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Chemistry

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Also known as: Spicamycin analog, Nsc650426, 151276-95-8, Krn5500, (2e,4e)-n-[2-[[(2r,3r,4r,5r,6s)-2-[(1s)-1,2-dihydroxyethyl]-4,5-dihydroxy-6-(7h-purin-6-ylamino)oxan-3-yl]amino]-2-oxoethyl]tetradeca-2,4-dienamide, Nsc-650426
Molecular Formula
C28H43N7O7
Molecular Weight
589.7  g/mol
InChI Key
LQIPDFIUPOYMPR-AQASXUMVSA-N

Spicamycin Analog
1 2D Structure

Spicamycin Analog

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2E,4E)-N-[2-[[2-(1,2-dihydroxyethyl)-4,5-dihydroxy-6-(7H-purin-6-ylamino)oxan-3-yl]amino]-2-oxoethyl]tetradeca-2,4-dienamide
2.1.2 InChI
InChI=1S/C28H43N7O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-19(38)29-14-20(39)34-21-23(40)24(41)28(42-25(21)18(37)15-36)35-27-22-26(31-16-30-22)32-17-33-27/h10-13,16-18,21,23-25,28,36-37,40-41H,2-9,14-15H2,1H3,(H,29,38)(H,34,39)(H2,30,31,32,33,35)/b11-10+,13-12+
2.1.3 InChI Key
LQIPDFIUPOYMPR-AQASXUMVSA-N
2.1.4 Canonical SMILES
CCCCCCCCCC=CC=CC(=O)NCC(=O)NC1C(C(C(OC1C(CO)O)NC2=NC=NC3=C2NC=N3)O)O
2.1.5 Isomeric SMILES
CCCCCCCCC/C=C/C=C/C(=O)NCC(=O)NC1C(C(C(OC1C(CO)O)NC2=NC=NC3=C2NC=N3)O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 6-(4-deoxy-4-((2e,4e)-tetradecadienoylglycyl)amino-l-glycero-b-l-mannoheptopyranosyl)amino-9h-purine

2. Krn 5500

3. Krn-5500

4. Krn5500

2.2.2 Depositor-Supplied Synonyms

1. Spicamycin Analog

2. Nsc650426

3. 151276-95-8

4. Krn5500

5. (2e,4e)-n-[2-[[(2r,3r,4r,5r,6s)-2-[(1s)-1,2-dihydroxyethyl]-4,5-dihydroxy-6-(7h-purin-6-ylamino)oxan-3-yl]amino]-2-oxoethyl]tetradeca-2,4-dienamide

6. Nsc-650426

7. Schembl1650068

8. Chembl1988585

9. (2e,4e)-n-[2-[[(2r,3r,4r,5r,6s)-2-(1,2-dihydroxyethyl)-4,5-dihydroxy-6-(7h-purin-6-ylamino)oxan-3-yl]amino]-2-oxoethyl]tetradeca-2,4-dienamide

10. 4-deoxy-n-(7h-purin-6-yl)-4-(((2,4-tetradecadienoylamino)acetyl)amino)heptopyranosylamine

11. (2e,4e)-n-[2-[[2-(1,2-dihydroxyethyl)-4,5-dihydroxy-6-(7h-purin-6-ylamino)tetrahydropyran-3-yl]amino]-2-oxo-ethyl]tetradeca-2,4-dienamide

12. 6-[4-deoxy-4-(tetradeca-2(e), 4(e)-dienoylglycyl)amino-l-glycero-.beta.-l-manno-hepto-pyranosyl]amino-9h-purine

2.3 Create Date
2005-09-10
3 Chemical and Physical Properties
Molecular Weight 589.7 g/mol
Molecular Formula C28H43N7O7
XLogP32.7
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count11
Rotatable Bond Count17
Exact Mass589.32239674 g/mol
Monoisotopic Mass589.32239674 g/mol
Topological Polar Surface Area215 Ų
Heavy Atom Count42
Formal Charge0
Complexity880
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count6
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antineoplastic Agents

Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)


Protein Synthesis Inhibitors

Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins. (See all compounds classified as Protein Synthesis Inhibitors.)


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Looking for 151276-95-8 / Spicamycin Analog API manufacturers, exporters & distributors?

Spicamycin Analog manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Spicamycin Analog API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Spicamycin Analog manufacturer or Spicamycin Analog supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Spicamycin Analog manufacturer or Spicamycin Analog supplier.

PharmaCompass also assists you with knowing the Spicamycin Analog API Price utilized in the formulation of products. Spicamycin Analog API Price is not always fixed or binding as the Spicamycin Analog Price is obtained through a variety of data sources. The Spicamycin Analog Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Spicamycin Analog

Synonyms

Nsc650426, 151276-95-8, Krn5500, (2e,4e)-n-[2-[[(2r,3r,4r,5r,6s)-2-[(1s)-1,2-dihydroxyethyl]-4,5-dihydroxy-6-(7h-purin-6-ylamino)oxan-3-yl]amino]-2-oxoethyl]tetradeca-2,4-dienamide, Nsc-650426, Schembl1650068

Cas Number

151276-95-8

Spicamycin Analog Manufacturers

A Spicamycin Analog manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Spicamycin Analog, including repackagers and relabelers. The FDA regulates Spicamycin Analog manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Spicamycin Analog API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Spicamycin Analog Suppliers

A Spicamycin Analog supplier is an individual or a company that provides Spicamycin Analog active pharmaceutical ingredient (API) or Spicamycin Analog finished formulations upon request. The Spicamycin Analog suppliers may include Spicamycin Analog API manufacturers, exporters, distributors and traders.

click here to find a list of Spicamycin Analog suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Spicamycin Analog USDMF

A Spicamycin Analog DMF (Drug Master File) is a document detailing the whole manufacturing process of Spicamycin Analog active pharmaceutical ingredient (API) in detail. Different forms of Spicamycin Analog DMFs exist exist since differing nations have different regulations, such as Spicamycin Analog USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Spicamycin Analog DMF submitted to regulatory agencies in the US is known as a USDMF. Spicamycin Analog USDMF includes data on Spicamycin Analog's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Spicamycin Analog USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Spicamycin Analog suppliers with USDMF on PharmaCompass.

Spicamycin Analog GMP

Spicamycin Analog Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Spicamycin Analog GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Spicamycin Analog GMP manufacturer or Spicamycin Analog GMP API supplier for your needs.

Spicamycin Analog CoA

A Spicamycin Analog CoA (Certificate of Analysis) is a formal document that attests to Spicamycin Analog's compliance with Spicamycin Analog specifications and serves as a tool for batch-level quality control.

Spicamycin Analog CoA mostly includes findings from lab analyses of a specific batch. For each Spicamycin Analog CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Spicamycin Analog may be tested according to a variety of international standards, such as European Pharmacopoeia (Spicamycin Analog EP), Spicamycin Analog JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Spicamycin Analog USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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