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ACTIVE PHARMA INGREDIENTS

5 API Suppliers, 5 USDMF

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5 USDMF

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29 FDF Dossiers, 26 FDA Orange Book, 2 Europe, 1 Canada

29 FDF Dossiers
26 FDA Orange Book
2 Europe
1 Canada

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Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

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API REF. PRICE (USD/KG)

$ 0

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FDF

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FDA Orange Book

Europe

Canada

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DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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USP

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US Patents

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Health Canada Patents

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Data Compilation #PharmaFlow

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Chemistry

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Also known as: Sodium fluoride f 18, Sodium fluoride-18f, 22554-99-0, Sodium fluoride (na18f), Fluorine f 18 sodium fluoride, Sodium;fluorine-18(1-)

Molecular Formula

FNa

Molecular Weight

40.990707 g/mol

InChI Key

PUZPDOWCWNUUKD-ULWFUOSBSA-M

FDA UNII

9L75099X6R

Sodium Fluoride F-18 is a radiopharmaceutical consisting of the sodium salt of fluorine F 18 fluoride with radioisotopic and bone mineralizing activities. Fluoride binds to calcium ions in hydroxyapatite crystals in bone. The uptake and incorporation of positron-emitting fluorine F 18 fluoride into bone can be imaged using positron emission tomography (PET) or single-photon emission computed tomography (SPECT), allowing visualization of malignant bone lesions in which regional blood flow and bone turnover are increased.

1 2D Structure

Sodium Fluoride 18F

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

sodium;fluorine-18(1-)

2.1.2 InChI

InChI=1S/FH.Na/h1H;/q;+1/p-1/i1-1;

2.1.3 InChI Key

PUZPDOWCWNUUKD-ULWFUOSBSA-M

2.1.4 Canonical SMILES

[F-].[Na+]

2.1.5 Isomeric SMILES

[18F-].[Na+]

2.2 Other Identifiers

2.2.1 UNII

9L75099X6R

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. Sodium Fluoride F 18

2. Sodium Fluoride-18f

3. 22554-99-0

4. Sodium Fluoride (na18f)

5. Fluorine F 18 Sodium Fluoride

6. Sodium;fluorine-18(1-)

7. Sodium Radiofluoride

8. Sodium Fluoride, F-18

9. Sodium Fluoride (18f)

10. Sodium Fluoride F 18 [usp]

11. 9l75099x6r

12. Sodium Fluoride F 18 (usp)

13. Sodium 18f-fluoride

14. Sodium Fluoride (f18)

15. 18f-naf

16. F-18 Naf

17. Unii-9l75099x6r

18. Fluorine 18-labeled Sodium Fluoride

19. Fluorine, F-18

20. Fluorine F-18 (tn)

21. Chembl1200744

22. Dtxsid001027605

23. Nsc749126

24. Nsc-749126

25. Sodium Fluoride (18f) [who-dd]

26. Sodium Fluoride F 18 [usp Impurity]

27. Sodium Fluoride F-18 [orange Book]

28. D05860

29. Q27272701

30. Radiolabeled Fluorine-18 Sodium Fluoride (18f-naf)

2.4 Create Date

2008-02-05

3 Chemical and Physical Properties

Molecular Formula	FNa
Molecular Weight	40.990707 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	40.990707 g/mol
Monoisotopic Mass	40.990707 g/mol
Topological Polar Surface Area	0 Å²
Heavy Atom Count	2
Formal Charge	0
Complexity	2
Isotope Atom Count	1
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2