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    Chemistry

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    Also known as: 127-56-0, Sodium sulfacetamide, Sulfacetamide sodium anhydrous, Sulamyd sodium, Sulfacetamide (sodium), Sulphacetamide sodium
    Molecular Formula
    C8H9N2NaO3S
    Molecular Weight
    236.23  g/mol
    InChI Key
    PQMSFAORUFMASU-UHFFFAOYSA-M
    FDA UNII
    30760ZE777
    Sulfacetamide Sodium
    An anti-bacterial agent that is used topically to treat skin infections and orally for urinary tract infections.
    1 2D Structure

    Sulfacetamide Sodium

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;acetyl-(4-aminophenyl)sulfonylazanide
    2.1.2 InChI
    InChI=1S/C8H10N2O3S.Na/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;/h2-5H,9H2,1H3,(H,10,11);/q;+1/p-1
    2.1.3 InChI Key
    PQMSFAORUFMASU-UHFFFAOYSA-M
    2.1.4 Canonical SMILES
    CC(=O)[N-]S(=O)(=O)C1=CC=C(C=C1)N.[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    30760ZE777
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Acetopt

    2. Acetylsulfanilamide

    3. Ak Sulf

    4. Ak-sulf

    5. Albucid

    6. Antbor

    7. Belph 10

    8. Belph-10

    9. Bleph

    10. Ceta Sulfa

    11. Cetamide

    12. Colircusi Sulfacetamida

    13. Coliriocilina Sulfacetam

    14. Isopto Cetamide

    15. Sodium Sulamyd

    16. Sulamyd, Sodium

    17. Sulf 10

    18. Sulf-10

    19. Sulfacetam, Coliriocilina

    20. Sulfacetamida, Colircusi

    21. Sulfacetamide

    22. Sulfacetamide Monosodium Salt

    23. Sulfacetamide, Monosodium Salt, Anhydrous

    24. Sulfacil

    25. Sulfacyl

    26. Sulfair

    27. Sulphacetamide

    2.3.2 Depositor-Supplied Synonyms

    1. 127-56-0

    2. Sodium Sulfacetamide

    3. Sulfacetamide Sodium Anhydrous

    4. Sulamyd Sodium

    5. Sulfacetamide (sodium)

    6. Sulphacetamide Sodium

    7. Sodium Sulfanilylacetamide

    8. Klaron

    9. Isopto Cetamide

    10. Sodium N-sulfanilylacetamide

    11. Sodium Sulamyd

    12. Sulfacetamide Sodium Salt

    13. Sulfacylum

    14. Chebi:9327

    15. Sulfair Forte

    16. N-sulfanilylacetamide, Sodium Salt

    17. Ocusulf-10

    18. Sulfair 10

    19. Sulfair-15

    20. Sulten-10

    21. Sulfacetamidum Natricum

    22. Sulf-15

    23. Ocusulf-30

    24. Bleph-30

    25. Sodium Acetyl((4-aminophenyl)sulfonyl)amide

    26. Sodium;acetyl-(4-aminophenyl)sulfonylazanide

    27. 30760ze777

    28. Almocetamide

    29. Sulfableph

    30. Albucide

    31. Antebor

    32. Blefamide

    33. Farmamid

    34. Galseptil

    35. Octsetan

    36. Prontamid

    37. Locula

    38. Albucid Soluble

    39. Sodium Sulfacyl

    40. Sulfacyl Sodium

    41. Beocid-isoptal

    42. Sebizon Lotion

    43. Sodium Albucid

    44. Sulfacyl Sol

    45. Soluble Sulfacyl

    46. Sulfacyl Soluble

    47. Sodium Sulfacetamide, Anhydrous

    48. N-sulfanilylacetamide Sodium

    49. Sulfacetamid Natrium

    50. Minims Sulphacetamide

    51. Soluble Sulfacetamide

    52. Sulfacyl Sodium Salt

    53. Oc-u-mid

    54. Sulf-10 Ophthalmic

    55. Opulets Sulpjacetamide

    56. Sulfacetamide, Sodium

    57. Bleph 10

    58. Sulf 10

    59. Sulfacetamide, Sodium Salt

    60. Acetamide, N-((4-aminophenyl)sulfonyl)-, Sodium Salt (1:1)

    61. Acetamide, N-[(4-aminophenyl)sulfonyl]-, Sodium Salt (1:1)

    62. Albucid-natrium

    63. Unii-30760ze777

    64. Einecs 204-848-4

    65. N(sup 1)-acetylsulfanilamide Sodium

    66. Acetamide, N-sulfanilyl-, Sodium Deriv

    67. Sodium, N(sup 1)-acetylsulfanilamido-

    68. N(sup 1)-acetylsulfanilamide Sodium Salt

    69. Acetamide, N-sulfanilyl-, N-sodium Deriv

    70. Sufacetamide Sodium

    71. Schembl3051698

    72. N(1)-acetylsulfanilamide Sodium

