Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

FINISHED DOSAGE FORMULATIONS

1 FDF Dossiers, 1 FDA Orange Book

1 FDF Dossiers
1 FDA Orange Book

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Tolbutamide sodium salt, 473-41-6, Sodium tolbutamide, Orinase diagnostic, Tolbutamide sodium, sterile, Tolbutamide sodium, sterile [usp]

Molecular Formula

C₁₂H₁₇N₂NaO₃S

Molecular Weight

292.33 g/mol

InChI Key

QKHDBRQBSNZFAK-UHFFFAOYSA-M

FDA UNII

E830VC49W5

Tolbutamide Sodium is the sodium salt form of tolbutamide, a short-acting, first-generation sulfonylurea with hypoglycemic activity. Compared to second-generation sulfonylureas, tolbutamide is more likely to cause adverse effects, such as jaundice. This agent is rapidly metabolized by CYPC29.

1 2D Structure

Sodium Orinase

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

sodium;butylcarbamoyl-(4-methylphenyl)sulfonylazanide

2.1.2 InChI

InChI=1S/C12H18N2O3S.Na/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11;/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15);/q;+1/p-1

2.1.3 InChI Key

QKHDBRQBSNZFAK-UHFFFAOYSA-M

2.1.4 Canonical SMILES

CCCCNC(=O)[N-]S(=O)(=O)C1=CC=C(C=C1)C.[Na+]

2.2 Other Identifiers

2.2.1 UNII

E830VC49W5

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. Tolbutamide Sodium Salt

2. 473-41-6

3. Sodium Tolbutamide

4. Orinase Diagnostic

5. Tolbutamide Sodium, Sterile

6. Tolbutamide Sodium, Sterile [usp]

7. E830vc49w5

8. Benzenesulfonamide, N-((butylamino)carbonyl)-4-methyl-, Monosodium Salt

9. Sodium;butylcarbamoyl-(4-methylphenyl)sulfonylazanide

10. Sodium Butamide

11. Sodium Orinase

12. Unii-e830vc49w5

13. 1-butyl-3-(p-tolylsulfonyl)urea Monosodium Salt

14. P-toluenosulfonylbutylomocznik, Sol Sodowa [polish]

15. P-toluenosulfonylbutylomocznik, Sol Sodowa

16. Orinase Diagnostic (tn)

17. Urea, 1-butyl-3-(p-tolylsulfonyl)-, Sodium Salt

18. Chembl1200874

19. Dtxsid50197090

20. Tolbutamide Sodium [vandf]

21. Tolbutamide Sodium [who-dd]

22. Tolbutamide Sodium Salt [mi]

23. Tolbutamide Sodium [orange Book]

24. D06177

25. Q27276989

26. 1-butyl-3-(p-tolylsulfonyl)urea, Monosodium Salt

27. Sodium;n'-butyl-n-(4-methylphenyl)sulfonylcarbamimidate

2.4 Create Date

2008-02-05

3 Chemical and Physical Properties

Molecular Formula	C₁₂H₁₇N₂NaO₃S
Molecular Weight	292.33 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Exact Mass	292.08575786 g/mol
Monoisotopic Mass	292.08575786 g/mol
Topological Polar Surface Area	72.6 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	360
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2