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    Also known as: 53251-94-8, Dicetel, Pinaverium bromide [inn], Lat-1717, Pinaverium bromide (inn), Morpholinium, 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]-, bromide (1:1)
    Molecular Formula
    C26H41Br2NO4
    Molecular Weight
    591.4  g/mol
    InChI Key
    IKGXLCMLVINENI-UHFFFAOYSA-M
    Pinaverium Bromide
    Pinaverium Bromide is an orally available bromide salt form of pinaverium, a calcium channel blocker (CCB) with antispasmodic activity. Upon oral administration, pinaverium blocks the voltage-dependent calcium channels and inhibits calcium ion influx into the smooth muscle cells located in the gastrointestinal (GI) tract. This prevents smooth muscle contraction and relaxes the GI tract. In addition, pinaverium may both reduce bowel uptake of and facilitate the function of locally active, co-administered drugs.
    1 2D Structure

    Pinaverium Bromide

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethyl-2-bicyclo[3.1.1]heptanyl)ethoxy]ethyl]morpholin-4-ium;bromide
    2.1.2 InChI
    InChI=1S/C26H41BrNO4.BrH/c1-26(2)21-6-5-19(22(26)16-21)7-11-31-12-8-28(9-13-32-14-10-28)18-20-15-24(29-3)25(30-4)17-23(20)27;/h15,17,19,21-22H,5-14,16,18H2,1-4H3;1H/q+1;/p-1
    2.1.3 InChI Key
    IKGXLCMLVINENI-UHFFFAOYSA-M
    2.1.4 Canonical SMILES
    CC1(C2CCC(C1C2)CCOCC[N+]3(CCOCC3)CC4=CC(=C(C=C4Br)OC)OC)C.[Br-]
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. 4-(6-bromoveratryl)-4-(2-(2-(6,6-dimethyl-2-norpinyl)ethoxy)ethyl)morpholinium Bromide

    2. Dicetel

    3. Eldicet

    4. Pinaverium

    2.2.2 Depositor-Supplied Synonyms

    1. 53251-94-8

    2. Dicetel

    3. Pinaverium Bromide [inn]

    4. Lat-1717

    5. Pinaverium Bromide (inn)

    6. Morpholinium, 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]-, Bromide (1:1)

    7. Pinaverii Bromidum

    8. 4-(2-bromo-4,5-dimethoxybenzyl)-4-(2-(2-(6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethoxy)ethyl)morpholin-4-ium Bromide

    9. Bromuro De Pinaverio

    10. Bromure De Pinaverium

    11. Lat 1717

    12. Pinaverii Bromidum [inn-latin]

    13. Bromure De Pinaverium [inn-french]

    14. Bromuro De Pinaverio [inn-spanish]

    15. 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethyl-2-bicyclo[3.1.1]heptanyl)ethoxy]ethyl]morpholin-4-ium;bromide

    16. 4-(6-bromoveratryl)-4-(2-(2-(6,6-dimethyl-2-norpinyl)ethoxy)ethyl)morpholinium Bromide

    17. Ncgc00181763-01

    18. Einecs 258-450-0

    19. 7scf54h12j

    20. Unii-7scf54h12j

    21. Pinaveriumbromide-d4

    22. Dsstox_cid_28540

    23. Dsstox_rid_82812

    24. Dsstox_gsid_48614

    25. Schembl25474

    26. Morpholinium, 4-(2-bromo-4,5-dimethoxy)benzyl-4-(2-(2-(6,6-dimethyl-2-norpinyl)ethoxy)ethyl)-, Bromide

    27. Chembl1909298

    28. Dtxsid2048614

    29. 4-[(2-bromo-4,5-dimethoxy-phenyl)methyl]-4-[2-[2-[(1s,5s)-6,6-dimethylnorpinan-2-yl]ethoxy]ethyl]morpholin-4-ium Bromide

    30. Bcp21168

    31. Tox21_112949

    32. Mfcd01713435

    33. Akos015918115

    34. Gs-6842

    35. 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]-hept-2-yl)ethoxy]ethyl]morpholinium Bromide

