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Sodium Metasilicate

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FINISHED DOSAGE FORMULATIONS

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2 Canada

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3 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: Sodium metasilicate, 6834-92-0, Waterglass, Sodium polysilicate, Water glass, Disodium metasilicate

Molecular Formula

Na₂O₃Si

Molecular Weight

122.063 g/mol

InChI Key

NTHWMYGWWRZVTN-UHFFFAOYSA-N

FDA UNII

052612U92L

1 2D Structure

Sodium Metasilicate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

disodium;dioxido(oxo)silane

2.1.2 InChI

InChI=1S/2Na.O3Si/c;;1-4(2)3/q2*+1;-2

2.1.3 InChI Key

NTHWMYGWWRZVTN-UHFFFAOYSA-N

2.1.4 Canonical SMILES

[O-][Si](=O)[O-].[Na+].[Na+]

2.2 Other Identifiers

2.2.1 UNII

052612U92L

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Silicic Acid (h2o3si), Disodium Salt, Pentahydrate

2. Silicic Acid (h2o5si2), Disodium Salt

3. Silicic Acid (h2o7si3), Disodium Salt

4. Silicic Acid (h2o9si4), Disodium Salt

5. Silicic Acid (h4o4si), Tetrasodium Salt

6. Silicic Acid (h7o7si2), Hexasodium Salt

2.3.2 Depositor-Supplied Synonyms

1. Sodium Metasilicate

2. 6834-92-0

3. Waterglass

4. Sodium Polysilicate

5. Water Glass

6. Disodium Metasilicate

7. Sodium Siliconate

8. Sodium Sesquisilicate

9. Sodium Silicate Glass

10. 1344-09-8

11. Sodium Silicate Solution

12. Sodium Water Glass

13. Metso Pentabead 20

14. Metso Beads 2048

15. Sodium Silicate (na2sio3)

16. Silicic Acid (h2sio3), Disodium Salt

17. Sodium Metasilicate, Anhydrous

18. 49fg

19. Disodium Oxosilanediolate

20. Sodium Metasilicate (na2sio3)

21. Mfcd00003492

22. Chebi:60720

23. Britesil

24. Crystamet

25. Orthosil

26. Sikalon

27. Silican

28. Carsil

29. Dryseq

30. Silicic Acid (h2sio3), Disodium Salt, Pentahydrate (8ci,9ci)

31. Soluble Glass

32. 052612u92l

33. Agrosil S

34. Silicic Acid (h2sio3), Sodium Salt (1:2)

35. Agrosil Lr

36. Portil A

37. Silica E

38. Silica K

39. Silica N

40. Silica R

41. Pyramid 1

42. Pyramid 8

43. Simet A

44. Carsil (silicate)

45. Sodium Metasilicate, Puriss.

46. Britesil H 20

47. Britesil H 24

48. Metso Beads, Drymet

49. Disodium Monosilicate

50. Dupont 26

51. Metso 20

52. Metso 99

53. Caswell No. 792

54. As Bond 1001

55. Silicon, Reference Standard Solution

56. L 96 (salt)

57. Hk 30 (van)

58. Hsdb 753

59. Hsdb 5028

60. Einecs 215-687-4

61. Einecs 229-912-9

62. Dp 222

63. Sodium Trisilicate Solution

64. Epa Pesticide Chemical Code 072603

65. Disodium Oxosilanebis(olate)

66. Silicic Acid, Disodium Salt

67. Sodium Metasilicate Anhydrous

68. Unii-ijf18f77l3

69. N 38

70. Q 70

71. Unii-052612u92l

72. Sodium Meta-silicate

73. Sodium Silicon Oxide

74. Silicic Acid (h2sio3) , Disodium Salt

75. Disodium;dioxido(oxo)silane

76. Epitope Id:158534

77. Ec 215-687-4

78. Ec 229-912-9

79. B-w

80. Ijf18f77l3

81. Dtxsid7029669

82. Sodium Metasilicate [mi]

83. Sodium Metasilicate [hsdb]

84. Sodium Metasilicate [inci]

85. Amy37025

86. Sodium Metasilicate [who-dd]

87. Akos024429002

88. S15025

89. Silicic Acid (ch2sio3), Disodium Salt

90. Sodium Silicon Oxide (na2sio3)

91. 84992-49-4

92. P-84

93. Ft-0778173

94. Q425397

95. Sodium Trisilicate, >=18% Na (as Na2o) Basis, >=60% Si (as Sio2) Basis, Powder

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	Na₂O₃Si
Molecular Weight	122.063 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	121.94120896 g/mol
Monoisotopic Mass	121.94120896 g/mol
Topological Polar Surface Area	63.2 Å²
Heavy Atom Count	6
Formal Charge	0
Complexity	18.8
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3

4 Pharmacology and Biochemistry

4.1 Absorption, Distribution and Excretion

Radiolabeled (31)Si-sodium metasilicate, partially neutralized, was given orally to male guinea pigs... Most of the silica was rapidly absorbed and excreted in the urine but a significant amount was retained in the tissues. These findings are consistent with the recognition that silicon is an essential trace element for bone formation in animals.

Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 3067

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ABOUT THIS PAGE

Sodium Metasilicate Manufacturers

A Sodium Metasilicate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sodium Metasilicate, including repackagers and relabelers. The FDA regulates Sodium Metasilicate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sodium Metasilicate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sodium Metasilicate Suppliers

A Sodium Metasilicate supplier is an individual or a company that provides Sodium Metasilicate active pharmaceutical ingredient (API) or Sodium Metasilicate finished formulations upon request. The Sodium Metasilicate suppliers may include Sodium Metasilicate API manufacturers, exporters, distributors and traders.

Sodium Metasilicate GMP

Sodium Metasilicate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sodium Metasilicate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sodium Metasilicate GMP manufacturer or Sodium Metasilicate GMP API supplier for your needs.

Sodium Metasilicate CoA

A Sodium Metasilicate CoA (Certificate of Analysis) is a formal document that attests to Sodium Metasilicate's compliance with Sodium Metasilicate specifications and serves as a tool for batch-level quality control.

Sodium Metasilicate CoA mostly includes findings from lab analyses of a specific batch. For each Sodium Metasilicate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sodium Metasilicate may be tested according to a variety of international standards, such as European Pharmacopoeia (Sodium Metasilicate EP), Sodium Metasilicate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sodium Metasilicate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.