    73. Chembl1200416

    74. Dtxsid40889336

    75. N-acetylsulfanilamide Sodium Salt

    76. N-sulfanilylacetamidemonosodiumsalt

    77. Hms3652g10

    78. Hy-b0576

    79. Bdbm50248189

    80. Mfcd00007885

    81. N(1)-acetylsulfanilamide Sodium Salt

    82. S4081

    83. Sulfacetamide Sodium [who-dd]

    84. Akos003281404

    85. Akos025402286

    86. Sulfacetamide Sodium Salt [mi]

    87. Ac-7629

    88. Ccg-266832

    89. Sodium Acetyl(4-aminophenylsulfonyl)amide

    90. Ac-32699

    91. As-13361

    92. Sodiumacetyl((4-aminophenyl)sulfonyl)amide

    93. Db-041863

    94. N-sulfanilylacetamide Monosodium Salt

    95. Ab00513796

    96. Ft-0631741

    97. S0578

    98. Sw196656-2

    99. Sodium Acetyl[(4-aminophenyl)sulfonyl]azanide

    100. C08051

    101. F12631

    102. N-acetyl-4-aminobenzenesulfonamide Sodium Salt

    103. A906776

    104. Acetamide, N-sulfanilyl-, Monosodium Salt

    105. J-005502

    106. Q27108353

    107. Sulfacetamide Sodium, Pharmaceutical Secondary Standard; Certified Reference Material

    2.4 Create Date
    2005-09-13
    3 Chemical and Physical Properties
    Molecular Weight 236.23 g/mol
    Molecular Formula C8H9N2NaO3S
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count2
    Exact Mass236.02315761 g/mol
    Monoisotopic Mass236.02315761 g/mol
    Topological Polar Surface Area86.6 Ų
    Heavy Atom Count15
    Formal Charge0
    Complexity304
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameSulfacetamide sodium
    Drug LabelFOR EXTERNAL USE ONLY. NOT FOR OPHTHALMIC USE.DESCRIPTION:Each gram of OVACE Plus Shampoo (sodium sulfacetamide 10% w/w) contains 100 mg of sodium sulfacetamide in a vehicle consisting of cetearyl alcohol (and) PEG-3 distearoylamidoethylmonium meth...
    Active IngredientSulfacetamide sodium
    Dosage FormSolution/drops; Ointment; Lotion
    RouteOphthalmic; Topical
    Strength10%
    Market StatusPrescription
    CompanyPerrigo Co Tennessee; Taro; Fougera Pharms; Bausch And Lomb; Alcon Pharms

    2 of 2  
    Drug NameSulfacetamide sodium
    Drug LabelFOR EXTERNAL USE ONLY. NOT FOR OPHTHALMIC USE.DESCRIPTION:Each gram of OVACE Plus Shampoo (sodium sulfacetamide 10% w/w) contains 100 mg of sodium sulfacetamide in a vehicle consisting of cetearyl alcohol (and) PEG-3 distearoylamidoethylmonium meth...
    Active IngredientSulfacetamide sodium
    Dosage FormSolution/drops; Ointment; Lotion
    RouteOphthalmic; Topical
    Strength10%
    Market StatusPrescription
    CompanyPerrigo Co Tennessee; Taro; Fougera Pharms; Bausch And Lomb; Alcon Pharms

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

    Anti-Infective Agents, Local

    Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects. (See all compounds classified as Anti-Infective Agents, Local.)

    Anti-Infective Agents, Urinary

    Substances capable of killing agents causing urinary tract infections or of preventing them from spreading. (See all compounds classified as Anti-Infective Agents, Urinary.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Sulfonamides [CS]; Sulfonamide Antibacterial [EPC]

    API Reference Price

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    FDA Orange Book

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    01

    ALLERGAN

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    RLD : Yes

    TE Code :

    PREDNISOLONE ACETATE; SULFACETAMIDE SODIUM

    Brand Name : BLEPHAMIDE

    Dosage Form : SUSPENSION;OPHTHALMIC

    Dosage Strength : 0.2%;10%

    Approval Date : 1982-01-01

    Application Number : 12813

    RX/OTC/DISCN : DISCN

    RLD : Yes

    TE Code :

    Abbvie CB

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    RLD : No

    TE Code :

