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Chemistry

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Also known as:
Molecular Formula
C18H14N4O5S
Molecular Weight
398.4  g/mol
InChI Key
OQANPHBRHBJGNZ-BKUYFWCQSA-N

Sulfasalazine
1 2D Structure

Sulfasalazine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(3Z)-6-oxo-3-[[4-(pyridin-2-ylsulfamoyl)phenyl]hydrazinylidene]cyclohexa-1,4-diene-1-carboxylic acid
2.1.2 InChI
InChI=1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,20H,(H,19,22)(H,24,25)/b21-13-
2.1.3 InChI Key
OQANPHBRHBJGNZ-BKUYFWCQSA-N
2.1.4 Canonical SMILES
C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NN=C3C=CC(=O)C(=C3)C(=O)O
2.1.5 Isomeric SMILES
C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N/N=C\3/C=CC(=O)C(=C3)C(=O)O
2.2 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 398.4 g/mol
Molecular Formula C18H14N4O5S
XLogP32.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Exact Mass398.06849073 g/mol
Monoisotopic Mass398.06849073 g/mol
Topological Polar Surface Area146 A^2
Heavy Atom Count28
Formal Charge0
Complexity804
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameAzulfidine
PubMed HealthSalicylate (Oral route, Rectal route)
Drug ClassesAntirheumatic, Gastrointestinal Agent
Drug LabelAZULFIDINE EN-tabs Tablets contain sulfasalazine, formulated in a delayed release tablet (enteric-coated), 500 mg, for oral administration.AZULFIDINE EN-tabs Tablets are film coated with cellulose acetate phthalate to retard disintegration of the tab...
Active IngredientSulfasalazine
Dosage FormTablet; Suspension
RouteOral
Strength500mg; 250mg/5ml
Market StatusPrescription
CompanyPharmacia And Upjohn

2 of 6  
Drug NameAzulfidine en-tabs
PubMed HealthSulfasalazine (By mouth)
Drug LabelAZULFIDINE EN-tabs Tablets contain sulfasalazine, formulated in a delayed release tablet (enteric-coated), 500 mg, for oral administration.AZULFIDINE EN-tabs Tablets are film coated with cellulose acetate phthalate to retard disintegration of the tab...
Active IngredientSulfasalazine
Dosage FormTablet; Tablet, delayed release
Routeoral; Oral
Strength500mg
Market StatusPrescription
CompanyPharmacia Upjohn; Pharmacia And Upjohn

3 of 6  
Drug NameSulfasalazine
Drug LabelSulfasalazine Tablets USP, 500 mg for Oral AdministrationTherapeutic classification: Anti-inflammatory agent.Chemical designation: 5-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid.Chemical Structure:The molecular weight of sulfasalazine is 398.39....
Active IngredientSulfasalazine
Dosage FormTablet; Tablet, delayed release
RouteOral
Strength500mg
Market StatusPrescription
CompanyVintage Pharms; Watson Labs

4 of 6  
Drug NameAzulfidine
PubMed HealthSalicylate (Oral route, Rectal route)
Drug ClassesAntirheumatic, Gastrointestinal Agent
Drug LabelAZULFIDINE EN-tabs Tablets contain sulfasalazine, formulated in a delayed release tablet (enteric-coated), 500 mg, for oral administration.AZULFIDINE EN-tabs Tablets are film coated with cellulose acetate phthalate to retard disintegration of the tab...
Active IngredientSulfasalazine
Dosage FormTablet; Suspension
RouteOral
Strength500mg; 250mg/5ml
Market StatusPrescription
CompanyPharmacia And Upjohn

5 of 6  
Drug NameAzulfidine en-tabs
PubMed HealthSulfasalazine (By mouth)
Drug LabelAZULFIDINE EN-tabs Tablets contain sulfasalazine, formulated in a delayed release tablet (enteric-coated), 500 mg, for oral administration.AZULFIDINE EN-tabs Tablets are film coated with cellulose acetate phthalate to retard disintegration of the tab...
Active IngredientSulfasalazine
Dosage FormTablet; Tablet, delayed release
Routeoral; Oral
Strength500mg
Market StatusPrescription
CompanyPharmacia Upjohn; Pharmacia And Upjohn

6 of 6  
Drug NameSulfasalazine
Drug LabelSulfasalazine Tablets USP, 500 mg for Oral AdministrationTherapeutic classification: Anti-inflammatory agent.Chemical designation: 5-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid.Chemical Structure:The molecular weight of sulfasalazine is 398.39....
Active IngredientSulfasalazine
Dosage FormTablet; Tablet, delayed release
RouteOral
Strength500mg
Market StatusPrescription
CompanyVintage Pharms; Watson Labs

