Find Solnatide manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 259206-53-6, Solnatide [inn], Tip-peptide, Unii-17zs80333g, Ap301 peptide, Ap-301
Molecular Formula
C82H119N23O27S2
Molecular Weight
1923.1  g/mol
InChI Key
LKVFMOMQYXIFRK-KSVAIKAXSA-N

Solnatide
Solnatide has been used in trials studying the treatment of Acute Lung Injury.
1 2D Structure

Solnatide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(3S,6S,9S,12S,18S,21S,27S,30S,33S,36S,42R,47R,50S,53S,56S)-42-amino-3-(4-aminobutyl)-36-(3-amino-3-oxopropyl)-33-(3-carbamimidamidopropyl)-9,18,30-tris(2-carboxyethyl)-27-[(1R)-1-hydroxyethyl]-50-[(4-hydroxyphenyl)methyl]-53-(1H-indol-3-ylmethyl)-6,12-dimethyl-2,5,8,11,14,17,20,26,29,32,35,38,41,49,52,55-hexadecaoxo-44,45-dithia-1,4,7,10,13,16,19,25,28,31,34,37,40,48,51,54-hexadecazatricyclo[54.3.0.021,25]nonapentacontane-47-carboxylic acid
2.1.2 InChI
InChI=1S/C82H119N23O27S2/c1-40-67(117)95-52(23-27-64(113)114)71(121)93-41(2)68(118)99-54(13-6-7-29-83)79(129)104-31-9-15-58(104)78(128)101-56(34-44-35-89-48-12-5-4-11-46(44)48)76(126)100-55(33-43-17-19-45(107)20-18-43)75(125)102-57(81(131)132)39-134-133-38-47(84)69(119)90-37-62(110)94-51(21-25-60(85)108)73(123)96-49(14-8-30-88-82(86)87)72(122)97-53(24-28-65(115)116)74(124)103-66(42(3)106)80(130)105-32-10-16-59(105)77(127)98-50(22-26-63(111)112)70(120)91-36-61(109)92-40/h4-5,11-12,17-20,35,40-42,47,49-59,66,89,106-107H,6-10,13-16,21-34,36-39,83-84H2,1-3H3,(H2,85,108)(H,90,119)(H,91,120)(H,92,109)(H,93,121)(H,94,110)(H,95,117)(H,96,123)(H,97,122)(H,98,127)(H,99,118)(H,100,126)(H,101,128)(H,102,125)(H,103,124)(H,111,112)(H,113,114)(H,115,116)(H,131,132)(H4,86,87,88)/t40-,41-,42+,47-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,66-/m0/s1
2.1.3 InChI Key
LKVFMOMQYXIFRK-KSVAIKAXSA-N
2.1.4 Canonical SMILES
CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N3CCCC3C(=O)NC(C(=O)NCC(=O)N1)CCC(=O)O)C(C)O)CCC(=O)O)CCCNC(=N)N)CCC(=O)N)N)C(=O)O)CC4=CC=C(C=C4)O)CC5=CNC6=CC=CC=C65)CCCCN)C)CCC(=O)O
2.1.5 Isomeric SMILES
C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N3CCC[C@H]3C(=O)N[C@H](C(=O)NCC(=O)N1)CCC(=O)O)[C@@H](C)O)CCC(=O)O)CCCNC(=N)N)CCC(=O)N)N)C(=O)O)CC4=CC=C(C=C4)O)CC5=CNC6=CC=CC=C65)CCCCN)C)CCC(=O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Ap301 Peptide

2. Tip-peptide

2.2.2 Depositor-Supplied Synonyms

1. 259206-53-6

2. Solnatide [inn]

3. Tip-peptide

4. Unii-17zs80333g

5. Ap301 Peptide

6. Ap-301

7. 17zs80333g

8. Cys-gly-gln-arg-glu-thr-pro-glu-gly-ala-glu-ala-lys-pro-trp-tyr-cys Cyclic (1->17)-disulfide

9. L-cysteine, L-cysteinylglycyl-l-glutaminyl-l-arginyl-l-alpha-glutamyl-l-threonyl-l-prolyl-l-alpha-glutamylglycyl-l-alanyl-l-alpha-glutamyl-l-alanyl-l-lysyl-l-prolyl-l-tryptophyl-l-tyrosyl-, Cyclic (1->17)-disulfide

2.3 Create Date
2015-09-11
3 Chemical and Physical Properties
Molecular Weight 1923.1 g/mol
Molecular Formula C82H119N23O27S2
XLogP3-10.7
Hydrogen Bond Donor Count27
Hydrogen Bond Acceptor Count32
Rotatable Bond Count27
Exact Mass1921.8087180 g/mol
Monoisotopic Mass1921.8087180 g/mol
Topological Polar Surface Area861 Ų
Heavy Atom Count134
Formal Charge0
Complexity4170
Isotope Atom Count0
Defined Atom Stereocenter Count16
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Solnatide Manufacturers

A Solnatide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Solnatide, including repackagers and relabelers. The FDA regulates Solnatide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Solnatide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Solnatide Suppliers

A Solnatide supplier is an individual or a company that provides Solnatide active pharmaceutical ingredient (API) or Solnatide finished formulations upon request. The Solnatide suppliers may include Solnatide API manufacturers, exporters, distributors and traders.

Solnatide GMP

Solnatide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Solnatide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Solnatide GMP manufacturer or Solnatide GMP API supplier for your needs.

Solnatide CoA

A Solnatide CoA (Certificate of Analysis) is a formal document that attests to Solnatide's compliance with Solnatide specifications and serves as a tool for batch-level quality control.

Solnatide CoA mostly includes findings from lab analyses of a specific batch. For each Solnatide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Solnatide may be tested according to a variety of international standards, such as European Pharmacopoeia (Solnatide EP), Solnatide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Solnatide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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