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Chemistry

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Also known as: 1847-58-1, Lathanol, Lathanol lal, Nacconol lal, Acetic acid, sulfo-, 1-dodecyl ester, sodium salt, Sulfoacetic acid dodecyl ester s-sodium salt
Molecular Formula
C14H27NaO5S
Molecular Weight
330.42  g/mol
InChI Key
UAJTZZNRJCKXJN-UHFFFAOYSA-M
FDA UNII
D0Y70F2B9J

Sodium lauryl sulfoacetate
Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products.
1 2D Structure

Sodium lauryl sulfoacetate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;2-dodecoxy-2-oxoethanesulfonate
2.1.2 InChI
InChI=1S/C14H28O5S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-19-14(15)13-20(16,17)18;/h2-13H2,1H3,(H,16,17,18);/q;+1/p-1
2.1.3 InChI Key
UAJTZZNRJCKXJN-UHFFFAOYSA-M
2.1.4 Canonical SMILES
CCCCCCCCCCCCOC(=O)CS(=O)(=O)[O-].[Na+]
2.2 Other Identifiers
2.2.1 UNII
D0Y70F2B9J
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 1847-58-1

2. Lathanol

3. Lathanol Lal

4. Nacconol Lal

5. Acetic Acid, Sulfo-, 1-dodecyl Ester, Sodium Salt

6. Sulfoacetic Acid Dodecyl Ester S-sodium Salt

7. Sodium 2-(dodecyloxy)-2-oxoethane-1-sulphonate

8. Sodium 2-(dodecyloxy)-2-oxoethanesulfonate

9. Acetic Acid, Sulfo-, Dodecyl Ester, S-sodium Salt

10. D0y70f2b9j

11. Herba Houttuyniae

12. Lathanol-lal 70

13. Dodecyl Sodium Sulfoacetate

14. Hsdb 7256

15. Dodecyl Sulfoacetate S-sodium Salt

16. Einecs 217-431-7

17. Unii-d0y70f2b9j

18. Sulfoacetic Acid 1-dodecyl Ester, Sodium Salt

19. Sulfoacetic Acid, 1-dodecyl Ester, Sodium Salt

20. Sodium Houttyfonate

21. Schembl121777

22. Dtxsid4027442

23. Bcp18547

24. Akos015900630

25. Sodium Lauryl Sulfoacetate, Aldrichcpr

26. Sodium;2-dodecoxy-2-oxoethanesulfonate

27. Ccg-267809

28. Db13157

29. Sodium Lauryl Sulfoacetate [ii]

30. Sodium Lauryl Sulfoacetate [hsdb]

31. Sodium Lauryl Sulfoacetate [inci]

32. Sodium Lauryl Sulfoacetate [vandf]

33. Sodium2-(dodecyloxy)-2-oxoethanesulfonate

34. Hy-107789

35. Sodium Lauryl Sulfoacetate [who-dd]

36. Cs-0030663

37. Ft-0657433

38. Na 2-(dodecyloxy)-2-oxoethane-1-sulphonate

39. H11025

40. W-109718

41. Q27275949

42. Acetic Acid, 2-sulfo-, Dodecyl Ester, Sodium Salt (1:1)

43. Sodium New Houttuyfonate Pound>>sodium Houttuyfonate Pound>>lathanol Lal Pound>>nacconol Lal

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 330.42 g/mol
Molecular Formula C14H27NaO5S
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count14
Exact Mass330.14768941 g/mol
Monoisotopic Mass330.14768941 g/mol
Topological Polar Surface Area91.9 Ų
Heavy Atom Count21
Formal Charge0
Complexity338
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Indication

Sodium lauryl sulfoacetate is not an active pharmacological ingredient in pharmaceutical preparations and so has no official indication.


5 Pharmacology and Biochemistry
5.1 Pharmacology

Sodium lauryl sulfoacetate acts as a wetting agent and surfactant in pharmaceutical preparations. It is currently used in enema-type laxatives.


5.2 ATC Code

B05XA02

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355


5.3 Absorption, Distribution and Excretion

Sodium lauryl Sulfoacetate can be absorbed through guinea pig skin. Two groups of 6 female weanling guinea pigs were immersed in either 0.2% aqueous sodium lauryl sulfoacetate or distilled water for 4 hr on 3 consecutive days. ... Seven blood samples were taken before and after each immersion and 24 hr after the final immersion. ....The blood concentrations of sodium lauryl sulfoacetate reached a maximum at the end of each immersion, which increased with each subsequent immersion.

Christian M, ed; J American College of Toxicology 6 (3): 261- 278 (1987)


API Reference Price

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05-Apr-2021
02-Nov-2024
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ABOUT THIS PAGE

Sodium lauryl sulfoacetate Manufacturers

A Sodium lauryl sulfoacetate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sodium lauryl sulfoacetate, including repackagers and relabelers. The FDA regulates Sodium lauryl sulfoacetate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sodium lauryl sulfoacetate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Sodium lauryl sulfoacetate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Sodium lauryl sulfoacetate Suppliers

A Sodium lauryl sulfoacetate supplier is an individual or a company that provides Sodium lauryl sulfoacetate active pharmaceutical ingredient (API) or Sodium lauryl sulfoacetate finished formulations upon request. The Sodium lauryl sulfoacetate suppliers may include Sodium lauryl sulfoacetate API manufacturers, exporters, distributors and traders.

click here to find a list of Sodium lauryl sulfoacetate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sodium lauryl sulfoacetate USDMF

A Sodium lauryl sulfoacetate DMF (Drug Master File) is a document detailing the whole manufacturing process of Sodium lauryl sulfoacetate active pharmaceutical ingredient (API) in detail. Different forms of Sodium lauryl sulfoacetate DMFs exist exist since differing nations have different regulations, such as Sodium lauryl sulfoacetate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Sodium lauryl sulfoacetate DMF submitted to regulatory agencies in the US is known as a USDMF. Sodium lauryl sulfoacetate USDMF includes data on Sodium lauryl sulfoacetate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Sodium lauryl sulfoacetate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Sodium lauryl sulfoacetate suppliers with USDMF on PharmaCompass.

Sodium lauryl sulfoacetate GMP

Sodium lauryl sulfoacetate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sodium lauryl sulfoacetate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sodium lauryl sulfoacetate GMP manufacturer or Sodium lauryl sulfoacetate GMP API supplier for your needs.

Sodium lauryl sulfoacetate CoA

A Sodium lauryl sulfoacetate CoA (Certificate of Analysis) is a formal document that attests to Sodium lauryl sulfoacetate's compliance with Sodium lauryl sulfoacetate specifications and serves as a tool for batch-level quality control.

Sodium lauryl sulfoacetate CoA mostly includes findings from lab analyses of a specific batch. For each Sodium lauryl sulfoacetate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sodium lauryl sulfoacetate may be tested according to a variety of international standards, such as European Pharmacopoeia (Sodium lauryl sulfoacetate EP), Sodium lauryl sulfoacetate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sodium lauryl sulfoacetate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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