API Reference Price

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INDL ESTATE","city":"HYDERABAD.AP","supplier":"VIRCHOW DRUGS LIMITED","supplierCountry":"INDIA","foreign_port":"ISTANBUL","customer":"AYTAK BIOTECH CO.","customerCountry":"TURKEY","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"25.7","totalValueFC":"13668","currency":"EUR","unitRateINR":2296.9575,"date":"22-Oct-2024","totalValueINR":"1148478.75","totalValueInUsd":"13668","indian_port":"Hyderabad Air","hs_no":"29359090","bill_no":"5032423","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"TURKEY","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"PLOT NO.9, S.V.CO-OP. INDL ESTATE, HYDERABAD.AP","customerAddress":""},{"dataSource":"API Import","activeIngredients":"SULFASALAZINE","year":"2021","qtr":"Q2","strtotime":1618857000,"product":"SULFASALAZINE (API) (SULFASALAZINE) (BATCH NO.P-598-D-CN20210101)","address":"B\/2 MAHALAXMI CHAMBERS22 BHULABHAI DESAI ROAD","city":"MUMBAI. MAHARASHTRA","supplier":"ZHEJIANG HISOAR PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"12.06","actualQuantity":"12.06","unit":"KGS","unitRateFc":"60","totalValueFC":"740.1","currency":"USD","unitRateINR":"4569","date":"20-Apr-2021","totalValueINR":"55102.14","totalValueInUsd":"740.1","indian_port":"BOMBAY AIR","hs_no":"29359090","bill_no":"3642741","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS22 BHULABHAI DESAI ROAD"},{"dataSource":"API Import","activeIngredients":"SULFASALAZINE","year":"2021","qtr":"Q2","strtotime":1619375400,"product":"SULFASALAZINE EP\/USP","address":"781, INDUSTRIAL AREA,PHASE-II,","city":"CHANDIGARH.","supplier":"TOCELO PHARMA BV","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"IND SWIFT LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"1750.00","actualQuantity":"1750","unit":"KGS","unitRateFc":"63","totalValueFC":"112768.9","currency":"USD","unitRateINR":"4797.5","date":"26-Apr-2021","totalValueINR":"8395537.5","totalValueInUsd":"112768.9","indian_port":"DELHI AIR","hs_no":"29359090","bill_no":"3712132","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"","customerAddress":"781, INDUSTRIAL AREA,PHASE-II,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1641753000,"product":"SULFASALAZINE","address":"781, INDUSTRIAL AREA,,PHASE-II,","city":"CHANDIGARH,CHANDIGARH","supplier":"PREMIER","supplierCountry":"CHINA","foreign_port":"#N\/A","customer":"IND SWIFT LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"2150.00","actualQuantity":"2150","unit":"KGS","unitRateFc":"69","totalValueFC":"150155.4","currency":"USD","unitRateINR":"5202.6","date":"10-Jan-2022","totalValueINR":"11185590","totalValueInUsd":"150155.4","indian_port":"DELHI AIR","hs_no":"29359090","bill_no":"7029610","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"781, INDUSTRIAL AREA,,PHASE-II,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1675967400,"product":"SULFASALAZINE PH.EUR (CEP GRADE) (GOODS ARE FOR TESTING, ANALYSIS AND DEVELOPMENT PURPOSE ONLY AND NOT FOR COMMERCIAL US","address":"OFFICENO 5-6COMMERCE AVENUE PAUD R D,S NO 127 MAHAGANESH COL KOTHRUD","city":"PUNE,MAHARASHTRA","supplier":"JIANGSU RUIKE PHARMACEUTICAL ","supplierCountry":"CHINA","foreign_port":"NA","customer":"BATAVIA PHARMA PRIVATE ","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"120","totalValueFC":"3005.8","currency":"USD","unitRateINR":"9930","date":"10-Feb-2023","totalValueINR":"248250","totalValueInUsd":"3005.8","indian_port":"BOMBAY AIR","hs_no":"29359090","bill_no":"4582885","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"OFFICENO 5-6COMMERCE AVENUE PAUD R D,S NO 127 MAHAGANESH COL KOTHRUD"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1680546600,"product":"SULFASALAZINE U.S.P. ( FOR R & D UNIT ONLY)","address":"105\/108 REWA CHAMBERS 31 NEW MARINE LINES, Contact No: 28","city":"MUMBAI","supplier":"ADVENTAPHARMA DWC-LLC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"AMOLI ORGANICS","customerCountry":"INDIA","quantity":"60.10","actualQuantity":"60.1","unit":"KGS","unitRateFc":"250","totalValueFC":"15345.1","currency":"USD","unitRateINR":"20925","date":"04-Apr-2023","totalValueINR":"1257592.5","totalValueInUsd":"15345.1","indian_port":"BOMBAY AIR","hs_no":"29359090","bill_no":"5366484","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"105\/108 REWA CHAMBERS 31 NEW MARINE LINES, Contact No: 28"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1684434600,"product":"SULFASALAZINE EP","address":"781, INDUSTRIAL AREA, PHASE-II,","city":"CHANDIGARH","supplier":"PREMIER","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"IND SWIFT LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"69","totalValueFC":"139703.6","currency":"USD","unitRateINR":"5747.7","date":"19-May-2023","totalValueINR":"11495400","totalValueInUsd":"139703.6","indian_port":"DELHI AIR","hs_no":"29359090","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"China","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"","customerAddress":"781, INDUSTRIAL AREA, PHASE-II,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1698690600,"product":"SULFASALAZINE EP","address":"781, INDUSTRIAL AREA,","city":"CHANDIGARH.","supplier":"PREMIER","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"IND SWIFT LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"1500.00","actualQuantity":"1500","unit":"KGS","unitRateFc":"64.5","totalValueFC":"97878.4","currency":"USD","unitRateINR":"5430.9","date":"31-Oct-2023","totalValueINR":"8146350","totalValueInUsd":"97878.4","indian_port":"Delhi Air","hs_no":"29359090","bill_no":"8545052","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"3806 CENTRAL PLAZA 18 HARBOUR ROADWANCHAI Hong Kong, , HONG KONGSDNF HONG KONG","customerAddress":"781, INDUSTRIAL AREA,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1714933800,"product":"SULFASALAZINE U.S.P.","address":"PLOT NO. 221, G.I.D.C.,","city":"GUJARAT","supplier":"ADVENTAPHARMA DWC-LLC","supplierCountry":"UNITED STATES","foreign_port":"CHICAGO O\\'HARE INT\\'L","customer":"AMOLI ORGANICS","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"225","totalValueFC":"68306.4","currency":"USD","unitRateINR":"18978.8","date":"06-May-2024","totalValueINR":"5693625","totalValueInUsd":"68306.4","indian_port":"Bombay Air","hs_no":"29359090","bill_no":"3358457","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"CHICAGO O\\'HARE INT\\'L","supplierAddress":"1802 TRIDENT BAYSIDE DUBAI MARINA,DUBAI U.A.E. P.O.BOX 390667SDNF United Arab Emirates","customerAddress":"PLOT NO. 221, G.I.D.C.,"}]
15-Jan-2021
22-Oct-2024
KGS
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Average Price (USD/KGS)

