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Chemistry

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Also known as: Hyaluronic acid, sodium salt, Hyaluronic acid sodium, Kopuron, Healon, Hyalgan, Hyalurone sodium
Molecular Formula
C28H44N2NaO23+
Molecular Weight
799.6  g/mol
InChI Key
YWIVKILSMZOHHF-QJZPQSOGSA-N

Sodium Hyaluronate
A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.
1 2D Structure

Sodium Hyaluronate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;(2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
2.1.2 InChI
InChI=1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1
2.1.3 InChI Key
YWIVKILSMZOHHF-QJZPQSOGSA-N
2.1.4 Canonical SMILES
CC(=O)NC1C(C(C(OC1O)CO)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)C(=O)O)O)O)O)NC(=O)C)O)O.[Na+]
2.1.5 Isomeric SMILES
CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)NC(=O)C)O)O.[Na+]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Acid, Hyaluronic

2. Amo Vitrax

3. Amvisc

4. Biolon

5. Etamucine

6. Healon

7. Hyaluronate Sodium

8. Hyaluronate, Sodium

9. Hyaluronic Acid

10. Hyvisc

11. Luronit

12. Vitrax, Amo

2.2.2 Depositor-Supplied Synonyms

1. Hyaluronic Acid, Sodium Salt

2. Hyaluronic Acid Sodium

3. Kopuron

4. Healon

5. Hyalgan

6. Hyalurone Sodium

7. 6-[3-acetamido-2-[6-[3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic Acid

8. Sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic Acid

9. Equron (veterinary)

10. Synacid (veterinary)

11. Arthrease

12. Cystistat

13. Hyalart

14. Hyalein

15. Hyalovet

16. Hyladerm

17. Khionat

18. Monovisc

19. Nidelon

20. Orthovisc

21. Ostenil

22. Provisc

23. Sinovial

24. Supartz

25. Suvenyl

26. Hyasol

27. Hyladerm Khionat

28. Nrd101

29. Ha

30. Hyaluronsan Ha-lq

31. Bio Hyaluro 12

32. Euflexxa Injection

33. Euflexxa

34. Ccris 4127

35. Hyaluronate Sodium [usan:jan]

36. Sodium Hyaluronate Hmw

37. Unii-yse9ppt4th

38. Si-4402

39. Sl-1010

40. Synacid

41. Equron

42. Chlamyhyaluronic Acid Sodium Salt

43. Sl 1010

44. Hyalauronic Acid 99%

45. Yse9ppt4th

46. Gtpl4954

47. Sodium Hyaluronate (food Grade)

48. Sodium Hyaluronate (cosmetic Grade)

49. Akos015896610

50. Sodium Hyaluronate, Low Molecular Weight

51. Sodium Hyaluronate, High Molecular Weight

52. Q27078001

53. (3s,4r,5r,6r)-3-[(2s,3r,5s,6r)-3-acetamido-4-[(2s,3r,4s,6s)-6-carboxy-3,4,5-trihydroxy-tetrahydropyran-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-6-[(3r,4r,5s,6r)-3-acetamido-2,5-dih

54. Sodium (2s,3s,4r,5r,6r)-3-{[(2s,3r,4r,5s,6r)-4-{[(2r,3r,4s,5s,6s)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-{[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-4,5-dihydroxyoxane-2-carboxylic Acid

2.3 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 799.6 g/mol
Molecular Formula C28H44N2NaO23+
Hydrogen Bond Donor Count14
Hydrogen Bond Acceptor Count23
Rotatable Bond Count12
Exact Mass799.22325494 g/mol
Monoisotopic Mass799.22325494 g/mol
Topological Polar Surface Area400 Ų
Heavy Atom Count54
Formal Charge1
Complexity1300
Isotope Atom Count0
Defined Atom Stereocenter Count20
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adjuvants, Immunologic

Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. (See all compounds classified as Adjuvants, Immunologic.)


Viscosupplements

Viscoelastic solutions that are injected into JOINTS in order to alleviate symptoms of joint-related disorders such as OSTEOARTHRITIS. (See all compounds classified as Viscosupplements.)


4.2 FDA Pharmacological Classification
4.2.1 Pharmacological Classes
Vitamin B 6 [Chemical/Ingredient]; Vitamin B6 Analog [EPC]; Analogs/Derivatives [Chemical/Ingredient]

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CEP 2021-220 - Rev 02
Valid
Chemical
2024-06-12
1472
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Certificate Number : CEP 2021-220 - Rev 02

Status : Valid

Issue Date : 2024-06-12

Type : Chemical

Substance Number : 1472

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R0-CEP 2021-446 - Rev 01
Valid
Chemical
2023-06-15
1472
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Certificate Number : R0-CEP 2021-446 - Rev 01

Status : Valid

Issue Date : 2023-06-15

Type : Chemical

Substance Number : 1472

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KDMF

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Virtual BoothBloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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Sodium hyaluronate

Registrant Name : MFC Corporation

Registration Date : 2019-11-11

Registration Number : 20130322-96-E-109-34(B)

Manufacturer Name : Bloomage Biotechnology Corp....