    36. Cas-53251-94-8

    37. Hy-111613

    38. Cs-0088569

    39. Ft-0673906

    40. P2753

    41. D07094

    42. Lat 1717; Lat-1717; Lat1717

    43. A870784

    44. Q27268790

    45. 4-(2-bromo-4,5-dimethoxybenzyl)-4-{2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl}morpholin-4-ium Bromide

    46. 4-[(2-bromo-4,5-dimethoxy-phenyl)methyl]-4-[2-[2-(6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]-1-oxa-4-azoniacyclohexane Bromide

    47. 4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-(2-{6,6-dimethylbicyclo[3.1.1]heptan-2-yl}ethoxy)ethyl]morpholin-4-ium Bromide

    48. Morpholinium,4-[(2-bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]-, Bromide

    2.3 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 591.4 g/mol
    Molecular Formula C26H41Br2NO4
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count10
    Exact Mass591.13818 g/mol
    Monoisotopic Mass589.14023 g/mol
    Topological Polar Surface Area36.9 Ų
    Heavy Atom Count33
    Formal Charge0
    Complexity596
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count3
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Calcium Channel Blockers

    A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)

    Parasympatholytics

    Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)

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CO.,","customerCountry":"CHINA","quantity":"12.00","actualQuantity":"12","unit":"KGS","unitRateFc":"400","totalValueFC":"4653.4","currency":"USD","unitRateINR":32323.333333333332,"date":"16-May-2024","totalValueINR":"387880","totalValueInUsd":"4653.4","indian_port":"Hyderabad Air","hs_no":"29239000","bill_no":"9915386","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"PLOT 68,69, 2ND FLOOR, JUBILEE,HEI, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717525800,"product":"PINAVERIUM BROMIDE","address":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N","city":"HYDERABAD,TELANGANA","supplier":"AURORE LIFE SCIENCES","supplierCountry":"INDIA","foreign_port":"MEXICO CITY","customer":"MOLECULAS FINAS DE MEXICO SA DE C.V","customerCountry":"MEXICO","quantity":"2375.00","actualQuantity":"2375","unit":"KGS","unitRateFc":"150","totalValueFC":"335752.7","currency":"USD","unitRateINR":11801.448631578947,"date":"05-Jun-2024","totalValueINR":"28028440.5","totalValueInUsd":"335752.7","indian_port":"Hyderabad Air","hs_no":"29349990","bill_no":"1453538","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"MEXICO","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718735400,"product":"PINAVERIUM BROMIDE","address":"PLOT 68,69, 2ND FLOOR, JUBILEE,HEI","city":"HYDERABAD,TELANGANA","supplier":"AURORE PHARMACEUTICALS PRIVATE ","supplierCountry":"INDIA","foreign_port":"BOGOTA","customer":"RESEARCH PHARMACEUTICAL S.A","customerCountry":"COLOMBIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"194","totalValueFC":"4661.1","currency":"USD","unitRateINR":15564.4,"date":"19-Jun-2024","totalValueINR":"389110","totalValueInUsd":"4661.1","indian_port":"Hyderabad Air","hs_no":"29239000","bill_no":"1787629","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"COLOMBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"PLOT 68,69, 2ND FLOOR, JUBILEE,HEI, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718735400,"product":"PINAVERIUM BROMIDE","address":"PLOT 68,69, 2ND FLOOR, JUBILEE,HEI","city":"HYDERABAD,TELANGANA","supplier":"AURORE PHARMACEUTICALS PRIVATE ","supplierCountry":"INDIA","foreign_port":"BOGOTA","customer":"RESEARCH PHARMACEUTICAL S.A","customerCountry":"COLOMBIA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"194","totalValueFC":"37572.5","currency":"USD","unitRateINR":15682.65,"date":"19-Jun-2024","totalValueINR":"3136530","totalValueInUsd":"37572.5","indian_port":"Hyderabad Air","hs_no":"29239000","bill_no":"1787636","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"COLOMBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"PLOT 68,69, 2ND FLOOR, JUBILEE,HEI, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1719426600,"product":"PINAVERIUM BROMIDE, MFG. DATE:JUN-2023,JULY-2023, AUG-2023.NOV 2023 RETEST DATE:MAY-2027,JUN-2027,JUL-2027,OCT 2027","address":"PLOT NO.1-A SEC-16A","city":"NOIDA (U.P) INDIA","supplier":"JUBILANT PHARMOVA","supplierCountry":"INDIA","foreign_port":"SANTOS","customer":"TO THE ORDER