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Chemistry

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Also known as: 23694-17-9, Sultopride hcl, N-((1-ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide hydrochloride, Sultopridehcl, Lin-1418 hydrochloride, Sultopride hydrochloride [jan]
Molecular Formula
C17H27ClN2O4S
Molecular Weight
390.9  g/mol
InChI Key
IGOWMQPOGQYFFM-UHFFFAOYSA-N
FDA UNII
8Q6926T32J

Sultopride HCl
A benzamide derivative that is used as an antipsychotic agent for the treatment of schizophrenia. It is also used as an antidepressive agent.
1 2D Structure

Sultopride HCl

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide;hydrochloride
2.1.2 InChI
InChI=1S/C17H26N2O4S.ClH/c1-4-19-10-6-7-13(19)12-18-17(20)15-11-14(24(21,22)5-2)8-9-16(15)23-3;/h8-9,11,13H,4-7,10,12H2,1-3H3,(H,18,20);1H
2.1.3 InChI Key
IGOWMQPOGQYFFM-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)CC)OC.Cl
2.2 Other Identifiers
2.2.1 UNII
8Q6926T32J
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-amino-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide

2. Amisulpride

3. Barnetil

4. Dan 2163

5. Dan-2163

6. Lin 1418

7. Lin-1418

8. N-(ethyl-1-pyrrolidinyl- 2-methyl)methoxy-2-ethylsulfonyl-5-benzamide

9. Solian

10. Sultopride

2.3.2 Depositor-Supplied Synonyms

1. 23694-17-9

2. Sultopride Hcl

3. N-((1-ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide Hydrochloride

4. Sultopridehcl

5. Lin-1418 Hydrochloride

6. Sultopride Hydrochloride [jan]

7. Barnotil

8. N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulphonyl)-2-methoxybenzamide Hydrochloride

9. 8q6926t32j

10. 55619-22-2

11. Dsstox_cid_28996

12. Dsstox_rid_83261

13. Dsstox_gsid_49070

14. Benzamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-, Hydrochloride (1:1)

15. Sultopride Hydrochloride (jan)

16. Cas-23694-17-9

17. Ncgc00185771-01

18. Unii-8q6926t32j

19. N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide Hydrochloride

20. Barnetil (tn)

21. Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxy-, Hydrochloride (1:1)

22. N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide Hydrochloride

23. Einecs 245-829-0

24. Ncgc00184999-01

25. Sultopride Monohydrochloride

26. Schembl1417863

27. Chembl3182384

28. Dtxsid0049070

29. Ex-a3336

30. Tox21_113625

31. Tox21_113626

32. Hy-42849a

33. Sultopride Hydrochloride [mi]

34. Akos016010186

35. Ac-4565

36. Sultopride Hydrochloride [who-dd]

37. As-16926

38. Cs-0040603

39. Ft-0659859

40. D02208

41. 694s179

42. A816850

43. Sultopride Hydrochloride (lin-1418 Hydrochloride)

44. J-015185

45. Q27270888

46. N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulphonyl)-2-methoxybenzamide Monohydrochloride

47. N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-5-(ethylsulfonyl)benzamide Hydrochloride

48. N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide Monohydrochloride

49. N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide; Hydron; Chloride

50. N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide;hydrochloride

51. Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxy-, Monohydrochloride

52. O-anisamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-, Monohydrochloride

2.4 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 390.9 g/mol
Molecular Formula C17H27ClN2O4S
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Exact Mass390.1380062 g/mol
Monoisotopic Mass390.1380062 g/mol
Topological Polar Surface Area84.1 Ų
Heavy Atom Count25
Formal Charge0
Complexity517
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antidepressive Agents, Second-Generation

A structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake. (See all compounds classified as Antidepressive Agents, Second-Generation.)


Antipsychotic Agents

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)


Dopamine Antagonists

Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME. (See all compounds classified as Dopamine Antagonists.)


ABOUT THIS PAGE

Sultopride HCl Manufacturers

A Sultopride HCl manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sultopride HCl, including repackagers and relabelers. The FDA regulates Sultopride HCl manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sultopride HCl API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Sultopride HCl Suppliers

A Sultopride HCl supplier is an individual or a company that provides Sultopride HCl active pharmaceutical ingredient (API) or Sultopride HCl finished formulations upon request. The Sultopride HCl suppliers may include Sultopride HCl API manufacturers, exporters, distributors and traders.

click here to find a list of Sultopride HCl suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sultopride HCl JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Sultopride HCl Drug Master File in Japan (Sultopride HCl JDMF) empowers Sultopride HCl API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Sultopride HCl JDMF during the approval evaluation for pharmaceutical products. At the time of Sultopride HCl JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Sultopride HCl suppliers with JDMF on PharmaCompass.

Sultopride HCl GMP

Sultopride HCl Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sultopride HCl GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sultopride HCl GMP manufacturer or Sultopride HCl GMP API supplier for your needs.

Sultopride HCl CoA

A Sultopride HCl CoA (Certificate of Analysis) is a formal document that attests to Sultopride HCl's compliance with Sultopride HCl specifications and serves as a tool for batch-level quality control.

Sultopride HCl CoA mostly includes findings from lab analyses of a specific batch. For each Sultopride HCl CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sultopride HCl may be tested according to a variety of international standards, such as European Pharmacopoeia (Sultopride HCl EP), Sultopride HCl JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sultopride HCl USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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