Manufacturer Address : No.678, Tianchen St., High-Tech Development Zone, Jinan, city, Shandong Province Chin...

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Virtual BoothBloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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Sodium hyaluronate

Registrant Name : Unimed Pharmaceutical Co., Ltd.

Registration Date : 2022-09-02

Registration Number : 20211021-96-E-171-54(2)

Manufacturer Name : Bloomage Biotechnology Corp....

Manufacturer Address : No 678, Tianchen St., High-Tech Development Zone, Jinan, Shandong province, China

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Sodium hyaluronate

Registrant Name : IMCD Korea Co., Ltd.

Registration Date : 2017-12-08

Registration Number : 20151016-96-E-123-38(6)

Manufacturer Name : Bloomage Biotechnology Corp....

Manufacturer Address : No. 678 Tianchen St., High-Tech Development Zone, Jian City, Shandong Province, PR of...

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Sodium hyaluronate

Registrant Name : Unimed Pharmaceutical Co., Ltd.

Registration Date : 2022-03-23

Registration Number : 20130322-96-E-109-34(A)

Manufacturer Name : Bloomage Biotechnology Corp....

Manufacturer Address : No. 678 Tianchen St., High-Tech Development Zone, Jian City, Shandong Province, PR of...

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Sodium hyaluronate

Registrant Name : Hiple Co., Ltd.

Registration Date : 2022-07-08

Registration Number : 20130322-96-E-109-34(C)

Manufacturer Name : Bloomage Biotechnology Corp....

Manufacturer Address : No 678, Tianchen St., High-Tech Development Zone, Jinan City, Shandong Province, Chin...

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Sodium hyaluronate

Registrant Name : Hiple Co., Ltd.

Registration Date : 2022-07-08

Registration Number : 20211021-96-E-171-54(A)

Manufacturer Name : Bloomage Biotechnology Corp....

Manufacturer Address : No. 678 Tianchen Street, High-Tech Development Zone, Jinan, China.

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Virtual BoothBloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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Sodium hyaluronate

Registrant Name : Seongi Bio Co., Ltd.

Registration Date : 2019-03-06

Registration Number : 20190306-96-E-150-45

Manufacturer Name : Bloomage Biotechnology Corp....

Manufacturer Address : No.678, Tianchen St., High-Tech Development Zone, Jinan, City, Shondong Province, PRo...

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Virtual BoothBloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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Sodium hyaluronate

Registrant Name : Holy Land Ivy Farm

Registration Date : 2017-09-07

Registration Number : 20151016-96-E-123-38(5)

Manufacturer Name : Bloomage Freda Biopharm Co.,...

Manufacturer Address : No.678 Tianchen St., High-Tech Development Zone, Jinan City, Shangdong Province, Chin...

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Virtual BoothBloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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Sodium hyaluronate

Registrant Name : Korea BMI Co., Ltd.

Registration Date : 2017-09-01

Registration Number : 20130412-96-E-108-34(4)

Manufacturer Name : Bloomage Biotechnology Corp....

Manufacturer Address : No 678, Tianchen St., High-Tech Development Zone, Jinan City, Shandong Province, PR o...

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Virtual BoothBloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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Sodium hyaluronate

Registrant Name : MFC Corporation

Registration Date : 2021-10-21

Registration Number : 20211021-96-E-171-54

Manufacturer Name : Bloomage Biotechnology Corp....

Manufacturer Address : No. 678 Tianchen Street, High-Tech Development Zone, Jinan, China.

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Listed Suppliers

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Virtual BoothBloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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Sodium Hyaluronate

About the Company : Bloomage Biotechnology Corporation Limited, formerly Bloomage Freda Biopharm, was established by Bloomage International Investment Group. It is a global leader in bioactive materia...

Bloomage Biotechnology Corporation Limited, formerly Bloomage Freda Biopharm, was established by Bloomage International Investment Group. It is a global leader in bioactive materials like mucopolysaccharides, proteins, peptides, amino acids, & natural compounds. In the 1990s, it became the first company in China to develop fermentation-based sodium hyaluronate. With around 200 specifications of hyaluronic acid, it caters to the pharmaceutical, medical devices, cosmetics, & functional food sectors. For pharma raw materials, Bloomage offers innovative solutions in aesthetics, dermatology, ophthalmology, orthopedics, & regenerative medicines.
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Virtual BoothKewpie is your partner for Sodium Hyaluronate & Hyaluronic Acid// CEP, USDMF, KDMF & JDMF registered.

