Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

3 API Suppliers, 1 USDMF, 1 NDC API, 3 Listed Suppliers

3 API Suppliers
1 USDMF
1 NDC API
3 Listed Suppliers

FINISHED DOSAGE FORMULATIONS

2 FDF Dossiers, 2 FDA Orange Book

2 FDF Dossiers
2 FDA Orange Book

DRUG PRODUCT COMPOSITIONS

CREAM;TOPICAL - 1%, SOLUTION;TOPICAL - 1%

drugProductComposition
CREAM;TOPICAL - 1%
SOLUTION;TOPICAL - 1%

RELATED EXCIPIENT COMPANIES

5 Nanjing Well Pharmaceutical, 10 BASF, 1 Finar, 3 Gangwal Chemicals, 5 Kerry, 1 Microlex e.U, 1 Nanjing Bold Chemical, 4 Seppic, 1 Valens Pharmachem

relatedExcipients
5 Nanjing Well Pharmaceutical
10 BASF
1 Finar
3 Gangwal Chemicals
5 Kerry
1 Microlex e.U
1 Nanjing Bold Chemical
4 Seppic
1 Valens Pharmachem

EXCIPIENTS BY APPLICATIONS

15 Solubilizers, 15 Topical, 7 Emulsifying Agents, 7 Thickeners and Stabilizers, 6 Surfactant & Foaming Agents, 5 Co-Processed Excipients, 4 Parenteral, 2 Granulation, 2 Direct Compression, 2 Film Formers & Plasticizers, 2 Lubricants & Glidants, 1 Chewable & Orodispersible Aids, 1 Coating Systems & Additives

excipientsByApplications
15 Solubilizers
15 Topical
7 Emulsifying Agents
7 Thickeners and Stabilizers
6 Surfactant & Foaming Agents
5 Co-Processed Excipients
4 Parenteral
2 Granulation
2 Direct Compression
2 Film Formers & Plasticizers
2 Lubricants & Glidants
1 Chewable & Orodispersible Aids
1 Coating Systems & Additives

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow

media
1 DATA COMPILATION #PharmaFlow

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 1 Finished Drug Prices

globalSalesInformation
1 US Medicaid Prescriptions
1 Finished Drug Prices

REF. STANDARDS & IMPURITIES

1 USP , 1 Others

otherSolutions
1 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

49,018

Annual Reports (USD Million)

Finished Drug Prices

31 RELATED EXCIPIENT COMPANIES

69EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 61318-91-0, Exelderm, 82382-23-8, Sulconazole nitrate salt, 1-[2-(4-chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl]-1h-imidazole nitrate, Sulconazolenitrate

Molecular Formula

C₁₈H₁₆Cl₃N₃O₃S

Molecular Weight

460.8 g/mol

InChI Key

CRKGMGQUHDNAPB-UHFFFAOYSA-N

FDA UNII

1T89100D5U

Sulconazole Nitrate is the nitrate salt form of sulconazole, a synthetic imidazole derivative with antifungal property. Sulconazole nitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols and inhibition of the synthesis of ergosterol, an important component of the fungal cell membrane. Inhibition of ergosterol synthesis leads to a disruption of cell membrane permeability, and ultimately inhibition of cell wall synthesis. In addition, sulconazole nitrate seems to interfere with the autolytic degradation of fungal DNA and RNA.

1 2D Structure

Sulconazole Nitrate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-[2-[(4-chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid

2.1.2 InChI

InChI=1S/C18H15Cl3N2S.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)

2.1.3 InChI Key

CRKGMGQUHDNAPB-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1=CC(=CC=C1CSC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]

2.2 Other Identifiers

2.2.1 UNII

1T89100D5U

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 1-(beta-(4''-chlorobenzylthio)-2'4'-dichlorophenethyl)imidazole

2. Exelderm

3. Myk

4. Sulconazole

5. Sulconazole Mononitrate

6. Sulconazole, Mononitrate, (+-)-isomer

2.3.2 Depositor-Supplied Synonyms

1. 61318-91-0

2. Exelderm

3. 82382-23-8

4. Sulconazole Nitrate Salt

5. 1-[2-(4-chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl]-1h-imidazole Nitrate

