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ACTIVE PHARMA INGREDIENTS

10 API Suppliers, 3 USDMF, 2 JDMF, 5 NDC API, 7 Listed Suppliers, $ API Reference Price

10 API Suppliers
3 USDMF
2 JDMF
5 NDC API
7 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

21 FDF Dossiers, 19 Europe, 2 South Africa

21 FDF Dossiers
19 Europe
2 South Africa

RELATED EXCIPIENT COMPANIES

1 Evonik, 2 SPI Pharma, 8 DKSH, 3 Faran Shimi Pharmaceutical, 7 Gangwal Healthcare, 1 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 4 ACG Worldwide, 1 Actylis, 1 Aeon Procare, 1 Alcedo Pharmachem, 6 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 13 BASF, 13 Corel Pharma Chem, 3 DFE Pharma, 7 Gangwal Chemicals, 9 Ideal Cures Pvt Ltd, 1 Ingredion Pharma Solutions, 16 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 10 Microlex e.U, 1 Novo Excipients, 1 Pharmatrans-Sanaq, 3 Pluviaendo, 3 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 2 Qualicaps, 13 Roquette, 6 Seppic, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 10 Sigachi Industries, 2 The Dow Chemical Company, 1 Valens Pharmachem, 3 Vasa Pharmachem, 1 Vertellus

EXCIPIENTS BY APPLICATIONS

61 Coating Systems & Additives, 32 Fillers, Diluents & Binders, 31 Controlled & Modified Release, 19 Direct Compression, 19 Thickeners and Stabilizers, 18 Lubricants & Glidants, 15 Disintegrants & Superdisintegrants, 15 Granulation, 12 Film Formers & Plasticizers, 10 Taste Masking, 10 Co-Processed Excipients, 9 Empty Capsules, 5 API Stability Enhancers, 5 Coloring Agents, 4 Vegetarian Capsules, 4 Solubilizers, 4 Emulsifying Agents, 3 Rheology Modifiers, 3 Chewable & Orodispersible Aids, 2 Surfactant & Foaming Agents, 2 Topical, 1 Parenteral

DIGITAL CONTENT

1 NEWS #PharmaBuzz

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1 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

19 Finished Drug Prices

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19 Finished Drug Prices

MARKET PLACE

3 APIs

marketPlace
3 APIs

REF. STANDARDS & IMPURITIES

1 USP , 1 Others

otherSolutions
1 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 5

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

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Data Compilation #PharmaFlow

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GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

168 RELATED EXCIPIENT COMPANIES

284EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 54-21-7, Sodium 2-hydroxybenzoate, Enterosalicyl, Kerasalicyl, Clin, Alysine

Molecular Formula

C₇H₅NaO₃

Molecular Weight

160.10 g/mol

InChI Key

ABBQHOQBGMUPJH-UHFFFAOYSA-M

FDA UNII

WIQ1H85SYP

A non-steroidal anti-inflammatory agent that is less effective than equal doses of ASPIRIN in relieving pain and reducing fever. However, individuals who are hypersensitive to ASPIRIN may tolerate sodium salicylate. In general, this salicylate produces the same adverse reactions as ASPIRIN, but there is less occult gastrointestinal bleeding. (From AMA Drug Evaluations Annual, 1992, p120)

1 2D Structure

Sodium Salicylate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

sodium;2-hydroxybenzoate

2.1.2 InChI

InChI=1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1

2.1.3 InChI Key

ABBQHOQBGMUPJH-UHFFFAOYSA-M

2.1.4 Canonical SMILES

C1=CC=C(C(=C1)C(=O)[O-])O.[Na+]

