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Sulforidazine

Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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INTERMEDIATES

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2 Intermediates Suppliers

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

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CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

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API REF. PRICE (USD/KG)

$ 0

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FDF

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FDA Orange Book

Europe

Canada

Australia

South Africa

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Chemistry

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Also known as: Imagotan, Psychoson, Inofal, 14759-06-9, Thioridazine 2-sulfone, Thioridazine-2-sulfone

Molecular Formula

C₂₁H₂₆N₂O₂S₂

Molecular Weight

402.6 g/mol

InChI Key

FLGCRGJDQJIJAW-UHFFFAOYSA-N

FDA UNII

B7599I244X

sulforidazine is a natural product found in Aspergillus fumigatus with data available.

1 2D Structure

Sulforidazine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfonylphenothiazine

2.1.2 InChI

InChI=1S/C21H26N2O2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)26-21-11-10-17(15-19(21)23)27(2,24)25/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3

2.1.3 InChI Key

FLGCRGJDQJIJAW-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)C

2.2 Other Identifiers

2.2.1 UNII

B7599I244X

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. Imagotan

2. Psychoson

3. Inofal

4. 14759-06-9

5. Thioridazine 2-sulfone

6. Thioridazine-2-sulfone

7. Tpn-12

8. Thioridazine Sulfone

9. Thioridazine Sulphone

10. 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylsulfonylphenothiazine

11. 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfonylphenothiazine

12. 10h-phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-

13. B7599i244x

14. Phenothiazine, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylsulfonyl-

15. Solforidazina [dcit]

16. Solforidazina

17. Sulforidazina

18. Sulforidazinum

19. Tpn 12

20. Sulforidazine [inn:dcf]

21. 10h-phenothiazine, 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylsulfonyl)-

22. Sulforidazinum [inn-latin]

23. Sulforidazina [inn-spanish]

24. Einecs 238-818-7

25. Brn 1230366

26. 2-methylsulfonyl-10-[2-(1-methyl-2-piperidyl)ethyl]phenothiazine

27. (+/-)-thioridazine-2-sulfone

28. 2-methylsulfonyl-10-(2-(1-methyl-2-piperidyl)ethyl)phenothiazine

29. Unii-b7599i244x

30. 2-methylsulfonyl-10-(2-(1-methyl-2-piperidyl)ethyl)phenothiazin

31. Sulforidazine [mi]

32. Sulforidazine [inn]

33. Schembl145025

34. Sulforidazine [mart.]

35. Sulforidazine [who-dd]

36. Chembl2107268

37. Bdbm86723

38. Dtxsid30864531

39. Chebi:135644

40. Nsc_31765

41. Akos030239787

42. Cas_14759-06-9

43. Ft-0675190

44. Thioridazine Impurity E [ep Impurity]

45. L000789

46. J-008369

47. Q7636215

48. Thioridazine Hydrochloride Impurity E [ep Impurity]

49. 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-methylsulfonylphenothiazine

50. 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylsulfonyl)-10h-phenothiazine

51. 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-10h-phenothiazine #

52. 2-methanesulfonyl-10-[2-(1-methylpiperidin-2-yl)ethyl]-10h-phenothiazine

53. Phenothiazine, 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylsulfonyl)-

2.4 Create Date

2005-03-27

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₂₆N₂O₂S₂
Molecular Weight	402.6 g/mol
XLogP3	4.6
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Exact Mass	402.14357042 g/mol
Monoisotopic Mass	402.14357042 g/mol
Topological Polar Surface Area	74.3 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	606
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Antidepressive Agents

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)

Antipsychotic Agents

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)

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ABOUT THIS PAGE

Sulforidazine Manufacturers

A Sulforidazine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sulforidazine, including repackagers and relabelers. The FDA regulates Sulforidazine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sulforidazine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sulforidazine Suppliers

A Sulforidazine supplier is an individual or a company that provides Sulforidazine active pharmaceutical ingredient (API) or Sulforidazine finished formulations upon request. The Sulforidazine suppliers may include Sulforidazine API manufacturers, exporters, distributors and traders.

Sulforidazine GMP

Sulforidazine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sulforidazine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sulforidazine GMP manufacturer or Sulforidazine GMP API supplier for your needs.

Sulforidazine CoA

A Sulforidazine CoA (Certificate of Analysis) is a formal document that attests to Sulforidazine's compliance with Sulforidazine specifications and serves as a tool for batch-level quality control.

Sulforidazine CoA mostly includes findings from lab analyses of a specific batch. For each Sulforidazine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sulforidazine may be tested according to a variety of international standards, such as European Pharmacopoeia (Sulforidazine EP), Sulforidazine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sulforidazine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.