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Sodium Hyaluronate

About the Company : Kewpie first developed Sodium hyaluronate in 1983 and is currently the leading Japanese manufacturer of pharmaceutical grade Sodium hyaluronate used as an API and pharmaceutical ex...

Kewpie first developed Sodium hyaluronate in 1983 and is currently the leading Japanese manufacturer of pharmaceutical grade Sodium hyaluronate used as an API and pharmaceutical excipients. Its Sodium hyaluronate is suitable for injections, eye drops and external preparations. Its pharmaceutical grade Sodium hyaluronate (Hyaluronic acid) is manufactured at its factory near Tokyo under strict regulations. Since 2016, Kewpie has developed and manufactured medical devices using Sodium hyaluronate. Its R&D team can also provide Sodium hyaluronate derivatives as per clients’ needs. Kewpie exports Sodium hyaluronate to over 30 countries.
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Virtual BoothHTL Biotechnology is a French biotech & a global leader in the responsible development & production of pharma-grade biopolymers.

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Sodium Hyaluronate

About the Company : HTL is a biotechnology company pioneering the development and production of pharmaceutical-grade Hyaluronic Acid (Sodium Hyaluronate) and other functional biopolymers such as PDRN ...

HTL is a biotechnology company pioneering the development and production of pharmaceutical-grade Hyaluronic Acid (Sodium Hyaluronate) and other functional biopolymers such as PDRN and PN, designed to improve people's lives. HTL is the only Hyaluronic Acid producer exclusively producing injectable grade. Our premium quality biopolymers are used by healthcare companies for the development of treatments in various cutting-edge therapeutic areas such as ophthalmology, dermatology, medical aesthetics and rheumatology.
HTL Biotechnology Biopolymer

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Virtual BoothTopscience Biotech specializes in R&D, production, and sales of Sodium Hyaluronate, focusing on Medical and Pharmaceutical Grade HA.

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Sodium Hyaluronate

About the Company : Established in 2005, Topscience located in Lanshan, Rizhao of PRC and covers an area of 100,000m². Products include Sodium Hyaluronate, Chondroitin Sulfate, Alpha-Arbutin, L-Ascor...

Established in 2005, Topscience located in Lanshan, Rizhao of PRC and covers an area of 100,000m². Products include Sodium Hyaluronate, Chondroitin Sulfate, Alpha-Arbutin, L-Ascorbic Acid 2-Glucoside, Sulglycotide etc. We have GMP certificate, Drug manufacturing Certificate, CEP of Sodium Hyaluronate, Written Confirmation, Certificate of DMF Registration, Halal, Kosher etc. Sodium Hyaluronate API includes Injection grade, Eye-Drop grade and Excipients grade. The bacterial endotoxin of Sodium Hyaluronate(Injection Grade) is less than 0.001 IU/mg, which is much lower than European Pharmacopoeia current edition 50 times.
Shandong Topscience Biotech

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Virtual BoothPharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

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Sodium Hyaluronate

About the Company : Pharm-Rx has earned an outstanding reputation since its establishment in 1991, serving as a reputable importer and distributor of active ingredients to the pharmaceutical, nutritio...

Pharm-Rx has earned an outstanding reputation since its establishment in 1991, serving as a reputable importer and distributor of active ingredients to the pharmaceutical, nutritional supplement, and food industries. The company maintains an exceptionally selective approach to its suppliers, personally visiting manufacturers overseas to ensure the highest standards. The sustained growth of Pharm-Rx can be attributed to its steadfast commitment to three core values: quality ingredients, competitive pricing, and unparalleled customer service.
Pharm RX

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Virtual BoothBasic Nutrition, your expert for sourcing from China, India and Europe.

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Sodium Hyaluronate

About the Company : As an ISO9001, ISO22000 certificated supplier, Basic Nutrition supply high-quality ingredients for nutraceuticals. We can offer a range of products from small to large quantites: h...

As an ISO9001, ISO22000 certificated supplier, Basic Nutrition supply high-quality ingredients for nutraceuticals. We can offer a range of products from small to large quantites: herbal extract, amino acid, vitamin, etc. Featured products: cranberry extract, rhidiola extract, Q10, hyaluronic acid, cysteine (non-animals), glutathoninr, orgaic products like organic spirulina, organic red yeast rice powder, etc.
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Sodium Hyaluronate

About the Company : Bio-Technology General (Israel) Ltd. (BTG) is Israel’s leading fully integrated biopharmaceutical services company. A wholly-owned subsidiary of Ferring Pharmaceuticals, BTG is a...

