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ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 23312-56-3, Spectinomycin sulphate, Actinospectacin, Trobicin, Bz0h4tlf9x, Nsc100859
Molecular Formula
C14H26N2O11S
Molecular Weight
430.43  g/mol
InChI Key
XGBFWQUQYQIFLB-MTTMTQIXSA-N
FDA UNII
BZ0H4TLF9X

Spectinomycin Sulphate
An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
1 2D Structure

Spectinomycin Sulphate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sulfuric acid;(1R,3S,5R,8R,10R,11S,12S,13R,14S)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one
2.1.2 InChI
InChI=1S/C14H24N2O7.H2O4S/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;1-5(2,3)4/h5,7-13,15-16,18-20H,4H2,1-3H3;(H2,1,2,3,4)/t5-,7-,8+,9+,10+,11-,12-,13+,14+;/m1./s1
2.1.3 InChI Key
XGBFWQUQYQIFLB-MTTMTQIXSA-N
2.1.4 Canonical SMILES
CC1CC(=O)C2(C(O1)OC3C(C(C(C(C3O2)NC)O)NC)O)O.OS(=O)(=O)O
2.1.5 Isomeric SMILES
C[C@@H]1CC(=O)[C@]2([C@@H](O1)O[C@@H]3[C@H]([C@@H]([C@@H]([C@@H]([C@H]3O2)NC)O)NC)O)O.OS(=O)(=O)O
2.2 Other Identifiers
2.2.1 UNII
BZ0H4TLF9X
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Actinospectacin

2. Adspec

3. Ferkel Spectam

4. Kempi

5. Prospec

6. Salmosan T

7. Salmosan-t

8. Spectam

9. Spectam, Ferkel

10. Spectinomycin

11. Spectinomycin Dihydrochloride, Anhydrous

12. Spectinomycin Dihydrochloride, Pentahydrate

13. Spectinomycin Hydrochloride

14. Stanilo

15. Trobicin

2.3.2 Depositor-Supplied Synonyms

1. 23312-56-3

2. Spectinomycin Sulphate

3. Actinospectacin

4. Trobicin

5. Bz0h4tlf9x

6. Nsc100859

7. Xk 43-1

8. Sulfuric Acid;(1r,3s,5r,8r,10r,11s,12s,13r,14s)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one

9. U 18409

10. Unii-bz0h4tlf9x

11. Togamycin Sulfate (1:1)

12. Einecs 245-578-7

13. Mfcd00270185

14. Actinospectacin Sulfate

15. Schembl134977

16. Actinospectacin Sulphate

17. Chembl1969020

18. Dtxsid40945986

19. Yaa31256

20. Nsc-100859

21. Q-201733

22. Q27274974

23. (2r-(2.alpha.,4a.beta.,5a.beta.,6.beta.,7.beta.,8.beta.,9.alpha.,9a.alpha.,10a.beta.))-decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-4h-pyrano(2,3-b)(1,4)benzodioxin-4-one Sulfate

24. (2r-(2.alpha.,4a.beta.,5a.beta.,6.beta.,7.beta.,8.beta.,9.alpha.,9a.alpha.,10a.beta.))-decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-4h-pyrano(2,3-b)(1,4)benzodioxin-4-one Sulphate

25. 4h-pyrano(2,3-b)(1,4)benzodioxin-4-one, Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, (2r,4ar,5ar,6s,7s,8r,9s,9ar,10as)-, Sulfate (1:1)

26. 4h-pyrano(2,3-b)(1,4)benzodioxin-4-one, Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, (2r,4ar,5ar,6s,7s,8r,9s,9ar,10as)-, Sulphate (1:1)

27. 4h-pyrano(2,3-b)(1,4)benzodioxin-4-one, Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, Sulfate (1:1) (salt)

28. 4h-pyrano(2,3-b)(1,4)benzodioxin-4-one, Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, Sulphate (1:1) (salt)

29. 4h-pyrano[2,4]benzodioxin-4-one, Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, [2r-(2.alpha.,4a.beta.,5a.beta.,6.beta.,7.beta.,8.beta.,9.alpha.,9a.alpha.,10a.beta.)]-, Sulfate (1:1) (salt)

30. Sulfuric Acid--4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4h-pyrano[2,3-b][1,4]benzodioxin-4-one (1/1)

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 430.43 g/mol
Molecular Formula C14H26N2O11S
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count13
Rotatable Bond Count2
Exact Mass430.12573082 g/mol
Monoisotopic Mass430.12573082 g/mol
Topological Polar Surface Area213 Ų
Heavy Atom Count28
Formal Charge0
Complexity559
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


ABOUT THIS PAGE

Spectinomycin Sulphate Manufacturers

A Spectinomycin Sulphate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Spectinomycin Sulphate, including repackagers and relabelers. The FDA regulates Spectinomycin Sulphate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Spectinomycin Sulphate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Spectinomycin Sulphate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Spectinomycin Sulphate Suppliers

A Spectinomycin Sulphate supplier is an individual or a company that provides Spectinomycin Sulphate active pharmaceutical ingredient (API) or Spectinomycin Sulphate finished formulations upon request. The Spectinomycin Sulphate suppliers may include Spectinomycin Sulphate API manufacturers, exporters, distributors and traders.

click here to find a list of Spectinomycin Sulphate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Spectinomycin Sulphate CEP

A Spectinomycin Sulphate CEP of the European Pharmacopoeia monograph is often referred to as a Spectinomycin Sulphate Certificate of Suitability (COS). The purpose of a Spectinomycin Sulphate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Spectinomycin Sulphate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Spectinomycin Sulphate to their clients by showing that a Spectinomycin Sulphate CEP has been issued for it. The manufacturer submits a Spectinomycin Sulphate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Spectinomycin Sulphate CEP holder for the record. Additionally, the data presented in the Spectinomycin Sulphate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Spectinomycin Sulphate DMF.

A Spectinomycin Sulphate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Spectinomycin Sulphate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Spectinomycin Sulphate suppliers with CEP (COS) on PharmaCompass.

Spectinomycin Sulphate GMP

Spectinomycin Sulphate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Spectinomycin Sulphate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Spectinomycin Sulphate GMP manufacturer or Spectinomycin Sulphate GMP API supplier for your needs.

Spectinomycin Sulphate CoA

A Spectinomycin Sulphate CoA (Certificate of Analysis) is a formal document that attests to Spectinomycin Sulphate's compliance with Spectinomycin Sulphate specifications and serves as a tool for batch-level quality control.

Spectinomycin Sulphate CoA mostly includes findings from lab analyses of a specific batch. For each Spectinomycin Sulphate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Spectinomycin Sulphate may be tested according to a variety of international standards, such as European Pharmacopoeia (Spectinomycin Sulphate EP), Spectinomycin Sulphate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Spectinomycin Sulphate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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