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Chemistry

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Also known as: 7758-29-4, Pentasodium triphosphate, Sodium triphosphate, Stpp, Pentasodium tripolyphosphate, Triphosphoric acid, pentasodium salt
Molecular Formula
Na5O10P3
Molecular Weight
367.86  g/mol
InChI Key
HWGNBUXHKFFFIH-UHFFFAOYSA-I
FDA UNII
9SW4PFD2FZ

Sodium Tripolyphosphate
Sodium tripolyphosphate is an inorganic compound with formula Na5P3O10 and the sodium salt of the polyphosphate penta-anion. It is used as a component of a wide range domestic and industrial products, particularly detergents.
1 2D Structure

Sodium Tripolyphosphate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
pentasodium;[oxido(phosphonatooxy)phosphoryl] phosphate
2.1.2 InChI
InChI=1S/5Na.H5O10P3/c;;;;;1-11(2,3)9-13(7,8)10-12(4,5)6/h;;;;;(H,7,8)(H2,1,2,3)(H2,4,5,6)/q5*+1;/p-5
2.1.3 InChI Key
HWGNBUXHKFFFIH-UHFFFAOYSA-I
2.1.4 Canonical SMILES
[O-]P(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+]
2.2 Other Identifiers
2.2.1 UNII
9SW4PFD2FZ
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Pentapotassium Triphosphate

2. Potassium Triphosphate

3. Sodium Triphosphate

4. Sodium Tripolyphosphate Anhydrous

5. Tetrasodium Tripolyphosphate

6. Triphosphate

7. Triphosphoric Acid

8. Triphosphoric Acid, 99tc-labeled Cpd

9. Triphosphoric Acid, Pentapotassium Salt

10. Triphosphoric Acid, Pentasodium Salt

11. Triphosphoric Acid, Sodium Salt

12. Triphosphoric Acid, Sodium, Potassium Salt

13. Tripolyphosphate

2.3.2 Depositor-Supplied Synonyms

1. 7758-29-4

2. Pentasodium Triphosphate

3. Sodium Triphosphate

4. Stpp

5. Pentasodium Tripolyphosphate

6. Triphosphoric Acid, Pentasodium Salt

7. Triphosphoric Acid, Sodium Salt

8. 9sw4pfd2fz

9. Sodium Tripolyphosphate Anhydrous

10. Thermphos

11. Mfcd00003514

12. Pentasodium;[oxido(phosphonatooxy)phosphoryl] Phosphate

13. Armofos

14. Polygon

15. Tripoly

16. Rhodiaphos Lv

17. Thermphos N

18. Empiphos Stp-d

19. Thermphos Spr

20. Thermphos L 50

21. Caswell No. 799

22. Natriumtripolyphosphat

23. Natriumtripolyphosphat [german]

24. Sodium Phosphate (na5p3o10)

25. Hsdb 1099

26. Sodium Tripolyphosphate, Anhydrous

27. Sodium Triphosphate (na5p3o10)

28. Einecs 231-838-7

29. Unii-9sw4pfd2fz

30. Sodium Tripolyphosphate (na5p3o10)

31. Epa Pesticide Chemical Code 076404

32. Na5p3o10

33. S 400

34. Ec 231-838-7

35. Dtxsid9036307

36. Sodium Tripolyphosphate [mi]

37. Sodium Triphosphate (na5(p3o10))

38. Akos015902309

39. Akos015951376

40. Db11493

41. Pentasodium Triphosphate [inci]

42. Triphosphoric Acid, Sodium Salt (1:5)

43. Pentasodium Tripolyphosphate [hsdb]

44. Sodium Tripolyphosphate [green Book]

45. Ft-0689070

46. Sodium Tripolyphosphate, Technical Grade, 85%

47. Q29145

48. Sodium Triphosphate Pentabasic, Purum P.a., >=98.0% (t)

49. Sodium Triphosphate Pentabasic, Vetec(tm) Reagent Grade, 98%

50. Sodium Tripolyphosphate, Saj First Grade, 56.0-61.0% P2o5 Basis

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 367.86 g/mol
Molecular Formula Na5O10P3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count10
Rotatable Bond Count2
Exact Mass367.8192786 g/mol
Monoisotopic Mass367.8192786 g/mol
Topological Polar Surface Area185 Ų
Heavy Atom Count18
Formal Charge0
Complexity241
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count6
4 Drug and Medication Information
4.1 Therapeutic Uses

MEDICATION (VET): USED IN WATER SOL DISPERSIBLE PREMIXES OR IN LIQ FEED SUPPLEMENTS AS PHOSPHORUS SOURCE FOR CATTLE. ... AS CALCIUM & MAGNESIUM CHELATOR, IT NOT ONLY FINDS WIDESPREAD USE IN WATER SOFTENING BUT AS ADJUNCTIVE ORAL PROPHYLAXIS AGAINST SUCH MINERAL BASED URINARY CALCULI IN CATS.

Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 548


5 Pharmacology and Biochemistry
5.1 Absorption, Distribution and Excretion

If ingested in large amounts nausea, vomiting and diarrhea are probable. Thought to be hydrolyzed to (ortho)phosphates before absorption. If appreciable amounts of the intact polymer are absorbed from the alimentary tract, hypocalcemic tetany may be a danger due to the binding (chelation) of ionized calcium. Hypocalcemic tetany apparently occurred in one ingestion episode. /Tripolyphosphate/

Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-121


5.2 Metabolism/Metabolites

THOUGHT TO BE HYDROLYZED TO (ORTHO)PHOSPHATES BEFORE ABSORPTION. /TRIPOLYPHOSPHATE/

Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-121


In the body, phosphorus is converted to phosphates. /Phosphorus/

Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 2122


5.3 Mechanism of Action

The effects of condensed phosphate ( ... sodium tripolyphosphate ... ) on the growth of Streptococcus mutans, sugar metabolism in vitro, and S mutans-induced caries of hamsters were studied. All condensed phosphates depressed the growth of S mutans. This growth inhibition was reversed by divalent metal ions. Thus, the chelating capacity of condensed phosphate is responsible for their antibacterial actions. Condensed phosphates depressed lactate production from glucose and sucrose by the S mutans.

PMID:7308964 Shibata H; Fukuoka Igaku Zasshi 72 (6): 379-91 (1981)


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Sodium Tripolyphosphate

About the Company : Valaji PharmaChem is an ISO certified and a leading name in the field of Fine/ Specialty high purity chemicals with large manufacturing facilities located at Padra, Baroda, Gujarat...

Valaji PharmaChem is an ISO certified and a leading name in the field of Fine/ Specialty high purity chemicals with large manufacturing facilities located at Padra, Baroda, Gujarat, INDIA. We are a bulk manufacturer of high purity fine chemicals, in compliance with Reagent, Pharmacopoeia and various Food Grade standards, for the pharmaceutical, nutraceutical, veterinary, food, chemical analysis and other specialty markets. We have been extensively investing in state-of- the-art manufacturing infrastructure. Over the years we have developed multiple assets to produce a large range of lab/fine/specialty/ rare and research chemicals.
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ABOUT THIS PAGE

Sodium Tripolyphosphate Manufacturers

A Sodium Tripolyphosphate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sodium Tripolyphosphate, including repackagers and relabelers. The FDA regulates Sodium Tripolyphosphate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sodium Tripolyphosphate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Sodium Tripolyphosphate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Sodium Tripolyphosphate Suppliers

A Sodium Tripolyphosphate supplier is an individual or a company that provides Sodium Tripolyphosphate active pharmaceutical ingredient (API) or Sodium Tripolyphosphate finished formulations upon request. The Sodium Tripolyphosphate suppliers may include Sodium Tripolyphosphate API manufacturers, exporters, distributors and traders.

click here to find a list of Sodium Tripolyphosphate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sodium Tripolyphosphate GMP

Sodium Tripolyphosphate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sodium Tripolyphosphate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sodium Tripolyphosphate GMP manufacturer or Sodium Tripolyphosphate GMP API supplier for your needs.

Sodium Tripolyphosphate CoA

A Sodium Tripolyphosphate CoA (Certificate of Analysis) is a formal document that attests to Sodium Tripolyphosphate's compliance with Sodium Tripolyphosphate specifications and serves as a tool for batch-level quality control.

Sodium Tripolyphosphate CoA mostly includes findings from lab analyses of a specific batch. For each Sodium Tripolyphosphate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sodium Tripolyphosphate may be tested according to a variety of international standards, such as European Pharmacopoeia (Sodium Tripolyphosphate EP), Sodium Tripolyphosphate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sodium Tripolyphosphate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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