Bio-Technology General (Israel) Ltd. (BTG) is Israel’s leading fully integrated biopharmaceutical services company. A wholly-owned subsidiary of Ferring Pharmaceuticals, BTG is a pioneer in the development and manufacture of human health care products derived from genetic engineering and biotechnology processes.
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Sodium Hyaluronate

About the Company : HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketi...

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, Thinkchem specializes in exporting pharmaceuticals, veterinary drugs, feed additives, intermediates, fine chemicals, plants extracts, pesticides, food & nutrition additives. Thinkchem is good at offering excellent outsourcing services to overseas customers as well as laboratory support. Thinkchem is equipped with modern lab apparatus including HPLC, GC. TLC AND NMR, motivated by a team of highly qualified personnel using these equipments.
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Sodium Hyaluronate

About the Company : Vital Group of companies is a leading Manufacturer and Exporter of Active Pharmaceutical Ingredients (API). Founded in 1999 Vital set up a unit for manufacturing for Quinine Salts ...

Vital Group of companies is a leading Manufacturer and Exporter of Active Pharmaceutical Ingredients (API). Founded in 1999 Vital set up a unit for manufacturing for Quinine Salts and Alkaloids and within short span of time since inception Vital has taken giant strides in its continuous journey of growth by expanding its plant to a land area of 25000 sq.meters. Vital also expanded its product line of Anti Malarias from “QUININE SALTS” to “ARTEMESININ” derivatives and other Anti Malarial API’S. Besides anti Malaria Vital has further ventured into other theuropatic segments.
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SODIUM HYALURONATE POWDER,

About the Company : With over a decade of experience in the Pharmaceutical and Health sector, HNB stands as a contemporary company specializing in the exploration, advancement, manufacturing, processi...

With over a decade of experience in the Pharmaceutical and Health sector, HNB stands as a contemporary company specializing in the exploration, advancement, manufacturing, processing, and global exportation of Active Pharmaceutical Ingredients (API), diverse additives encompassing those for food, feed, and cosmetics, a range of hormone products, and other related items since the year 2007.We pride ourselves on being your premier supplier, offering a wider array and the utmost quality in products. Our primary offerings include API, assorted additive products, and select Polypeptide Hormones.
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API Reference Price

