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Chemistry

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Also known as: Sulphadimethoxine, 122-11-2, Sulfadimethoxin, Sulfadimethoxydiazine, Sulfadimetoxin, Albon
Molecular Formula
C12H14N4O4S
Molecular Weight
310.33  g/mol
InChI Key
ZZORFUFYDOWNEF-UHFFFAOYSA-N
FDA UNII
30CPC5LDEX

Sulfadimethoxine
A sulfanilamide that is used as an anti-infective agent.
1 2D Structure

Sulfadimethoxine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
2.1.2 InChI
InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
2.1.3 InChI Key
ZZORFUFYDOWNEF-UHFFFAOYSA-N
2.1.4 Canonical SMILES
COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)OC
2.2 Other Identifiers
2.2.1 UNII
30CPC5LDEX
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Deposul

2. Sulphadimethoxine

2.3.2 Depositor-Supplied Synonyms

1. Sulphadimethoxine

2. 122-11-2

3. Sulfadimethoxin

4. Sulfadimethoxydiazine

5. Sulfadimetoxin

6. Albon

7. 4-amino-n-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide

8. 4-amino-n-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide

9. Dimetazina

10. Sulfadimetoxina

11. Agribon

12. Deposul

13. Madribon

14. Sulfadimethoxinum

15. Arnosulfan

16. Bactrovet

17. Diasulfa

18. Diasulfyl

19. Dimethoxysulfadiazine

20. Madrigid

21. Madriqid

22. Madroxin

23. Madroxine

24. Maxulvet

25. Memcozine

26. Metoxidon

27. Neostrepal

28. Persulfen

29. Roscosulf

30. Scandisil

31. Sulfastop

32. Sulfoplan

33. Theracanzan

34. Dinosol

35. Dorisul

36. Omnibon

37. Radonin

38. Redifal

39. Sudine

40. Sulxin

41. Symbio

42. Abcid

43. Fuxal

44. Sulfadimetossina

45. 2,6-dimethoxy-4-sulfanilamidopyrimidine

46. Benzenesulfonamide, 4-amino-n-(2,6-dimethoxy-4-pyrimidinyl)-

47. 2,4-dimethoxy-6-sulfanilamido-1,3-diazine

48. 6-sulfanilamido-2,4-dimethoxypyrimidine

49. Agribon (tn)

50. Abcid (tn)

51. 2,6-dimethoxy-4-(p-aminobenzenesulfonamido)pyrimidine

52. Nsc 683544

53. Chebi:32161

54. 4-amino-n-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide

55. N1-(2,6-dimethoxy-4-pyrimidinyl)sulfanilamide

56. 30cpc5ldex

57. Nsc-683544

58. Nsc-757860

59. N(sup 1)-(2,6-dimethoxy-4-pyrimidinyl)sulfanilamide

60. Mls000069720

61. N(1)-(2,6-dimethoxy-4-pyrimidinyl)sulfanilamide

62. Nsc683544

63. Sulfanilamide, N(sup 1)-(2,6-dimethoxy-4-pyrimidinyl)-

64. Ncgc00016375-01

65. Cas-122-11-2

66. Smr000017367

67. Solfadimetossina

68. Dsstox_cid_3607

69. Dsstox_rid_77105

70. Dsstox_gsid_23607

71. Sulfadimetoxine

72. Neostreptal

73. Sulfadimoxine

74. Suldixine

75. Sulfabon

76. Sulfadimethoxine [jan]

77. Solfadimetossina [dcit]

78. Sulfadimetossina [italian]

79. Sulfadimethoxinum [inn-latin]

80. Sulfadimetoxina [inn-spanish]

81. Sulfamed-g

82. Sr-01000000227

83. Einecs 204-523-7

84. Unii-30cpc5ldex

85. Brn 0306856

86. Ultrasulfon

87. Lasibon

88. Mecozine

89. Sumbio

90. Sdmo

91. Ccris 9326

92. Prestwick_979

93. Mfcd00057345

94. Rofenaid (salt/mix)

95. 4-amino-n-(2,6-dimethoxy-4-pyrimidinyl)benzolsulfonamid

96. Spectrum_001408

97. Sulfadimethoxine [usp:inn:ban:jan:nf]

98. Opera_id_1856

99. Prestwick0_000728

100. Prestwick1_000728

101. Prestwick2_000728

102. Prestwick3_000728

103. Spectrum2_001419

104. Spectrum3_001454

105. Spectrum4_000442

106. Spectrum5_001221

107. Cbkinase1_000256

108. Cbkinase1_012656

109. Epitope Id:122237

110. Cambridge Id 5251398

111. Oprea1_486812

112. Oprea1_495206

113. Schembl93845

114. Sulfadimethoxine (jan/usp)

115. Bspbio_000656

116. Bspbio_002947

117. Kbiogr_000824

118. Kbioss_001888

119. Sulfadimethoxine [mi]

120. 5-25-13-00290 (beilstein Handbook Reference)

