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Chemistry

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Also known as: D-erythro-sphingosine, 123-78-4, 4-sphingenine, D-sphingosine, Sphing-4-enine, Sphingenine
Molecular Formula
C18H37NO2
Molecular Weight
299.5  g/mol
InChI Key
WWUZIQQURGPMPG-KRWOKUGFSA-N
FDA UNII
NGZ37HRE42

Sphingosine
An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
1 2D Structure

Sphingosine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(E,2S,3R)-2-aminooctadec-4-ene-1,3-diol
2.1.2 InChI
InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1
2.1.3 InChI Key
WWUZIQQURGPMPG-KRWOKUGFSA-N
2.1.4 Canonical SMILES
CCCCCCCCCCCCCC=CC(C(CO)N)O
2.1.5 Isomeric SMILES
CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)N)O
2.2 Other Identifiers
2.2.1 UNII
NGZ37HRE42
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4 Sphingenine

2. 4-sphingenine

2.3.2 Depositor-Supplied Synonyms

1. D-erythro-sphingosine

2. 123-78-4

3. 4-sphingenine

4. D-sphingosine

5. Sphing-4-enine

6. Sphingenine

7. 4-trans-sphingenine

8. (4e)-sphingenine

9. (2s,3r,4e)-2-amino-4-octadecene-1,3-diol

10. Trans-d-erythro-2-amino-4-octadecene-1,3-diol

11. D-erythro-sphingosine (synthetic)

12. Trans-4-sphingenine

13. Dl-erythro-sphingosine

14. Erythro-dl-sphingosine

15. Sphingoid

16. (e,2s,3r)-2-aminooctadec-4-ene-1,3-diol

17. C18-erythro-sphingenine

18. (2s,3r)-sphingosine

19. (2s,3r,4e)-2-aminooctadec-4-ene-1,3-diol

20. 4-octadecene-1,3-diol, 2-amino-, (2s,3r,4e)-

21. C18-sphingosine

22. D-erythro-c18-sphingosine

23. (-)-d-erythro-sphingosine

24. (-)-sphingosine

25. (e)-2-amino-4-octadecan-1,3-diol

26. Ccris 6899

27. Erythro-4-sphingenine

28. (2s,3r)-2-aminooctadec-4-ene-1,3-diol

29. (2s,3r,e)-2-aminooctadec-4-ene-1,3-diol

30. 2s-amino-4e-octadecene-1,3r-diol

31. Ngz37hre42

32. 0y6svq612q

33. 4-octadecene-1,3-diol, 2-amino-, (r-(r*,s*-(e)))-

34. Chebi:16393

35. 4-octadecene-1,3-diol, 2-amino-, (e)-dl-erythro-

36. 4-octadecene-1,3-diol, 2-amino-, (r*,s*-(e))-

37. 4-octadecene-1,3-diol, 2-amino-, (2r,3s,4e)-rel-

38. 2-aminooctadec-4-ene-1,3-diol

39. (2s,3r)-2-amino-4-octadecene-1,3-diol

40. Mls-0412588.0001

41. Sphingosin

42. (4e)-sphing-4-enine

43. Erythrosphingosine

44. Smr000857107

45. Erythro-c18-sphingosine

46. C18h37no2

47. 2733-29-1

48. Chembl67166

49. Mfcd00036751

50. Unii-ngz37hre42

51. 4-octadecene-1,3-diol, 2-amino-, [r-[r*,s*-(e)]]-

52. Unii-0y6svq612q

53. Derysphingosine

54. C18 Sphingosine

55. D-erythrosphingosine

56. Einecs 204-651-3

57. Sphingosine D18:1

58. D-erythro-spinghosine

59. (e)-d-erythro-4-octadecene-1,3-diol

60. D-sphingosine, Synthetic

61. Sphingosine, C18 Chain

62. Biomolki_000034

63. Sphingosine [mi]

64. Biomolki2_000042

65. Bmse000850

66. (2s,3r,e)-2-amino-4-octadecene-1,3-diol

67. Sphingosine With C18 Chain

68. Lopac0_001049

69. Schembl19398

70. Bspbio_001526

71. Mls001332469

72. Mls001332470

73. Mls002172450

74. D18:1 D-erythro-sphingosine

75. Bmk1-d10

76. Bml3-c09

77. Gtpl2452

78. Schembl1471985

79. Bdbm83205

80. Chebi:26743

81. Cid_5280335

82. Dtxsid90861763

83. 4-octadecene-1,3-diol, 2-amino-, (r*,s*-(e))-(+)-

84. Hms1361m08

85. Hms1791m08

86. Hms1989m08

87. Hms2232m04

88. Hms3402m08

89. Hms3650m05

90. D-(+)-erytho-4-trans-sphingenine

91. Dl-erythro-sphingosine [mi]

92. Ex-a1428

93. Zinc8195650

94. Ei-155

95. Lmsp01010001

96. S2210

97. D-sphingosine, >=98.0% (tlc)

98. Akos024458590

99. Ccg-100638

100. Db03203

101. Erythro-sphingosine, (+/-)-

102. Idi1_033996

103. Ncgc00024697-02

104. Ncgc00024697-03

105. Ncgc00024697-04

106. Ncgc00024697-05

107. Ncgc00024697-06

108. Ncgc00024697-07

109. Ac-28329

110. As-66175

111. Hy-101047

112. B6385