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UNITED KINGDOM , , UNITED KINGDOM UNITED KINGDOM","customerAddress":"GROUND FLOOR, CORPORATE ONE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715884200,"product":"10326 SODIUM HYALURONATE LMW (10,000 - 20,000 DA)(RAW MATERIAL FOR COSMETICS USE)","address":"GROUND FLOOR, CORPORATE ONE","city":"DELHI","supplier":"AMMEREX LTD","supplierCountry":"UNITED KINGDOM","foreign_port":"LONDON - HEATHROW","customer":"ORIFLAME INDIA PRIVATE ","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"667.4","totalValueFC":"1615.9","currency":"EUR","unitRateINR":"67346.3","date":"17-May-2024","totalValueINR":"134692.51","totalValueInUsd":"1615.9","indian_port":"Delhi Air","hs_no":"29163940","bill_no":"3533561","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED KINGDOM","selfForZScoreResived":"Pharma Grade","supplierPort":"LONDON - HEATHROW","supplierAddress":"UNIT 2 CORINIUM IND ESTATE RAANS ROAD, AMERSHAM HP5 6JQ. UNITED KINGDOM , , UNITED KINGDOM UNITED KINGDOM","customerAddress":"GROUND FLOOR, CORPORATE ONE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718217000,"product":"SODIUM HYALURONATE EP","address":"UNIT NO 17 GR FL ANDHERI INDL","city":"ROAD, ANDHERI(W), MUMBAI ,","supplier":"BLOOMAGE BIOTECHNOLOGY CORP., LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"RENAISSANCE PHARMA","customerCountry":"INDIA","quantity":"40.00","actualQuantity":"40","unit":"KGS","unitRateFc":"800","totalValueFC":"32330.7","currency":"USD","unitRateINR":"67473.7","date":"13-Jun-2024","totalValueINR":"2698948.8","totalValueInUsd":"32330.7","indian_port":"Bangalore Air","hs_no":"29309099","bill_no":"3965709","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"LTD.,NO. 678, TIANCHEN ST., HIGH - TECHDEVELOPMENT ZONE, JINAN CHINA","customerAddress":"UNIT NO 17 GR FL ANDHERI INDL"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720031400,"product":"SODIUM HYALURONATE EP","address":"SHIV KRUPA HOUSE NO 499 R NO. 5 1ST FLOOR","city":"MUMBAI","supplier":"BIOPHARM","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"JINESHWAR ENTERPRISE","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"8500","totalValueFC":"4572.6","currency":"USD","unitRateINR":"764453.5","date":"04-Jul-2024","totalValueINR":"382226.74","totalValueInUsd":"4572.6","indian_port":"Bangalore Air","hs_no":"29309099","bill_no":"4317152","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"NO488 HUANGHE 12TH ROAD BINZHOUSHANDONGSDNF CHINA","customerAddress":"SHIV KRUPA HOUSE NO 499 R NO. 5 1ST FLOOR"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723487400,"product":"SODIUM HYALURONATE","address":"408,409 SHAIL COMPLEX,OP-MADHUSUDAN","city":"EXCHANGE,ELLISBRIDGE,AHMEDABAD","supplier":"SHANDONG FOCUSFREDA BIOTECH CO., LT","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"METEORIC BIOPHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"200","totalValueFC":"100.9","currency":"USD","unitRateINR":"16920","date":"13-Aug-2024","totalValueINR":"8460","totalValueInUsd":"100.9","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"5041037","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"D NEW ECONOMIC DEVELOPMENT ZONE OFHIGH SPEED RAIL,QUFU, JINING,SHANDONG, CHINA","customerAddress":"408,409 SHAIL COMPLEX,OP-MADHUSUDAN"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727634600,"product":"SODIUM HYALURONATE EP","address":"110-B,ANDHERI INDUSTRIAL ESTATE","city":"ANDHERI(W),MUMBAI, MAHARASHTRA","supplier":"AMHWA BIOPHARM CO. LTD.","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"ADD BIOTEC","customerCountry":"INDIA","quantity":"10.50","actualQuantity":"10.5","unit":"KGS","unitRateFc":"8458","totalValueFC":"89756.1","currency":"USD","unitRateINR":"716349.5","date":"30-Sep-2024","totalValueINR":"7521669.4","totalValueInUsd":"89756.1","indian_port":"Bombay Air","hs_no":"29309099","bill_no":"5878780","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"NO. 488 HUANGHE 12TH ROAD BINZHOU, SHANDONG CHINA Shandong, Shandong, CHINA CHINA","customerAddress":"110-B,ANDHERI INDUSTRIAL ESTATE"}]
07-Jan-2021
30-Sep-2024
KGS
overview
Loading...

Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

Upgrade, download data, analyse, strategize, subscribe with us contact

Europe

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01

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

Sulfadiazine Silver; Sodium Hyaluronate

Brand Name : Connettivina Plus

Dosage Form :

Dosage Strength : Cream Derm 25 G  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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02

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

Sulfadiazine Silver; Sodium Hyaluronate

Brand Name : Connettivina Plus

Dosage Form :

Dosage Strength : 10 Gauzes 10 Cm X 10 Cm 2 Mg + 40 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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03

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

Sulfadiazine Silver; Sodium Hyaluronate

Brand Name : Connettivina Plus

Dosage Form :

Dosage Strength : 10 Gauzes 10 Cm X 20 Cm 4 Mg + 80 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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04

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

Sulfadiazine Silver; Sodium Hyaluronate

Brand Name : Connettivina Plus

Dosage Form :

Dosage Strength : 5 Gauze 20 Cm X 30 Cm 12 Mg + 240 Mg  

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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05

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

Sodium hyaluronate; Sulfadiazinum argenticum

Brand Name : Ialugen Plus Cream

Dosage Form : Cream

Dosage Strength :

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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06

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

Sodium hyaluronate; Sulfadiazinum argenticum

Brand Name : Ialugen Plus Cream

Dosage Form : Cream

Dosage Strength :

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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07

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

Sodium Hyaluronate

Brand Name :

Dosage Form :

Dosage Strength : 20MG/2ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Turkey

blank

08

OmniVision AG

Switzerland
AES 2024
Not Confirmed
arrow

OmniVision AG

Switzerland
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AES 2024
Not Confirmed

Natrii hyaluronas

Brand Name : Lacri-Vision

Dosage Form : Eye Gel

Dosage Strength :

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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09

OmniVision AG

Switzerland
AES 2024
Not Confirmed
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OmniVision AG

Switzerland
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AES 2024
Not Confirmed

Natrii hyaluronas

Brand Name : Lacri-Vision

Dosage Form : Eye Gel

Dosage Strength :

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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10

