - 16682

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DOSAGE - SOLUTION;IRRIGATION - 900MG/100ML

USFDA APPLICATION NUMBER - 16733

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DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/100ML;1.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 17512

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DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/100ML;2.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 17512

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DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/100ML;3.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 17512

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DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/100ML;4.25GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 17512

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;1.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 17512

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;2.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 17512

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;3.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 17512

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;4.25GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 17512

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DOSAGE - SOLUTION;IRRIGATION - 900MG/100ML

USFDA APPLICATION NUMBER - 17514

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;900...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;900MG/100ML

USFDA APPLICATION NUMBER - 17585

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;225...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;225MG/100ML

USFDA APPLICATION NUMBER - 17606

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;450...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;450MG/100ML

USFDA APPLICATION NUMBER - 17607

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DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5G...DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;30MG/100ML;600MG/100ML;310MG/100ML

USFDA APPLICATION NUMBER - 17608

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;300...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;300MG/100ML

USFDA APPLICATION NUMBER - 17799

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DOSAGE - INJECTABLE;INJECTION - 450MG/100ML

USFDA APPLICATION NUMBER - 18016

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DOSAGE - INJECTABLE;INJECTION - 450MG/100ML

USFDA APPLICATION NUMBER - 18090

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;149...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;149MG/100ML;450MG/100ML

USFDA APPLICATION NUMBER - 18362

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;224...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;224MG/100ML;450MG/100ML

USFDA APPLICATION NUMBER - 18362

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;298...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;298MG/100ML;450MG/100ML

USFDA APPLICATION NUMBER - 18362

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;74....DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;74.5MG/100ML;450MG/100ML

USFDA APPLICATION NUMBER - 18362

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;149...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;149MG/100ML;225MG/100ML

USFDA APPLICATION NUMBER - 18365

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;298...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;298MG/100ML;225MG/100ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 18365

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;74....DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;74.5MG/100ML;225MG/100ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 18365

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DOSAGE - SOLUTION;IRRIGATION - 0.154MG/ML;0.9...DOSAGE - SOLUTION;IRRIGATION - 0.154MG/ML;0.92MG/ML;0.184MG/ML;0.2MG/ML;0.38MG/ML;2.1MG/ML;7.14MG/ML;0.42MG/ML

USFDA APPLICATION NUMBER - 18469

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DOSAGE - SOLUTION;INJECTION - 180MG/20ML (9MG...DOSAGE - SOLUTION;INJECTION - 180MG/20ML (9MG/ML)

USFDA APPLICATION NUMBER - 18800

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DOSAGE - SOLUTION;INJECTION - 270MG/30ML (9MG...DOSAGE - SOLUTION;INJECTION - 270MG/30ML (9MG/ML)

USFDA APPLICATION NUMBER - 18800

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DOSAGE - SOLUTION;INJECTION - 90MG/10ML (9MG/...DOSAGE - SOLUTION;INJECTION - 90MG/10ML (9MG/ML)

USFDA APPLICATION NUMBER - 18800

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DOSAGE - SOLUTION;INJECTION - 180MG/20ML (9MG...DOSAGE - SOLUTION;INJECTION - 180MG/20ML (9MG/ML)

USFDA APPLICATION NUMBER - 18803

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DOSAGE - SOLUTION;INJECTION - 18MG/2ML (9MG/M...DOSAGE - SOLUTION;INJECTION - 18MG/2ML (9MG/ML)

USFDA APPLICATION NUMBER - 18803

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DOSAGE - SOLUTION;INJECTION - 27MG/3ML (9MG/M...DOSAGE - SOLUTION;INJECTION - 27MG/3ML (9MG/ML)

USFDA APPLICATION NUMBER - 18803

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DOSAGE - SOLUTION;INJECTION - 450MG/50ML (9MG...DOSAGE - SOLUTION;INJECTION - 450MG/50ML (9MG/ML)

USFDA APPLICATION NUMBER - 18803

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DOSAGE - SOLUTION;INJECTION - 45MG/5ML (9MG/M...DOSAGE - SOLUTION;INJECTION - 45MG/5ML (9MG/ML)

USFDA APPLICATION NUMBER - 18803

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DOSAGE - SOLUTION;INJECTION - 90MG/10ML (9MG/...DOSAGE - SOLUTION;INJECTION - 90MG/10ML (9MG/ML)

USFDA APPLICATION NUMBER - 18803

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;1.5GM/100ML;15.2MG/100ML;567MG/100ML;392MG/100ML

USFDA APPLICATION NUMBER - 18883

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;1.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 18883

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;2.5GM/100ML;15.2MG/100ML;567MG/100ML;392MG/100ML

USFDA APPLICATION NUMBER - 18883

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;2.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 18883

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;4.25GM/100ML;15.2MG/100ML;567MG/100ML;392MG/100ML

USFDA APPLICATION NUMBER - 18883

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;4.25GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 18883

