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Chemistry

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Also known as: Aldesulfone sodium, Adesulfone sodium, Diasone, 144-75-2, Novotrone, Diasone sodium
Molecular Formula
C14H14N2Na2O6S3
Molecular Weight
448.5  g/mol
InChI Key
AZBNFLZFSZDPQF-UHFFFAOYSA-L
FDA UNII
57OWB0Q221

Sulfoxone
Sulfoxone Sodium is a sodium salt form of sulfoxone, a water-soluble sulfonamide antibiotic used in the treatment of leprosy.
1 2D Structure

Sulfoxone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
disodium;[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate
2.1.2 InChI
InChI=1S/C14H16N2O6S3.2Na/c17-23(18)9-15-11-1-5-13(6-2-11)25(21,22)14-7-3-12(4-8-14)16-10-24(19)20;;/h1-8,15-16H,9-10H2,(H,17,18)(H,19,20);;/q;2*+1/p-2
2.1.3 InChI Key
AZBNFLZFSZDPQF-UHFFFAOYSA-L
2.1.4 Canonical SMILES
C1=CC(=CC=C1NCS(=O)[O-])S(=O)(=O)C2=CC=C(C=C2)NCS(=O)[O-].[Na+].[Na+]
2.2 Other Identifiers
2.2.1 UNII
57OWB0Q221
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Aldesulfon Sodium

2. Diasone

3. Sulfoxone

4. Sulfoxone, Disodium Salt

2.3.2 Depositor-Supplied Synonyms

1. Aldesulfone Sodium

2. Adesulfone Sodium

3. Diasone

4. 144-75-2

5. Novotrone

6. Diasone Sodium

7. Aldapsone

8. Diamidin

9. Diazon

10. Sodium Sulfoxone

11. Sodium Aldesulphone

12. Aldesulphone Sodium

13. Diasone Sodium Enterab

14. Aldesulfone Sodium [inn]

15. Disodium (sulfonylbis(p-phenyleneimino))dimethanesulfinate

16. 57owb0q221

17. Nsc-27222

18. Aldesulfone Sodium (inn)

19. Disodium Formaldehydesulfoxylate-diaminodiphenylsulfone

20. Methanesulfinic Acid, (sulfonylbis(1,4-phenyleneimino))bis-, Disodium Salt

21. Disodium (sulfonylbis(p-phenylenimino))dimethanesulfinate

22. 4:4'-diaminodiphenylsulfone Disodium Formaldehyde Sulfoxylate

23. Aldesulfone [sodium]

24. Nsc 27222; Novotrone; Sodium Aldesulphone; Sodium Sulfoxone

25. Adesulfone Sodium [inn]

26. Aldesulfona Sodica

27. Aldesulfone Sodique

28. Aldesulfonum Natricum

29. Disodium Diformaldehydesulfoxylate

30. Aldesulfona Sodica [inn-spanish]

31. Aldesulfone Sodique [inn-french]

32. Aldesulfonum Natricum [inn-latin]

33. Ncgc00183864-01

34. Nsc 27222

35. Unii-57owb0q221

36. Ai3-23947

37. [sulfonylbis(p-phenyleneimino)]dimethanesulfinic Acid, Disodium Salt

38. Diasone Sodium (tn)

39. Disodium Formaldehyde Sulfoxylate Diamino Diphenylsulfone

40. [4-[4-(sulfinomethylamino)phenyl]sulfonylanilino]methanesulfinic Acid

41. Aniline, 4,4'-sulfonyldi-, Bis(sodium Formaldehydesulfonylate)

42. Aniline, 4,4'-sulfonyldi-, Bis(sodium Formaldehydesulfoxylate)

43. Sulfoxone Sodium [usp]

44. (sulfonylbis(p-phenyleneimino))dimethanesulfinic Acid Disodium Salt

45. Dsstox_cid_3623

46. Dsstox_rid_77116

47. Dsstox_gsid_23623

48. Schembl155722

49. Sulfoxone Sodium [mi]

50. Chembl1200580

51. Dtxsid9023623

52. Aldesulfone Sodium [mart.]

53. Aldesulfone Sodium [who-dd]

54. Ex-a3985

55. Tox21_113217

56. Akos015913824

57. Methanesulfinic Acid, (sulfonylbis(4,1-phenyleneimino))bis-, Disodium Salt

58. Methanesulfinic Acid, (sulfonylbis(p-phenyleneimino))di-, Disodium Salt

59. Sulfoxone Sodium [orange Book]

60. Cas-144-75-2

61. D02521

62. Q4713785

63. Disodium [sulfonylbis(benzene-4,1-diylimino)]dimethanesulfinate

64. Disodium;[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate

65. Methanesulfinic Acid,[sulfonylbis(4,1-phenyleneimino)]bis-,disodium Salt(9ci)

2.4 Create Date
2005-08-01
3 Chemical and Physical Properties
Molecular Weight 448.5 g/mol
Molecular Formula C14H14N2Na2O6S3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count10
Rotatable Bond Count6
Exact Mass447.98093826 g/mol
Monoisotopic Mass447.98093826 g/mol
Topological Polar Surface Area185 Ų
Heavy Atom Count27
Formal Charge0
Complexity509
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 ATC Code

J - Antiinfectives for systemic use

J04 - Antimycobacterials

J04B - Drugs for treatment of lepra

J04BA - Drugs for treatment of lepra

J04BA03 - Aldesulfone sodium


ABOUT THIS PAGE

Sulfoxone Manufacturers

A Sulfoxone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sulfoxone, including repackagers and relabelers. The FDA regulates Sulfoxone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sulfoxone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sulfoxone Suppliers

A Sulfoxone supplier is an individual or a company that provides Sulfoxone active pharmaceutical ingredient (API) or Sulfoxone finished formulations upon request. The Sulfoxone suppliers may include Sulfoxone API manufacturers, exporters, distributors and traders.

Sulfoxone GMP

Sulfoxone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sulfoxone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sulfoxone GMP manufacturer or Sulfoxone GMP API supplier for your needs.

Sulfoxone CoA

A Sulfoxone CoA (Certificate of Analysis) is a formal document that attests to Sulfoxone's compliance with Sulfoxone specifications and serves as a tool for batch-level quality control.

Sulfoxone CoA mostly includes findings from lab analyses of a specific batch. For each Sulfoxone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sulfoxone may be tested according to a variety of international standards, such as European Pharmacopoeia (Sulfoxone EP), Sulfoxone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sulfoxone USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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