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Chemistry

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Also known as: Sodium pyrophosphate, 7722-88-5, Tspp, Tetrasodium diphosphate, Phosphotex, Diphosphoric acid, tetrasodium salt
Molecular Formula
Na4O7P2
Molecular Weight
265.90  g/mol
InChI Key
FQENQNTWSFEDLI-UHFFFAOYSA-J
FDA UNII
O352864B8Z

Sodium Pyrophosphate
1 2D Structure

Sodium Pyrophosphate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
tetrasodium;phosphonato phosphate
2.1.2 InChI
InChI=1S/4Na.H4O7P2/c;;;;1-8(2,3)7-9(4,5)6/h;;;;(H2,1,2,3)(H2,4,5,6)/q4*+1;/p-4
2.1.3 InChI Key
FQENQNTWSFEDLI-UHFFFAOYSA-J
2.1.4 Canonical SMILES
[O-]P(=O)([O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]
2.2 Other Identifiers
2.2.1 UNII
O352864B8Z
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Anhydrous Sodium Pyrophosphate

2. Disodium Pyrophosphate

3. Sodium Diphosphate

4. Sodium Pyrophosphate

5. Tetrasodium Pyrophosphate, 32p2-labeled Cpd

6. Tetrasodium Pyrophosphate, Decahydrate

7. Trisodium Pyrophosphate

2.3.2 Depositor-Supplied Synonyms

1. Sodium Pyrophosphate

2. 7722-88-5

3. Tspp

4. Tetrasodium Diphosphate

5. Phosphotex

6. Diphosphoric Acid, Tetrasodium Salt

7. Sodium Diphosphate

8. Victor Tspp

9. Caswell No. 847

10. Sodium Pyrophosphate [usan]

11. Sodium Pyrophosphate Tetrabasic

12. Natrium Pyrophosphat

13. Pyrophosphoric Acid Tetrasodium Salt

14. Sodium Diphosphate, Anhydrous

15. Natrium Pyrophosphat [german]

16. Sodium Phosphate (na4p2o7)

17. Hsdb 854

18. Mfcd00003513

19. Na4p2o7

20. Chebi:71240

21. O352864b8z

22. Sodium Pyrophosphate (usan)

23. Sodium Pyrophosphate, Tetrabasic

24. Tetranatriumpyrophosphat [german]

25. Einecs 231-767-1

26. Nsc 56751

27. Epa Pesticide Chemical Code 076405

28. Sodium Diphosphate Tetrabasic

29. Tetrasodium Phosphonato Phosphate

30. Unii-o352864b8z

31. Tetrasodium Pyrophosphate, Anhydride

32. Sodiumpyrophosphate

33. Tetra Sodium Pyrophosphate

34. Ec 231-767-1

35. Dsstox_cid_22465

36. Dsstox_rid_80032

37. Dsstox_gsid_42465

38. Diphosphoric Acid Sodium Salt

39. Dtxsid9042465

40. Sodium Pyrophosphate [ii]

41. Sodium Diphosphate (na4(p2o7))

42. Sodium Pyrophosphate [fcc]

43. Tetrasodium Pyrophosphate Anhydrous

44. Sodium Pyrophosphate [hsdb]

45. Cs-b1771

46. Sodium Pyrophosphate [vandf]

47. Tox21_110033

48. Sodium Pyrophosphate [mart.]

49. Sodium Pyrophosphate [who-dd]

50. Tetrasodium Pyrophosphate [mi]

51. Akos015914004

52. Akos024418778

53. Diphosphoric Acid, Sodium Salt (1:4)

54. Tetrasodium Pyrophosphate [inci]

55. Ncgc00013687-01

56. Cas-7722-88-5

57. Ft-0689073

58. D05873

59. E75941

60. Q418504

61. 1004291-85-3

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 265.90 g/mol
Molecular Formula Na4O7P2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count0
Exact Mass265.87100346 g/mol
Monoisotopic Mass265.87100346 g/mol
Topological Polar Surface Area136 Ų
Heavy Atom Count13
Formal Charge0
Complexity124
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count5
4 Drug and Medication Information
4.1 Minimum/Potential Fatal Human Dose

3(?). 3= MODERATELY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) 0.5-5 G/KG, BETWEEN 1 OZ AND 1 PINT (OR 1 LB) FOR 70 KG PERSON (150 LB). ... SOME ANIMAL DATA SUGGEST THAT PYROPHOSPHATE IS CONSIDERABLY (AND UNACCOUNTABLY) MORE TOXIC THAN IMPLIED BY TOXICITY RATING OF 3.

Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-121


5 Pharmacology and Biochemistry
5.1 Metabolism/Metabolites

Pyrophosphate is hydrolyzed to the orthophosphate in the gut.

American Conference of Governmental Industrial Hygienists, Inc. Documentation of the Threshold Limit Values and Biological Exposure Indices. 6th ed. Volumes I, II, III. Cincinnati, OH: ACGIH, 1991., p. 1529


5.2 Mechanism of Action

ARSONIC ACID HERBICIDES ARE NOT GROWTH REGULATORS IN SENSE OF PLANT HORMONES. THEY ... ACT THROUGH ENZYME SYSTEMS TO INHIBIT GROWTH. THEY KILL ... SLOWLY; FIRST SYMPTOMS ARE ... CHLOROSIS, CESSATION OF GROWTH, & GRADUAL YELLOWING, THEN BROWNING FOLLOWED BY DEHYDRATION & DEATH. /ORGANOARSENICAL HERBICIDES/

Kearney, P.C., and D. D. Kaufman (eds.) Herbicides: Chemistry, Degredation and Mode of Action. Volumes 1 and 2. 2nd ed. New York: Marcel Dekker, Inc., 1975., p. 763


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