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Also known as: 302-95-4, Deoxycholic acid sodium salt, Sodium desoxycholate, Deoxycholate sodium, Desoxycholate sodium, Sodium 7-deoxycholate
Molecular Formula
C24H39NaO4
Molecular Weight
414.6  g/mol
InChI Key
FHHPUSMSKHSNKW-SMOYURAASA-M
FDA UNII
436LS6U35Y

Sodium Deoxycholate
A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
1 2D Structure

Sodium Deoxycholate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
2.1.2 InChI
InChI=1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
2.1.3 InChI Key
FHHPUSMSKHSNKW-SMOYURAASA-M
2.1.4 Canonical SMILES
CC(CCC(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+]
2.1.5 Isomeric SMILES
C[C@H](CCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]
2.2 Other Identifiers
2.2.1 UNII
436LS6U35Y
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 12beta-isomer Deoxycholic Acid

2. 3beta-isomer Deoxycholic Acid

3. 5alpha-isomer Deoxycholic Acid

4. Choleic Acid

5. Deoxycholate

6. Deoxycholate, Sodium

7. Deoxycholic Acid

8. Deoxycholic Acid, 12beta Isomer

9. Deoxycholic Acid, 12beta-isomer

10. Deoxycholic Acid, 3beta Isomer

11. Deoxycholic Acid, 3beta-isomer

12. Deoxycholic Acid, 5alpha Isomer

13. Deoxycholic Acid, 5alpha-isomer

14. Deoxycholic Acid, Disodium Salt

15. Deoxycholic Acid, Magnesium (2:1) Salt

16. Deoxycholic Acid, Monoammonium Salt

17. Deoxycholic Acid, Monopotassium Salt

18. Deoxycholic Acid, Monosodium Salt

19. Deoxycholic Acid, Sodium Salt, 12beta-isomer

20. Desoxycholic Acid

21. Dihydroxycholanoic Acid

22. Kybella

23. Lagodeoxycholic Acid

2.3.2 Depositor-Supplied Synonyms

1. 302-95-4

2. Deoxycholic Acid Sodium Salt

3. Sodium Desoxycholate

4. Deoxycholate Sodium

5. Desoxycholate Sodium

6. Sodium 7-deoxycholate

7. Sodium Deoxycholic Acid

8. Deoxycholic Acid, Sodium Salt

9. Chebi:9177

10. 3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-oic Acid Sodium Salt

11. 436ls6u35y

12. Kybella

13. Ncgc00091038-01

14. Atx 101

15. Cholan-24-oic Acid, 3,12-dihydroxy-, Monosodium Salt, (3a,5b,12a)-

16. Dsstox_cid_13389

17. Dsstox_rid_79069

18. Dsstox_gsid_33389

19. Na-desoxycholat

20. Mfcd00064139

21. Na-desoxycholat [german]

22. Sodiumdeoxycholate

23. 3,12-dihydroxy-cholan-24-oic Acid Monosodium Salt, (3-alpha,5-beta,12-alpha)- (9ci)

24. Cas-302-95-4

25. Sodium (4r)-4-[(3r,5r,8r,9s,10s,12s,13r,14s,17r)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoate

26. Ccris 655

27. Einecs 206-132-7

28. Sodium (3alpha,5beta,12alpha)-3,12-dihydroxycholan-24-oate

29. Dihydroxy 3-12 Cholanate De Na [french]

30. Unii-436ls6u35y

31. Dihydroxy 3-12 Cholanate De Na

32. Natrium-3-alpha,12-alpha-dihydroxycholanat [german]

33. Deoxycholic Acid Sodium

34. Sodium 3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-oate

35. Natrium-3-alpha,12-alpha-dihydroxycholanat

36. Schembl37482

37. Mls002695906

38. Chembl1365278

39. Dtxsid5033389

40. Hy-n0593a

41. Sodium Desoxycholate [ii]

42. Sodium Deoxycholate [inci]

43. Tox21_111066

44. Tox21_200896

45. 5-beta-cholan-24-oic Acid, 3-alpha,12-alpha-dihydroxy-, Sodium Salt

46. Akos002391107

47. Akos017345123

48. Cs-8046

49. Nsc 681065

50. 3,12-dihydroxy-cholan-24-oic Acid Monosodium Salt, (3-alpha,5-beta,12-alpha)-