    FLUOROMETHOLONE; SULFACETAMIDE SODIUM

    Brand Name : FML-S

    Dosage Form : SUSPENSION/DROPS;OPHTHALMIC

    Dosage Strength : 0.1%;10%

    Approval Date : 1989-09-29

    Application Number : 19525

    RX/OTC/DISCN : DISCN

    RLD : No

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    RLD : Yes

    TE Code :

    SULFACETAMIDE SODIUM

    Brand Name : BLEPH-10

    Dosage Form : SOLUTION/DROPS;OPHTHALMIC

    Dosage Strength : 10%

    Approval Date : 1982-01-01

    Application Number : 80028

    RX/OTC/DISCN : DISCN

    RLD : Yes

    TE Code :

    Abbvie CB

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    04

    ALLERGAN

    U.S.A
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    Antibody Engineering
    Not Confirmed
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    RLD : No

    TE Code :

    SULFACETAMIDE SODIUM

    Brand Name : BLEPH-30

    Dosage Form : SOLUTION/DROPS;OPHTHALMIC

    Dosage Strength : 30%

    Approval Date : 1982-01-01

    Application Number : 80028

    RX/OTC/DISCN : DISCN

    RLD : No

    TE Code :

    Abbvie CB

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    05

    ALLERGAN

    U.S.A
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    Antibody Engineering
    Not Confirmed
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    RLD : No

    TE Code :

    SULFACETAMIDE SODIUM

    Brand Name : BLEPH-10

    Dosage Form : OINTMENT;OPHTHALMIC

    Dosage Strength : 10%

    Approval Date : 1982-01-01

    Application Number : 84015

    RX/OTC/DISCN : DISCN

    RLD : No

    TE Code :

    Abbvie CB

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    06

    ALLERGAN

    U.S.A
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    Antibody Engineering
    Not Confirmed
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    RLD : No

    TE Code :

    PREDNISOLONE ACETATE; SULFACETAMIDE SODIUM

    Brand Name : BLEPHAMIDE S.O.P.

    Dosage Form : OINTMENT;OPHTHALMIC

    Dosage Strength : 0.2%;10%

    Approval Date : 1986-12-03

    Application Number : 87748

    RX/OTC/DISCN : DISCN

    RLD : No

    TE Code :

    Abbvie CB

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    07

    ALCON

    U.S.A
    Antibody Engineering
    Not Confirmed
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    ALCON

    U.S.A
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    RLD : No

    TE Code :

    SULFACETAMIDE SODIUM

    Brand Name : CETAMIDE

    Dosage Form : OINTMENT;OPHTHALMIC

    Dosage Strength : 10%

    Approval Date : 1982-01-01

    Application Number : 80021

    RX/OTC/DISCN : DISCN

    RLD : No

    TE Code :

    blank

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    08

    PHARMAFAIR

    Canada
    Antibody Engineering
    Not Confirmed
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    PHARMAFAIR

    Canada
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    Antibody Engineering
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    RLD : No

    TE Code :

    SULFACETAMIDE SODIUM

    Brand Name : SULFAIR 10

    Dosage Form : SOLUTION/DROPS;OPHTHALMIC

    Dosage Strength : 10%

    Approval Date : 1982-12-13

    Application Number : 87949

    RX/OTC/DISCN : DISCN

    RLD : No

    TE Code :

    blank

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    09

    PHARMAFAIR

    Canada
    Antibody Engineering
    Not Confirmed
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    PHARMAFAIR

    Canada
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    Antibody Engineering
    Not Confirmed
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    • EDQM
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    RLD : No

    TE Code :

    SULFACETAMIDE SODIUM

    Brand Name : SULFACETAMIDE SODIUM

    Dosage Form : SOLUTION/DROPS;OPHTHALMIC

    Dosage Strength : 10%

    Approval Date : 1985-05-17

    Application Number : 88947

    RX/OTC/DISCN : DISCN

    RLD : No

    TE Code :

    blank

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    10

    SCHERING

    Germany
    Antibody Engineering
    Not Confirmed
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    SCHERING

    Germany
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    Antibody Engineering
    Not Confirmed
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    RLD : Yes

    TE Code :

    SULFACETAMIDE SODIUM

    Brand Name : SODIUM SULAMYD

    Dosage Form : SOLUTION/DROPS;OPHTHALMIC

    Dosage Strength : 10% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    Approval Date : 1982-01-01

    Application Number : 5963

    RX/OTC/DISCN : DISCN

    RLD : Yes

    TE Code :

    blank

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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - SUSPENSION;OPHTHALMIC - 0.2%;10%

    USFDA APPLICATION NUMBER - 12813

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    DOSAGE - SOLUTION/DROPS;OPHTHALMIC - 10%

    USFDA APPLICATION NUMBER - 80028

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