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1. Glycomul S
2. Sorbitan Stearate
3. Sorgen 50
4. 1338-41-6
5. Sorbitan Monosterate
6. Schembl285527
7. Sorbitan Monostearate Kosher P
8. Octadecanoic Acid [2-[(2r,3s,4r)-3,4-dihydroxy-2-tetrahydrofuranyl]-2-hydroxyethyl] Ester
Molecular Weight | 430.6 g/mol |
---|---|
Molecular Formula | C24H46O6 |
XLogP3 | 6.9 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 6 |
Rotatable Bond Count | 20 |
Exact Mass | 430.32943918 g/mol |
Monoisotopic Mass | 430.32943918 g/mol |
Topological Polar Surface Area | 96.2 Ų |
Heavy Atom Count | 30 |
Formal Charge | 0 |
Complexity | 417 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 3 |
Undefined Atom Stereocenter Count | 1 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
The formulation and characterization of a novel anhydrous organogel formulated as a potential delivery vehicle from a solution of 2 nonionic surfactants, sorbitan monostearate (Span 60) and polysorbate 20 (polyoxyethylene sorbitan monolaurate; Tween 20), in hexadecane at 60DGC, which cools to a white, semi-solid, thermoreversible gel at room temperature, are described. The addition of an aqueous phase (water or niosome suspensions) up to 17% v/v to the oil phase at 60DGC produced water-in-oil and vesicle-in-water-in-oil systems, respectively. The release rate of hydrophilic solute from these gels was found to be lowest when a disperse system of spherical water droplets in the continuous oil phase was formed at high temperatures, compared to the faster release from the gel where the fibril structures acted as nearly continuous aqueous channels running through the organic medium, providing a means of traversing the oil phase.
Murdan S et al; S.T.P. Pharma Sci 6 (1): 44-8 (1996)
1. 1= PRACTICALLY NON-TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) ABOVE 15 G/KG, MORE THAN 1 QT FOR 70 KG PERSON (150 LB).
Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. II-181
WHEN DIGESTED, BOTH THE FATTY ACID AND THE POLYHYDRIC ALCOHOL SORBITAN ARE ABSORBED, BUT THE LATTER IS COMPLETELY EXCRETED IN URINE.
Gosselin, R.E., H.C. Hodge, R.P. Smith, and M.N. Gleason. Clinical Toxicology of Commercial Products. 4th ed. Baltimore: Williams and Wilkins, 1976., p. II-181
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PharmaCompass offers a list of Glycomul S API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Glycomul S manufacturer or Glycomul S supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Glycomul S manufacturer or Glycomul S supplier.
PharmaCompass also assists you with knowing the Glycomul S API Price utilized in the formulation of products. Glycomul S API Price is not always fixed or binding as the Glycomul S Price is obtained through a variety of data sources. The Glycomul S Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Span 60 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Span 60, including repackagers and relabelers. The FDA regulates Span 60 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Span 60 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Span 60 manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Span 60 supplier is an individual or a company that provides Span 60 active pharmaceutical ingredient (API) or Span 60 finished formulations upon request. The Span 60 suppliers may include Span 60 API manufacturers, exporters, distributors and traders.
click here to find a list of Span 60 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Span 60 DMF (Drug Master File) is a document detailing the whole manufacturing process of Span 60 active pharmaceutical ingredient (API) in detail. Different forms of Span 60 DMFs exist exist since differing nations have different regulations, such as Span 60 USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Span 60 DMF submitted to regulatory agencies in the US is known as a USDMF. Span 60 USDMF includes data on Span 60's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Span 60 USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Span 60 suppliers with USDMF on PharmaCompass.
Span 60 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Span 60 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Span 60 GMP manufacturer or Span 60 GMP API supplier for your needs.
A Span 60 CoA (Certificate of Analysis) is a formal document that attests to Span 60's compliance with Span 60 specifications and serves as a tool for batch-level quality control.
Span 60 CoA mostly includes findings from lab analyses of a specific batch. For each Span 60 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Span 60 may be tested according to a variety of international standards, such as European Pharmacopoeia (Span 60 EP), Span 60 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Span 60 USP).