51. Cholan-24-oic Acid, 3,12-dihydroxy-, Monosodium Salt, (3-alpha,5-beta,12-alpha)-

52. Cholan-24-oic Acid, 3,12-dihydroxy-, Monosodium Salt, (3alpha,5beta,12alpha)-

53. Ncgc00258450-01

54. Ac-24206

55. Bp-31018

56. Smr001562102

57. Sodium Deoxycholate, >=97% (titration)

58. Deoxycholic Acid Sodium Salt, For Electrophoresis

59. Q-200935

60. Q25474151

61. Sodium 3alpha,12alpha-dihydroxy-5beta-cholan-24-oate

62. Sodium Deoxycholate, Vetec(tm) Reagent Grade, >=97%

63. Sodium Deoxycholate, Bioxtra, >=98.0% (dry Matter, Nt)

64. 3-.alpha.,12-.alpha.-dihydroxy-5-.beta.-cholan-24-oic Acid Sodium Salt

65. Sodium Deoxycholate, Suitable For Manufacturing Of Diagnostic Kits And Reagents

66. Sodium Deoxycholate, Pharmagrade, Manufactured Under Appropriate Controls For Use As A Raw Material In Pharma Or Biopharmaceutical Production

67. Sodium;(4r)-4-[(3r,5r,10s,12s,13r,17r)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoate

68. Sodium;(4r)-4-[(3r,5r,8r,9s,10s,12s,13r,14s,17r)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 414.6 g/mol
Molecular Formula C24H39NaO4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass414.27460400 g/mol
Monoisotopic Mass414.27460400 g/mol
Topological Polar Surface Area80.6 Ų
Heavy Atom Count29
Formal Charge0
Complexity612
Isotope Atom Count0
Defined Atom Stereocenter Count10
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Cholagogues and Choleretics

Gastrointestinal agents that stimulate the flow of bile into the duodenum (cholagogues) or stimulate the production of bile by the liver (choleretic). (See all compounds classified as Cholagogues and Choleretics.)


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16-Feb-2021
23-Dec-2024
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ABOUT THIS PAGE

Sodium Deoxycholate Manufacturers

A Sodium Deoxycholate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sodium Deoxycholate, including repackagers and relabelers. The FDA regulates Sodium Deoxycholate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sodium Deoxycholate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Sodium Deoxycholate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Sodium Deoxycholate Suppliers

A Sodium Deoxycholate supplier is an individual or a company that provides Sodium Deoxycholate active pharmaceutical ingredient (API) or Sodium Deoxycholate finished formulations upon request. The Sodium Deoxycholate suppliers may include Sodium Deoxycholate API manufacturers, exporters, distributors and traders.

click here to find a list of Sodium Deoxycholate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sodium Deoxycholate USDMF

A Sodium Deoxycholate DMF (Drug Master File) is a document detailing the whole manufacturing process of Sodium Deoxycholate active pharmaceutical ingredient (API) in detail. Different forms of Sodium Deoxycholate DMFs exist exist since differing nations have different regulations, such as Sodium Deoxycholate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Sodium Deoxycholate DMF submitted to regulatory agencies in the US is known as a USDMF. Sodium Deoxycholate USDMF includes data on Sodium Deoxycholate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Sodium Deoxycholate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Sodium Deoxycholate suppliers with USDMF on PharmaCompass.

Sodium Deoxycholate CEP

A Sodium Deoxycholate CEP of the European Pharmacopoeia monograph is often referred to as a Sodium Deoxycholate Certificate of Suitability (COS). The purpose of a Sodium Deoxycholate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Sodium Deoxycholate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Sodium Deoxycholate to their clients by showing that a Sodium Deoxycholate CEP has been issued for it. The manufacturer submits a Sodium Deoxycholate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Sodium Deoxycholate CEP holder for the record. Additionally, the data presented in the Sodium Deoxycholate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Sodium Deoxycholate DMF.

A Sodium Deoxycholate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Sodium Deoxycholate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Sodium Deoxycholate suppliers with CEP (COS) on PharmaCompass.

Sodium Deoxycholate GMP

Sodium Deoxycholate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sodium Deoxycholate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sodium Deoxycholate GMP manufacturer or Sodium Deoxycholate GMP API supplier for your needs.

Sodium Deoxycholate CoA

A Sodium Deoxycholate CoA (Certificate of Analysis) is a formal document that attests to Sodium Deoxycholate's compliance with Sodium Deoxycholate specifications and serves as a tool for batch-level quality control.

Sodium Deoxycholate CoA mostly includes findings from lab analyses of a specific batch. For each Sodium Deoxycholate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sodium Deoxycholate may be tested according to a variety of international standards, such as European Pharmacopoeia (Sodium Deoxycholate EP), Sodium Deoxycholate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sodium Deoxycholate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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