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

natriumhyaluronat

Brand Name : Hyalgan

Dosage Form : INJEKTIONSVÄTSKA, LÖSNING

Dosage Strength : 10 MG/ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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Canada

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01

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

HYALURONATE SODIUM

Brand Name : LEGEND

Dosage Form : SOLUTION

Dosage Strength : 10MG/ML

Packaging : 2ML/4ML

Approval Date :

Application Number : 2169541

Regulatory Info : Prescription

Registration Country : Canada

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02

DECHRA LTD

United Kingdom
AES 2024
Not Confirmed
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DECHRA LTD

United Kingdom
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AES 2024
Not Confirmed

HYALURONATE SODIUM

Brand Name : HY-50

Dosage Form : SOLUTION

Dosage Strength : 17MG/ML

Packaging : 3ML

Approval Date :

Application Number : 2238566

Regulatory Info : Prescription

Registration Country : Canada

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03

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

HYALURONATE SODIUM

Brand Name : NEXHA

Dosage Form : SOLUTION

Dosage Strength : 10MG/ML

Packaging : 2ML-IA/4ML-IV

Approval Date :

Application Number : 2375176

Regulatory Info : Prescription

Registration Country : Canada

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Australia

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01

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

hyaluronate sodium

Brand Name : Hylo-Forte

Dosage Form :

Dosage Strength :

Packaging : 1

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

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02

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

hyaluronate sodium

Brand Name : Hylo-Fresh

Dosage Form :

Dosage Strength :

Packaging : 1

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

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03

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

hyaluronate sodium

Brand Name : Hylo-Fresh

Dosage Form :

Dosage Strength :

Packaging : 1

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

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04

AES 2024
Not Confirmed
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AES 2024
Not Confirmed

hyaluronate sodium

Brand Name : Hylo-Forte

Dosage Form :

Dosage Strength :

Packaging : 1

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

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Listed Dossiers

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01

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Brand Name : Hylaform 0,1%

Dosage Form : Ophthalmic Solution

Dosage Strength : 1MG/ML

Packaging : Unit & Multi Dose Ophthalmic

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Vietnam

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01

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Dosage : Ophthalmic Solution

Dosage Strength : 1MG/ML

Brand Name : Hylaform 0,1%

Approval Date :

Application Number :

Registration Country : Vietnam

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02

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Brand Name : Afenemi

Dosage Form : Ophthalmic Solution

Dosage Strength : 1.8MG/ML

Packaging : Unit & Multi Dose Ophthalmic

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Vietnam

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02

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Dosage : Ophthalmic Solution

Dosage Strength : 1.8MG/ML

Brand Name : Afenemi

Approval Date :

Application Number :

Registration Country : Vietnam

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03

Hanlim Pharmaceutical

South Korea
Antibody Engineering
Not Confirmed
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Hanlim Pharmaceutical

South Korea
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Brand Name : HYALURON

Dosage Form : EYE DROP

Dosage Strength : 1MG/ML

Packaging : 5mL & 0.6mL*30ea

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Korea

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03

Hanlim Pharmaceutical

South Korea
Antibody Engineering
Not Confirmed
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Hanlim Pharmaceutical

South Korea
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Dosage : EYE DROP

Dosage Strength : 1MG/ML

Brand Name : HYALURON

Approval Date :

Application Number :

Registration Country : South Korea

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04

IBN Savio

Italy
Antibody Engineering
Not Confirmed
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IBN Savio

Italy
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Brand Name :

Dosage Form : Prefilled Syringe

Dosage Strength : 3UNIT

Packaging : 2 ml prefilled syringe

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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04

IBN Savio

Italy
Antibody Engineering
Not Confirmed
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IBN Savio

Italy
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Dosage : Prefilled Syringe

Dosage Strength : 3UNIT

Brand Name :

Approval Date :

Application Number :

Registration Country : Italy

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05

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

D-Panthenol; Aloe vera; Sodium Hyaluronate

Brand Name :

Dosage Form : Lotion

Dosage Strength :

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Germany

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05

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

D-Panthenol; Aloe vera; Sodium Hyaluronate

Dosage : Lotion

Dosage Strength :

Brand Name :

Approval Date :

Application Number :

Registration Country : Germany

blank

06

Teknomek

Turkey
Antibody Engineering
Not Confirmed
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Teknomek

Turkey
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Brand Name : Hyotek

Dosage Form : Ophthalmic Solution

Dosage Strength : 3%

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Turkey

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06

Teknomek

Turkey
Antibody Engineering
Not Confirmed
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Teknomek

Turkey
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Dosage : Ophthalmic Solution

Dosage Strength : 3%

Brand Name : Hyotek

Approval Date :

Application Number :

Registration Country : Turkey

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07

Unimed Pharm Inc.

