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Also known as: Cvn424, 2254706-21-1, Xo01711urg, Unii-xo01711urg, Chembl4778540, Solengepras (usan)

Molecular Formula

C₂₄H₂₉F₂N₅O₃

Molecular Weight

473.5 g/mol

InChI Key

HSWVJQBEXRKOBZ-QGZVFWFLSA-N

FDA UNII

XO01711URG

CVN-424 is under investigation in clinical trial NCT06006247 (Early Parkinson's Disease Monotherapy With CVN424).

1 2D Structure

Solengepras

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-[2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-[[(3R)-oxolan-3-yl]amino]-7,8-dihydro-5H-pyrido[3,4-b]pyrazin-6-yl]ethanone

2.1.2 InChI

InChI=1S/C24H29F2N5O3/c1-15(32)31-10-6-20-21(13-31)28-23(27-17-7-11-33-14-17)24(29-20)30-8-4-18(5-9-30)34-22-3-2-16(25)12-19(22)26/h2-3,12,17-18H,4-11,13-14H2,1H3,(H,27,28)/t17-/m1/s1

2.1.3 InChI Key

HSWVJQBEXRKOBZ-QGZVFWFLSA-N

2.2 Other Identifiers

2.2.1 UNII

XO01711URG

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. Cvn424

2. 2254706-21-1

3. Xo01711urg

4. Unii-xo01711urg

5. Chembl4778540

6. Solengepras (usan)

7. 1-[2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-[[(3r)-oxolan-3-yl]amino]-7,8-dihydro-5h-pyrido[3,4-b]pyrazin-6-yl]ethanone

8. Compound 6i [pmid: 33861086]

9. Solengepras [usan]

10. Ethanone, 1-(2-(4-(2,4-difluorophenoxy)-1-piperidinyl)-7,8-dihydro-3-(((3r)-tetrahydro-3-furanyl)amino)pyrido(3,4-b)pyrazin-6(5h)-yl)-

11. Compound 6i (pmid: 33861086)

12. Solengepras

13. 1-(2-(4-(2,4-difluorophenoxy)piperidin-1-yl)-3-(((3r)-oxolan-3-yl)amino)-7,8-dihydro-5h-pyrido(3,4-b)pyrazin-6-yl)ethanone

14. Ethanone, 1-[2-[4-(2,4-difluorophenoxy)-1-piperidinyl]-7,8-dihydro-3-[[(3r)-tetrahydro-3-furanyl]amino]pyrido[3,4-b]pyrazin-6(5h)-yl]-

15. Solangepras [inn]

16. Schembl20584477

17. Gtpl11514

18. Bdbm50582450

19. Akos040759781

20. At37427

21. Hy-134661a

22. Ms-28775

23. Cs-0163733

24. D12980

25. Z3664677849

26. 1-(2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-{[(3r)-oxanolan-3-yl]amino}-7,8-dihydropyrido[3,4-b]pyrazin-6(5h)-yl)ethan-1-one

27. 1-{2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-{[(3r)-oxolan-3-yl]amino}-7,8-dihydropyrido[3,4-b]pyrazin-6(5h)-yl}ethan-1-one

28. X7t

2.4 Create Date

2019-03-16

3 Chemical and Physical Properties

Molecular Formula	C₂₄H₂₉F₂N₅O₃
Molecular Weight	473.5 g/mol
XLogP3	2.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	5
Exact Mass	Da
Monoisotopic Mass	Da
Topological Polar Surface Area	79.8
Heavy Atom Count	34
Formal Charge	0
Complexity	698
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1