Synopsis
Synopsis
0
JDMF
0
KDMF
0
VMF
0
Europe
0
Australia
DRUG PRODUCT COMPOSITIONS
0
US Patents
0
US Exclusivities
0
Health Canada Patents
0
Data Compilation #PharmaFlow
0
Stock Recap #PipelineProspector
0
Weekly News Recap #Phispers
US Medicaid
NA
Annual Reports
NA
Finished Drug Prices
NA
1. Fanasil
2. Ro 4 4393
3. Ro 4-4393
4. Ro 44393
5. Sulformethoxine
6. Sulformetoxine
7. Sulforthomidine
8. Sulphormetoxin
9. Sulphorthodimethoxine
1. 2447-57-6
2. Sulphadoxine
3. Sulforthomidine
4. Sulfadoxin
5. 4-amino-n-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
6. Fanasil
7. Sulphormethoxine
8. Sulfadoxinum
9. Sulfadoxina
10. Fanzil
11. Ro 4-4393
12. 4-amino-n-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
13. 4-sulfanilamido-5,6-dimethoxypyrimidine
14. Benzenesulfonamide, 4-amino-n-(5,6-dimethoxy-4-pyrimidinyl)-
15. Fanasulf
16. N'-(5,6-dimethoxy-4-pyrimidyl)sulfanilamide
17. 6-(4-aminobenzenesulfonamido)-4,5-dimethoxypyrimidine
18. Sulfadoxine (sulphadoxine)
19. Nsc-759319
20. Ro-4-4393
21. Chebi:9329
22. Solfadossina
23. 4-amino-n-(5,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide
24. Sulfadoxine-d3
25. Ro-44393
26. 88463u4sm5
27. Wr-4073
28. Ncgc00016612-01
29. Orthosulfin
30. J21.373j
31. Cas-2447-57-6
32. Solfadossina [dcit]
33. Dsstox_cid_3608
34. Dsstox_rid_77106
35. Dsstox_gsid_23608
36. Sulfadoxinum [inn-latin]
37. Sulfadoxina [inn-spanish]
38. 4-amino-n-[5,6-bis(methyloxy)pyrimidin-4-yl]benzenesulfonamide
39. Wr 4873
40. Sr-05000001523
41. Einecs 219-504-9
42. N1-(5,6-dimethoxy-4-pyrimidinyl)sulfanilamide
43. Brn 0625453
44. Sulfadoxine (jan/usp/inn)
45. Unii-88463u4sm5
46. Sanasil: Sulfadoxine: Sulformetoxin
47. Mfcd00792890
48. N(sup 1)-(5,6-dimethoxy-4-pyrimidinyl)sulfanilamide
49. Wr 4073
50. Sulfadoxine [usan:usp:inn:ban:jan]
51. Sulfadoxine [mi]
52. Prestwick0_001094
53. Prestwick1_001094
54. Prestwick2_001094
55. Prestwick3_001094
56. Sulfadoxine [inn]
57. Sulfadoxine [jan]
58. Sulfadoxine [usan]
59. Sulfadoxine [vandf]
60. Chembl1539
61. Sulfadoxine [mart.]
62. Schembl41069
63. Bspbio_001168
64. Sulfadoxine [usp-rs]
65. Sulfadoxine [who-dd]
66. Sulfadoxine [who-ip]
67. 5-25-13-00306 (beilstein Handbook Reference)
68. Mls002154150
69. Spbio_003054
70. Bpbio1_001286
71. Zinc2094
72. Sulfadoxin, >=95% (tlc)
73. Dtxsid6023608
74. Gtpl10173
75. Sulfadoxine [orange Book]
76. Hms1571k10
77. Hms2090p07
78. Hms2094c19
79. Hms2098k10
80. Hms2230e05
81. Hms3371i15
82. Hms3715k10
83. Pharmakon1600-01506086
84. Sulfadoxine [ep Monograph]
85. Sulfadoxine [usp Monograph]
86. Hy-b0439
87. Sulfadoxinum [who-ip Latin]
88. Tox21_110523
89. Bbl023187
90. Fansidar Component Sulfadoxine
91. Nsc759319
92. S2511
93. Stl356042
94. Akos015897281
95. Sulfadoxin 100 Microg/ml In Methanol
96. Tox21_110523_1
97. Ac-8428
98. Ccg-213610
99. Db01299
100. Ks-5334
101. Nsc 759319
102. Sulfadoxine Component Of Fansidar
103. Ncgc00016612-02
104. Ncgc00016612-04
105. Ncgc00016612-05
106. Sulfadoxine 1000 Microg/ml In Methanol
107. Smr000857259
108. Sbi-0206941.p001
109. Sulfadoxine 100 Microg/ml In Acetonitrile
110. Db-046463
111. Ab00514044
112. Ft-0603610
113. N1-5,6-dimethoxy-4-pyrimidinylsulfanilamide
114. 47s576
115. C07630
116. D00580
117. H10765
118. Sulfadoxin, Vetranal(tm), Analytical Standard
119. Ab00514044-06
120. Ab00514044_07
121. Ab00514044_08
122. A817328
123. Q411557
124. Sr-05000001523-1
125. Sr-05000001523-3
126. W-107313
127. Brd-k55250441-001-03-1
128. Brd-k55250441-001-06-4
129. Sulfadoxin, Certified Reference Material, Tracecert(r)
130. 4-amino-n-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide;
131. 4-azanyl-n-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
132. Sulfadoxine, European Pharmacopoeia (ep) Reference Standard
133. Sulfadoxine, United States Pharmacopeia (usp) Reference Standard
| Molecular Weight | 310.33 g/mol |
|---|---|
| Molecular Formula | C12H14N4O4S |
| XLogP3 | 0.7 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 5 |
| Exact Mass | 310.07357611 g/mol |
| Monoisotopic Mass | 310.07357611 g/mol |
| Topological Polar Surface Area | 125 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 420 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Sulfadoxine is used in combination with pyrimethamine for the treatment or prevention of malaria. It can also be used to treat various infections in livestock as well. Sulfadoxine and pyrimethamine is indicated for the treatment of Plasmodium falciparum malaria in those patients in whom chloroquine resistance is suspected.
