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Chemistry

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Also known as: Sodium ioxaglate, 67992-58-9, Ioxaglate sodium [usan], Hq43cn02u9, Hexabrix, Ioxaglate sodium (usan)
Molecular Formula
C24H20I6N5NaO8
Molecular Weight
1290.9  g/mol
InChI Key
MBVDCEVFLAONHO-UHFFFAOYSA-M
FDA UNII
HQ43CN02U9

Sodium Ioxaglate
A low-osmolar, ionic contrast medium used in various radiographic procedures.
1 2D Structure

Sodium Ioxaglate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;3-[[2-[[3-[acetyl(methyl)amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoyl]amino]acetyl]amino]-5-(2-hydroxyethylcarbamoyl)-2,4,6-triiodobenzoate
2.1.2 InChI
InChI=1S/C24H21I6N5O8.Na/c1-7(37)35(3)20-17(29)10(21(39)31-2)13(25)11(18(20)30)23(41)33-6-8(38)34-19-15(27)9(22(40)32-4-5-36)14(26)12(16(19)28)24(42)43;/h36H,4-6H2,1-3H3,(H,31,39)(H,32,40)(H,33,41)(H,34,38)(H,42,43);/q;+1/p-1
2.1.3 InChI Key
MBVDCEVFLAONHO-UHFFFAOYSA-M
2.1.4 Canonical SMILES
CC(=O)N(C)C1=C(C(=C(C(=C1I)C(=O)NCC(=O)NC2=C(C(=C(C(=C2I)C(=O)[O-])I)C(=O)NCCO)I)I)C(=O)NC)I.[Na+]
2.2 Other Identifiers
2.2.1 UNII
HQ43CN02U9
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Hexabrix

2. Ioxaglate

3. Ioxaglate Meglumine

4. Ioxaglate, Methylglucamine

5. Ioxaglic Acid

6. Ioxaglic Acid Monosodium Salt

7. Ioxaglic Acid, Calcium Salt (2:1)

8. Meglumine, Ioxaglate

9. Methylglucamine Ioxaglate

10. P-286 (contrast Media)

11. P286 (contrast Media)

2.3.2 Depositor-Supplied Synonyms

1. Sodium Ioxaglate

2. 67992-58-9

3. Ioxaglate Sodium [usan]

4. Hq43cn02u9

5. Hexabrix

6. Ioxaglate Sodium (usan)

7. Sodium N-(2-hydroxyethyl)-2,4,6-triiodo-5-(2-(2,4,6-triiodo-3-(n-methylacetamido)-5-(methylcarbamoyl)benzamido)acetamido)isophthalamate

8. Sodium;3-[[2-[[3-[acetyl(methyl)amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoyl]amino]acetyl]amino]-5-(2-hydroxyethylcarbamoyl)-2,4,6-triiodobenzoate

9. Benzoic Acid, 3-((((3-(acetylmethylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)benzoyl)amino)acetyl)amino)-5-(((2-hydroxyethyl)amino)carbonyl)-2,4,6-triiodo-, Sodium Salt

10. Unii-hq43cn02u9

11. Einecs 268-060-2

12. Ioxaglic Acid Sodium

13. Schembl492669

14. Chembl1200743

15. Ioxaglate Sodium [vandf]

16. Dtxsid40218187

17. Sodium Ioxaglate [mart.]

18. Ioxaglate Sodium [who-dd]

19. Ioxaglate Sodium [orange Book]

20. Hexabrix Component Ioxaglate Sodium

21. Ft-0670407

22. Ioxaglate Sodium Component Of Hexabrix

23. D04599

24. Q27280055

25. Benzoic Acid, 3-((((3-(acetylmethylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)benzoyl)amino)acetyl)amino)-5-(((2-hydroxyethyl)amino)carbonyl)-2,4,6-triiodo-, Monosodium Salt

26. Sodium 3-((((3-(acetylmethylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)benzoyl)amino)acetyl)amino)-5-(((2-hydroxyethyl)amino)carbonyl)-2,4,6-triiodobenzoate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 1290.9 g/mol
Molecular Formula C24H20I6N5NaO8
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count10
Exact Mass1290.5478 g/mol
Monoisotopic Mass1290.5478 g/mol
Topological Polar Surface Area197 Ų
Heavy Atom Count44
Formal Charge0
Complexity1100
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Contrast Media

Substances used to allow enhanced visualization of tissues. (See all compounds classified as Contrast Media.)


ABOUT THIS PAGE

Sodium Ioxaglate Manufacturers

A Sodium Ioxaglate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sodium Ioxaglate, including repackagers and relabelers. The FDA regulates Sodium Ioxaglate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sodium Ioxaglate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sodium Ioxaglate Suppliers

A Sodium Ioxaglate supplier is an individual or a company that provides Sodium Ioxaglate active pharmaceutical ingredient (API) or Sodium Ioxaglate finished formulations upon request. The Sodium Ioxaglate suppliers may include Sodium Ioxaglate API manufacturers, exporters, distributors and traders.

Sodium Ioxaglate GMP

Sodium Ioxaglate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sodium Ioxaglate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sodium Ioxaglate GMP manufacturer or Sodium Ioxaglate GMP API supplier for your needs.

Sodium Ioxaglate CoA

A Sodium Ioxaglate CoA (Certificate of Analysis) is a formal document that attests to Sodium Ioxaglate's compliance with Sodium Ioxaglate specifications and serves as a tool for batch-level quality control.

Sodium Ioxaglate CoA mostly includes findings from lab analyses of a specific batch. For each Sodium Ioxaglate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sodium Ioxaglate may be tested according to a variety of international standards, such as European Pharmacopoeia (Sodium Ioxaglate EP), Sodium Ioxaglate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sodium Ioxaglate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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