2.2 Other Identifiers

2.2.1 UNII

WIQ1H85SYP

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Salicylate, Sodium

2.3.2 Depositor-Supplied Synonyms

1. 54-21-7

2. Sodium 2-hydroxybenzoate

3. Enterosalicyl

4. Kerasalicyl

5. Clin

6. Alysine

7. Salsonin

8. Benzoic Acid, 2-hydroxy-, Monosodium Salt

9. Enterosalil

10. Entrosalyl

11. Glutosalyl

12. Magsalyl

13. Aroall

14. Kerosal

15. Nadisal

16. Salisod

17. Idocyl Novum

18. Neo-salicyl

19. Natrum Salicylicum

20. Monosodium Salicylate

21. Salicylic Acid Sodium Salt

22. Diuretin

23. Parbocyl-rev

24. Sodium;2-hydroxybenzoate

25. Salicylate Sodium

26. Salicylic Acid, Sodium Salt

27. Sodium O-hydroxybenzoate

28. Salicylic Acid Sodium

29. Wiq1h85syp

30. O-hydroxybenzoic Acid, Sodium Salt

31. Chebi:9180

32. Nsc-202167

33. 90218-97-6

34. Benzoic Acid, 2-hydroxy-, Monosodium Salt, Coupled With 4-amino-1-naphthalenesulfonic Acid And Diazotized 2-(4-aminophenyl)-1h-benzimidazol-5-amine, Sodium Salt

35. Salicylic Acid Sodium Salt;2-hydroxybenzoic Acid Sodium Salt

36. Natrium Salicylat [german]

37. Ccris 6715

38. Einecs 200-198-0

39. Unii-wiq1h85syp

40. Nsc 202167

41. Sodium Salicylate [usp:jan]

42. Natrii Salicylas

43. Mfcd00002440

44. Sodium;2-carboxyphenolate

45. Sodium Salicylate, 99%

46. Spectrum2_001945

47. Spectrum3_000900

48. Spectrum4_000995

49. Spectrum5_001120

50. Dsstox_cid_1708

51. Ec 200-198-0

52. Schembl4603

53. Dsstox_rid_76287

54. Dsstox_gsid_21708

55. Kbiogr_001429

56. 90218-94-3

57. Spectrum1500533

58. Spbio_002009

59. Chembl447868

60. Sodium Salicylate [jan]

61. Dtxsid5021708

62. Sodium Salicylate (jp17/usp)

63. Sodium Salicylate [inci]

64. Hy-b0167a

65. Kbio3_001820

66. Natrum Salicylicum [hpus]

67. Sodium Salicylate [vandf]

68. Sodium Salicylate [mart.]

69. Hms1920p16

70. Hms2092g17

71. Salicylate Sodium [who-dd]

72. Sodium Salicylate [usp-rs]

73. Sodium Salicylate [who-ip]

74. Sodium Salicylate, P.a., 99.5%

75. Tox21_200411

76. 2-hydroxy Benzoic Acid, Sodium Salt

77. Ccg-39474

78. Akos003051698

79. Akos005766021

80. Cs-2008

81. Cas-54-21-7

82. Natrii Salicylas [who-ip Latin]

83. Salicylic Acid Sodium Salt [mi]

84. Sodium Salicylate [ep Monograph]

85. Ncgc00094780-01

86. Ncgc00094780-02

87. Ncgc00257965-01

88. Sodium Salicylate [usp Monograph]

89. Db-052516

90. Ft-0631235

91. C07587

92. D00566

93. D83111

94. Sodium Salicylate, Reagentplus(r), >=99.5%

95. Sodium Salicylate, Saj First Grade, >=99.5%

96. Sodium Salicylate, Tested According To Ph.eur.

97. Sodium Salicylate, Saj Special Grade, >=99.5%

98. 2,4-dimethoxyphenylboronicacid,pinacolester

99. Q414547

100. Sodium Salicylate, Vetec(tm) Reagent Grade, 99%

101. Sodium Salicylate, Meets Usp Testing Specifications

102. Sodium Salicylate, Puriss. P.a., >=99.5% (nt)

103. Sodium Salicylate, European Pharmacopoeia (ep) Reference Standard

104. Sodium Salicylate, United States Pharmacopeia (usp) Reference Standard

105. Benzoic Acid,2-hydroxy-,monosodium Salt,coupled With 4-amino-5-hydroxy-2,7-naphthalenedisulfonic Acid,diazotized 2-(4-aminophenyl)-1h-benzimidazol-5-amine And Diazotized 4-nitrobenzenamine,sodium

