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Synopsis

ACTIVE PHARMA INGREDIENTS

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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FDF

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Canada

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Australia

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1 RELATED EXCIPIENT COMPANIES

1EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Super squalene; trans-squalene;addavax, 7683-64-9, Squalen, Chembl3561564, Dtxsid4064767, Akos025243731
Molecular Formula
C30H50
Molecular Weight
410.7  g/mol
InChI Key
YYGNTYWPHWGJRM-UHFFFAOYSA-N

Squalene API
2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene is a natural product found in Ficus septica, Garcinia multiflora, and other organisms with data available.
1 2D Structure

Squalene API

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene
2.1.2 InChI
InChI=1S/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3
2.1.3 InChI Key
YYGNTYWPHWGJRM-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(=CCCC(=CCCC(=CCCC=C(C)CCC=C(C)CCC=C(C)C)C)C)C
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. Super Squalene; Trans-squalene;addavax

2. 7683-64-9

3. Squalen

4. Chembl3561564

5. Dtxsid4064767

6. Akos025243731

7. Ncgc00181323-02

8. Ft-0772415

2.3 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 410.7 g/mol
Molecular Formula C30H50
XLogP311.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count0
Rotatable Bond Count15
Exact Mass410.391251595 g/mol
Monoisotopic Mass410.391251595 g/mol
Topological Polar Surface Area0 Ų
Heavy Atom Count30
Formal Charge0
Complexity578
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count4
Covalently Bonded Unit Count1

API SUPPLIERS

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01

BioCatSyn (Shanghai) Biotechnology

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo
Not Confirmed
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BioCatSyn (Shanghai) Biotechnology

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
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CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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02

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USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo
Not Confirmed
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USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
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USDMF Inactive-api CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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03

SAFC

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo
Not Confirmed
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SAFC

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
Not Confirmed
USDMF Inactive-api CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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04

Matrix Life Science

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo
Not Confirmed
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05

Dishman Carbogen Amcis

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo
Not Confirmed
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Dishman Carbogen Amcis

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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06

Conscientia Industrial

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo
Not Confirmed
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Conscientia Industrial

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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USDMF

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01

Pharma, Lab & Chemical Expo
Not Confirmed

01

Pharma, Lab & Chemical Expo
Not Confirmed

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 38189

Submission : 2023-03-28

Status : Active

Type : IV

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02

Pharma, Lab & Chemical Expo
Not Confirmed

02

Pharma, Lab & Chemical Expo
Not Confirmed

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 12515

Submission : 1997-05-23

Status : Inactive

Type : II

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03

Robeco Chemicals Inc

Country

USDMF

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Pharma, Lab & Chemical Expo
Not Confirmed

03

Robeco Chemicals Inc

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Not Confirmed

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 2988

Submission : 1977-07-25

Status : Inactive

Type : II

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Listed Suppliers

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01

Pharma, Lab & Chemical Expo
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Squalene API

About the Company : Conscientia Industrial is a pharmaceutical company, mainly developing, manufacturing, marketing APIs (Active Pharmaceutical Ingredients), intermediates, fine chemicals in China. We...

Conscientia Industrial is a pharmaceutical company, mainly developing, manufacturing, marketing APIs (Active Pharmaceutical Ingredients), intermediates, fine chemicals in China. We started business in early 2010, producing and providing products for both human and veterinary health at home and abroad. Conscientia Industrial makes regular productions and also provides custom synthesis, contract manufacturing services. We have series of products, such as Hormones, Prostaglandins, Peptides, Anti-cancer, Anti-tumor, Anti-virus, Anti-diabetic APIs and their related intermediates, impurities, chemicals.
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02

Pharma, Lab & Chemical Expo
Not Confirmed
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Squalene

About the Company : We have been supporting the pharmaceutical and biopharmaceutical industries with drug development for over 30 years, assisting our clients in developing and bringing new drugs to m...

We have been supporting the pharmaceutical and biopharmaceutical industries with drug development for over 30 years, assisting our clients in developing and bringing new drugs to market while improving the lives of their patients across the world. Our objective is to help our customers create a better world as the partner of choice to develop and manufacture complex and challenging substances, highly potent active ingredients, and breaking new ground with innovative vitamin, healthcare, and industrial products.
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03

Pharma, Lab & Chemical Expo
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Squalene

About the Company : Leading Global Manufacturer and Supplier of Natural Ingredients like Tocopherols (Vitamin E), Rosemary Extracts & Phytosterols from a 100% Non- GMO sources. We are the first Ind...