6. Sulconazolenitrate

7. Sulconazole (mononitrate)

8. Sulcosyn

9. Rs 44872

10. Rs-44872

11. Sulconazole (nitrate)

12. 1-(2-((4-chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1h-imidazole Nitrate

13. Nsc-757849

14. Rs-44872-00-10-3

15. 1-[2-[(4-chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric Acid

16. Mls000028611

17. (+/-)-sulconazole (nitrate)

18. (+/-)-sulconazole (mononitrate)

19. 1-(2-[p-chlorobenzylthio]-2-[2,4-dichlorophenyl]ethyl)-1h-imidazole

20. Sulconazole Mononitrate

21. 1t89100d5u

22. 61318-91-0 (nitrate)

23. Smr000058734

24. Dsstox_cid_25490

25. Dsstox_rid_80911

26. Dsstox_gsid_45490

27. Sulconazle Nitrate

28. Sr-01000000237

29. Unii-1t89100d5u

30. 1-(2-(4-chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl)-1h-imidazole Nitrate

31. Exelderm (tn)

32. Prestwick_128

33. Mfcd00058163

34. Sulconazole Nitrate [usan:usp:jan]

35. Opera_id_1591

36. Ncgc00016898-01

37. (+-)-1-(2,4-dichloro-beta-((4-chlorobenzyl)thio)phenethyl)imidazole Nitrate

38. Sulconazole Nitrate (1:x)

39. Sulconazolenitratesalt

40. Cas-61318-91-0

41. (+-)-1-(2,4-dichloro-beta-((p-chlorobenzyl)thio)phenethyl)imidazole Mononitrate

42. Schembl36906

43. Mls001146948

44. Mls002222171

45. Spectrum1501148

46. Chebi:9326

47. Sulconazole Nitrate (jan/usp)

48. Chembl1200348

49. Dtxsid2045490

50. Sulconazole Nitrate [mi]

51. Hms500k22

52. Sulconazole Nitrate [jan]

53. Hms1570b21

54. Hms1921l03

55. Hms2092h09

56. Hms2097b21

57. Hms2232b18

58. Hms3370h17

59. Hms3652c18

60. Hms3714b21

61. Pharmakon1600-01501148

62. Sulconazole Nitrate [usan]

63. Sulconazole Nitrate [vandf]

64. Bcp15962

65. Hy-b1460

66. Sulconazole Nitrate [mart.]

67. Tox21_110671

68. Ccg-39015

69. Nsc757849

70. S4120

71. Sulconazole Nitrate [usp-rs]

72. Sulconazole Nitrate [who-dd]

73. Akos015897482

74. Tox21_110671_1

75. Ks-1471

76. Nsc 757849

77. 1-[2-[(4-chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole; Nitric Acid

78. Ncgc00018250-06

79. Ncgc00094911-01

80. Ncgc00094911-02

81. Ncgc00094911-03

82. Ncgc00094911-04

83. Sulconazole Nitrate [orange Book]

84. 1h-imidazole, 1-(2-(((4-chlorophenyl)methyl)thio)-2-(2,4-dichlorophenyl)ethyl)-, Mononitrate, (+-)-

85. 1h-imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, Nitrate (9ci)

86. Ac-26451

87. Sulconazole Nitrate [usp Monograph]

88. Cs-0013167

89. Ft-0659334

90. Sw196439-3

91. U0112

92. D00886

93. Rs-44872-00-1o-3

94. A833159

95. A916203

96. Sr-01000000237-2

97. Sr-01000000237-4

98. Q27252867

99. (+/-)-1-(2,4-dichloro-.beta.-((p-chlorobenzyl)thio)phenethyl)imidazole Mononitrate

100. 1-[2-[(4-chlorophenyl)methylthio]-2-(2,4-dichlorophenyl)ethyl]imidazole; Nitric Acid

101. 1h-imidazole, 1-(2-(((4-chlorophenyl)methyl)thio)-2-(2,4-dichlorophenyl)ethyl)-, Mononitrate, (+/-)-

102. 1h-imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, Nitrate (1:1)