106. Sodium Salicylate, Puriss. P.a., Reag. Ph. Eur., 99.5-101.0% (calc. To The Dried Substance)

2.4 Create Date

2007-11-13

3 Chemical and Physical Properties

Molecular Formula	C₇H₅NaO₃
Molecular Weight	160.10 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	160.01363830 g/mol
Monoisotopic Mass	160.01363830 g/mol
Topological Polar Surface Area	60.4 Å²
Heavy Atom Count	11
Formal Charge	0
Complexity	138
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)

Cyclooxygenase Inhibitors

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)

4.2 ATC Code

N - Nervous system

N02 - Analgesics

N02B - Other analgesics and antipyretics

N02BA - Salicylic acid and derivatives

N02BA04 - Sodium salicylate

API SUPPLIERS

01

Polpharma

Poland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

Polpharma is a Polish CDMO of APIs and a significant European API producer, delivering products to companies worldwide.

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Poland

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USDMF

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CEP/COS JDMF

EU-WC NDC KDMF VMF ASMF

AUDIT

02

Transo-Pharm USA LLC

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

TransoPharm USA works in the Sourcing and Management of Active Pharmaceutical Ingredients.

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U.S.A

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF US

AUDIT

03

Rochem International Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Suppliers Night Expo

Attending

Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

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U.S.A

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

04

Pharm-RX Chemical

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

Pharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

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U.S.A

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

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05

JQC Huayin Pharmaceutical

China

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering

Not Confirmed

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USDMF

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JDMF

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NDC API

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API Reference Price

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AP","supplier":"JIANGSU PHARMA BRIDGE ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SALICYLATES & CHEMICALS ","customerCountry":"INDIA","quantity":"18000.00","actualQuantity":"18000","unit":"KGS","unitRateFc":"2.7","totalValueFC":"49106.8","currency":"USD","unitRateINR":"227.7","date":"03-Jun-2024","totalValueINR":"4099410","totalValueInUsd":"49106.8","indian_port":"Madras Sea","hs_no":"29182990","bill_no":"3808029","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"326,D-2,GREENLAND INTER-CITIESSPACE STATION,4 JINYUAN RDJIANGNING,NANJING,CHINA CN","customerAddress":"12, JEERA,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718821800,"product":"SODIUM SALICYLATE O (RAW MATERIAL FOR COSMETIC USE)","address":"509,SHAH NIHAR (WORLI) INDL.ESTAT","city":"WORLI, MUMBAI, MAHARASHTRA.","supplier":"LONGRUN(HONGKONG)INTERNATIONAL LIMI","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"VALUETREE INGREDIENTS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"800.00","actualQuantity":"800","unit":"KGS","unitRateFc":"6.2","totalValueFC":"5249.6","currency":"USD","unitRateINR":"547.8","date":"20-Jun-2024","totalValueINR":"438230.3","totalValueInUsd":"5249.6","indian_port":"JNPT","hs_no":"29182120","bill_no":"4095552","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"TEDRM1501-C1,GRAND MILENNIUM PLAZA(LOWER BLOCK),181 QUEENS ROADCENTRAL, HONG KONG","customerAddress":"509,SHAH NIHAR (WORLI) INDL.ESTAT"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1719167400,"product":"SODIUM SALICYLATE","address":"12, JEERA,","city":"SECUNDERABAD. AP","supplier":"ZHEJIANG CHEMICALS I & E CORP","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SALICYLATES & CHEMICALS ","customerCountry":"INDIA","quantity":"18000.00","actualQuantity":"18000","unit":"KGS","unitRateFc":"2.7","totalValueFC":"48714.2","currency":"USD","unitRateINR":"225.9","date":"24-Jun-2024","totalValueINR":"4066632","totalValueInUsd":"48714.2","indian_port":"Madras Sea","hs_no":"29182990","bill_no":"4150238","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO 37,QINGCHUN ROAD HANGZHOU,CHINASDNFSDNF CN","customerAddress":"12, JEERA,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1720549800,"product":"SODIUM SALICYLATE O (FOR COSMETIC USE)","address":"509,SHAH NIHAR (WORLI) INDL.ESTAT","city":"WORLI, MUMBAI, MAHARASHTRA.","supplier":"LONGRUN HONGKONG INTERNATIONAL ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"VALUETREE INGREDIENTS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"125.00","actualQuantity":"125","unit":"KGS","unitRateFc":"6.2","totalValueFC":"1014.7","currency":"USD","unitRateINR":"678.5","date":"10-Jul-2024","totalValueINR":"84816.71","totalValueInUsd":"1014.7","indian_port":"JNPT","hs_no":"29182120","bill_no":"4434575","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"RM1501-C1, GRAND MILLENNIUM PLAZA (LOWER BLOCK), 181 QUEEN\\'S ROAD CENTRAL Hong Kong","customerAddress":"509,SHAH NIHAR (WORLI) INDL.ESTAT"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724351400,"product":"SODIUM SALICYLATE 25KG 1H2\/PO:4985017492\/00020SODIUM SALICYLATE","address":"PLOT NO. 37, CHANDIVALI FARM ROAD,","city":"ANDHERI EAST,MAHARASHTRA","supplier":"BASF","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"BASF","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"49","totalValueFC":"1237.9","currency":"USD","unitRateINR":"4153.4","date":"23-Aug-2024","totalValueINR":"103835.19","totalValueInUsd":"1237.9","indian_port":"Bombay Air","hs_no":"29182120","bill_no":"5216574","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"ELASTOGRANSTRABE 60SDNFLEMFORDE DE","customerAddress":"PLOT NO. 37, CHANDIVALI FARM ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732905000,"product":"NATRIUMSALICYLAT 25KG 1H2\/PO:4986563731\/00020SODIUM SALICYLATE","address":"PLOT NO. 37, CHANDIVALI FARM ROAD,","city":"ANDHERI EAST,MAHARASHTRA","supplier":"BASF","supplierCountry":"GERMANY","foreign_port":"N\/A","customer":"BASF","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"50.5","totalValueFC":"1277.4","currency":"USD","unitRateINR":"4311.9","date":"30-Nov-2024","totalValueINR":"107797.05","totalValueInUsd":"1277.4","indian_port":"Bombay Air","hs_no":"29182120","bill_no":"6986876","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"ELASTOGRANSTRABE 60 -49448 LEMFORDE , GERMANY Germany","customerAddress":"PLOT NO. 37, CHANDIVALI FARM ROAD,"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