Leading Global Manufacturer and Supplier of Natural Ingredients like Tocopherols (Vitamin E), Rosemary Extracts & Phytosterols from a 100% Non- GMO sources. We are the first Indian Company to manufacture Non-GMO natural mixed tocopherols, d-Alpha tocopherol and Phytosterols in high concentrations. With the largest installation capacities spanning over 80000 sq. meters. we are one of the few companies to provide the range of natural vitamin E along with its derivatives, Rosemary extracts and phytosterols under one roof.
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API Reference Price

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A6, VEERA, INDUSTRIAL ESTATE, OFF VEERA DESAI"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1642357800,"product":"SQUALENE (MARINE) 16 MS DRUMS( EACH CONTAINING 170 KG SQUALENE)","address":"DOOR NO.130 MOOPPIL HOUSE,MANAGTTIRI,TALAKKAD C","city":"TIRUR","supplier":"M\/S.MSS BIOCHEM FZ - LLC,","supplierCountry":"UNITED ARAB EMIRATES","foreign_port":"#N\/A","customer":"AMBITN LIFESCIENCES","customerCountry":"INDIA","quantity":"2720.00","actualQuantity":"2720","unit":"KGS","unitRateFc":"14","totalValueFC":"38543.4","currency":"USD","unitRateINR":"1055.6","date":"17-Jan-2022","totalValueINR":"2871232","totalValueInUsd":"38543.4","indian_port":"COCHIN SEA","hs_no":"29012990","bill_no":"7110734","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"UNITED ARAB EMIRATES","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"DOOR NO.130 MOOPPIL HOUSE,MANAGTTIRI,TALAKKAD C"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1654281000,"product":"SQUALENE (MIN 97%) CAS NO.111-02-04","address":"29\/314,KPK BUILDING, NUT STREET BADAGARA","city":"KOZHIKODE, KERALA","supplier":"MASS BIOCHEM FZ-LLC","supplierCountry":"UNITED ARAB EMIRATES","foreign_port":"NA","customer":"AASHA BIOCHEM","customerCountry":"INDIA","quantity":"4760.00","actualQuantity":"4760","unit":"KGS","unitRateFc":"13.5","totalValueFC":"64659.2","currency":"USD","unitRateINR":"1059.8","date":"04-Jun-2022","totalValueINR":"5044410","totalValueInUsd":"64659.2","indian_port":"MANGALORE SEA","hs_no":"29012990","bill_no":"8971353","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"UNITED ARAB EMIRATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"29\/314,KPK BUILDING, NUT STREET BADAGARA"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1670610600,"product":"OLIVE SQUALENE (FOR COSMETICS PREPARATION)","address":"401, 4TH FLOOR, JAGDAMBA HOUSE,PER U BAUG, GOREGAON EAST","city":"MUMBAI,MAHARASHTRA","supplier":"EMPRESA FIGUEIRENSE DE ","supplierCountry":"SPAIN","foreign_port":"NA","customer":"ANSHUL LIFE SCIENCES","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"18.3","totalValueFC":"808.8","currency":"EUR","unitRateINR":"2666","date":"10-Dec-2022","totalValueINR":"66649.77","totalValueInUsd":"808.8","indian_port":"BOMBAY AIR","hs_no":"29011000","bill_no":"3682748","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"401, 4TH FLOOR, JAGDAMBA HOUSE,PER U BAUG, GOREGAON EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1672252200,"product":"SQUALENE CAS NO. 111-02-04","address":"29\/314,KPK BUILDING, NUT STREET BADAGARA","city":"KOZHIKODE, KERALA","supplier":"MASS BIOCHEM FZ-LLC","supplierCountry":"UNITED ARAB EMIRATES","foreign_port":"NA","customer":"AASHA BIOCHEM","customerCountry":"INDIA","quantity":"5440.00","actualQuantity":"5440","unit":"KGS","unitRateFc":"13.5","totalValueFC":"74459.3","currency":"USD","unitRateINR":"1127.9","date":"29-Dec-2022","totalValueINR":"6135912","totalValueInUsd":"74459.3","indian_port":"MANGALORE SEA","hs_no":"29012990","bill_no":"3950398","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"UNITED ARAB EMIRATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"29\/314,KPK BUILDING, NUT STREET BADAGARA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1674153000,"product":"FERMENTATION DERIVED SQUALENE (INTERMEDIATE SUBSTANCE FOR DEVELOPMENT PURPOSE ONLY)","address":"B-1, EXTN, G-3, MOHAN CO-OPERATIVE INDUSTRIAL ESTATE, MATHURA ROAD","city":"NEW DELHI","supplier":"M\/S. AMYRIS INC.","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"PANACEA BIOTEC LIMITED","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"10","totalValueFC":"10.1","currency":"USD","unitRateINR":"823","date":"20-Jan-2023","totalValueINR":"823","totalValueInUsd":"10.1","indian_port":"DELHI AIR","hs_no":"29012990","bill_no":"4275181","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"B-1, EXTN, G-3, MOHAN CO-OPERATIVE INDUSTRIAL ESTATE, MATHURA ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1684175400,"product":"SOPHIDERM USP SQUALENE","address":"D 401 SATYADEV PLOT NO A6 VEERA INDUSTRIAL ESTATE OFF VEERA DESAI ROAD ANDHERI WEST MAHARASHT","city":"MUMBAI","supplier":"SOPHIM","supplierCountry":"FRANCE","foreign_port":"ANTWERPEN","customer":"YASHAM SPECIALITY INGREDIENTS ","customerCountry":"INDIA","quantity":"125.00","actualQuantity":"125","unit":"KGS","unitRateFc":"31.1","totalValueFC":"4542.7","currency":"EUR","unitRateINR":"2990.4","date":"16-May-2023","totalValueINR":"373796.37","totalValueInUsd":"4542.7","indian_port":"JNPT","hs_no":"29011000","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"France","selfForZScoreResived":"Pharma Grade","supplierPort":"ANTWERPEN","supplierAddress":"","customerAddress":"D 401 SATYADEV PLOT NO A6 VEERA INDUSTRIAL ESTATE OFF VEERA DESAI ROAD ANDHERI WEST MAHARASHT"}]
22-May-2021
11-Jan-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

