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Sodium Tungstate

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Also known as: 13472-45-2, Disodium tungstate, Sodium wolframate, Sodium tungstate(vi), Disodium dioxido(dioxo)tungsten, Tungstate, sodium

Molecular Formula

Na₂O₄W

Molecular Weight

293.82 g/mol

InChI Key

XMVONEAAOPAGAO-UHFFFAOYSA-N

FDA UNII

64LRH4405G

1 2D Structure

Sodium Tungstate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

disodium;dioxido(dioxo)tungsten

2.1.2 InChI

InChI=1S/2Na.4O.W/q2*+1;;;2*-1;

2.1.3 InChI Key

XMVONEAAOPAGAO-UHFFFAOYSA-N

2.1.4 Canonical SMILES

[O-][W](=O)(=O)[O-].[Na+].[Na+]

2.2 Other Identifiers

2.2.1 UNII

64LRH4405G

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Sodium Tungstate Dihydrate

2. Sodium Tungstate(vi)

3. Sodium Tungstate(vi) Dihydrate

4. Sodium Tungstate(vi), 181w-labeled

2.3.2 Depositor-Supplied Synonyms

1. 13472-45-2

2. Disodium Tungstate

3. Sodium Wolframate

4. Sodium Tungstate(vi)

5. Disodium Dioxido(dioxo)tungsten

6. Tungstate, Sodium

7. Sodium Tungsten Oxide (na2wo4)

8. Tungstic Acid (h2wo4), Disodium Salt

9. Tungstic Acid, Disodium Salt

10. Disodium;dioxido(dioxo)tungsten

11. Tungstate (wo42-), Disodium, (t-4)-

12. 126752-51-0

13. 64lrh4405g

14. Disodium Wolframate

15. Sodium Tungstate (na2wo4)

16. Disodium Tungstate (na2wo4)

17. Ccris 5814

18. Sodium Tungstate (na2(wo4))

19. Disodium Tetraoxatungstate (2-)

20. Disodium Tetraoxotungstate (2-)

21. Hsdb 5057

22. Sodium Tungstate(vi) (na2wo4)

23. Einecs 236-743-4

24. Unii-64lrh4405g

25. Sodiumtungstate(vi)

26. Sodium Tungstate (vi)

27. Na2wo4

28. Disodium Tetraoxotungstate

29. Tungstate (w10o324-), Sodium (1:4)

30. Tungstate (wo42-), Disodium, (beta-4)-

31. Tungastate (wo4(2-)), Disodium, (t-4)-

32. Ec 236-743-4

33. Sodium Tetraoxotungstate(vi)

34. Disodium Tetraoxatungstate(2-)

35. Disodium Tetraoxotungstate(2-)

36. Chebi:63940

37. Sodium Tungstate(vi) [mi]

38. Akos030227979

39. Gs-3112

40. Ns00093533

41. Q418410

42. Tungstate (wo42-), Sodium (1:2), (t-4)-

43. Tungsten(4+) Ion Disodium Dihydroxide Dioxidandiide

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	Na₂O₄W
Molecular Weight	293.82 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	0
Exact Mass	g/mol
Monoisotopic Mass	g/mol
Topological Polar Surface Area	80.3
Heavy Atom Count	7
Formal Charge	0
Complexity	62.2
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3

4 Drug and Medication Information

4.1 Minimum/Potential Fatal Human Dose

3. 3= MODERATELY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) IS 0.5-5 G/KG, BETWEEN 1 OUNCE & 1 PINT (OR 1 POUND) FOR 70 KG PERSON (150 LB). /TUNGSTEN & ITS SALTS/

Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. II-102

5 Pharmacology and Biochemistry

5.1 Absorption, Distribution and Excretion

RATS...FED...100 DAYS ON DIETS /INCL SODIUM TUNGSTATE/... PRINCIPAL SITES OF DEPOSITION WERE BONE & SPLEEN WITH TRACE QUANTITIES (LESS THAN 1.0 MG %...) IN KIDNEY & LIVER, & IN SOME ANIMALS IN BLOOD, LUNG, MUSCLE & TESTES.

Friberg, L., G.R. Nordberg, and V.B. Vouk. Handbook on the Toxicology of Metals. New York: Elsevier North Holland, 1979., p. 640

...AFTER ORAL ADMIN OF SODIUM TUNGSTATE...AFTER 1 DAY, GREATEST CONCN IN SPLEEN FOLLOWED BY KIDNEY, PELT, BONE & LIVER. ...FOLLOWING ADMIN...BY GASTRIC INTUBATION IN RATS...HIGHEST CONCN IN KIDNEY FOLLOWED BY BONE & SPLEEN.

Friberg, L., G.R. Nordberg, and V.B. Vouk. Handbook on the Toxicology of Metals. New York: Elsevier North Holland, 1979., p. 640

ALMOST 1/2 OF INGESTED DOSE...OF A SOL SALT...RAPIDLY ABSORBED IN...ANIMAL MODELS... MOST OF ABSORBED TUNGSTEN...RAPIDLY EXCRETED IN URINE. SMALL AMT... RETAINED WAS TRANSFERRED IN PART FROM PLASMA TO RED BLOOD CELLS & DISTRIBUTED MAINLY TO SPLEEN, KIDNEY, & BONE. /SOL W SALT/

Friberg, L., G.R. Nordberg, and V.B. Vouk. Handbook on the Toxicology of Metals. New York: Elsevier North Holland, 1979., p. 637

FOLLOWING IV ADMIN (181)W SODIUM TUNGSTATE IN 2 BEAGLE DOGS, MOST OF ACTIVITY WAS FOUND IN PLASMA DURING 1ST 24 HR, WITH AVG PLASMA TO RED CELL RATIO 3:1, SUGGESTING BINDING OF TUNGSTEN TO CELL SURFACE RATHER THAN PENETRATION OF CELL MEMBRANE. ...SUGGESTED THAT W INCORPORATION INTO RED CELLS OCCURS @ SITES OF HEMATOPOIESIS.

Friberg, L., G.R. Nordberg, and V.B. Vouk. Handbook on the Toxicology of Metals. New York: Elsevier North Holland, 1979., p. 641

For more Absorption, Distribution and Excretion (Complete) data for SODIUM TUNGSTATE (8 total), please visit the HSDB record page.

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