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Chemistry

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Also known as: 127-56-0, Sodium sulfacetamide, Sulfacetamide sodium anhydrous, Sulamyd sodium, Sulfacetamide (sodium), Sulphacetamide sodium
Molecular Formula
C8H9N2NaO3S
Molecular Weight
236.23  g/mol
InChI Key
PQMSFAORUFMASU-UHFFFAOYSA-M
FDA UNII
30760ZE777

Sulfacetamide Sodium
An anti-bacterial agent that is used topically to treat skin infections and orally for urinary tract infections.
1 2D Structure

Sulfacetamide Sodium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;acetyl-(4-aminophenyl)sulfonylazanide
2.1.2 InChI
InChI=1S/C8H10N2O3S.Na/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;/h2-5H,9H2,1H3,(H,10,11);/q;+1/p-1
2.1.3 InChI Key
PQMSFAORUFMASU-UHFFFAOYSA-M
2.1.4 Canonical SMILES
CC(=O)[N-]S(=O)(=O)C1=CC=C(C=C1)N.[Na+]
2.2 Other Identifiers
2.2.1 UNII
30760ZE777
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Acetopt

2. Acetylsulfanilamide

3. Ak Sulf

4. Ak-sulf

5. Albucid

6. Antbor

7. Belph 10

8. Belph-10

9. Bleph

10. Ceta Sulfa

11. Cetamide

12. Colircusi Sulfacetamida

13. Coliriocilina Sulfacetam

14. Isopto Cetamide

15. Sodium Sulamyd

16. Sulamyd, Sodium

17. Sulf 10

18. Sulf-10

19. Sulfacetam, Coliriocilina

20. Sulfacetamida, Colircusi

21. Sulfacetamide

22. Sulfacetamide Monosodium Salt

23. Sulfacetamide, Monosodium Salt, Anhydrous

24. Sulfacil

25. Sulfacyl

26. Sulfair

27. Sulphacetamide

2.3.2 Depositor-Supplied Synonyms

1. 127-56-0

2. Sodium Sulfacetamide

3. Sulfacetamide Sodium Anhydrous

4. Sulamyd Sodium

5. Sulfacetamide (sodium)

6. Sulphacetamide Sodium

7. Sodium Sulfanilylacetamide

8. Klaron

9. Isopto Cetamide

10. Sodium N-sulfanilylacetamide

11. Sodium Sulamyd

12. Sulfacetamide Sodium Salt

13. Sulfacylum

14. Chebi:9327

15. Sulfair Forte

16. N-sulfanilylacetamide, Sodium Salt

17. Ocusulf-10

18. Sulfair 10

19. Sulfair-15

20. Sulten-10

21. Sulfacetamidum Natricum

22. Sulf-15

23. Ocusulf-30

24. Bleph-30

25. Sodium Acetyl((4-aminophenyl)sulfonyl)amide

26. Sodium;acetyl-(4-aminophenyl)sulfonylazanide

27. 30760ze777

28. Almocetamide

29. Sulfableph

30. Albucide

31. Antebor

32. Blefamide

33. Farmamid

34. Galseptil

35. Octsetan

36. Prontamid

37. Locula

38. Albucid Soluble

39. Sodium Sulfacyl

40. Sulfacyl Sodium

41. Beocid-isoptal

42. Sebizon Lotion

43. Sodium Albucid

44. Sulfacyl Sol

45. Soluble Sulfacyl

46. Sulfacyl Soluble

47. Sodium Sulfacetamide, Anhydrous

48. N-sulfanilylacetamide Sodium

49. Sulfacetamid Natrium

50. Minims Sulphacetamide

51. Soluble Sulfacetamide

52. Sulfacyl Sodium Salt

53. Oc-u-mid

54. Sulf-10 Ophthalmic

55. Opulets Sulpjacetamide

56. Sulfacetamide, Sodium

57. Bleph 10

58. Sulf 10

59. Sulfacetamide, Sodium Salt

60. Acetamide, N-((4-aminophenyl)sulfonyl)-, Sodium Salt (1:1)

61. Acetamide, N-[(4-aminophenyl)sulfonyl]-, Sodium Salt (1:1)

62. Albucid-natrium

63. Unii-30760ze777

64. Einecs 204-848-4

65. N(sup 1)-acetylsulfanilamide Sodium

66. Acetamide, N-sulfanilyl-, Sodium Deriv

67. Sodium, N(sup 1)-acetylsulfanilamido-

68. N(sup 1)-acetylsulfanilamide Sodium Salt

69. Acetamide, N-sulfanilyl-, N-sodium Deriv