OF","customerCountry":"BRAZIL","quantity":"5000.00","actualQuantity":"5000","unit":"KGS","unitRateFc":"156","totalValueFC":"765984.7","currency":"USD","unitRateINR":12788.792799999999,"date":"27-Jun-2024","totalValueINR":"63943964","totalValueInUsd":"765984.7","indian_port":"Bangalore ICD","hs_no":"29239000","bill_no":"1987751","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore ICD","supplierAddress":"PLOT NO.1-A SEC-16A, NOIDA (U.P) INDIA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724265000,"product":"PINAVERIUM BROMIDE","address":"PLOT 68,69, 2ND FLOOR, JUBILEE,HEI","city":"HYDERABAD,TELANGANA","supplier":"AURORE PHARMACEUTICALS PRIVATE ","supplierCountry":"INDIA","foreign_port":"SHANGHAI","customer":"ZHEJIANG LUYUAN PHARMACEUTICAL CO.,","customerCountry":"CHINA","quantity":"8.00","actualQuantity":"8","unit":"KGS","unitRateFc":"400","totalValueFC":"3067.8","currency":"USD","unitRateINR":32165,"date":"22-Aug-2024","totalValueINR":"257320","totalValueInUsd":"3067.8","indian_port":"Hyderabad Air","hs_no":"29239000","bill_no":"3388016","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"PLOT 68,69, 2ND FLOOR, JUBILEE,HEI, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725042600,"product":"PHARMACEUTICALS RAW MATERIAL BULK DRUGS PINAVERIUM BROMIDE (APBR III) IH","address":"20 C HAZRA ROAD","city":"KOLKATA","supplier":"ANZEN EXPORTS","supplierCountry":"INDIA","foreign_port":"BOGOTA","customer":"TO THE ORDER..,.,","customerCountry":"COLOMBIA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"212.2","totalValueFC":"39811","currency":"USD","unitRateINR":16696.452000000001,"date":"31-Aug-2024","totalValueINR":"3339290.4","totalValueInUsd":"39811","indian_port":"Bombay Air","hs_no":"29239000","bill_no":"3641390","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"COLOMBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"20 C HAZRA ROAD, KOLKATA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727029800,"product":"PINAVERIUM BROMIDEB\/NO: PBR2311048MFG DT: NOV-2023,RETEST DAT: OCT-2027","address":"PLOT NO.1-A SEC-16A","city":"NOIDA (U.P) INDIA","supplier":"JUBILANT PHARMOVA","supplierCountry":"INDIA","foreign_port":"BARRANQUILLA","customer":"LABORATORIOS INCOBRA S.A","customerCountry":"COLOMBIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"350","totalValueFC":"1631.3","currency":"USD","unitRateINR":27340.420000000002,"date":"23-Sep-2024","totalValueINR":"136702.1","totalValueInUsd":"1631.3","indian_port":"Bangalore Air","hs_no":"29239000","bill_no":"4254789","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"COLOMBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore Air","supplierAddress":"PLOT NO.1-A SEC-16A, NOIDA (U.P) INDIA","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1632076200,"product":"PINAVERIUM BROMIDE 25KG M2I FR","address":"UNIT NOS. 3&4, CORPORATE PARK,SION-TROMBAY ROAD, CHEMBUR,","city":"MUMBAI. MAHARASHTRA","supplier":"ABBOTT LABORATORIES","supplierCountry":"FRANCE","foreign_port":"#N\/A","customer":"ABBOTT LABORATORIES","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"136.4","totalValueFC":"3449.1","currency":"USD","unitRateINR":"10148.2","date":"20-Sep-2021","totalValueINR":"253704","totalValueInUsd":"3449.1","indian_port":"BOMBAY AIR","hs_no":"29349990","bill_no":"5508031","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"UNIT NOS. 3&4, CORPORATE PARK,SION-TROMBAY ROAD, CHEMBUR,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1699900200,"product":"(RE-IMPORT) PINAVERIUM BROMIDE","address":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N","city":"HYDERABAD,TELANGANA","supplier":"M\/S.MOLECULAS FINAS DE MEXICO SA DE CV","supplierCountry":"INDIA","foreign_port":"MANZANILLO","customer":"AURORE LIFE SCIENCES","customerCountry":"INDIA","quantity":"3100.00","actualQuantity":"3100","unit":"KGS","unitRateFc":"159","totalValueFC":"498103.7","currency":"USD","unitRateINR":"13379.9","date":"14-Nov-2023","totalValueINR":"41477535","totalValueInUsd":"498103.7","indian_port":"JNPT","hs_no":"29349990","bill_no":"8765406","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"MANZANILLO","supplierAddress":"CARRETERA TEXCOCO LECHERIA KM 23.5S\/N INT.BDGA 4 101,LA MAGDALENA PANOAYA TEXC OCO ESTADO DE MEXICO CP:5 MEXICO","customerAddress":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N"}]
    11-Feb-2021
    23-Sep-2024
    KGS
    overview
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    Europe