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DOSAGE - SOLUTION;IRRIGATION - 20MG/100ML;30M...DOSAGE - SOLUTION;IRRIGATION - 20MG/100ML;30MG/100ML;600MG/100ML;310MG/100ML

USFDA APPLICATION NUMBER - 19416

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DOSAGE - INJECTABLE;INJECTION - 450MG/100ML

USFDA APPLICATION NUMBER - 19635

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DOSAGE - INJECTABLE;INJECTION - 900MG/100ML

USFDA APPLICATION NUMBER - 19635

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DOSAGE - SOLUTION;INJECTION - 90MG/10ML (9MG/...DOSAGE - SOLUTION;INJECTION - 90MG/10ML (9MG/ML)

USFDA APPLICATION NUMBER - 19635

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DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5G...DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;104MG/100ML;600MG/100ML;310MG/100ML

USFDA APPLICATION NUMBER - 19685

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DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5G...DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;179MG/100ML;600MG/100ML;310MG/100ML

USFDA APPLICATION NUMBER - 19685

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DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5G...DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;254MG/100ML;600MG/100ML;310MG/100ML

USFDA APPLICATION NUMBER - 19685

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DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5G...DOSAGE - INJECTABLE;INJECTION - 20MG/100ML;5GM/100ML;328MG/100ML;600MG/100ML;310MG/100ML

USFDA APPLICATION NUMBER - 19685

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;149...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;149MG/100ML;900MG/100ML

USFDA APPLICATION NUMBER - 19691

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;224...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;224MG/100ML;900MG/100ML

USFDA APPLICATION NUMBER - 19691

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;298...DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;298MG/100ML;900MG/100ML

USFDA APPLICATION NUMBER - 19691

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DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;74....DOSAGE - INJECTABLE;INJECTION - 5GM/100ML;74.5MG/100ML;900MG/100ML

USFDA APPLICATION NUMBER - 19691

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DOSAGE - FOR SOLUTION;ORAL - 420GM/BOT;1.48GM...DOSAGE - FOR SOLUTION;ORAL - 420GM/BOT;1.48GM/BOT;5.72GM/BOT;11.2GM/BOT

USFDA APPLICATION NUMBER - 19797

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;1.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 20163

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;2.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 20163

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DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 25.7MG/100ML;4.25GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 20163

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DOSAGE - SOLUTION;INTRAPERITONEAL - 18.4MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 18.4MG/100ML;1.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 20171

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DOSAGE - SOLUTION;INTRAPERITONEAL - 18.4MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 18.4MG/100ML;2.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 20171

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DOSAGE - SOLUTION;INTRAPERITONEAL - 18.4MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 18.4MG/100ML;4.25GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 20171

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DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/100ML;1.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 20183

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DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/100ML;2.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 20183

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DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/100ML;3.5GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 20183

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DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/10...DOSAGE - SOLUTION;INTRAPERITONEAL - 18.3MG/100ML;4.25GM/100ML;5.08MG/100ML;538MG/100ML;448MG/100ML

USFDA APPLICATION NUMBER - 20183

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DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML...DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML;3.05GM/1000ML;0.314GM/1000ML ;3.09GM/1000ML;6.34GM/1000ML;0.187GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 207026

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DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;3....DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;6.95GM/1000ML;0.187GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 207026

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DOSAGE - SOLUTION;IRRIGATION - 0.48MG/ML;0.3M...DOSAGE - SOLUTION;IRRIGATION - 0.48MG/ML;0.3MG/ML;0.75MG/ML;3.9MG/ML;6.4MG/ML;1.7MG/ML

USFDA APPLICATION NUMBER - 20742

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DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML...DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;7.07GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 21703

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DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML...DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.314GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 21703

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DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML...DOSAGE - INJECTABLE;INJECTION - 3.68GM/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;N/A/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 21703

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DOSAGE - INJECTABLE;INJECTION - 5.15GM/1000ML...DOSAGE - INJECTABLE;INJECTION - 5.15GM/1000ML;20GM/1000ML;5.4GM/1000ML;2.03GM/1000ML;0.157GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 21703

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DOSAGE - INJECTABLE;INJECTION - 5.15GM/1000ML...DOSAGE - INJECTABLE;INJECTION - 5.15GM/1000ML;N/A/1000ML;5.4GM/1000ML;2.03GM/1000ML;N/A/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 21703

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DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;20...DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;2.03GM/1000ML;0.157GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 21703

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DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;20...DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;2.44GM/1000ML;0.314GM/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 21703

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DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;20...DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.157GM/1000ML;2.21GM/1000ML;7.07GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 21703

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DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;20...DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;20GM/1000ML;5.4GM/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;7.07GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 21703

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DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;N/...DOSAGE - INJECTABLE;INJECTION - N/A/1000ML;N/A/1000ML;5.4GM/1000ML;2.44GM/1000ML;N/A/1000ML;3.09GM/1000ML;6.46GM/1000ML (5000ML)

USFDA APPLICATION NUMBER - 21703

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