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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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$ 0

MARKET PLACE

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDA Orange Book

FDA (Orange Book)

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Canada

Canada

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South Africa

South Africa

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

PATENTS & EXCLUSIVITIES

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US Patents

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US Exclusivities

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Health Canada Patents

DIGITAL CONTENT

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Data Compilation #PharmaFlow

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Stock Recap #PipelineProspector

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Weekly News Recap #Phispers

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News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Sulthiame, 61-56-3, Ospolot, Trolone, Sultiam, Sulphenyltame
Molecular Formula
C10H14N2O4S2
Molecular Weight
290.4  g/mol
InChI Key
HMHVCUVYZFYAJI-UHFFFAOYSA-N
FDA UNII
I00Q766CZ2

Sulthiame
1 2D Structure

Sulthiame

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-(1,1-dioxothiazinan-2-yl)benzenesulfonamide
2.1.2 InChI
InChI=1S/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16)
2.1.3 InChI Key
HMHVCUVYZFYAJI-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CCS(=O)(=O)N(C1)C2=CC=C(C=C2)S(=O)(=O)N
2.2 Other Identifiers
2.2.1 UNII
I00Q766CZ2
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ospolot

2. P-(tetrahydro-2h-1,2-thiazin-2-yl)benzenesulfonamide, S,s-dioxide

3. Sulthiame

4. Sultiam

2.3.2 Depositor-Supplied Synonyms

1. Sulthiame

2. 61-56-3

3. Ospolot

4. Trolone

5. Sultiam

6. Sulphenyltame

7. Sulthiamine

8. Conadil

9. Contravul

10. Riker 594

11. Sultiamum

12. Elisal

13. Bayer A-168

14. Sulthiame [usan]

15. 4-(1,1-dioxothiazinan-2-yl)benzenesulfonamide

16. 4-(1,1-dioxido-1,2-thiazinan-2-yl)benzenesulfonamide

17. Sultiame [inn]

18. Rp-10284

19. P-(tetrahydro-2h-1,2-thiazin-2-yl)benzenesulfonamide, S,s-dioxide

20. Benzenesulfonamide, 4-(tetrahydro-2h-1,2-thiazin-2-yl)-, S,s-dioxide

21. R-594

22. Riker-594

23. Chembl328560

24. 2-(p-sulfamoylphenyl)-tetrahydro-2h-1,2-thiazine 1,1-dioxide

25. Chebi:32171

26. 2h-1,2-thiazine, Tetrahydro-2-(p-sulfamoylphenyl)-, 1,1-dioxide

27. I00q766cz2

28. Sulthiame (usan)

29. Benzenesulfonamide, P-(tetrahydro-2h-1,2-thiazin-2-yl)-, Dioxide

30. Sultiamo

31. Sultiamum [inn-latin]

32. Sultiamo [inn-spanish]

33. Einecs 200-511-0

34. Brn 1222219

35. Rp 10284

36. Unii-i00q766cz2

37. Sulthiame, 2

38. Sulthiame (slt)

39. 2-(4-sulfamoylphenyl)-1,2-thiazixan 1,1-dioxid

40. Ospolot (tn)

41. Sultiame (jp17)

42. 2q1q

43. Sulthiame [mi]

44. Sultiame [jan]

45. Dsstox_cid_3626

46. Sultiame [mart.]

47. Sultiame [who-dd]

48. Dsstox_rid_97552

49. Dsstox_gsid_23626

50. Oprea1_326703

51. Schembl38898

52. Zinc2119

53. Dtxsid4023626

54. Bdbm26999

55. Hms3746a19

56. Bcp30158

57. Tox21_113683

58. 4-(tetrahydro-2h-1,2-thiazin-2-yl)benzenesulfonamide S,s-dioxide

59. Cs-7868

60. Db08329

61. Cas-61-56-3

62. Sultiame 100 Microg/ml In Acetonitrile

63. Ncgc00249907-01

64. As-83082

65. Hy-108316

66. Ft-0674777

67. D01787

68. Q2364943

69. 4-(1,1-dioxido-1,2-thiazinan-2-yl)benzenesulfonamide #

70. 4-(1,1-dioxo-1i>>6-[1,2]thiazinan-2-yl)-benzenesulfonamide

71. P-(tetrahydro-2h-1,2-thiazin-2-yl)benzenesulfonamide Dioxide

72. 4-(1,1-dioxo-1$l^{6},2-thiazinan-2-yl)benzene-1-sulfonamide

73. 4-(tetrahydro-1,1-dioxido-2h-1,2-thiazin-2-yl)benzenesulfonamide

74. 4-(tetrahydro-2h-1,2-thiazin-2-yl)benzenesulfonamide, S,s-dioxide

75. Osp

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 290.4 g/mol
Molecular Formula C10H14N2O4S2
XLogP30.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass290.03949928 g/mol
Monoisotopic Mass290.03949928 g/mol
Topological Polar Surface Area114 Ų
Heavy Atom Count18
Formal Charge0
Complexity481
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anticonvulsants

Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)


4.2 ATC Code

N - Nervous system

N03 - Antiepileptics

N03A - Antiepileptics

N03AX - Other antiepileptics

N03AX03 - Sultiame


API SUPPLIERS

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01

Arevipharma

Germany

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM
Not Confirmed
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Arevipharma

Germany

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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BIO Partnering at JPM
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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Listed Suppliers

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01

Arevipharma

Germany
BIO Partnering at JPM
Not Confirmed
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Arevipharma

Germany
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BIO Partnering at JPM
Not Confirmed

Sulthiame

About the Company : Arevipharma GmbH is a modern manufacturer of active pharmaceutical ingredients and intermediates with more than 140 years of expertise. Our customers are generic and research-based...

Arevipharma GmbH is a modern manufacturer of active pharmaceutical ingredients and intermediates with more than 140 years of expertise. Our customers are generic and research-based pharmaceutical companies on five continents. Our business partners recognise us as a competent, reliable and efficient company that is distinguished by individual service and an innovative character. The company’s 140 year history is based on the knowledge, skills, commitment and loyalty of its employees. Arevipharma also feels committed to its owners and investors. Due to the consistent expansion of new technologies,
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FDF Dossiers

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BIO Partnering at JPM
Not Confirmed
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BIO Partnering at JPM
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Sultiamum

Brand Name : Ospolot

Dosage Form : Film-Coated Tablets

Dosage Strength : 200mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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BIO Partnering at JPM
Not Confirmed
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BIO Partnering at JPM
Not Confirmed

Sultiamum

Brand Name : Ospolot

Dosage Form : Film-Coated Tablets

Dosage Strength : 50mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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03

Neuraxpharm

Spain
BIO Partnering at JPM
Not Confirmed
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Neuraxpharm

Spain
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BIO Partnering at JPM
Not Confirmed

Sulthiame

Brand Name :

Dosage Form : Film Coated Tablet

Dosage Strength : 50MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Spain

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04

Neuraxpharm

Spain
BIO Partnering at JPM
Not Confirmed
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Neuraxpharm

Spain
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BIO Partnering at JPM
Not Confirmed

Sulthiame

Brand Name :

Dosage Form : Film Coated Tablet

Dosage Strength : 100MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Spain

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05

Neuraxpharm

Spain
BIO Partnering at JPM
Not Confirmed
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Neuraxpharm

Spain
arrow
BIO Partnering at JPM
Not Confirmed

Sulthiame

Brand Name :

Dosage Form : Film Coated Tablet

Dosage Strength : 200MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Spain

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06

Phebra

Australia
BIO Partnering at JPM
Not Confirmed
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Phebra

Australia
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BIO Partnering at JPM
Not Confirmed

sulthiame

Brand Name : Ospolot

Dosage Form : tablet

Dosage Strength : 50 mg

Packaging : 200

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

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07

Phebra

Australia
BIO Partnering at JPM
Not Confirmed
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Phebra

Australia
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BIO Partnering at JPM
Not Confirmed

sulthiame

Brand Name : Ospolot

Dosage Form : tablet

Dosage Strength : 200 mg

Packaging : 200

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

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08

Phebra

Australia
BIO Partnering at JPM
Not Confirmed
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Phebra

Australia
arrow
BIO Partnering at JPM
Not Confirmed

sulthiame

Brand Name : Ospolot

Dosage Form : tablet

Dosage Strength : 50 mg

Packaging : 200

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

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09

Phebra

Australia
BIO Partnering at JPM
Not Confirmed
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Phebra

Australia
arrow
BIO Partnering at JPM
Not Confirmed

sulthiame

Brand Name : Ospolot

Dosage Form : tablet

Dosage Strength : 200 mg

Packaging : 200

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

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ABOUT THIS PAGE

Sulthiame Manufacturers

A Sulthiame manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sulthiame, including repackagers and relabelers. The FDA regulates Sulthiame manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sulthiame API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Sulthiame manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Sulthiame Suppliers

A Sulthiame supplier is an individual or a company that provides Sulthiame active pharmaceutical ingredient (API) or Sulthiame finished formulations upon request. The Sulthiame suppliers may include Sulthiame API manufacturers, exporters, distributors and traders.

click here to find a list of Sulthiame suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sulthiame GMP

Sulthiame Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sulthiame GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sulthiame GMP manufacturer or Sulthiame GMP API supplier for your needs.

Sulthiame CoA

A Sulthiame CoA (Certificate of Analysis) is a formal document that attests to Sulthiame's compliance with Sulthiame specifications and serves as a tool for batch-level quality control.

Sulthiame CoA mostly includes findings from lab analyses of a specific batch. For each Sulthiame CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sulthiame may be tested according to a variety of international standards, such as European Pharmacopoeia (Sulthiame EP), Sulthiame JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sulthiame USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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