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Chemistry

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Also known as: Sodium iodide i-131, Sodium iodide-131, 7790-26-3, Theriodide, Tracervial, Iodotope
Molecular Formula
INa
Molecular Weight
153.895896  g/mol
InChI Key
FVAUCKIRQBBSSJ-LAIFMVDKSA-M
FDA UNII
29VCO8ACHH

Sodium Iodide-131
Sodium Iodide I-131 is a radiopharmaceutical containing the beta- and gamma-emitting radioisotope I-131. After absorption, the iodide is distributed through the extracellular fluid of the body and accumulates in the thyroid gland, thereby allowing the imaging of the thyroid.
1 2D Structure

Sodium Iodide-131

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;iodine-131(1-)
2.1.2 InChI
InChI=1S/HI.Na/h1H;/q;+1/p-1/i1+4;
2.1.3 InChI Key
FVAUCKIRQBBSSJ-LAIFMVDKSA-M
2.1.4 Canonical SMILES
[Na+].[I-]
2.1.5 Isomeric SMILES
[Na+].[131I-]
2.2 Other Identifiers
2.2.1 UNII
29VCO8ACHH
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Sodium Iodide I-131

2. Sodium Iodide-131

3. 7790-26-3

4. Theriodide

5. Tracervial

6. Iodotope

7. Oriodide

8. Radiocaps

9. Sodium Iodide (131i)

10. Sodium Iodide, I-131

11. Sodium;iodine-131(1-)

12. Theriodide-131

13. Tracervial-131

14. Radiocaps-131

15. Sodium Iodide I131

16. Iodine (131i) Sodium

17. 29vco8achh

18. Sodium Iodide (131 I)

19. Sodium Iodide (na131i)

20. Sodium Iodide (131i) [inn]

21. Hicon

22. Natrii Radioiodidum

23. Iodotope (tn)

24. Iodotope Therapeutic

25. Hicon (tn)

26. Iodotope I-131

27. Sodium Iodide-131i

28. Sodium Iodide,i-131

29. Unii-29vco8achh

30. (131-i)sodium Iodide

31. Ioduro Sodico (131i)

32. Natrii Iodidum (131i)

33. Sodium Iodide, Radioactive

34. Ioduro Sodico (131 I)

35. Sodium Iodide (i-131)

36. Natrii Iodidum (131 I)

37. Natrii Jodidum (131 I)

38. Iodure (131i) De Sodium

39. Sodium Iodide I 131, Kit

40. Iodure (131 I) De Sodium

41. Natrium Radio-iodatum (131i)

42. Chembl1201084

43. Natrium Radio-iodatum (131 I)

44. Sodium Iodide (131i) Capsules

45. Sodium Iodide (na(sup 131)i)

46. Dtxsid701014487

47. Sodium Iodide I 131 [mi]

48. Sodium Iodide I 131 (jp17/usp)

49. Sodium Iodide I 131 [hsdb]

50. Sodium Iodide I 131 [usan]

51. Sodium Iodide ((sup 131)i) Capsules

52. Sodium Iodide,i-131 [vandf]

53. Natrii Iodidum (131 I) [inn-latin]

54. Ioduro Sodico (131 I) [inn-spanish]

55. Sodium Iodide I 131 [usan:usp:inn]

56. Iodure (131 I) De Sodium [inn-french]

57. Sodium Iodide (131 I) [who-dd]

58. Sodium Iodide I-131 [orange Book]

59. Sodium Iodide I 131 [usp Impurity]

60. D02259

61. Q22075909

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 153.895896 g/mol
Molecular Formula INa
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass153.895896 g/mol
Monoisotopic Mass153.895896 g/mol
Topological Polar Surface Area0 Ų
Heavy Atom Count2
Formal Charge0
Complexity2
Isotope Atom Count1
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NameSodium iodide i 131
Active IngredientSodium iodide i-131
Dosage FormCapsule; Solution
RouteOral
Strength3.5-150mci/vial; 0.8-100mci
Market StatusPrescription
CompanyMallinckrodt

2 of 4  
Drug NameSodium iodide i-131
Active IngredientSodium iodide i-131
Dosage FormCapsule
RouteOral
Strength9-100mci
Market StatusPrescription
CompanyJubilant Draximage

3 of 4  
Drug NameSodium iodide i 131
Active IngredientSodium iodide i-131
Dosage FormCapsule; Solution
RouteOral
Strength3.5-150mci/vial; 0.8-100mci
Market StatusPrescription
CompanyMallinckrodt

4 of 4  
Drug NameSodium iodide i-131
Active IngredientSodium iodide i-131
Dosage FormCapsule
RouteOral
Strength9-100mci
Market StatusPrescription
CompanyJubilant Draximage

5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Pharmacological Classes
Radiopharmaceutical Activity [MoA]; Radioactive Therapeutic Agent [EPC]
5.2 ATC Code

V - Various

V09 - Diagnostic radiopharmaceuticals

V09F - Thyroid

V09FX - Various thyroid diagnostic radiopharmaceuticals

V09FX03 - Sodium iodide (131I)


V - Various

V10 - Therapeutic radiopharmaceuticals

V10X - Other therapeutic radiopharmaceuticals

V10XA - Iodine (131i) compounds

V10XA01 - Sodium iodide (131I)


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DOSAGE - SOLUTION;ORAL - 3.5-150mCi/VIAL

USFDA APPLICATION NUMBER - 16515

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DOSAGE - CAPSULE;ORAL - 0.8-100mCi

USFDA APPLICATION NUMBER - 16517

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DOSAGE - CAPSULE;ORAL - 0.009-0.1mCi

USFDA APPLICATION NUMBER - 21305

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DOSAGE - SOLUTION;ORAL - 250-1000mCi

USFDA APPLICATION NUMBER - 21305

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