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Drugs in Development

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Details:

Under the terms of the agreement, CSL Seqirus will deliver an H5N8 A/Astrakhan virus vaccine candidate and will then sponsor a subsequent Phase 2 clinical trial to evaluate the candidate along with CSL Seqirus' proprietary adjuvant MF59®.


Lead Product(s): H5N8 A/Astrakhan Virus Vaccine,Squalene API

Therapeutic Area: Infections and Infectious Diseases Brand Name: H5N8 A/Astrakhan

Study Phase: PreclinicalProduct Type: Vaccine

Sponsor: BARDA

Deal Size: $30.1 million Upfront Cash: Undisclosed

Deal Type: Agreement October 06, 2022

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01

Seqirus

Australia
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Pharma, Lab & Chemical Expo
Not Confirmed

Seqirus

Australia
arrow
Pharma, Lab & Chemical Expo
Not Confirmed

Details : Under the terms of the agreement, CSL Seqirus will deliver an H5N8 A/Astrakhan virus vaccine candidate and will then sponsor a subsequent Phase 2 clinical trial to evaluate the candidate along with CSL Seqirus' proprietary adjuvant MF59®.

Brand Name : H5N8 A/Astrakhan

Molecule Type : Vaccine

Upfront Cash : Undisclosed

October 06, 2022

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  • Deals

Details:

CSL said it will provide technical expertise and a donation of MF59 to the University of Queensland’s preclinical development program.


Lead Product(s): Squalene API

Therapeutic Area: Infections and Infectious Diseases Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Small molecule

Sponsor: University of Queensland

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration February 12, 2020

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02

CSL

Australia
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Pharma, Lab & Chemical Expo
Not Confirmed

CSL

Australia
arrow
Pharma, Lab & Chemical Expo
Not Confirmed

Details : CSL said it will provide technical expertise and a donation of MF59 to the University of Queensland’s preclinical development program.

Brand Name : Undisclosed

Molecule Type : Small molecule

Upfront Cash : Undisclosed

February 12, 2020

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ABOUT THIS PAGE

Squalene API Manufacturers

A Squalene API manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Squalene API, including repackagers and relabelers. The FDA regulates Squalene API manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Squalene API API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Squalene API manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Squalene API Suppliers

A Squalene API supplier is an individual or a company that provides Squalene API active pharmaceutical ingredient (API) or Squalene API finished formulations upon request. The Squalene API suppliers may include Squalene API API manufacturers, exporters, distributors and traders.

click here to find a list of Squalene API suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Squalene API USDMF

A Squalene API DMF (Drug Master File) is a document detailing the whole manufacturing process of Squalene API active pharmaceutical ingredient (API) in detail. Different forms of Squalene API DMFs exist exist since differing nations have different regulations, such as Squalene API USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Squalene API DMF submitted to regulatory agencies in the US is known as a USDMF. Squalene API USDMF includes data on Squalene API's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Squalene API USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Squalene API suppliers with USDMF on PharmaCompass.

Squalene API GMP

Squalene API Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Squalene API GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Squalene API GMP manufacturer or Squalene API GMP API supplier for your needs.

Squalene API CoA

A Squalene API CoA (Certificate of Analysis) is a formal document that attests to Squalene API's compliance with Squalene API specifications and serves as a tool for batch-level quality control.

Squalene API CoA mostly includes findings from lab analyses of a specific batch. For each Squalene API CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Squalene API may be tested according to a variety of international standards, such as European Pharmacopoeia (Squalene API EP), Squalene API JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Squalene API USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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