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1. 2-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)chalcone
2. Solon
3. Su 88
4. Su-88
1. 64506-49-6
2. Solon
3. Su-88
4. Sofalcona
5. Sofalconum
6. Sofalcone [inn:jan]
7. 153175-87-2
8. Sofalcone [mi]
9. Sofalcone (jan)
10. Sofalcone [inn]
11. Sofalcone [jan]
12. Sofalcone [mart.]
13. Sofalcone [who-dd]
14. (5-((3-methyl-2-butenyl)oxy)-2-(p-((3-methyl-2-butenyl)oxy)cinnamoyl)phenoxy)acetic Acid
15. 2b668tjx8e
16. Acetic Acid, 2-(5-((3-methyl-2-buten-1-yl)oxy)-2-((2e)-3-(4-((3-methyl-2-buten-1-yl)oxy)phenyl)-1-oxo-2-propen-1-yl)phenoxy)-
17. Ncgc00159481-02
18. Dsstox_cid_3586
19. Isoprenyl Chalcone
20. Dsstox_rid_77093
21. Dsstox_gsid_23586
22. 2-[5-(3-methylbut-2-enoxy)-2-[(e)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-2-enoyl]phenoxy]acetic Acid
23. Sofalconum [latin]
24. Sofalcona [spanish]
25. (e)-2-(5-((3-methylbut-2-en-1-yl)oxy)-2-(3-(4-((3-methylbut-2-en-1-yl)oxy)phenyl)acryloyl)phenoxy)acetic Acid
26. {5-[(3-methylbut-2-en-1-yl)oxy]-2-[(2e)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl]phenoxy}acetic Acid
27. Cas-64506-49-6
28. Solon (tn)
29. Brn 2191482
30. Unii-2b668tjx8e
31. Tofalcone
32. Lavin
33. 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)chalcone
34. Schembl24786
35. 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy) Chalcone
36. Chembl1441961
37. Dtxsid50860797
38. Chebi:135732
39. Bcp12009
40. Hy-b2184
41. Zinc3831462
42. Tox21_111705
43. Mfcd00868207
44. S5450
45. Akos015895236
46. Tox21_111705_1
47. Ccg-269238
48. Cs-7893
49. Db05197
50. Ks-1141
51. Ncgc00159481-03
52. Ac-22578
53. Acetic Acid, (5((3-methyl-2-butenyl)oxy)-2-(3-(4-((3-methyl-2-butenyl)oxy)phenyl)-1-oxo-2-propenyl)phenoxy)-
54. D01956
55. D70405
56. 506s496
57. A834791
58. Q15410187
59. 2'-carboxymethoxy-4,4'-bis(3-methylbut-2-enyloxy)chalcone Sofalcone
60. ({5-[(3-methylbut-2-en-1-yl)oxy]-2-[(2e)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl]phenyl}oxy)acetic Acid
61. (e)-2-(5-(3-methylbut-2-enyloxy)-2-(3-(4-(3-methylbut-2-enyloxy)phenyl)acryloyl)phenoxy)acetic Acid
62. 2-(5-((3-methylbut-2-en-1-yl)oxy)-2-(3-(4-((3-methylbut-2-en-1-yl)oxy)phenyl)acryloyl)phenoxy)acetic Acid
63. 2-[5-(3-methylbut-2-enoxy)-2-[(e)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-2-enoyl]phenoxy]acetic Acid;sofalcone
64. 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]-acetic Acid
65. 2-{5-[(3-methylbut-2-en-1-yl)oxy]-2-(3-{4-[(3-methylbut-2-en-1- Yl)oxy]phenyl}prop-2-enoyl)phenoxy}acetic Acid
66. 2-{5-[(3-methylbut-2-en-1-yl)oxy]-2-[(2e)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl]phenoxy}acetic Acid
67. Acetic Acid,[5-[(3-methyl-2-butenyl)oxy]-2-[3-[4-[(3-methyl-2-butenyl)oxy]phenyl]-1-oxo-2-propenyl]phenoxy]-
| Molecular Weight | 450.5 g/mol |
|---|---|
| Molecular Formula | C27H30O6 |
| XLogP3 | 6.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 12 |
| Exact Mass | 450.20423867 g/mol |
| Monoisotopic Mass | 450.20423867 g/mol |
| Topological Polar Surface Area | 82.1 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 706 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in gastroenteritis and ulcers.
Anti-Ulcer Agents
Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief. (See all compounds classified as Anti-Ulcer Agents.)
Sofalcone has been reported to have an anti-bacterial effect on H. pylori and the inhibitory effects against the pathogenic factor of H. pylori in addition to the mucosal protective effect due to the inhibition of prostaglandins degradation enzyme. Sofalcone has a direct bactericidal effect on H pylori, anti-urease activity and reduces the adhesion of this organism to gastric epithelial cells
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ABOUT THIS PAGE
A Sofalcone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sofalcone, including repackagers and relabelers. The FDA regulates Sofalcone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sofalcone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Sofalcone manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Sofalcone supplier is an individual or a company that provides Sofalcone active pharmaceutical ingredient (API) or Sofalcone finished formulations upon request. The Sofalcone suppliers may include Sofalcone API manufacturers, exporters, distributors and traders.
click here to find a list of Sofalcone suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.
The Sofalcone Drug Master File in Japan (Sofalcone JDMF) empowers Sofalcone API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).
PMDA reviews the Sofalcone JDMF during the approval evaluation for pharmaceutical products. At the time of Sofalcone JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.
click here to find a list of Sofalcone suppliers with JDMF on PharmaCompass.
Sofalcone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Sofalcone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sofalcone GMP manufacturer or Sofalcone GMP API supplier for your needs.
A Sofalcone CoA (Certificate of Analysis) is a formal document that attests to Sofalcone's compliance with Sofalcone specifications and serves as a tool for batch-level quality control.
Sofalcone CoA mostly includes findings from lab analyses of a specific batch. For each Sofalcone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Sofalcone may be tested according to a variety of international standards, such as European Pharmacopoeia (Sofalcone EP), Sofalcone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sofalcone USP).
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