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Chemistry

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Also known as: 2418-14-6, Dimercaptosuccinic acid, 2,3-bis(sulfanyl)butanedioic acid, Suximer, 2,3-dimercaptobutanedioic acid, Butanedioic acid, 2,3-dimercapto-
Molecular Formula
C4H6O4S2
Molecular Weight
182.2  g/mol
InChI Key
ACTRVOBWPAIOHC-UHFFFAOYSA-N

Succimer
A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
1 2D Structure

Succimer

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2,3-bis(sulfanyl)butanedioic acid
2.1.2 InChI
InChI=1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8)
2.1.3 InChI Key
ACTRVOBWPAIOHC-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C(C(C(=O)O)S)(C(=O)O)S
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 2,3 Dimercaptosuccinic Acid

2. Acid, 2,3-dimercaptosuccinic

3. Acid, Dimercaptosuccinic

4. Acid, Meso-dimercaptosuccinic

5. Butanedioic Acid, 2,3-dimercapto-, (r*,s*)-isomer

6. Chemet

7. Dimercaptosuccinate, Tin

8. Dimercaptosuccinic Acid

9. Dipotassium Salt Succimer

10. Disodium Salt Succimer

11. Dmsa

12. Meso Dimercaptosuccinic Acid

13. Meso-dimercaptosuccinic Acid

14. Monosodium Salt Succimer

15. Rhenium Salt Succimer

16. Ro 1 7977

17. Ro-1-7977

18. Ro17977

19. Succicaptal

20. Succimer

21. Succimer Antimony Sodium Salt, (r*,s*)-isomer

22. Succimer, (r*,r*)-(+,-)-isomer

23. Succimer, Dipotassium Salt

24. Succimer, Disodium Salt

25. Succimer, Monosodium Salt

26. Succimer, Rhenium Salt

27. Succimer, Tin Salt

28. Tin Dimercaptosuccinate

29. Tin Salt Succimer

2.2.2 Depositor-Supplied Synonyms

1. 2418-14-6

2. Dimercaptosuccinic Acid

3. 2,3-bis(sulfanyl)butanedioic Acid

4. Suximer

5. 2,3-dimercaptobutanedioic Acid

6. Butanedioic Acid, 2,3-dimercapto-

7. Dimercaptosuccinicacid

8. Dmsa

9. 2,2-dimercaptosuccinic Acid

10. Dimercaptosuccinic Acid;dmsa

11. Mls001076671

12. Smr000499575

13. Dimercatposuccinic Acid

14. Nsc16866

15. Succinic Acid, 2,3-dimercapto-

16. 3-03-00-01033 (beilstein Handbook Reference)

17. Einecs 219-334-5

18. Nsc 259951

19. Brn 1725149

20. Unii-4s9ju7xf01

21. 2,3-dimercapto-succinic Acid

22. Imercaptosuccinic Acid

23. Cid_9354

24. 2,3-disulfanylsuccinic Acid

25. Succinic Acid,3-dimercapto-

26. Schembl14942

27. Mls001332563

28. Mls001332564

29. Chembl28721

30. Meso-2,3-dithiosuccinic Acid

31. 2,3-disulfanylbutanedioic Acid

32. Butanedioic Acid,3-dimercapto-

33. 2,3-disulfanylsuccinic Acid #

34. 4s9ju7xf01

35. Bdbm60868

36. Dtxsid10859324

37. Meso 2,3-dimercaptosuccinic Acid

38. Nsc259951

39. Mpi Dmsa Kidney Reagent (salt/mix)

40. Akos006228463

41. .alpha.,.beta.-dimercaptosuccinic Acid

42. Db14089

43. Nsc-259951

44. Ls-12987

45. Nci60_001347

46. A4995

47. Ft-0628241

48. Ft-0695306

49. 18d146

50. Q56604713

2.3 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 182.2 g/mol
Molecular Formula C4H6O4S2
XLogP30.1
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass181.97075102 g/mol
Monoisotopic Mass181.97075102 g/mol
Topological Polar Surface Area76.6 Ų
Heavy Atom Count10
Formal Charge0
Complexity139
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameMpi dmsa kidney reagent
Active IngredientTechnetium tc-99m succimer kit
Dosage FormInjectable
RouteInjection
Strengthn/a
Market StatusPrescription
CompanyGe Healthcare

2 of 2  
Drug NameMpi dmsa kidney reagent
Active IngredientTechnetium tc-99m succimer kit
Dosage FormInjectable
RouteInjection
Strengthn/a
Market StatusPrescription
CompanyGe Healthcare

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Antidotes

Agents counteracting or neutralizing the action of POISONS. (See all compounds classified as Antidotes.)


Chelating Agents

Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)


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05-Jan-2021
23-Jan-2023
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