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Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

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CPHI Middle east
Not Confirmed
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Virtual BoothFaran Shimi: Leading producer of high-quality APIs & alkaloid opiates, serving major pharmaceutical companies across the Middle East.

Grade : Oral

Category : Fillers, Diluents & Binders

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CPHI Middle east
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Virtual BoothBoai NKY Pharmaceuticals Ltd. is one of the largest global PVP suppliers.

Grade : Oral (Pharma Grade)

Category : Fillers, Diluents & Binders

Brand Name : KoVidone® K25

Excipient Details : KoVidone® K25 is used as a low viscosity wet binder in solid dosage forms such as capsules and tablets.

Pharmacopoeia Ref : USP/NF, EP, JP, KP, IP, BP

Technical Specs : NA

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03

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CPHI Middle east
Not Confirmed
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Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

05

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CPHI Middle east
Not Confirmed
  • fda
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  • WHO-GMP

Virtual BoothFaran Shimi: Leading producer of high-quality APIs & alkaloid opiates, serving major pharmaceutical companies across the Middle East.

Grade : Oral

Category : Fillers, Diluents & Binders

06

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CPHI Middle east
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBoai NKY Pharmaceuticals Ltd. is one of the largest global PVP suppliers.

Grade : Oral (Pharma Grade)

Category : Fillers, Diluents & Binders

Brand Name : KoVidone® K30

Excipient Details : KoVidone® K30 is used as a binder for tablets and capsules.

Pharmacopoeia Ref : USP/NF, EP, JP, KP, IP, BP

Technical Specs : NA

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