South Korea
Antibody Engineering
Not Confirmed
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Unimed Pharm Inc.

South Korea
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Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Brand Name : Unilon Dispo

Dosage Form : INJECTION

Dosage Strength : 25MG/2.5ML

Packaging : Pre-Filled Syringe (PFS)

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Korea

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07

Unimed Pharm Inc.

South Korea
Antibody Engineering
Not Confirmed
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Unimed Pharm Inc.

South Korea
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Dosage : INJECTION

Dosage Strength : 25MG/2.5ML

Brand Name : Unilon Dispo

Approval Date :

Application Number :

Registration Country : South Korea

blank

08

Unimed Pharm Inc.

South Korea
Antibody Engineering
Not Confirmed
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Unimed Pharm Inc.

South Korea
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Brand Name : Hyalon Dispo

Dosage Form : INJECTION

Dosage Strength : 20MG/2ML

Packaging : Pre-Filled Syringe (PFS)

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Korea

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08

Unimed Pharm Inc.

South Korea
Antibody Engineering
Not Confirmed
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Unimed Pharm Inc.

South Korea
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Dosage : INJECTION

Dosage Strength : 20MG/2ML

Brand Name : Hyalon Dispo

Approval Date :

Application Number :

Registration Country : South Korea

blank

09

Unimed Pharm Inc.

South Korea
Antibody Engineering
Not Confirmed
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Unimed Pharm Inc.

South Korea
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Brand Name : Endo Ease

Dosage Form : INJECTION

Dosage Strength : 10ML

Packaging : Vials

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Korea

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09

Unimed Pharm Inc.

South Korea
Antibody Engineering
Not Confirmed
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Unimed Pharm Inc.

South Korea
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Dosage : INJECTION

Dosage Strength : 10ML

Brand Name : Endo Ease

Approval Date :

Application Number :

Registration Country : South Korea

blank

10

Unimed Pharm Inc.

South Korea
Antibody Engineering
Not Confirmed
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Unimed Pharm Inc.

South Korea
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Brand Name : Endo Ease

Dosage Form : INJECTION

Dosage Strength : 20ML

Packaging : Vials

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Korea

blank

10

Unimed Pharm Inc.

South Korea
Antibody Engineering
Not Confirmed
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Unimed Pharm Inc.

South Korea
arrow
Antibody Engineering
Not Confirmed

Sodium Hyaluronate

Dosage : INJECTION

Dosage Strength : 20ML

Brand Name : Endo Ease

Approval Date :

Application Number :

Registration Country : South Korea

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Parenteral

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Topical

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01

arrow
AES 2024
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothNanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Grade : Parenteral, Oral, Topical

Category : Parenteral, Solubilizers, Topical

02

arrow
AES 2024
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothNanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Grade : Oral, Topical

Category : Solubilizers, Topical

03

arrow
AES 2024
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothNanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Solubilizers

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Granulation

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Co-Processed Excipients

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Emulsifying Agents

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Controlled & Modified Release

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Direct Compression

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Coating Systems & Additives

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Fillers, Diluents & Binders

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothRochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

Grade : Oral

Category : Fillers, Diluents & Binders, Taste Masking

Taste Masking

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothRochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

Grade : Oral

Category : Fillers, Diluents & Binders, Taste Masking

API Stability Enhancers

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Film Formers & Plasticizers

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Surfactant & Foaming Agents

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Disintegrants & Superdisintegrants

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Digital Content read-more

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NEWS #PharmaBuzz

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Global Sales Information

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Finished Drug Prices

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01

Brand Name : Connettivina Plus

Italy
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AES 2024
Not Confirmed

Brand Name : Connettivina Plus

Italy
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AES 2024
Not Confirmed

Silver Sulfadiazine; Sodium Hyaluronate

Dosage Form :

Dosage Strength : Cream Derm 25 G  

Price Per Pack (Euro) : 9.65

Published in :

Country : Italy

RX/OTC/DISCN : Class C

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02

Brand Name : Connettivina Plus

Italy
arrow
AES 2024
Not Confirmed

Brand Name : Connettivina Plus

Italy
arrow
AES 2024
Not Confirmed

Silver Sulfadiazine; Sodium Hyaluronate

Dosage Form :

Dosage Strength : 10 Gauzes 10 Cm X 10 Cm 2 Mg + 40 Mg  

Price Per Pack (Euro) : 10.7

Published in :