121. Mls000103402

122. Mls000104965

123. Mls001148602

124. Chembl62193

125. Divk1c_000088

126. Spectrum1501144

127. Sulfadimethoxine [inn]

128. Spbio_001498

129. Spbio_002595

130. Bpbio1_000722

131. Component Of Prazil (salt/mix)

132. Component Of Primor (salt/mix)

133. Dtxsid1023607

134. Sulfadimethoxine [mart.]

135. Hms500e10

136. Kbio1_000088

137. Kbio2_001888

138. Kbio2_004456

139. Kbio2_007024

140. Kbio3_002447

141. 4-sulfa-2,6-dimethoxypyrimidine

142. Sulfadimethoxine [usp-rs]

143. Sulfadimethoxine [who-dd]

144. Component Of Maxutrim (salt/mix)

145. Component Of Rofenaid (salt/mix)

146. Ninds_000088

147. [(4-aminophenyl)sulfonyl](2,6-dimethoxypyrimidin-4-yl)amine

148. Hms1570a18

149. Hms1921j15

150. Hms2090p11

151. Hms2092f21

152. Hms2097a18

153. Hms2230l05

154. Hms3370k02

155. Hms3655h05

156. Hms3714a18

157. Pharmakon1600-01501144

158. Component Of Trivalbon (salt/mix)

159. Bcp15413

160. Hy-b0337

161. Tox21_110405

162. Bbl023015

163. Ccg-38972

164. Nsc757860

165. S1962

166. Stk018258

167. Sulfadimethoxine [green Book]

168. Zinc13233295

169. Akos000485038

170. Tox21_110405_1

171. Db06150

172. Ks-5335

173. Sulfadimethoxine [usp Impurity]

174. Sulfadimethoxine For Peak Identification

175. 4-sulfanilamido-2,6-dimethoxypyrimidine

176. Idi1_000088

177. Smp2_000079

178. Sulfadimethoxine [usp Monograph]

179. 2,4-dimethoxy-6-sulfanilamidopyrimidine

180. Ncgc00016375-02

181. Ncgc00016375-03

182. Ncgc00016375-04

183. Ncgc00016375-05

184. Ncgc00016375-06

185. Ncgc00016375-09

186. Ncgc00016375-10

187. Ncgc00024020-03

188. Ncgc00024020-04

189. Ac-10998

190. Sbi-0051656.p002

191. Sulfadimethoxine 100 Microg/ml In Methanol

192. 6-sulfanilamido-2,4-dimethoxy-1,3-diazine

193. Ab00052219

194. B3301

195. Ft-0603324

196. Sulfadimethoxine 1000 Microg/ml In Methanol

197. Sw149624-4

198. 2,4-dimethoxy-6-sulfanilamido-1,3-pyrimidine

199. 22s112

200. D01142

201. H10770

202. Sulfadimethoxine 100 Microg/ml In Acetonitrile

203. Ab00052219-15

204. Ab00052219-17

205. Ab00052219_18

206. Ab00052219_19

207. A804847

208. J-004764

209. Q4921678

210. Sr-01000000227-2

211. Sr-01000000227-4

212. Sulfadimethoxine, Vetranal(tm), Analytical Standard

213. Sulfanilamide, N1-(2,6-dimethoxy-4-pyrimidinyl)-

214. 4-(p-aminobenzenesulfonamido)-2,6-dimethoxypyrimidine

215. Brd-k71125014-001-05-7

216. Brd-k71125014-001-07-3

217. Brd-k71125014-001-17-2

218. N(sup1)-(2,6-dimethoxy-4-pyrimidinyl)sulfanilamide

219. Sulfadimethoxine, Analytical Standard, >=98.5% (tlc)

220. 4-amino-n-[2,6-bis(methyloxy)pyrimidin-4-yl]benzenesulfonamide

221. Sulfadimethoxine, European Pharmacopoeia (ep) Reference Standard

222. Sulfadimethoxine, United States Pharmacopeia (usp) Reference Standard

223. Sulfadimethoxine For Peak Identification, European Pharmacopoeia (ep) Reference Standard

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 310.33 g/mol
Molecular Formula C12H14N4O4S
XLogP31.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass310.07357611 g/mol
Monoisotopic Mass310.07357611 g/mol
Topological Polar Surface Area125 Ų
Heavy Atom Count21
Formal Charge0
Complexity420
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

For use in the treatment of infections.