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₈H₁₆Cl₃N₃O₃S
Molecular Weight	460.8 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	458.997796 g/mol
Monoisotopic Mass	458.997796 g/mol
Topological Polar Surface Area	109 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	404
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Exelderm
PubMed Health	Sulconazole (Topical route)
Drug Classes	Antifungal, Imidazole
Drug Label	EXELDERM (sulconazole nitrate, USP) CREAM, 1.0% is a broad-spectrum antifungal agent intended for topical application. Sulconazole nitrate, USP the active ingredient in EXELDERM CREAM, is an imidazole derivative with in vitro antifungal and antiyeast...
Active Ingredient	Sulconazole nitrate
Dosage Form	Cream; Solution
Route	Topical
Strength	1%
Market Status	Prescription
Company	Ranbaxy

2 of 2
Drug Name	Exelderm
PubMed Health	Sulconazole (Topical route)
Drug Classes	Antifungal, Imidazole
Drug Label	EXELDERM (sulconazole nitrate, USP) CREAM, 1.0% is a broad-spectrum antifungal agent intended for topical application. Sulconazole nitrate, USP the active ingredient in EXELDERM CREAM, is an imidazole derivative with in vitro antifungal and antiyeast...
Active Ingredient	Sulconazole nitrate
Dosage Form	Cream; Solution
Route	Topical
Strength	1%
Market Status	Prescription
Company	Ranbaxy

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Antifungal Agents

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Azoles [CS]; Azole Antifungal [EPC]

API SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

NDC API

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

FDF Dossiers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

FDA Orange Book

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

DRUG PRODUCT COMPOSITIONS

Do you need Business Intel? Ask us

DOSAGE - CREAM;TOPICAL - 1%

USFDA APPLICATION NUMBER - 18737

DOSAGE - SOLUTION;TOPICAL - 1%

USFDA APPLICATION NUMBER - 18738

Related Excipient Companies

Upload your portfolio for free, ask us

Excipients by Applications

Click here to find the perfect excipient manufacturers by their capabilities

Solubilizers

Topical

Emulsifying Agents

Thickeners and Stabilizers

Surfactant & Foaming Agents

Co-Processed Excipients

Parenteral

Granulation

Direct Compression

Film Formers & Plasticizers

Lubricants & Glidants

Chewable & Orodispersible Aids

Coating Systems & Additives

Digital Content

Create Content with PharmaCompass, ask us

DATA COMPILATION #PharmaFlow

Global Sales Information

Do you need Business Intel? Ask us

US Medicaid Prescriptions

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Finished Drug Prices

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

REF. STANDARDS & IMPURITIES

Upload your portfolio for free, ask us

USP

Others

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

ABOUT THIS PAGE

Find Sulconazole Nitrate manufacturers, exporters & distributors on PharmaCompass

Sulconazole Nitrate

ACCESS ALL DATA

Browse all information

CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

3 API Suppliers

1 USDMF

1 NDC API

3 Listed Suppliers

FINISHED DOSAGE FORMULATIONS

2 FDF Dossiers

2 FDA Orange Book

DRUG PRODUCT COMPOSITIONS

CREAM;TOPICAL - 1%

SOLUTION;TOPICAL - 1%

RELATED EXCIPIENT COMPANIES

5 Nanjing Well Pharmaceutical

10 BASF

1 Finar

3 Gangwal Chemicals

5 Kerry

1 Microlex e.U

1 Nanjing Bold Chemical

4 Seppic

1 Valens Pharmachem

EXCIPIENTS BY APPLICATIONS

15 Solubilizers

15 Topical

7 Emulsifying Agents

7 Thickeners and Stabilizers

6 Surfactant & Foaming Agents

5 Co-Processed Excipients

4 Parenteral

2 Granulation

2 Direct Compression

2 Film Formers & Plasticizers

2 Lubricants & Glidants

1 Chewable & Orodispersible Aids

1 Coating Systems & Additives

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions

1 Finished Drug Prices

REF. STANDARDS & IMPURITIES

1 USP

1 Others

ACTIVE PHARMA INGREDIENTS

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

GLOBAL SALES INFORMATION

31 RELATED EXCIPIENT COMPANIES

69EXCIPIENTS BY APPLICATIONS

What are you looking for?