Country : Italy

RX/OTC/DISCN : Class C

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03

Brand Name : Connettivina Plus

Italy
arrow
AES 2024
Not Confirmed

Brand Name : Connettivina Plus

Italy
arrow
AES 2024
Not Confirmed

Silver Sulfadiazine; Sodium Hyaluronate

Dosage Form :

Dosage Strength : 10 Gauzes 10 Cm X 20 Cm 4 Mg + 80 Mg  

Price Per Pack (Euro) : 14.2

Published in :

Country : Italy

RX/OTC/DISCN : Class C

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04

Brand Name : Connettivina Plus

Italy
arrow
AES 2024
Not Confirmed

Brand Name : Connettivina Plus

Italy
arrow
AES 2024
Not Confirmed

Silver Sulfadiazine; Sodium Hyaluronate

Dosage Form :

Dosage Strength : 5 Gauze 20 Cm X 30 Cm 12 Mg + 240 Mg  

Price Per Pack (Euro) : 17.38

Published in :

Country : Italy

RX/OTC/DISCN : Class C

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05

Brand Name : Ialugen Plus Cream

Switzerland
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AES 2024
Not Confirmed

Brand Name : Ialugen Plus Cream

Switzerland
arrow
AES 2024
Not Confirmed

Sodium Hyaluronate; Sulfadiazine

Dosage Form : Cream

Dosage Strength :

Price Per Pack (Euro) : 6.55

Published in :

Country : Switzerland

RX/OTC/DISCN : Class B

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06

Brand Name : Ialugen Plus Cream

Switzerland
arrow
AES 2024
Not Confirmed

Brand Name : Ialugen Plus Cream

Switzerland
arrow
AES 2024
Not Confirmed

Sodium Hyaluronate; Sulfadiazine

Dosage Form : Cream

Dosage Strength :

Price Per Pack (Euro) : 12.9

Published in :

Country : Switzerland

RX/OTC/DISCN : Class B

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07

Brand Name : Ialugen Plus Cream

Switzerland
arrow
AES 2024
Not Confirmed

Brand Name : Ialugen Plus Cream

Switzerland
arrow
AES 2024
Not Confirmed

Sodium Hyaluronate; Sulfadiazine

Dosage Form : Cream

Dosage Strength :

Price Per Pack (Euro) : 76.3

Published in :

Country : Switzerland

RX/OTC/DISCN : Class B

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08

Brand Name : Ialugen Creme

Switzerland
arrow
AES 2024
Not Confirmed

Brand Name : Ialugen Creme

Switzerland
arrow
AES 2024
Not Confirmed

Sodium Hyaluronate

Dosage Form : Creme

Dosage Strength :

Price Per Pack (Euro) : 10.98

Published in :

Country : Switzerland

RX/OTC/DISCN : Class D

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09

Brand Name : Ialugen Creme

Switzerland
arrow
AES 2024
Not Confirmed

Brand Name : Ialugen Creme

Switzerland
arrow
AES 2024
Not Confirmed

Sodium Hyaluronate

Dosage Form : Creme

Dosage Strength :

Price Per Pack (Euro) : 21.9

Published in :

Country : Switzerland

RX/OTC/DISCN : Class D

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10

Brand Name : Altergen

Country
arrow
AES 2024
Not Confirmed

Brand Name : Altergen

Country
arrow
AES 2024
Not Confirmed

Silver Sulfadiazine; Sodium Hyaluronate

Dosage Form :

Dosage Strength : Cream Derm 25 G  

Price Per Pack (Euro) : 9.3

Published in :

Country : Italy

RX/OTC/DISCN : Class C

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Market Place

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APIs

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FDF DOSSIERS

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04 Jul 2016

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04 Jul 2016

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04 Jul 2016

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REF. STANDARDS & IMPURITIES

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EDQM

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01

EDQM, Council of Europe

Sodium hyaluronate - reference spectrum

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Antibody Engineering
Not Confirmed
Antibody Engineering
Not Confirmed

Sodium hyaluronate - reference spectrum

CAS Number : n/a

Quantity Per Vial : n/a

Sale Unit : 1

Order Code : S0781000

Batch No : 1

Price (€) : 79

Storage :

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USP

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01

USP

U.S.A
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AES 2024
Not Confirmed

Others

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01

USP

U.S.A
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Antibody Engineering
Not Confirmed

USP

U.S.A
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Antibody Engineering
Not Confirmed

Sodium Hyaluronate for IR Identification (250...

CAS Number : 9067-32-7

Quantity Per Vial : 250

Sale Unit : mg

Price : $235.00

Details : Material Origin- Fermentation; USMCA- No; KOR...

Monograph :

Storage :

Code/Batch No : Catalog #1614159 / F0M296

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