10 API Suppliers

3 USDMF

2 JDMF

5 NDC API

7 Listed Suppliers

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

21 FDF Dossiers

19 Europe

2 South Africa

RELATED EXCIPIENT COMPANIES

1 Evonik

2 SPI Pharma

8 DKSH

3 Faran Shimi Pharmaceutical

7 Gangwal Healthcare

1 Nanjing Well Pharmaceutical

1 Pfanstiehl

4 ACG Worldwide

1 Actylis

1 Aeon Procare

1 Alcedo Pharmachem

6 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

13 BASF

13 Corel Pharma Chem

3 DFE Pharma

7 Gangwal Chemicals

9 Ideal Cures Pvt Ltd

1 Ingredion Pharma Solutions

16 Kerry

3 Kima Chemical

6 Lonza Capsugel

10 Microlex e.U

1 Novo Excipients

1 Pharmatrans-Sanaq

3 Pluviaendo

3 Prachin Chemical

1 Qianhao Chemical (Hebei) Co., Ltd

2 Qualicaps

13 Roquette

6 Seppic

4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

10 Sigachi Industries

2 The Dow Chemical Company

1 Valens Pharmachem

3 Vasa Pharmachem

1 Vertellus

EXCIPIENTS BY APPLICATIONS

61 Coating Systems & Additives

32 Fillers, Diluents & Binders

31 Controlled & Modified Release

19 Direct Compression

19 Thickeners and Stabilizers

18 Lubricants & Glidants

15 Disintegrants & Superdisintegrants

15 Granulation

12 Film Formers & Plasticizers

10 Taste Masking

10 Co-Processed Excipients

9 Empty Capsules

5 API Stability Enhancers

5 Coloring Agents

4 Vegetarian Capsules

4 Solubilizers

4 Emulsifying Agents

3 Rheology Modifiers

3 Chewable & Orodispersible Aids

2 Surfactant & Foaming Agents

2 Topical

1 Parenteral

DIGITAL CONTENT

1 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

19 Finished Drug Prices