5 Pharmacology and Biochemistry
5.1 Pharmacology

Sulfadimethoxine has been shown to be effective against streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.


5.2 MeSH Pharmacological Classification

Anti-Infective Agents

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)


5.3 ATC Code

J01ED02

S66 | EAWAGTPS | Parent-Transformation Product Pairs from Eawag | DOI:10.5281/zenodo.3754448


J01ED02

S66 | EAWAGTPS | Parent-Transformation Product Pairs from Eawag | DOI:10.5281/zenodo.3754448


J - Antiinfectives for systemic use

J01 - Antibacterials for systemic use

J01E - Sulfonamides and trimethoprim

J01ED - Long-acting sulfonamides

J01ED01 - Sulfadimethoxine


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29-Jan-2021
30-Jul-2024
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ABOUT THIS PAGE

Sulfadimethoxine Manufacturers

A Sulfadimethoxine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sulfadimethoxine, including repackagers and relabelers. The FDA regulates Sulfadimethoxine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sulfadimethoxine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Sulfadimethoxine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Sulfadimethoxine Suppliers

A Sulfadimethoxine supplier is an individual or a company that provides Sulfadimethoxine active pharmaceutical ingredient (API) or Sulfadimethoxine finished formulations upon request. The Sulfadimethoxine suppliers may include Sulfadimethoxine API manufacturers, exporters, distributors and traders.

click here to find a list of Sulfadimethoxine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sulfadimethoxine USDMF

A Sulfadimethoxine DMF (Drug Master File) is a document detailing the whole manufacturing process of Sulfadimethoxine active pharmaceutical ingredient (API) in detail. Different forms of Sulfadimethoxine DMFs exist exist since differing nations have different regulations, such as Sulfadimethoxine USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Sulfadimethoxine DMF submitted to regulatory agencies in the US is known as a USDMF. Sulfadimethoxine USDMF includes data on Sulfadimethoxine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Sulfadimethoxine USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Sulfadimethoxine suppliers with USDMF on PharmaCompass.

Sulfadimethoxine CEP

A Sulfadimethoxine CEP of the European Pharmacopoeia monograph is often referred to as a Sulfadimethoxine Certificate of Suitability (COS). The purpose of a Sulfadimethoxine CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Sulfadimethoxine EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Sulfadimethoxine to their clients by showing that a Sulfadimethoxine CEP has been issued for it. The manufacturer submits a Sulfadimethoxine CEP (COS) as part of the market authorization procedure, and it takes on the role of a Sulfadimethoxine CEP holder for the record. Additionally, the data presented in the Sulfadimethoxine CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Sulfadimethoxine DMF.

A Sulfadimethoxine CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Sulfadimethoxine CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Sulfadimethoxine suppliers with CEP (COS) on PharmaCompass.

Sulfadimethoxine NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Sulfadimethoxine as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Sulfadimethoxine API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Sulfadimethoxine as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Sulfadimethoxine and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Sulfadimethoxine NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Sulfadimethoxine suppliers with NDC on PharmaCompass.

Sulfadimethoxine GMP

Sulfadimethoxine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sulfadimethoxine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sulfadimethoxine GMP manufacturer or Sulfadimethoxine GMP API supplier for your needs.

Sulfadimethoxine CoA

A Sulfadimethoxine CoA (Certificate of Analysis) is a formal document that attests to Sulfadimethoxine's compliance with Sulfadimethoxine specifications and serves as a tool for batch-level quality control.

Sulfadimethoxine CoA mostly includes findings from lab analyses of a specific batch. For each Sulfadimethoxine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sulfadimethoxine may be tested according to a variety of international standards, such as European Pharmacopoeia (Sulfadimethoxine EP), Sulfadimethoxine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sulfadimethoxine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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