Sulfadoxine helps inhibit the enzyme dihydropteroate synthetase which is an enzyme necessary in the conversion of PABA to folic acid. As folic acid is vital to the synthesis, repair, and methylation of DNA which is vital to cell growth in Plasmodium falciparum. With this vital nutrient lacking, the parasite has difficulty in reproducing.
Anti-Infective Agents, Urinary
Substances capable of killing agents causing urinary tract infections or of preventing them from spreading. (See all compounds classified as Anti-Infective Agents, Urinary.)
Anti-Infective Agents
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)
Antimalarials
Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585) (See all compounds classified as Antimalarials.)
Sulfadoxine is a sulfa drug, often used in combination with pyrimethamine to treat malaria. This medicine may also be used to prevent malaria in people who are living in, or will be traveling to, an area where there is a chance of getting malaria. Sulfadoxine targets Plasmodium dihydropteroate synthase and dihydrofolate reductase. Sulfa drugs or Sulfonamides are antimetabolites. They compete with para-aminobenzoic acid (PABA) for incorporation into folic acid. The action of sulfonamides exploits the difference between mammal cells and other kinds of cells in their folic acid metabolism. All cells require folic acid for growth. Folic acid (as a vitamin) diffuses or is transported into human cells. However, folic acid cannot cross bacterial (and certain protozoan) cell walls by diffusion or active transport. For this reason bacteria must synthesize folic acid from p-aminobenzoic acid.
API SUPPLIERS
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]
USDMF
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]CEP/COS
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results] EU WC
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]NDC API
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Listed Suppliers
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]API Reference Price
API Imports and Exports
| Importing Country | Total Quantity (KGS) |
Average Price (USD/KGS) |
Number of Transactions |
|---|
Upgrade, download data, analyse, strategize, subscribe with us 
INTERMEDIATES SUPPLIERS
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]FDF Dossiers
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]FDA Orange Book
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Canada
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Digital Content
NEWS #PharmaBuzz
Market Place
REF. STANDARDS & IMPURITIES
ABOUT THIS PAGE
A Sulfadoxine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sulfadoxine, including repackagers and relabelers. The FDA regulates Sulfadoxine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sulfadoxine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Sulfadoxine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Sulfadoxine supplier is an individual or a company that provides Sulfadoxine active pharmaceutical ingredient (API) or Sulfadoxine finished formulations upon request. The Sulfadoxine suppliers may include Sulfadoxine API manufacturers, exporters, distributors and traders.
click here to find a list of Sulfadoxine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Sulfadoxine DMF (Drug Master File) is a document detailing the whole manufacturing process of Sulfadoxine active pharmaceutical ingredient (API) in detail. Different forms of Sulfadoxine DMFs exist exist since differing nations have different regulations, such as Sulfadoxine USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Sulfadoxine DMF submitted to regulatory agencies in the US is known as a USDMF. Sulfadoxine USDMF includes data on Sulfadoxine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Sulfadoxine USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Sulfadoxine suppliers with USDMF on PharmaCompass.
A Sulfadoxine CEP of the European Pharmacopoeia monograph is often referred to as a Sulfadoxine Certificate of Suitability (COS). The purpose of a Sulfadoxine CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Sulfadoxine EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Sulfadoxine to their clients by showing that a Sulfadoxine CEP has been issued for it. The manufacturer submits a Sulfadoxine CEP (COS) as part of the market authorization procedure, and it takes on the role of a Sulfadoxine CEP holder for the record. Additionally, the data presented in the Sulfadoxine CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Sulfadoxine DMF.
A Sulfadoxine CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Sulfadoxine CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.
click here to find a list of Sulfadoxine suppliers with CEP (COS) on PharmaCompass.
A Sulfadoxine written confirmation (Sulfadoxine WC) is an official document issued by a regulatory agency to a Sulfadoxine manufacturer, verifying that the manufacturing facility of a Sulfadoxine active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Sulfadoxine APIs or Sulfadoxine finished pharmaceutical products to another nation, regulatory agencies frequently require a Sulfadoxine WC (written confirmation) as part of the regulatory process.
click here to find a list of Sulfadoxine suppliers with Written Confirmation (WC) on PharmaCompass.
National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Sulfadoxine as an active pharmaceutical ingredient (API).
The FDA updates the NDC directory daily. The NDC numbers for Sulfadoxine API and other APIs are published in this directory by the FDA.
The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.
Pharmaceutical companies that manufacture Sulfadoxine as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.
The NDC directory also contains data on finished compounded human drug products that contain Sulfadoxine and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Sulfadoxine NDC to their finished compounded human drug products, they may choose to do so.
click here to find a list of Sulfadoxine suppliers with NDC on PharmaCompass.
Sulfadoxine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Sulfadoxine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sulfadoxine GMP manufacturer or Sulfadoxine GMP API supplier for your needs.
A Sulfadoxine CoA (Certificate of Analysis) is a formal document that attests to Sulfadoxine's compliance with Sulfadoxine specifications and serves as a tool for batch-level quality control.
Sulfadoxine CoA mostly includes findings from lab analyses of a specific batch. For each Sulfadoxine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Sulfadoxine may be tested according to a variety of international standards, such as European Pharmacopoeia (Sulfadoxine EP), Sulfadoxine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sulfadoxine USP).
LOOKING FOR A SUPPLIER?