113. Cs-0020759

114. S0874

115. (e,2s,3r)-2-amino-4-octadecene-1,3-diol

116. (e,2s,3r)-2-azanyloctadec-4-ene-1,3-diol

117. C00319

118. F20671

119. Q46298

120. D-sphingosine, From Bovine Brain, ~99% (tlc)

121. A901185

122. Sr-01000597656

123. (2s,3r)-(e)-2-amino-1,3-dihydroxy-4-octadecene

124. (2s,3r,4e)-2-amino-3-hydroxyoctadec-4-ene-1-ol

125. J-004983

126. Sphingosine (d18:1), D-erythro-sphingosine, Powder

127. Sr-01000597656-1

128. [r-[r*,s*-(e)]]-2-amino-4-octadecene-1,3-diol

129. E66de871-3b37-406a-891b-a804bdc7abf9

130. 4-octadecene-1,3-diol, 2-amino-, (2s,3r,4e)- (9ci)

131. 4-octadecene-1,3-diol, 2-amino-, (e)-d-erythro-

132. 4-octadecene-1,3-diol, 2-amino-, (e)-d-erythro- (8ci)

133. 4-octadecene-1,3-diol, 2-amino-, (r-(r*,s*-(e)))

134. D-(+)-erythro-1,3-dihydroxy-2-amino-4-trans-octadecene

135. 4-octadecene-1,3-diol, 2-amino-, (r*,s*-(e))-(+/-)-

136. Brain Sphingosine, D-erythro-sphingosine (brain, Porcine), Powder

137. 89164-20-5

138. Sqs

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 299.5 g/mol
Molecular Formula C18H37NO2
XLogP35.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count15
Exact Mass299.282429423 g/mol
Monoisotopic Mass299.282429423 g/mol
Topological Polar Surface Area66.5 Ų
Heavy Atom Count21
Formal Charge0
Complexity231
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API Reference Price

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26-Oct-2023
28-Jun-2024
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ABOUT THIS PAGE

Sphingosine Manufacturers

A Sphingosine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sphingosine, including repackagers and relabelers. The FDA regulates Sphingosine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sphingosine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sphingosine Suppliers

A Sphingosine supplier is an individual or a company that provides Sphingosine active pharmaceutical ingredient (API) or Sphingosine finished formulations upon request. The Sphingosine suppliers may include Sphingosine API manufacturers, exporters, distributors and traders.

click here to find a list of Sphingosine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sphingosine USDMF

A Sphingosine DMF (Drug Master File) is a document detailing the whole manufacturing process of Sphingosine active pharmaceutical ingredient (API) in detail. Different forms of Sphingosine DMFs exist exist since differing nations have different regulations, such as Sphingosine USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Sphingosine DMF submitted to regulatory agencies in the US is known as a USDMF. Sphingosine USDMF includes data on Sphingosine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Sphingosine USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Sphingosine suppliers with USDMF on PharmaCompass.

Sphingosine GMP

Sphingosine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sphingosine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sphingosine GMP manufacturer or Sphingosine GMP API supplier for your needs.

Sphingosine CoA

A Sphingosine CoA (Certificate of Analysis) is a formal document that attests to Sphingosine's compliance with Sphingosine specifications and serves as a tool for batch-level quality control.

Sphingosine CoA mostly includes findings from lab analyses of a specific batch. For each Sphingosine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sphingosine may be tested according to a variety of international standards, such as European Pharmacopoeia (Sphingosine EP), Sphingosine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sphingosine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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