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    01

    Viatris Pharma GmbH

    U.S.A
    Fi Europe 2024
    Not Confirmed
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    Viatris Pharma GmbH

    U.S.A
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    Fi Europe 2024
    Not Confirmed
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    Regulatory Info :

    Registration Country : Switzerland

    Pinaverii bromide

    Brand Name : Dicetel

    Dosage Form : Film-Coated Tablets

    Dosage Strength : 50mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    02

    Viatris Pharma GmbH

    U.S.A
    Fi Europe 2024
    Not Confirmed
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    Viatris Pharma GmbH

    U.S.A
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    Fi Europe 2024
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
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    Regulatory Info :

    Registration Country : Switzerland

    Pinaverii bromide

    Brand Name : Dicetel

    Dosage Form : Film-Coated Tablets

    Dosage Strength : 50mg

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Switzerland

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    03

    SOLVAY PHARMA SpA

    Country
    Fi Europe 2024
    Not Confirmed
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    SOLVAY PHARMA SpA

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    Fi Europe 2024
    Not Confirmed
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    Regulatory Info :

    Registration Country : Italy

    Pinaverium

    Brand Name : Dicetel

    Dosage Form :

    Dosage Strength : 30 Cpr Riv 50 Mg  

    Packaging :

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Italy

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    Finished Drug Prices

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    01

    Brand Name : Dicetel

    U.S.A
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    BMWS24
    Not Confirmed

    Brand Name : Dicetel

    U.S.A
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    BMWS24
    Not Confirmed

    Viatris Pharma GmbH

    Pinaverium Bromide

    Dosage Form : Film-Coated Tablets

    Dosage Strength : 50mg

    Price Per Pack (Euro) : 9.39

    Published in :

    Country : Switzerland

    RX/OTC/DISCN : Class B

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    02

    Brand Name : Dicetel

    U.S.A
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    BMWS24
    Not Confirmed

    Brand Name : Dicetel

    U.S.A
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    BMWS24
    Not Confirmed

    Viatris Pharma GmbH

    Pinaverium Bromide

    Dosage Form : Film-Coated Tablets

    Dosage Strength : 50mg

    Price Per Pack (Euro) : 16.49

    Published in :

    Country : Switzerland

    RX/OTC/DISCN : Class B

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    Website

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    03

    Brand Name : Dicetel

    Country
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    BMWS24
    Not Confirmed

    Brand Name : Dicetel

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    BMWS24
    Not Confirmed

    SOLVAY PHARMA SpA

    Pinaverium Bromide

    Dosage Form :

    Dosage Strength : 30 Cpr Riv 50 Mg  

    Price Per Pack (Euro) : 12.04

    Published in :

    Country : Italy

    RX/OTC/DISCN : Class C

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