70. Sufacetamide Sodium

71. Schembl3051698

72. N(1)-acetylsulfanilamide Sodium

73. Chembl1200416

74. Dtxsid40889336

75. N-acetylsulfanilamide Sodium Salt

76. N-sulfanilylacetamidemonosodiumsalt

77. Hms3652g10

78. Hy-b0576

79. Bdbm50248189

80. Mfcd00007885

81. N(1)-acetylsulfanilamide Sodium Salt

82. S4081

83. Sulfacetamide Sodium [who-dd]

84. Akos003281404

85. Akos025402286

86. Sulfacetamide Sodium Salt [mi]

87. Ac-7629

88. Ccg-266832

89. Sodium Acetyl(4-aminophenylsulfonyl)amide

90. Ac-32699

91. As-13361

92. Sodiumacetyl((4-aminophenyl)sulfonyl)amide

93. Db-041863

94. N-sulfanilylacetamide Monosodium Salt

95. Ab00513796

96. Ft-0631741

97. S0578

98. Sw196656-2

99. Sodium Acetyl[(4-aminophenyl)sulfonyl]azanide

100. C08051

101. F12631

102. N-acetyl-4-aminobenzenesulfonamide Sodium Salt

103. A906776

104. Acetamide, N-sulfanilyl-, Monosodium Salt

105. J-005502

106. Q27108353

107. Sulfacetamide Sodium, Pharmaceutical Secondary Standard; Certified Reference Material

2.4 Create Date
2005-09-13
3 Chemical and Physical Properties
Molecular Weight 236.23 g/mol
Molecular Formula C8H9N2NaO3S
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass236.02315761 g/mol
Monoisotopic Mass236.02315761 g/mol
Topological Polar Surface Area86.6 Ų
Heavy Atom Count15
Formal Charge0
Complexity304
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameSulfacetamide sodium
Drug LabelFOR EXTERNAL USE ONLY. NOT FOR OPHTHALMIC USE.DESCRIPTION:Each gram of OVACE Plus Shampoo (sodium sulfacetamide 10% w/w) contains 100 mg of sodium sulfacetamide in a vehicle consisting of cetearyl alcohol (and) PEG-3 distearoylamidoethylmonium meth...
Active IngredientSulfacetamide sodium
Dosage FormSolution/drops; Ointment; Lotion
RouteOphthalmic; Topical
Strength10%
Market StatusPrescription
CompanyPerrigo Co Tennessee; Taro; Fougera Pharms; Bausch And Lomb; Alcon Pharms

2 of 2  
Drug NameSulfacetamide sodium
Drug LabelFOR EXTERNAL USE ONLY. NOT FOR OPHTHALMIC USE.DESCRIPTION:Each gram of OVACE Plus Shampoo (sodium sulfacetamide 10% w/w) contains 100 mg of sodium sulfacetamide in a vehicle consisting of cetearyl alcohol (and) PEG-3 distearoylamidoethylmonium meth...
Active IngredientSulfacetamide sodium
Dosage FormSolution/drops; Ointment; Lotion
RouteOphthalmic; Topical
Strength10%
Market StatusPrescription
CompanyPerrigo Co Tennessee; Taro; Fougera Pharms; Bausch And Lomb; Alcon Pharms

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


Anti-Infective Agents, Local

Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects. (See all compounds classified as Anti-Infective Agents, Local.)


Anti-Infective Agents, Urinary

Substances capable of killing agents causing urinary tract infections or of preventing them from spreading. (See all compounds classified as Anti-Infective Agents, Urinary.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Sulfonamides [CS]; Sulfonamide Antibacterial [EPC]

API Reference Price

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12-Feb-2021
12-Aug-2024
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DOSAGE - SUSPENSION;OPHTHALMIC - 0.2%;10%

USFDA APPLICATION NUMBER - 12813

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